Chii chinonzi Ivabradine: Zvinoshandiswa, Dosage, Side Effects uye Zvimwe

Ivabradine mushonga wemoyo unobatsira kuderedza kumhanya kwemoyo wako kana uchirova nekukurumidza. Inoshanda zvakasiyana nemimwe mishonga yemoyo nekunangana nechikamu chakati chemaitiro emagetsi emoyo wako anonzi "funny current" kana If current. Izvi zvinoita kuti zvive zvakanyanya kubatsira kune vanhu vane moyo inokurumidza kunyangwe pavanenge vakazorora, zvichivabatsira kunzwa vakasununguka uye kuderedza kushushikana pamusoro pemhasuru dzemoyo wavo.

Chii chinonzi Ivabradine?

Ivabradine mushonga unopiwa nachiremba uyo ari muboka remishonga inonzi hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. Muchidimbu, inodzora kumhanya kwemoyo inoshanda nekudzivisa zviratidzo zvemagetsi mumoyo mako. Kusiyana nebeta-blockers kana calcium channel blockers, ivabradine inonyanya kunangana neiyo moyo wako wechisikigo pacemaker isina kukanganisa ropa rako kana simba rekurova kwemoyo wako.

Mishonga yakagadzirirwa kugadzirisa chido chakati chevanhu vane moyo inokurumidza, kunyanya avo vane moyo kutadza kana angina yakagadzikana. Inopa nzira yakasiyana yekugadzirisa kumhanya kwemoyo iyo inogona kubatsira zvakanyanya kana mimwe mishonga isina kukodzera kana isina kukwana yega.

Ivabradine Inoshandiswa Kunei?

Ivabradine inonyanya kunyorerwa mamiriro maviri makuru emoyo uko kudzora kumhanya kwemoyo kwakakosha kuhutano hwako. Chiremba wako angakurudzira mushonga uyu kana moyo wako uchiramba uchirova nekukurumidza, uchiisa kushushikana kwakawanda pane yako cardiovascular system.

Chinhu chikuru chekutanga chekushandisa ndechokushaya simba kwemoyo kwenguva refu muvanhu vakuru vane rhythm yemoyo yakajairika asi avo moyo wavo unogara uri pamusoro pe70 beats paminiti kunyangwe vachitora mushonga webeta-blockers wakanyanya. Muchiitiko ichi, ivabradine inobatsira kuderedza basa pamoyo wako, ichiita kuti upombe zvakanyanya uye zvichigona kuvandudza zviratidzo zvako zvakaita sekufema nekuneta.

Chinhu chechipiri chikuru chekushandisa ndechokurwadziwa kwemoyo kwenguva refu, uko kurwadziwa muchipfuva kunoitika kana moyo wako usingawani ropa rakakwana rakazara neoksijeni. Kana beta-blockers isina kukodzera iwe kana isingapi kutonga kwakakwana, ivabradine inogona kubatsira kuderedza rhythm yemoyo wako uye kuderedza kakawanda kwezviitiko zveangina.

Ivabradine Inoshanda Sei?

Ivabradine inoshanda nekunanga pacemaker yako yemoyo, kunyanya kuvhara

Ivabradine inofanira kutorwa sezvakarairwa nachiremba wako, kazhinji kaviri pazuva pamwe chete nezvokudya. Kuitora nezvokudya kunobatsira muviri wako kutora mushonga zvakanaka uye kunogona kuderedza mukana wekugumbuka mudumbu. Nguva yekutora mishonga yako inofanira kuva yakafanana sezvinobvira, kazhinji maawa anenge 12 akasiyana.

Unogona kutora ivabradine nemukaka, mvura, kana chero chinwiwa chisina doro panguva yezvokudya zvako. Chinhu chakanyanya kukosha kuva nezvimwe zvokudya mudumbu rako paunotora mushonga wega wega. Izvi hazvifaniri kuva chikafu chikuru - kunyange chikafu chakareruka kana kudya kwemangwanani kuduku uye kudya kwemanheru kuchashanda zvakanaka.

Chiremba wako anogona kukutanga pamushonga wakaderera uye zvishoma nezvishoma kuwedzera zvichienderana nekuti moyo wako unopindura sei uye kuti unotsungirira sei mushonga. Usambofa wakachinja mushonga wako wega, sezvo kurova kwemoyo wako kuchida kuongororwa zvakanyatsonaka kuti uve nechokwadi chekuti mushonga uri kushanda zvakachengeteka uye zvinobudirira.

Kana uchida kurega kutora ivabradine, chiremba wako achakutungamira mukuderedzwa zvishoma nezvishoma pane kumira kamwe kamwe. Izvi zvinobatsira kudzivirira chero zvingaitika zvekudzoka pamoyo wako.

