Chii chinonzi Lasmiditan: Zvinoshandiswa, Mishonga, Zvakaipa uye Zvimwe

Lasmiditan mushonga mutsva wemishonga wakagadzirirwa kurapa migraine headaches muvanhu vakuru. Iyo ndeyeboka remishonga inonzi selective serotonin receptor agonists, iyo inoshanda zvakasiyana nemishonga yechinyakare ye migraine nekunangana nemamwe ma receptors ehuropi anobatanidzwa mukurwadziwa kwe migraine.

Mushonga uyu unopa tariro kune vanhu vasina kuwana zororo nekune dzimwe nzira dzekurapa migraine kana avo vasingakwanise kutora mamwe mishonga ye migraine nekuda kwemamiriro emoyo. Kunzwisisa kuti lasmiditan inoshanda sei uye zvekutarisira zvinogona kukubatsira kuita sarudzo dzine ruzivo nezve kutarisirwa kwako kwe migraine.

Chii chinonzi Lasmiditan?

Lasmiditan mushonga wemishonga unorapa acute migraine attacks ine kana isina aura muvanhu vakuru. Kusiyana nemamwe mishonga yekare ye migraine, haina kukanganisa midzi yeropa mumoyo mako, zvichiita kuti ive sarudzo yakachengeteka kune vanhu vane mamwe mamiriro emwoyo.

Mishonga inoshanda nekumisa mamwe ma serotonin receptors muuropi hwako anonzi 5-HT1F receptors. Aya ma receptors anotamba basa rakakosha mumigraine pain pathways. Kana lasmiditan ikasunga kune aya ma receptors, inobatsira kuderedza kuzvimba uye kurwadziwa zviratidzo zvinogadzira migraine yako zviratidzo.

Unogona kuziva lasmiditan nezita rayo remhando, Reyvow. Yakabvumidzwa neFDA muna 2019 semushonga wekutanga muboka rayo, ichimiririra kufambira mberi kukuru mukurapa migraine sarudzo.

Chii chinonzi Lasmiditan chinoshandiswa?

Lasmiditan inonyanya kushandiswa kurapa acute migraine attacks muvanhu vakuru. Izvi zvinoreva kuti yakagadzirirwa kumisa migraine yatotanga, pane kudzivirira ramangwana migraines kubva kuitika.

Chiremba wako angangokurudzira lasmiditan kana iwe uchiona moderate kusvika kune yakanyanya migraine headaches inokanganisa mabasa ako ezuva nezuva. Inogona kubatsira nekunetsa kwemusoro, kusvotwa, uye kunzwisiswa kune chiedza uye ruzha izvo zvinowanzoenda nemigraines.

Mishonga iyi inokosha zvikuru kuvanhu vane chirwere chemoyo, ropa rakakwira, kana mamwe mamiriro emoyo nemidziyo yeropa anoita kuti mishonga yechinyakare ye triptan isachengeteke. Iri zvakare sarudzo kana wakaedza mamwe marapirwo e migraine pasina kubudirira kana kusangana nemigumisiro inonetsa.

Lasmiditan Inoshanda Sei?

Lasmiditan inoshanda nekunangana nemamwe ma serotonin receptors muuropi hwako anonzi 5-HT1F receptors. Kana migraine yatanga, nzira dzinorwadza dzinova dzakanyanya kushanda, dzichitumira zviratidzo zvinorwadza zvakanyanya mumusoro mako uye zvichikonzera zvimwe zviratidzo zvakaita senausea.

Nekubatanidza kune aya ma receptors, lasmiditan inobatsira kudzikamisa nzira dze nerve dzakanyanya kushanda dzinogadzira kurwadziwa kwemigraine. Inoderedzawo kuzvimba munyama yeuropi inobatsira kuzviratidzo zvemigraine. Iyi nzira yakatarwa inobatsira kukanganisa maitiro e migraine kana yatanga.

