Chii chinonzi Lapatinib: Zvayakashandiswa, Mishonga, Matambudziko, nezvimwe

Lapatinib mushonga wekenza unovavarira kubatsira kunonotsa kukura kwemarudzi akati wandei emasero ekenza yemazamu. Iyo ndeyeboka remishonga inonzi tyrosine kinase inhibitors, iyo inoshanda nekudzivisa mapuroteni akati wandei anobatsira masero ekenza kukura nekupararira mumuviri wako.

Mushonga uyu unonyanya kushandiswa pamwe chete nemamwe marapirwo ekenza kubatsira varwere vane kenza yemazamu yakakura kana metastatic. Kunzwisisa kuti lapatinib inoshanda sei uye zvekutarisira zvinogona kukubatsira kuti unzwe wakagadzirira uye wakavimbika nezvekufamba kwako kwekurapa.

Chii chinonzi Lapatinib?

Lapatinib mushonga wekenza wemuromo unonyanya kuvavarira masero ekenza ane mamwe mapuroteni receptors. Inoshanda nekudzivisa mapuroteni maviri akakosha anonzi HER2 uye EGFR anobatsira masero ekenza kukura nekukwidziridza.

Nzira iyi yakatarwa zvinoreva kuti lapatinib inotarisa kumisa masero ekenza apo ichikonzera kukuvara kushoma kumasero ane hutano kana ichienzaniswa nechemotherapy yechinyakare. Mushonga uyu unouya muchimiro chepiritsi, zvichiita kuti zvive nyore kutora kumba sechikamu chetsika yako yezuva nezuva.

Chiremba wako achasarudza kana lapatinib yakakunakira zvichienderana nezvinhu zvakasiyana zvemasero ako ekenza. Iyi nzira yakagadzirirwa munhu mumwe nemumwe inobatsira kuona kuti unogamuchira kurapwa kunoshanda zvakanyanya kune mamiriro ako chaiwo.

Chii chinonzi Lapatinib chinoshandiswa?

Lapatinib inonyanya kushandiswa kurapa kenza yemazamu yakakura kana metastatic ine mamwe mapuroteni markers anonzi HER2-positive. Inowanzo kurairwa kana kenza yapararira kune dzimwe nhengo dzemuviri wako kana kana mamwe marapirwo asina kubudirira.

Mushonga uyu unowanzo sanganiswa nemamwe madhiragi ekenza se capecitabine kana letrozole kugadzira nzira yakazara yekurapa. Iyi kurapa kwakabatanidzwa kunogona kubatsira kunonotsa kufambira mberi kwekenza uye kunogona kubatsira kudzikisa tumor mune vamwe varwere.

Chiremba wako wezve oncology angakurudzira lapatinib kana wakambogamuchira kurapwa ne trastuzumab (Herceptin) uye chemotherapy yakavakirwa pa anthracycline. Izvi zvinoita kuti lapatinib ive sarudzo yakakosha kune varwere vanoda mamwe marapirwo.

Lapatinib Inoshanda Sei?

Lapatinib inoshanda nekudzivisa mapuroteni maviri chaiwo pamaseru ekenza anonzi HER2 uye EGFR receptors. Mapuroteni aya anowanzo tumira zviratidzo zvinoudza maseru ekenza kukura nekukurumidza.

Nekudzivisa zviratidzo izvi, lapatinib inonyatsoisa mabhureki pakukura kweseru rekenza. Funga nezvazvo sekugura mitsara yekutaurirana iyo maseru ekenza anoshandisa kuronga kukura kwavo nekupararira mumuviri wako.

Mishonga iyi inoonekwa sekurapa kenza kwakasimba zvine mwero uye kazhinji inononoka kupfuura chemotherapy yechinyakare. Kunyangwe ichishanda pakunangana nemaseru ekenza, inowanzoita kuti pave nemigumisiro mishoma yakakomba kupfuura mamwe mishonga yekenza.

Ndinofanira Kutora Sei Lapatinib?

Tora lapatinib sezvinorayirwa nachiremba wako, kazhinji kamwe chete pazuva panguva imwe chete zuva rega rega. Madosi anowanzoitika mapiritsi mashanu (1,250 mg mune zvese) akatorwa pamwechete, kunyangwe chiremba wako angachinja izvi zvichienderana nezvido zvako.

Unofanira kutora lapatinib mudumbu risina chinhu, angangoita awa rimwe usati wadyisa kana angangoita awa rimwe mushure mekudya. Izvi zvinobatsira muviri wako kutora mushonga zvakanaka uye unoona kuti unoshanda zvakanaka sezvinobvira.