Ndingatora Ivabradine Kwenguva Yakareba Sei?

Ivabradine inowanzo kurairwa semushonga wenguva refu, zvinoreva kuti unogona kuitora kwemwedzi kana makore pane kwemavhiki mashoma chete. Nguva chaiyo inoenderana nemamiriro ako emoyo uye kuti unopindura sei kurapwa.

Kune vanhu vane kukundikana kwemoyo kusingaperi, ivabradine inowanzoita chikamu chechirongwa chekurapa kwenguva refu pamwe chete nemimwe mishonga yemoyo. Chiremba wako achagara achiongorora kurova kwemoyo wako uye basa remoyo rose kuti aone kana mushonga ucharamba uchikubatsira.

Kana uri kutora ivabradine ye chronic stable angina, nguva yekurapa inoenderana nezviratidzo zvako uye kuti mamwe marapirwo ari kushanda sei. Vamwe vanhu vangada kuitora zvachose, nepo vamwe vachikwanisa kuideredza kana kuimisa kana mamiriro avo akavandudzwa nekuchinja mararamiro kana mamwe marapirwo.

Chiremba wako achaita hurongwa hwekuongorora nguva dzose kuti aone kana uchifanira kuramba uchitora ivabradine. Vachafunga nezvezvinhu zvakaita semhinduro yemoyo wako, chero mhedzisiro yaunowana, uye shanduko muhutano hwemoyo wako hwese.

Ndezvipi Zvinokonzerwa neIvabradine?

Semishonga yese, ivabradine inogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachizvitsungirira zvakanaka. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakavimbika nezvekurapa kwako uye kuziva nguva yekubata chiremba wako.

Mhedzisiro yakajairika yaungasangana nayo inosanganisira matambudziko ekuona, kunyanya kuona mwenje wakajeka kana halos kutenderedza mwenje. Izvi zvinoitika nekuti ivabradine inogona kukanganisa mabasa emagetsi mumuromo wemaziso ako. Shanduko idzi dzekuona dzinowanzoita dzekanguva uye dzinowanzoita nani sezvo muviri wako uchigadzirisa kumushonga.

Heano mhedzisiro yakajairika iyo vanhu vanoshuma:

• Zviitiko zvinopenya kana phosphenes (kuona nzvimbo dzakajeka kana kupenya kwemwenje)
• Kusaona zvakanaka, kunyanya mumwenje wakajeka
• Kurova kwemoyo kunonoka (bradycardia)
• Musoro
• Dizziness kana lightheadedness
• Kuneta kana kunzwa kuneta zvisingaite

Mhedzisiro iyi inowanzoita nyoro uye inowanzoita nani nekufamba kwenguva sezvo muviri wako uchijaira mushonga. Vanhu vazhinji vanowana kuti vanogona kuenderera mberi nemabasa avo ezuva nezuva pasina kukanganiswa kukuru.

Zvimwe zvisingawanzoitiki asi zvakanyanya mhedzisiro inoda kutarisirwa kwekurapa nekukasira. Kunyangwe zvisingawanzoitiki, unofanirwa kuziva zvingaitika izvi kuti ugone kutsvaga rubatsiro kana zvichidikanwa.

• Kurova kwemoyo kusina kujairika (atrial fibrillation)
• Kurova kwemoyo kunonoka zvakanyanya (pasi pe50 beats paminiti)
• Kurwadziwa muchipfuva kana kuwedzera angina
• Dizziness yakanyanya kana kufenda
• Kupfupika kwekufema kana kuoma kufema

Kana uine chero chimwe chezviratidzo izvi zvakakomba, fonera chiremba wako nekukasika kana kutsvaga rubatsiro rwekurapa rwechimbichimbi. Kuchengeteka kwako ndiko kunonyanya kukosha, uye zviratidzo izvi zvinoda kuongororwa nekukurumidza.

Ndiani Asingafaniri Kutora Ivabradine?

Ivabradine haikodzeri munhu wese, uye pane mamiriro akati wandei apo chiremba wako aisazonyora mushonga uyu. Kunzwisisa izvi zvinopesana kunobatsira kuona kuchengeteka kwako uye kushanda kwepurani yako yekurapa.

Haufaniri kutora ivabradine kana uine matambudziko emoyo akati wandei, kunyanya kana usina rhythm yakajairika ye sinus. Mushonga uyu wakagadzirirwa kushanda ne pacemaker yemoyo wako, saka haushande kana kuchengeteka kune vanhu vane rhythms yemoyo isina kujairika senge atrial fibrillation.

