Chii chinonzi Istradefylline: Zvinoshandiswa, Madosi, Migumisiro Yemuviri uye Zvimwe

Istradefylline mushonga unobatsira kubata zviitiko zve "off" mu chirwere cheParkinson's kana kurapwa kwako kwenguva dzose kusingashandi sezvazvinofanira kuita. Kana iwe kana mumwe munhu waunotarisira ari kutarisana nechirwere cheParkinson's, unogona kunge wakaona kuti dzimwe nguva mishonga mikuru inoita seinoshanda isati yasvika dose inotevera, ichikusiya uchinzwa wakaoma kana uine dambudziko rekufamba zvakanaka.

Mushonga uyu unoshanda sekuwedzera kurapwa pamwe chete nemishonga yako iripo yeParkinson's. Yakagadzirirwa kubatsira kuderedza nguva idzodzo dzinoshungurudza apo zviratidzo zvako zvinodzoka pakati pemadosi, zvichikupa zororo rakawanda zuva rese.

Chii chinonzi Istradefylline?

Istradefylline imhando yemushonga unonzi adenosine A2A receptor antagonist. Mumashoko ari nyore, inoshanda nekudzivisa zviratidzo zvakasiyana-siyana muuropi hwako zvinogona kukanganisa kufamba kwakatsetseka uye kubatanidzwa.

Funga nezvayo semushonga unobatsira unoshanda pamwe chete nekurapa kwako kukuru kweParkinson's. Nepo mushonga wako wekutanga (kazhinji levodopa/carbidopa) uchipa mabhenefiti makuru, istradefylline inopinda mukubatsira kuchengetedza mabhenefiti iwayo zvakanyanya zuva rese.

Mushonga uyu unouya muchimiro chepiritsi uye unotorwa nemuromo. Yakanyatsogadzirirwa vanhu vakuru vane chirwere cheParkinson's vanowana mota fluctuations, ndiyo nguva idzodzo apo zviratidzo zvako zvinoita sezinouya nekufamba zvisingatarisirwi.

Chii chinonzi Istradefylline chinoshandiswa?

Istradefylline inonyanya kushandiswa kurapa zviitiko zve "off" muvanhu vane chirwere cheParkinson's. Zviitiko izvi zve "off" inzira apo mushonga wako wenguva dzose weParkinson's unoita sekumira kushanda zvakanaka, uye zviratidzo zvako zvakaita sekudedera, kuoma, uye kufamba zvishoma zvinodzoka.

Vanhu vazhinji vane chirwere cheParkinson vanopedzisira vachisangana nekuchinja uku sezvo mamiriro avo achiwedzera. Ungaona kuti mushonga wako unoshanda zvakanaka kwemaawa mashoma mushure mekuutora, asi wobva watanga kunzwa wakaoma kana kudedera zvakare usati watora mushonga wako unotevera.

Mushonga uyu unogara uchishandiswa pamwe chete nelevodopa/carbidopa, haushandiswe wega. Wakagadzirirwa kubatsira kuwedzera nguva dzaunonzwa zvakanaka uye kuderedza nguva yaunopedza mumamiriro ekusagadzikana iwayo.

Istradefylline Inoshanda Sei?

Istradefylline inoshanda nekudzivisa adenosine A2A receptors muuropi hwako. Aya ma receptors anowanzoita kuti basa re dopamine rinonoke, kemikari yeuropi inobatsira kudzora kufamba uye inoshayikwa muchirwere cheParkinson.

Nekudzivisa aya ma receptors, istradefylline inobvumira dopamine kuti ishande zvakanyanya. Izvi zvinoreva kuti mushonga wako weParkinson uripo unogona kupa mabhenefiti akawanda zuva rese, kuderedza nguva idzodzo dzinoshungurudza.