Mishonga iyi inoonekwa seyepakati pesimba uye inowanzo tanga kushanda mukati memaawa maviri ekui tora. Kusiyana nemamwe mishonga ye migraine inoderedza midziyo yeropa, lasmiditan haiite zvakanyanya kune yako cardiovascular system, zvichiita kuti ive yakachengeteka kune vanhu vane mamiriro emoyo.

Ndinofanira Kutora Sei Lasmiditan?

Tora lasmiditan sezvakanyorwa nachiremba wako, kazhinji semushonga mumwe chete paunonzwa migraine ichitanga. Unogona kuitora uine chikafu kana usina, kunyangwe kuitora nechikafu kungabatsira kuderedza dumbu kana uine nausea.

Medza piritsi rose negirazi remvura izere. Usapwanye, kuputsa, kana kutsenga piritsi, sezvo izvi zvinogona kukanganisa nzira iyo mishonga inotorwa nayo. Mushonga unowanzo tanga ndeye 50mg, kunyangwe chiremba wako anganyora 100mg kana zvichidikanwa.

Zvakakosha kutora lasmiditan paunenge uchiziva zviratidzo zvemigraine zvichitanga. Mushonga unoshanda zvakanyanya kana watorwa pakutanga kwemigraine, vasati marwadzo ava akakomba. Kana migraine yako isingavandudzi mushure memaawa maviri, usatore mushonga wechipiri usati wataurirana nachiremba wako kutanga.

Ndingatora Lasmiditan Kwenguva Yakareba Sei?

Lasmiditan yakagadzirirwa kushandiswa kwenguva pfupi kurapa kurwisa kwemigraine, kwete kudzivirira zuva nezuva kwenguva refu. Unofanira kungoitora chete paunenge uchinzwa migraine chaiyo, kwete sechiyero chekudzivirira.

Mushonga unowanzoita kuti munhu anzwe zviri nani mukati memaawa maviri, uye mhedzisiro yawo inogona kugara kusvika maawa makumi maviri nemana. Hauzofaniri kutora mushonga unopfuura mumwe mukati menguva yeawa makumi maviri nemana kunze kwekunge wakanzi na chiremba wako. Kuitora kakawanda kunogona kukonzera kurwadziwa kwemusoro nekuda kwekushandisa mishonga zvakanyanya.

Kana ukawana uchida lasmiditan mazuva anopfuura gumi pamwedzi, taura nachiremba wako nezvekurapa kudzivirira migraine. Kushandiswa kakawanda kwemishonga yekuita migraine inogona dzimwe nguva kuita kuti kurwadziwa kwemusoro kuwedzere nekufamba kwenguva, saka zvakakosha kuishandisa sezvakarairwa.

Ndezvipi Zvakaipa ZveLasmiditan?

Semishonga yese, lasmiditan inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese achizviona. Mhedzisiro yakajairika inowanzoita nyoro uye yenguva pfupi, ichigadzirisa mushonga uchibuda mumuviri wako.

Heano mhedzisiro inonyanya kuziviswa yaungangove nayo:

• Kutenderera kana kunzwa uchinetseka
• Kuzara kana kuneta
• Nausea kana kusagadzikana mudumbu
• Kushaya simba kwemhasuru kana kunzwa kusagadzikana
• Kutinhira kana kupera nhengo mumaoko kana tsoka
• Muromo wakaoma
• Kunzwa usina kubatana kana

  Mhedzisiro iyi inowanzoita nani mukati meawa shoma sezvo muviri wako uchigadzirisa mushonga. Kudzungaira uye kurara kunogona kuoneka zvakanyanya, ndosaka usingafaniri kutyaira kana kushandisa michina kwemaawa masere mushure mekutora lasmiditan.