Heano mamiriro makuru angakutadzise kutora ivabradine:

• Kurova kwemoyo panguva yekuzorora pasi pe 70 beats paminiti usati watanga kurapwa
• Kukundikana kwemoyo kwakanyanya kana kuwedzera kwemazuva ano kwezviratidzo zvekukundikana kwemoyo
• Kuderera kwakanyanya kweropa (hypotension)
• Matambudziko akakomba echiropa
• Kuzvitakura kana kuyamwisa
• Zera riri pasi pemakore gumi nemasere

Chiremba wako achavawo akangwarira nezvekunyora ivabradine kana uine mamwe mamiriro anogona kukanganisa mushonga kana kuwedzera njodzi yako yezvinetso.

Mukuwedzera, mishonga yakati wandei inogona kukanganisa ivabradine, kunyanya avo vanokanganisa ma enzymes akafanana muchiropa chako anogadzirisa mushonga. Chiremba wako achaongorora mishonga yako yese iripo kuti ave nechokwadi chekuti hapana kukanganisa kunotyisa usati watanga ivabradine.

Mazita eIvabradine Brand

Ivabradine inowanikwa pasi pemazita akati wandei emhando, neCorlanor ndiyo zita rinowanzozivikanwa muUnited States. Mune dzimwe nyika, unogona kuiwana ichitengeswa pasi pemazita akaita seProcoralan, Coralan, kana mamwe mazita emhando yemunharaunda.

Zvisinei nezita remhando, mhando dzese dze ivabradine dzine chinhu chimwe chete chinoshanda uye zvinoshanda nenzira imwechete. Misiyano mikuru ingave muchitarisiko chepiritsi, simba rinowanikwa, kana zvinhu zvidiki zvisingashandi zvinoshandiswa mukugadzirwa.

Muzvitoro zvako zvemishonga zvinogona kutsiva mhando imwe neimwe zvichienderana nekuwanikwa kana inishuwarenzi. Izvi zvinowanzo chengeteka, asi kana ukaona chero shanduko mukuita kwako mushure mekutamisa mhando, zivisa chiremba wako. Vanogona kubatsira kuona kana shanduko iyi ichibatanidzwa nekugadzirwa kwakasiyana kana kana zvimwe zvinhu zvingave zvichibatanidzwa.

Zvimwe Zvinhu Zviri Panzvimbo ye Ivabradine

Kana ivabradine isina kukodzera iwe kana isingapi kutonga kwakakwana kwemoyo wako, mishonga yakati wandei inogona kubatsira kutarisira mamiriro ako. Chiremba wako achafunga nezve mamiriro ako chaiwo, mamwe mamiriro ehutano, uye zvinangwa zvekurapa pakusarudza sarudzo yakanakisa.

Beta-blockers vanowanzoita kurapwa kwekutanga kwekutonga kwemoyo uye vanosanganisira mishonga yakaita se metoprolol, carvedilol, uye bisoprolol. Mishonga iyi haingoderedzi chete kumhanya kwemoyo wako asiwo inoderedza ropa uye inogona kusimbisa kugona kwemoyo wako kupomba nekufamba kwenguva.

Calcium channel blockers, senge diltiazem kana verapamil, inomiririra imwe kirasi yemishonga inogona kuderedza kumhanya kwemoyo. Izvi zvinoshanda nekukanganisa kufamba kwe calcium mumasero ako emoyo, izvo zvinokanganisa kumhanya kwemoyo uye simba rekukanganisa.

Kune vanhu vane kukundikana kwemoyo, ACE inhibitors kana ARBs (angiotensin receptor blockers) zvinogona kushandiswa pamwe chete kana panzvimbo pe ivabradine. Mishonga iyi inobatsira moyo wako kushanda zvakanyanya nekuderedza basa uye nekuvandudza kuyerera kweropa.

Chiremba wako anogona zvakare kukurudzira kusanganiswa kwemishonga yakasiyana kuti uwane yakanakisa kutonga kwemoyo uchideredza mhedzisiro. Kiyi ndeyekuwana chiyero chakakodzera zvaunoda uye hutano hwako.

Ivabradine Ari Nani Kudarika Metoprolol Here?

Ivabradine na metoprolol zvese mishonga inobatsira kudzikisa kumhanya kwemoyo, asi anoshanda nenzira dzakasiyana uye ane zvakanakira zvakasiyana zvichienderana nemamiriro ako chaiwo. Panzvimbo peimwe iri nani kupfuura imwe, sarudzo inoenderana nezvido zvako zveutano uye kuti unotsungirira sei mushonga wega wega.