Inoonekwa semushonga wepakati nepakati uyo unopa rutsigiro rwakagadzikana panzvimbo pekuchinja kukuru. Vanhu vazhinji vanoona kuvandudzwa zvishoma nezvishoma munguva yavo yekuzorora kwemavhiki akati wandei ekurapa, panzvimbo pezvinoitika zvakanyanya nekukurumidza.

Ndingatora Sei Istradefylline?

Tora istradefylline sezvakanyorwa nachiremba wako, kazhinji kamwe pazuva. Unogona kuitora uine chikafu kana usina, chero chiri nyore kwauri.

Zvakanakisa kutora mushonga wako panguva imwe chete zuva rega rega kubatsira kuchengetedza mazinga akagadzikana mumuviri wako. Vanhu vazhinji vanoona zvichibatsira kuitora nemishonga yavo yemangwanani sechikamu chetsika yavo yezuva nezuva.

Kana uine dambudziko rekumedza mahwendefa, unogona kupwanya mahwendefa eistradefylline woasanganisa neapuro sauce kana pudding. Zvisinei, usatsenga kana kuputsa mahwendefa kunze kwekunge chiremba wako akakuudza zvakananga kuti zvakanaka kuita kudaro.

Rambai muchitora mishonga yenyu yese yeParkinson sezvakanyorwa. Istradefylline yakagadzirirwa kushanda pamwe chete nemushonga wenyu uripo, kwete kuutsiva.

Ndingatora Istradefylline Kwenguva Yakareba Sei?

Istradefylline inowanzoita mushonga wenguva refu waunozoramba uchitora chero bedzi uchibatsira kudzora zviratidzo zveParkinson. Vanhu vazhinji vanobatsirwa nemushonga uyu vanofanira kuutora kwenguva isingagumi kuti vachengetedze kuvandudzwa.

Mungatanga kuona zvimwe zvakanaka mukati memavhiki mashoma ekutanga, asi zvinogona kutora kusvika kumavhiki gumi nemaviri kuti muone mhedzisiro yakazara. Kuvandudzwa uku zvishoma nezvishoma kwakajairika uye hakurevi kuti mushonga haushandi.

Chiremba wenyu achatarisa nguva dzose kuti mushonga uri kushanda sei kwamuri uye anogona kuchinja chirongwa chenyu chekurapa nekufamba kwenguva. Usambomira kutora istradefylline kamwe kamwe usina kukurukura nazvo nemupi wenyu wehutano kutanga, sezvo izvi zvingaita kuti zviitiko zvenyu zvekunze zvidzoke kana kuipa.

Ndezvipi Zvakaipa ZveIstradefylline?

Semishonga yese, istradefylline inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anoiona. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakagadzirira uye uzive kuti ungataurirana riini nachiremba wako.

Mhedzisiro inowanzoitika inowanzoita nyoro uye inowanzoita nani sezvo muviri wako uchigadzirisa kumushonga:

• Kusvotwa kana dumbu risingafare
• Dizziness kana lightheadedness
• Kutambudzika kurara kana shanduko mumaitiro ekurara
• Kuvharika
• Hallucinations (kuona kana kunzwa zvinhu zvisipo)

Mhedzisiro iyi inowanzoita isinganyanyi kuoneka mushure memavhiki mashoma ekurapa. Kutora mushonga nechikafu kunogona kubatsira kuderedza kusvotwa, uye kugara uine mvura yakakwana kunogona kubatsira nekuzvimbirwa.

Vamwe vanhu vanogona kuona mhedzisiro yakakomba inoda kutarisirwa kwekurapa. Kunyange izvi zvisingawanzoitiki, zvakakosha kuziva zvekutarisa:

• Kuda zvinhu zvisina kujairika kana maitiro (sekubheja zvakanyanya, kutenga, kana kudya)
• Kuchinja kukuru kwemanzwiro kana kuora mwoyo
• Kuwedzera kukuru mukufamba kusingadzoreki
• Kurwadziwa muchipfuva kana kurova kwemoyo kusingaite zvakanaka
• Dizziness yakanyanya kana kufenda

Kana ukaona chero chimwe chezvinhu izvi zvakakomba, taura nachiremba wako nekukurumidza. Vanogona kubatsira kuona kana mushonga uchida kuchinjwa kana kana uchida rubatsiro rwakawedzerwa.