  Mhedzisiro isingawanzoitiki asi yakakomba inoda kutariswa kwekurapa nekukurumidza inosanganisira:

  • Kudzungaira kwakanyanya kana kufenda
  • Kutadza kufema kana kusungirirwa pachipfuva
  • Kushaya simba kwemhasuru kwakanyanya
  • Kuvhiringidzika kana kusanzwisisa
  • Maitiro ekugadzirisa muviri kune zvinhu zvitsva akadai serashi, kukwenya, kana kuzvimba

  Kana ukaona chero mhedzisiro yakakomba iyi, taura nemupi wako wehutano nekukurumidza kana kutsvaga rubatsiro rwekurapa rwechimbichimbi. Kunyangwe zvisingawanzoitiki, zviratidzo izvi zvinogona kuratidza maitiro akakomba anoda kurapwa nekukurumidza.

  Ndiani Asingafaniri Kutora Lasmiditan?

  Lasmiditan haina kukodzera munhu wese, uye mamiriro ezvinhu kana mamiriro ezvinhu anoita kuti isashandiswe. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa usati wanyora mushonga uyu.

  Haufaniri kutora lasmiditan kana uine chirwere chechiropa chakakomba, sezvo muviri wako ungasaite kugadzirisa mushonga nemazvo. Vanhu vane nhoroondo yekurohwa, kurwisa kwemoyo, kana mamwe mamiriro akakomba emoyo nemitsipa vanofanirwawo kudzivisa mushonga uyu.

  Heano mamiriro makuru uye mamiriro apo lasmiditan isingakurudzirwi:

  • Chirwere chechiropa chakakomba kana kutadza kwechiropa
  • Kurohwa kwakapfuura kana transient ischemic attack (TIA)
  • Nhoroondo yekurwisa kwemoyo kana matambudziko akakomba emoyo
  • Kuvhunduka kweropa rakakwira
  • Kuzvitakura kana kuyamwisa
  • Zera riri pasi pemakore gumi nemasere
  • Allergies inozivikanwa kune lasmiditan kana zvinosanganiswa zvayo

  Uyezve, unofanira kungwarira kana uine matambudziko eitsvo, uchitora mamwe maantidepressants, kana uine nhoroondo yekushandisa zvinodhaka zvisina kufanira. Mhedzisiro yekunyaradza ye lasmiditan inogona kuwedzerwa nedoro kana mamwe ma depressants e central nervous system, saka dzivisa kusanganiswa uku.

Zita reBrand reLasmiditan

Lasmiditan inotengeswa pasi pezita rebrand Reyvow muUnited States. Iri mushonga wezita rebrand rinogadzirwa naEli Lilly and Company uye rakatanga kubvumidzwa neFDA muna Gumiguru 2019.

Reyvow inowanikwa mumhando mbiri: 50mg uye 100mg mahwendefa. Mhando dzese dzine chinhu chimwe chete chinoshanda, lasmiditan, asi mumari dzakasiyana kuitira kuti uwedzere dosing yakavakirwa pazvido zvako uye mhinduro yekurapa.

Parizvino, hapana generic vhezheni dze lasmiditan dziripo, sezvo mushonga uchiri pasi pekudzivirirwa kwepatent. Izvi zvinoreva kuti Reyvow ndiyo chete mhando iripo, iyo inogona kuiita inodhura kupfuura mishonga yekare ye migraine ine generic imwe nzira.

Lasmiditan Zvimwe Zvinhu

Kana lasmiditan isina kukodzera iwe kana isingapi rubatsiro rwakakwana, dzimwe nzira dzekurapa migraine dziripo. Chiremba wako anogona kukubatsira kuwana imwe nzira yakanakisa zvichienderana nenhoroondo yako yezvokurapa uye zvaunoda.

Mishonga yechinyakare ye triptan yakaita se sumatriptan (Imitrex), rizatriptan (Maxalt), uye zolmitriptan (Zomig) inowanzoedzwa kutanga. Mishonga iyi inoshanda nekudzikisa tsinga dzeropa muuropi uye inoshanda kune vanhu vazhinji, kunyangwe isina kukodzera avo vane matambudziko emoyo.