Metoprolol i beta-blocker iyo yanga ichishandiswa kwemakumi emakore uye ine tsvakurudzo yakawanda inotsigira kushandiswa kwayo mukukundikana kwemoyo uye mamwe mamiriro emoyo. Haisi kungononotsa kumhanya kwemoyo chete asiwo inoderedza ropa uye inogona kuvandudza basa remoyo nekufamba kwenguva. Zvisinei, vamwe vanhu vanowana kuneta, maoko netsoka anotonhora, kana matambudziko ekufema ne beta-blockers.

Ivabradine inopa mukana wega nekuti inonyanya kutarisisa kumhanya kwemoyo pasina kukanganisa zvakanyanya ropa kana kufema. Izvi zvinoita kuti ive yakakosha kune vanhu vanoda kudzora kumhanya kwemoyo asi vasingakwanise kutsungirira mhedzisiro yekudzikisa ropa ye beta-blockers, kana kune avo vatove vane ropa rakaderera.

Muzviitiko zvakawanda, vanachiremba vanoshandisa ivabradine na metoprolol pamwe chete panzvimbo yekusarudza imwe pane imwe. Iyi musanganiswa inogona kupa kudzora kumhanya kwemoyo kuri nani kupfuura mushonga wega wega uchiita kuti zvikwanise kushandisa madosi akaderera eimwe neimwe, zvichideredza mhedzisiro.

Chiremba wako achafunga nezvezvinhu zvakaita seropa rako, basa reitsvo, mamiriro ekufema, uye mamwe mishonga paachasarudza nzira yakanakira iwe. Sarudzo

Hongu, ivabradine inowanzova yakachengeteka kuvanhu vane chirwere cheshuga uye inogona kunyange kupa zvimwe zvakanakira pamusoro pemimwe mishonga yemoyo. Kusiyana nebeta-blockers, iyo inogona kuvhara zviratidzo zvekuchenjerera zve shuga yakaderera yeropa uye kuita kuti manejimendi echirwere cheshuga ave nematambudziko, ivabradine haipindiri mukukwanisa kwemuviri wako kuziva kana kupindura kuchinja kweshuga yeropa.

Vanhu vane chirwere cheshuga vanowanzoita njodzi huru yematambudziko emoyo, saka manejimendi emoyo anobudirira akakosha zvikuru. Ivabradine inogona kubatsira kuderedza kushushikana pamoyo wako pasina kunetsa manejimendi echirwere chako cheshuga. Zvisinei, chiremba wako achakutarisa zvakanyatsonaka, sezvo chirwere cheshuga chinogona kukanganisa maitiro emuviri wako ekugadzirisa mishonga.

Kana uine zvese chirwere cheshuga nematambudziko emoyo, ita shuwa kuti unozivisa vese vanokuchengeta nezve mishonga yako yese. Izvi zvinobatsira kuona kuti kurapwa kwako chirwere cheshuga nemishonga yemoyo zvinoshanda pamwe chete.

Ndingaita Sei Kana Ndakashandisa Ivabradine Yakawandisa Netsaona?

Kana netsaona ukatora ivabradine yakawandisa, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira, kunyangwe ukaita zvakanaka. Kutora zvakawandisa kunogona kukonzera kuti chiyero chemoyo wako chiderere zvakanyanya, izvo zvinogona kuva zvakakomba uye zvinoda kutariswa kwekurapa.

Zviratidzo zvaungave wakatora zvakawandisa zvinosanganisira kunzwa uchidzungaira zvikuru, uchinzwa kusimba mumusoro, kana kupera simba, uchinzwa chiyero chemoyo chinononoka zvisingawanzo, kana kuva nematambudziko ekufema. Kana uine chero zviratidzo izvi, tsvaga rubatsiro rwekurapa nekukasira.

Paunenge uchimirira rubatsiro rwekurapa, edza kugara wakadzikama uye gara kana kurara munzvimbo yakasununguka. Usaedze kuzviita kurutsa kunze kwekunge wakanzi zvakananga nachiremba. Chengeta bhodhoro remishonga newe kuti uratidze vashandi vezvokurapa zvakanyatsojeka zvawakatora uye zvakawanda sei.

Kuti mudzivise kuwedzera mishonga netsaona, funga kushandisa chirongwa chemishonga kana kumisa zviyeuchidzo zvefoni yechirongwa chako chemishonga. Izvi zvinogona kukubatsira kuchengeta rekodhi rekuti wakatotora here muyero wako wezuva.

Ndingaita Sei Kana Ndakarasikirwa neDose yeIvabradine?