Ndiani Asingafaniri Kutora Istradefylline?

Istradefylline haikodzeri munhu wese, uye mamwe mamiriro ehutano kana mishonga inogona kuita kuti isachengeteke. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akurudzira mushonga uyu.

Haufaniri kutora istradefylline kana uine allergic kwairi kana chero chimwe chezvinhu zvayo. Udza chiremba wako nezve chero allergic reactions kumishonga, kunyangwe dzichitaridzika sedzisina hukama.

Vanhu vane mamwe mamiriro ehutano vangangoda kuongororwa zvakakosha kana vangangotadza kutora mushonga uyu zvakachengeteka:

• Kutadza kwakanyanya kweitsvo
• Kutadza kwakanyanya kwechiropa
• Nhoroondo yematambudziko emoyo
• Psychosis inoshanda kana mamiriro akakomba ehutano hwepfungwa
• Kuzvitakura kana kuyamwisa

Mishonga mimwe inogona kuita interaction neistradefylline, zvichigona kuita kuti isashande zvakanaka kana kuwedzera mhedzisiro. Ita shuwa kuti waudza chiremba wako nezve mishonga yese yaunotora, kusanganisira mishonga isingatengeswe uye zvinowedzerwa.

Istradefylline Zita reBrand

Istradefylline inotengeswa pasi pezita rebrand Nourianz muUnited States. Iyi ndiyo nzira yakajairika yaunozoona ichirairwa uye ichigoverwa kumafemu.

Paunenge uchitaura nachiremba wako kana pharmacist, unogona kushandisa zita re generic (istradefylline) kana zita rebrand (Nourianz). Vachanzwisisa chaizvo kuti urikureva mushonga upi.

Parizvino, Nourianz ndiyo chete mhando iripo muU.S., kunyangwe mhando dzisiri dzekambani dzinogona kuwanikwa mune ramangwana sezvo marezinesi achipera.

Zvimwe Zvinogona Kushandiswa Panzvimbo peIstradefylline

Kana istradefylline isiri iyo yakakunakira, pane mamwe mishonga inogona kubatsira kutarisira zviitiko zvekunze muParkinson's disease. Chiremba wako anogona kukurukura izvi zvingasarudzwa zvichienderana nemamiriro ako chaiwo.

Mamwe mishonga anoshanda zvakafanana kuderedza nguva yekunze anosanganisira:

\n
• Safinamide (Xadago) - imwe mishonga yekuwedzera
\n
• Rasagiline (Azilect) - MAO-B inhibitor
\n
• Selegiline (Eldepryl) - imwe MAO-B inhibitor
\n
• Entacapone (Comtan) - COMT inhibitor
\n

Chiremba wako anogonawo kufunga nezvekugadzirisa chirongwa chako chemishonga yelevodopa/carbidopa kana kuchinjira kune imwe fomu usati wawedzera mushonga mutsva. Sarudzo yakanakisa inoenderana nezviratidzo zvako zvakananga, mamwe mamiriro ehutano, uye maitiro ako kumishonga yapfuura.

Ko Istradefylline Zviri Nani Kudarika Rasagiline?

Zvese istradefylline ne rasagiline zvinogona kubatsira kuderedza zviitiko zvekunze muParkinson's disease, asi zvinoshanda kuburikidza nemaitiro akasiyana muuropi hwako. Hapana mhinduro iri nyore yekuti ndeipi iri

Vanhu vane chirwere chemoyo vanogona kutora istradefylline zvakachengeteka, asi vangada kuongororwa zvakanyanya. Mushonga uyu dzimwe nguva unogona kukanganisa rhythm yemoyo, saka chiremba wako achada kuongorora hutano hwemoyo wako zvakanyatsonaka usati watanga kurapwa.