Medza mapiritsi ese negirazi remvura izere. Usapwanye, kutsenga, kana kuputsa mapiritsi, sezvo izvi zvinogona kukanganisa maitiro emuviri wako emushonga. Kana uine dambudziko rekumedza mapiritsi, taura nechikwata chako chehutano nezve nzira dzinogona kubatsira.

Edza kutora mushonga wako panguva imwe chete zuva rega rega kubatsira kuchengetedza mazinga akagadzikana mumuviri wako. Varwere vazhinji vanozviwana zvichibatsira kumisa chiyeuchidzo chezuva nezuva kana kuisa mukati memararamiro avo emangwanani kana manheru.

Ndinofanira Kutora Lapatinib Kwenguva Yakareba Sei?

Kureba kwemushonga we lapatinib kunosiyana zvakanyanya kubva kumunhu nemunhu, zvichienderana nekuti kenza yako inopindura sei uye kuti unotsungirira sei mushonga. Vamwe varwere vanogona kuutora kwemwedzi yakati wandei, asi vamwe vanogona kuenderera mberi kwegore kana kupfuura.

Oncologist wako achatarisa kufambira mberi kwako kuburikidza nekutarisa nguva dzose, bvunzo dzeropa, uye imaging scans. Aya maapointments anobatsira kuziva kana mushonga uri kushanda nemazvo uye kana uri kusangana nemhedzisiro yechero inonetsa.

Usambofa wakamira kutora lapatinib kamwechete usina kuzvikurukura nachiremba wako kutanga. Kunyangwe kana uchinzwa zvakanaka, kumira kamwechete kunogona kubvumira maseru ekenza kutanga kukura zvakare. Chikwata chako chehutano chichakutungamira kuburikidza nechero shanduko kuronga kwako kurapwa.

Ndezvipi Zvinhu Zvinokonzerwa neLapatinib?

Kufanana nemishonga yese yekenza, lapatinib inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anozviwana. Mazhinji emhedzisiro anogona kutariswa nekuchengetwa kwakakodzera uye kutaurirana nechikwata chako chehutano.

Heano mhedzisiro yakajairika yaungasangana nayo paunenge uchitora lapatinib:

• Manyoka (anokanganisa varwere vazhinji asi anowanzo kutariswa)
• Meno ganda kana ganda rakaoma pamaoko netsoka
• Kuneta kana kunzwa kuneta kupfuura zvakajairika
• Nausea kana dumbu rinogumbuka
• Kurasikirwa nechido
• Maronda emuromo kana shanduko mukuravira

Izvi zvinowanzoitika zvinokonzeresa zvinowanzoita nani sezvo muviri wako uchigadzirisa kumushonga. Chikwata chako chehutano chinogona kupa nzira dzakatarwa dzekubatsira kutarisira chimwe nechimwe chezviratidzo izvi nemazvo.

Vamwe varwere vanogona kusangana nemhedzisiro yakakomba inoda kutariswa kwekurapa nekukurumidza:

• Manyoka akakomba asingavanduki nemishonga
• Zviratidzo zvematambudziko echiropa (kuchena kweganda kana maziso, weti yakasviba)
• Matambudziko emoyo (kufema kusina kujairika, kurwadziwa muchipfuva)
• Kuita kweganda kwakakomba kana kuputika kwakanyanya
• Matambudziko emapapu (kukosora kusingaperi, kufema kwakaoma)

Bata chikwata chako chehutano nekukurumidza kana ukaona chero zviratidzo zvakakomba izvi. Kukurukurirana nekukurumidza kunobatsira kuona kuti chero matambudziko anogadziriswa nekukurumidza uye zvakachengeteka.

Mhedzisiro isingawanzoitiki asi yakakomba

Kunyange zvazvisingawanzoitiki, vamwe varwere vanogona kusangana nemhedzisiro isingawanzoitiki asi inogona kuva yakakomba iyo inoda kutariswa zvakanyanya:

• Matambudziko emoyo akakomba anosanganisira kudzikira kwebasa remoyo
• Kukuvadzwa kwakakomba kwechiropa kunogona kuva kunotyisa upenyu
• Kuzvimba kwakakomba kwemapapu (pneumonitis)
• Kuita kweganda kwakakomba kunogona kutungamirira kukuvadzwa
• Kusagadzikana kwakakomba kweelectrolyte kubva kumanyoka akareba

Chiremba wako achakutarisa zvakanyanya kuti uone matambudziko aya asingawanzoitiki kuburikidza nekuongororwa kweropa nguva dzose uye kuongororwa kwebasa remoyo. Kuona nekukurumidza uye kurapwa kwenyaya idzi kunogona kudzivirira kuti dzive dzakakomba.