Heano mapoka makuru emimwe nzira yekurapa migraine:

• Triptans (sumatriptan, rizatriptan, eletriptan)
• CGRP receptor antagonists (ubrogepant, rimegepant)
• Ergot alkaloids (dihydroergotamine)
• Anti-nausea mishonga (metoclopramide, ondansetron)
• Pain relievers (ibuprofen, naproxen, acetaminophen)
• Combination mishonga (sumatriptanaproxen)

Sarudzo itsva dzakadai se ubrogepant (Ubrelvy) uye rimegepant (Nurtec ODT) dzinoshanda zvakafanana ne lasmiditan nekunangana nemamwe ma receptors anobatanidzwa mukurwadziwa kwemigraine. Aya ma CGRP antagonists anogona kuva dzimwe nzira dzakanaka kana usingakwanise kutora lasmiditan asi uchida sarudzo yakachengeteka yemwoyo.

Ko Lasmiditan Ari Nani Pane Sumatriptan?

Zvese lasmiditan ne sumatriptan zvinoshanda kurapa migraine, asi zvinoshanda zvakasiyana uye zvine zvakanakira zvakasiyana zvichienderana nemamiriro ako ega. Hapana imwe iri yakanaka kupfuura imwe, sezvo sarudzo yakanaka ichienderana neprofile yako chaiyo yekurapa uye mhinduro kumushonga.

Sumatriptan yanga iripo kwenguva refu uye ine tsvagiridzo yakawanda inotsigira kushanda kwayo. Inowanzoedzwa kutanga nekuti inowanikwa mumhando dzakawanda (mapiritsi, majekiseni, nasal spray) uye ine generic versions dzinoita kuti ive yakachipa. Zvisinei, sumatriptan inogona kuderedza midzi yeropa, zvichiita kuti isakodzere vanhu vane matambudziko emwoyo.

Chinhu chikuru chinobatsira lasmiditan ndiyo profile yayo yekuchengeteka yevanhu vane matambudziko emwoyo. Haina kukanganisa midzi yeropa mumoyo, zvichiita kuti ive sarudzo yakachengeteka kana uine chirwere chemwoyo, high blood pressure, kana mamwe njodzi dzemwoyo. Inogonawo kukonzera kushoma kwemusoro wemusoro kana ichishandiswa kazhinji.

Sarudzo pakati pemishonga iyi inowanzouya pasi peprofile yako chaiyo yehutano. Kana uine matambudziko emwoyo, lasmiditan inogona kuva sarudzo iri nani. Kana usina matambudziko emwoyo uye mutengo chinhu, sumatriptan inogona kuva inoshanda.

Mibvunzo Inowanzo Bvunzwa Pamusoro peLasmiditan

Ko Lasmiditan Yakachengeteka Kune Vanhu Vane Chirwere Chemwoyo?

Hongu, lasmiditan inowanzoonekwa seyakachengeteka kune vanhu vane chirwere chemwoyo ichienzaniswa nemishonga yechinyakare ye migraine yakaita setriptans. Kusiyana ne triptans, lasmiditan haideredzi zvakanyanya midzi yeropa mumoyo, ichideredza njodzi yematambudziko emwoyo.

Asi, unofanira kukurukura nezve mamiriro ako emoyo nachiremba wako usati watanga kushandisa lasmiditan. Kunyange zvazvo zvakachengeteka kune vazhinji varwere vane matambudziko emoyo, mamwe mamiriro akaoma emwoyo angaita kuti isakodzere. Chiremba wako achatarisa njodzi dzako dzega uye achasarudza kana lasmiditan yakakodzera mamiriro ako.

Ndoita Sei Kana Ndikashandisa Lasmiditan Yakawandisa Netsaona?