Kana uine nhoroondo yematambudziko emoyo, chiremba wako angaraira EKG (muedzo werhythm yemoyo) usati watanga kutora istradefylline uye pamwe panguva yekurapwa. Izvi zvinobatsira kuona kuti mushonga haukanganisi rhythm yemoyo wako.

Usarega matambudziko emoyo achikutadzisa kukurukura sarudzo yekurapa iyi nachiremba wako. Vanhu vazhinji vane mamiriro emoyo vanotora istradefylline zvakabudirira nekutarisa kwakakodzera.

Q2. Ndingaita Sei Kana Ndakatora Istradefylline Yakawandisa Netsaona?

Kana netsaona ukatora istradefylline yakawanda kupfuura yakarairwa, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira. Kutora zvakanyanya kunogona kuwedzera njodzi yako yemigumisiro yakaita senausea, dzungu, kana shanduko yerhythm yemoyo.

Usaedze "kuenzanisa" mushonga wekuwedzera nekusvetuka unotevera. Panzvimbo pezvo, tevera gwara kubva kumupi wako wehutano kana nzvimbo yekudzora muchetura nezve zvekutevera.

Kuti udzivise overdoses netsaona, funga kushandisa chirongwa chemishonga kana kumisa zviyeuchidzo zvefoni kuti zvikubatsire kuchengeta zvekuti watora mushonga wako rini.

Q3. Ndingaita Sei Kana Ndikakanganwa Dose yeIstradefylline?

Kana ukakanganwa dose yeistradefylline, itore pakarepo paunoyeuka, kunze kwekunge yava nguva yechikamu chako chinotevera. Muchiitiko ichocho, sveta dose yakakanganwa uye uenderere mberi nechirongwa chako chetsika.

Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yakakanganwa. Izvi zvinogona kuwedzera njodzi yako yemigumisiro pasina kupa mamwe mabhenefiti.

Kana iwe uchikanganwa madosi kazhinji, taura nachiremba wako nezve nzira dzekukubatsira kuyeuka, sekutora panguva imwe chete nemumwe mushonga wezuva nezuva kana kumisa alarm yefoni.

Q4. Ndingamira Rini Kutora Istradefylline?

Unofanira kungomira kutora istradefylline pasi pekutungamirirwa nachiremba wako. Sezvo yakagadzirirwa kubatsira kudzora zviratidzo zveParkinson zviri kuenderera mberi, kuimisa zvichaita kuti zviitiko zvako zvioneke zvakare.

Chiremba wako angakurudzira kumisa mushonga kana uri kusangana nemigumisiro yakakosha inodarika mabhenefiti, kana kana chirwere chako cheParkinson chakaenda kune imwe nzvimbo apo mamwe marapirwo angave akakodzera.

Kana iwe nachiremba wako mukasarudza kumisa istradefylline, iwe unowanzo rega zvishoma nezvishoma pane kumira kamwe kamwe. Izvi zvinobatsira kudzivirira chero kuwedzera kwakashata kwezviratidzo zvako.

Q5. Ndinganwa Doro Ndiri Kutora Istradefylline Here?

Zvinowanzoita zvakanaka kuderedza doro uchitora istradefylline. Doro rinogona kuwedzera njodzi yekutenderera uye rinogona kukanganisa mashandiro emushonga.

Kana iwe ukasarudza kunwa dzimwe nguva, ita izvi zvine mwero uye teerera kuti unonzwa sei. Vamwe vanhu vanowana kuti kunyange huwandu hudiki hwedoro hunovaita kuti vanzwe vasina kugadzikana kana kutenderera kana zvichibatanidzwa nemushonga uyu.

Taura nachiremba wako nezve tsika dzako dzekushandisa doro kuitira kuti vakwanise kupa gwara rakagadzirirwa zvinoenderana nehutano hwako hwese nemamwe mishonga yaunotora.