Ndiani Asingafaniri Kutora Lapatinib?

Lapatinib haina kukodzera munhu wese, uye chiremba wako achanyatsoongorora kana zvakachengeteka kwauri. Mamwe mamiriro ehutano kana mamiriro anogona kuita kuti mushonga uyu uve nenjodzi kushandisa.

Haufaniri kutora lapatinib kana iwe uchiziva kuti une allergy kumushonga kana chero zvinhu zvawo. Uyezve, kana uine chirwere chechiropa chakakomba kana matambudziko makuru emoyo, chiremba wako anogona kukurudzira mamwe marapirwo.

Vakadzi vane pamuviri kana kuyamwisa havafaniri kutora lapatinib, sezvo inogona kukuvadza vacheche vari kukura. Kana uri wezera rekubereka vana, uchada kushandisa nzira yekudzivirira kubata pamuviri inoshanda panguva yekurapa uye kwenguva yakati rebei mushure mekumisa mushonga.

Chiremba wako achavawo akangwarira pakuraira lapatinib kana uine nhoroondo yechirwere chemoyo, matambudziko echiropa, kana chirwere chemapapu. Mamiriro aya anoda kunyatsoongororwa uye anogona kukanganisa hurongwa hwako hwekurapa.

Mazita eBrand eLapatinib

Zita rebrand re lapatinib ndiTykerb muUnited States nenyika dzakawanda. Dzimwe nzvimbo dzinogona kuziva nezita rebrand Tyverb, kunyangwe ese ari maviri aine chinhu chimwe chete chinoshanda.

Mhando dzakajairika dze lapatinib dziri kuwanikwa mune dzimwe nyika, izvo zvinogona kupa mari yekuchengetedza uku vachipa mabhenefiti akafanana ekurapa. Pharmacy yako kana timu yehutano inogona kukubatsira kunzwisisa kuti ndeipi vhezheni iripo munzvimbo yako.

Zvisinei nezita rebrand, ese mavhezheni e lapatinib ane mushonga mumwe chete unoshanda uye anoshanda nenzira imwechete. Chiremba wako achanyora vhezheni yakakodzera uye inowanikwa kune mamiriro ako ezvinhu.

Zvimwe Zvinhu Zviri Kutsiva Lapatinib

Mishonga yakati wandei inowanikwa yekurapa kenza yemazamu yeHER2-positive, zvichienderana nemamiriro ako chaiwo uye nhoroondo yekurapa. Zvimwe zvinhu izvi zvinoshanda kuburikidza nemaitiro akasiyana asi zvinovavarira kuzadzisa zvinangwa zvakafanana.

Trastuzumab (Herceptin) inowanzo shandiswa seyekutanga-mutsara wekurapa kenza yemazamu yeHER2-positive. Zvimwe zvingasarudzwa zvinosanganisira pertuzumab (Perjeta), T-DM1 (Kadcyla), uye mishonga mitsva senge tucatinib (Tukysa) kana neratinib (Nerlynx).

Oncologist wako achafunga nezvezvinhu zvakaita sekurapa kwako kwapfuura, mamiriro ako ehutano azvino, uye hunhu chaihwo hwekenza paunenge uchikurudzira dzimwe nzira. Mushonga wega wega une mabhenefiti awo uye mhedzisiro inogona kuitika iyo inoda kuyerwa zvakanyatso.

Sarudzo yekurapa yakanyanya kuita munhu mumwechete, uye zvinoshanda zvakanyanya kune mumwe munhu zvingasava sarudzo yakanaka kune mumwe. Vimba nechikwata chako chehutano kuti chikutungamirire kune sarudzo yakakodzera yemamiriro ako akasiyana.

Lapatinib iri Nani Pane Trastuzumab?

Lapatinib na trastuzumab vanoshanda zvakasiyana uye vanowanzo shandiswa panguva dzakasiyana dzekurapa, zvichiita kuti kuenzanisa kwakananga kuve kwakaoma. Zvese zviri zviviri mishonga inoshanda yeHER2-positive cancer yemazamu, asi imwe neimwe ine zvainobatsira zvakasiyana.

Trastuzumab inowanzo shandiswa seyekutanga-mutsetse wekurapa uye inogona kupihwa intravenously, nepo lapatinib inowanzo chengeterwa kurapa kwemumwe mutsetse uye inouya semushonga wemuromo. Lapatinib inogona kunge iri nyore kune varwere vane cancer yakapararira kuuropi, sezvo ichikwanisa kuyambuka chipingamupinyi cheropa-uropi zvakanyanya.