Kana netsaona ukatora lasmiditan yakawanda kupfuura yakarairwa, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira. Kutora yakawanda kunogona kuwedzera njodzi yako yezvinhu zvakakomba zvakadai sedzungu rakanyanya, kurara zvakanyanya, kana kuoma kufema.

Usaedze kuzvityaira kuti uwane rubatsiro, sezvo mushonga uyu unogona kukonzera kurara zvakanyanya uye dzungu. Ita kuti mumwe munhu akutyaira kuenda kuchipatara chekukurumidzira kana zvichikurudzirwa nachiremba wako. Uya nebhodhoro remushonga newe kuti vashandi vezvipatara vaone chaizvo zvawakatora uye zvawakatora zvakawanda sei.

Zviratidzo zvekuwandisa zvinogona kusanganisira kuneta kwakanyanya, kuvhiringidzika, kuoma kuramba wakamuka, kana matambudziko ekubatanidza. Kunyange kana ukanzwa zvakanaka pakutanga, zvakakosha kutsvaga rubatsiro rwekurapa, sezvo zvimwe zviitiko zvingasazviratidza nekukasira.

Ndoita Sei Kana Ndikakanganwa Dose yeLasmiditan?

Lasmiditan inotorwa chete kana uine migraine, kwete panguva dzose, saka haugone chaizvo

Kana usina chokwadi kana uchifanira kutora lasmiditan ye migraine yave ichienderera mberi kwenguva yakati rebei, taura nachiremba wako kuti uwane gwara. Vanogona kukubatsira kusarudza kana zvichiri kukosha kutora kana kana mamwe marapirwo angave akakodzera panguva iyoyo.

Ndingamira Rini Kutora Lasmiditan?

Unogona kumira kutora lasmiditan chero nguva, sezvo isiri mushonga unoda kumiswa zvishoma nezvishoma. Sezvo ichishandiswa chete kurwisa migraine imwe neimwe panzvimbo yekudzivirira zuva nezuva, hapana njodzi yezviratidzo zvekusiya kana ukamira.

Unogona kusarudza kumira kushandisa lasmiditan kana ukawana mamwe marapirwo achishanda zvakanyanya, kana ukawana mhedzisiro inonetsa, kana kana migraines yako ikava isingawanzoitika kana yakapfava. Vamwe vanhu vanomirawo pavanotanga kurapwa kwe migraine kunodzivirira kunoderedza kudiwa kwavo kwemishonga inokurumidza.

Usati wamira, kurukura sarudzo yako nachiremba wako, kunyanya kana lasmiditan yanga ichibatsira migraines yako. Vanogona kubatsira kuona kuti une dzimwe sarudzo dzekurapa dziripo uye vanogona kuratidza dzimwe nzira dzekugadzirisa mamiriro ako e migraine.

Ndingatora Lasmiditan nemimwe mishonga here?

Lasmiditan inogona kushamwaridzana nemimwe mishonga, saka zvakakosha kuti uudze chiremba wako nezve mishonga yese yekurapa, mishonga inotengeswa pasina mushonga, uye zvinowedzera zvauri kutora. Dzimwe nzira dzinogona kuwedzera mhedzisiro kana kuderedza kushanda.

Mishonga inogona kuwedzera mhedzisiro yekunyaradza doro, mapiritsi ekurara, mishonga yekuzvidya mwoyo, uye mamwe maantidepressants. Iyi musanganiswa inogona kukuitisa hope zvikuru kana dzungu, kuwedzera njodzi yako yekuwa kana tsaona. Chiremba wako angakurudzira kudzivisa aya masanganiswa kana kugadzirisa zviyero.

Nguva dzose taura nachiremba wako usati watanga mishonga mitsva uchishandisa lasmiditan. Vanogona kuongorora mikana yekudyidzana uye kukubatsira kuti utarise mishonga yako yese zvakachengeteka. Chengeta runyorwa rwemishonga yako yese kuti ugovane nachiremba chero upi zvake waunoona.