Kana ukarasikirwa nedose yeivabradine, itore pakarepo paunorangarira, asi chete kana zvave pasi pe6 maawa kubva panguva yako yakarongwa yekutora mishonga. Kana zvave kwenguva refu kupfuura maawa matanhatu, kana kana yava nguva yekutora dose yako inotevera, siya dose yakarasika uye uenderere mberi nechirongwa chako chetsika.

Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yakarasika. Izvi zvinogona kukonzera kuti kurova kwemoyo wako kudzikire zvakanyanya, izvo zvinogona kuva nenjodzi. Zviri nani kukanganwa dose imwe pane kuisa njodzi yekutora mishonga yakawandisa kamwechete.

Kana iwe uchikanganwa madosi kazhinji, taura nachiremba wako nezve nzira dzekukubatsira kurangarira. Vanogona kukurudzira kumisa maalarm efoni, kushandisa chirongwa chemishonga, kana kutora mishonga yako panguva imwe chete nebasa rezuva nezuva rakaita semadyiro.

Kukanganwa dose dzimwe nguva kazhinji hakuna njodzi, asi edza kutora ivabradine nguva dzose sezvakanyorwa. Kudzora nguva dzose kunobatsira kuchengetedza mazinga akagadzikana emishonga mumuviri wako, izvo zvinopa kutonga kwakanyanya kwekurova kwemoyo.

Ndingamira Rini Kutora Ivabradine?

Unofanira kungomira kutora ivabradine pasi pekutungamirirwa nekutarisa kwachiremba wako. Kunyangwe kana uchinzwa zviri nani, kumira kamwechete kunogona kukonzera kuti kurova kwemoyo wako kuwedzere nekukurumidza, izvo zvinogona kuwedzera zviratidzo zvako kana kuisa kushushikana pamoyo wako.

Chiremba wako anowanzo kuda kuderedza zvishoma nezvishoma dose yako pane kumira zvachose. Iyi nzira, inonzi tapering, inobvumira moyo wako kuti ugadzirise zvishoma nezvishoma kuchinja kwemishonga uye inoderedza njodzi yemigumisiro yekudzoka.

Sarudzo yekumisa ivabradine inoenderana nezvinhu zvakati wandei, kusanganisira kuti mamiriro emoyo wako anogadziriswa sei, kana uri kutora mamwe mishonga yemoyo, uye hutano hwako hwese. Vamwe vanhu vangada kuitora kwenguva refu, nepo vamwe vachikwanisa kumisa kana mamiriro avo akavandudzika zvakanyanya.

Kugara uchienda kunoona chiremba wako kunokosha kuti uzive kuti ungachinja kana kumisa sei mishonga yako zvakachengeteka. Vachatarisa kumhanya kwemoyo wako, zviratidzo, uye kushanda kwemoyo wako kuti vaite sarudzo yakanakisa yehutano hwako.

Ndingaita Maekisesa Ndiri Kutora Ivabradine Here?

Hongu, unogona kuita maekisesa uchitora ivabradine, uye kutaura zvazviri, chiitiko chemuviri chakakodzera chinowanzo kurudzirwa sechikamu chechirongwa chako chehutano hwemoyo hwese. Zvisinei, mushonga uyu uchakanganisa maitiro emoyo wako kumaitiro emaekisesa, saka uchada kugadzirisa zvaunotarisira uye nzira yako.

Sezvo ivabradine ichideredza kumhanya kwemoyo wako paunenge uchizorora, kumhanya kwemoyo wako panguva yemaekisesa kuchavawo kwakaderera kupfuura zvaive zvisati zvaitwa mushonga. Izvi zvinoreva kuti haugone kuvimba nezvinangwa zvechinyakare zvekumhanya kwemoyo panguva yemaekisesa. Panzvimbo pezvo, tarisa kuti unonzwa sei panguva yebasa - unofanirwa kukwanisa kuenderera mberi nekukurukurirana panguva yemaekisesa epakati.

Tangisa chero chirongwa chitsva chemaekisesa zvishoma nezvishoma uye teerera kuti muviri wako unopindura sei. Kana ukaona kufema kwakanyanya, kurwadziwa muchipfuva, dzungu, kana kuneta zvakanyanya panguva yemaekisesa, rega basa racho uye bvunza chiremba wako.

Mupi wako wehutano anogona kukubatsira kugadzira chirongwa chakakodzera chemaekisesa chinofunga nezve mamiriro emoyo wako, nhanho yako yekukodzera yazvino, uye mhedzisiro yeivabradine. Vanogona kukurudzira kushanda nechirongwa chekugadzirisa moyo kana uine moyo usina simba kana mamwe matambudziko makuru emoyo.