Vamwe varwere vanogona kubatsirwa nekugamuchira mishonga yese iri mukuenzana kana pamwe chete. Chiremba wako weoncologist achasarudza nzira yakanakisa zvichienderana nemaitiro ekenza yako, nhoroondo yako yekurapa, uye hutano hwako hwese.

Pane kufunga imwe se

Kana ukatora lapatinib yakawanda kupfuura yakanyorerwa netsaona, fonera chiremba wako kana nzvimbo yekudzora muchetura nekukasika. Kutora yakawanda kunogona kuwedzera njodzi yako yezvinhu zvinokuvadza, kunyanya matambudziko emoyo uye manyoka akanyanya.

Usamirira kuti uone kana uchinzwa zviratidzo usati watsvaga rubatsiro. Kunyangwe ukaita zvakanaka pakutanga, overdose inogona kukonzera mhedzisiro yakareba inoda kutariswa kwekurapa. Chengeta bhodhoro remushonga newe paunofona kuti uwane rubatsiro.

Kuti udzivise overdoses netsaona, shandisa chirongwa chemapiritsi kana kumisa zviyeuchidzo pafoni yako. Usambofa wakawedzera madosi kana ukakanganwa imwe, sezvo izvi zvinogona kukonzera kutora mushonga wakawanda kamwechete.

Ndingaita Sei Kana Ndikakanganwa Dose yeLapatinib?

Kana ukakanganwa dose ye lapatinib, itore paunorangarira, asi chete kana zvapfuura maawa gumi nemaviri kubva panguva yako yakarongwa. Kana maawa anopfuura gumi nemaviri apfuura, siya dose yakakanganwa uye tora dose yako inotevera panguva yakajairika.

Usambofa wakatora madosi maviri kamwechete kuti ugadzirise dose yakakanganwa, sezvo izvi zvinogona kuwedzera njodzi yako yezvinhu zvinokuvadza. Panzvimbo pezvo, ramba uchiita chirongwa chako chekushandisa mushonga uye zivisa timu yako yehutano nezve chero madosi akakanganwa.

Funga kumisa zviyeuchidzo zvemazuva ese pafoni yako kana kushandisa chirongwa chemapiritsi kuti zvikubatsire kurangarira mushonga wako. Kuenderana mukutora lapatinib kunobatsira kuchengetedza mazinga akagadzikana muropa rako kuti uwane kushanda zvakanaka.

Ndingamira Rini Kutora Lapatinib?

Unofanirwa kungomira kutora lapatinib pasi pekutungamirirwa kwechiremba wako weoncologist, kunyangwe uchinzwa zvakanaka kana uchiona zvinhu zvinokuvadza. Kumira nekukurumidza kunogona kubvumira maseru ekenza kutanga kukura zvakare.

Chiremba wako achasarudza kuti zvakachengeteka rini kumira zvichienderana nekuti mushonga uri kushanda sei, zvinhu zvinokuvadza, uye hutano hwako hwese. Sarudzo iyi inosanganisira kufunga zvakanyanya kwezvinhu zvakawanda zvakakosha kumamiriro ako ezvinhu.

Kana matambudziko emigumisiro akava akaoma kubata, taura nechikwata chako chekuchengetedza hutano nezvekugadzirisa muyero kana matanho ekutsigira usati wafunga kumisa mushonga. Migumisiro yakawanda inogona kubatwa zvakanaka nekuchengetedzwa kwakakodzera.

Ndinganwe Doro Ndiri Kutora Lapatinib Here?

Kunyange hazvo pasina kurambidzwa kwakajeka pamusoro pedoro ne lapatinib, zvinowanzoitwa kudzora kana kudzivisa doro panguva yekurapa kenza. Doro rinogona kukonzera kuwedzera kwemimwe migumisiro uye rinogona kukanganisa kugona kwemuviri wako kugadzirisa mushonga.

Sezvo lapatinib inogona kukanganisa basa rechiropa, kuwedzera doro kunogona kuisa kushushikana kwakawanda pachiropa chako. Kana ukasarudza kunwa dzimwe nguva, kurukura izvi nechikwata chako chekuchengetedza hutano kuti unzwisise zvingave zvakachengeteka mumamiriro ako chaiwo.

Tarisa pakuramba wakanyatsogadzirwa nemvura nemamwe zvinwiwa zvine hutano panguva yekurapa. Muviri wako unoda chikafu chakakwana uye hydration kuti ubatsire kubata migumisiro yekurapa uye kutsigira hutano hwako hwese.