Chii chinonzi Lyme Disease Vaccine (Recombinant OspA): Zvinoshandiswa, Dosage, Side Effects uye Zvimwe

Lyme disease vaccine (recombinant OspA) mushonga wekudzivirira unodzivirira kubva kuLyme disease nekunangana neprotein chaiyo inowanikwa pamusoro pebhakitiriya rinokonzera hutachiona uhu. Mushonga uyu wakagadzirwa kubatsira vanhu vanogara kana kushanyira kazhinji nzvimbo dzakajairika Lyme disease, vachipa dziviriro isati yaitika tick exposure.

Nepo mushonga uyu waivepo muUnited States, wakabviswa mumusika muna 2001 nekuda kwekunetseka nezve zvinogona kukonzera side effects uye mhosva. Zvisinei, shanduro itsva dzemishonga yeLyme disease dziri kugadzirwa uye kuyedzwa, nedzimwe dzichiratidza mhedzisiro inovimbisa mumiedzo yekiriniki.

Chii chinonzi Lyme Disease Vaccine (Recombinant OspA)?

Lyme disease vaccine mushonga wakagadzirwa murabhoritari une shanduro yakagadzirwa nejenetiki yeiyo yekunze pamusoro protein A (OspA) kubva kuLyme disease bhakitiriya. Iyi protein inoita sebasa rekudzidzisa immune system yako, ichiidzidzisa kuziva nekurwisa bhakitiriya chaiyo kana iwe ukambosangana.

Mushonga unoshanda nekukurudzira muviri wako kuti ugadzire antibodies kurwisa Lyme disease bhakitiriya. Kana tick inotakura mabhakitiriya aya ikakuruma, ma antibodies anogona kuparadza mabhakitiriya asati ava nemukana wekukonzera hutachiona. Funga nezvazvo sekupa immune system yako kutanga muhondo kurwisa Lyme disease.

Rudzi urwu rwemushonga runonzi

Mushonga weLyme disease wakagadzirirwa kudzivirira chirwere cheLyme disease muvanhu vari panjodzi huru yekubatwa nezvikwekwe. Zvinonyanya kubatsira kune vanhu vanopedza nguva yakawanda vari panze munzvimbo dzakajairika zvikwekwe zvine hutachiona.

Vanhu vangabatsirwa nemushonga uyu vanosanganisira avo vanoshanda kana kuzvivaraidza munzvimbo dzine miti, uswa, kana nzvimbo dzine makwenzi uko zvikwekwe zvembudzi zvinogara. Izvi zvinosanganisira vafambi, vanokamisa, vavhimi, vanogadzira nzvimbo, vashandi vemasango, uye chero munhu anogara munzvimbo dzakadai sedzimwe nzvimbo dzekuchamhembe kwakadziva kumabvazuva uye kumusoro kwemahombekombe eUnited States.

Mushonga uyu unonyanya kukosha nekuti Lyme disease inogona kukonzera matambudziko akakomba enguva refu kana ikasabatwa. Izvi zvinogona kusanganisira matambudziko emajoini, matambudziko emoyo, uye zviratidzo zvepfungwa zvinogona kuramba kwemwedzi kana makore.

Mushonga weLyme Disease Unoshanda Sei?

Mushonga weLyme disease unoshanda kuburikidza nemaitiro akasiyana anomisa hutachiona pachinobva. Paunogamuchira mushonga, immune system yako inogadzira maantibodies kurwisa OspA protein inowanikwa pamabhakitiriya eLyme disease.

Zvinotevera ndizvo zvinoitika kana chikwekwe chikurumira mushure mekubaiwa. Chikwekwe chinotora ropa rako, iro zvino rine maantibodies aya anodzivirira. Maantibodies aya anobva arwisa mabhakitiriya eLyme anogara mudumbu rechikwekwe, achivauraya vasati vakwanisa kuenda kumate echikwekwe uye kupinda muropa rako.

Maitiro aya anowanzo tora maawa makumi maviri nemana kusvika makumi mana nemasere, ndosaka mushonga uyu uchibudirira kunyangwe chikwekwe chakanamatira. Mushonga uyu unochinja ropa rako kuita chombo kurwisa mabhakitiriya, kukudzivirira kubva mukati.

Izvi zvinoonekwa sechiyero chekudzivirira chine simba, chichipa dziviriro yakakosha kana chishandiswa nemazvo. Zvisinei, haina 100% kubudirira, saka dzimwe nzira dzekudzivirira zvikwekwe dzinoramba dzichikosha kunyangwe mushure mekubaiwa.

Ndingatora Sei Mushonga weLyme Disease?

Mushonga wejekiseni reLyme disease unopiwa nejojo mumusoro wemutsipa wako. Mushonga wekutanga waida majekiseni matatu mukati megore kuti upe dziviriro yakazara, kunyangwe majekiseni matsva ari kugadzirwa anogona kuva nemarongero akasiyana ekupa mishonga.

Unogona kugamuchira mushonga uyu uine kana usina chikafu, sezvo kudya kusingakanganisi kuti mushonga unoshanda sei. Hapana zvirambidzo zvakakosha zvekudya usati kana wapedza kuwana jojo, uye unogona kuchengetedza chirongwa chako chekudya chakajairika.

Jojo racho pacharo rinokurumidza uye rakaita semamwe majekiseni enguva dzose. Mupi wako wehutano achachenesa nzvimbo yekujekiseni ne doro uye achapa mushonga achishandisa tsono yakachena. Unogona kunzwa kubaya kana kurwadziwa kwenguva pfupi, asi kusagadzikana kunowanzoita kushoma uye kunogara kwenguva pfupi.

Mushure mekuwana mushonga, unogona kutangazve mabasa ako akajairika nekukasira. Vamwe vanhu vanosarudza kuzorora kwezuva rose, asi izvi hazvidiwi zvekurapa kunze kwekunge uine mhedzisiro.

Ndingatora Mushonga weLyme Disease Kwenguva Yakareba Sei?

Mushonga weLyme disease unoda akateedzana emajekiseni panzvimbo yemishonga yezuva nezuva inoramba ichitorwa. Chirongwa chejekiseni chekutanga chaibatanidza zvikamu zvitatu: chikamu chekutanga, chikamu chechipiri mwedzi mumwe gare gare, uye chikamu chechitatu chakapiwa mwedzi gumi nemiviri mushure mechikamu chekutanga.

Dziviriro inotanga kukura mushure mechikamu chechipiri, asi kusadzivirirwa kwakanyanya kunoitika mushure mekupedza zvikamu zvitatu zvese. Dziviriro iyi yakazara inogona kugara kwemakore akati wandei, kunyangwe nguva chaiyo yekusadzivirirwa ichiri kudzidzwa mumafomu matsva emushonga.

Majojo ekuwedzera anogona kudikanwa makore mashoma ega ega kuti achengetedze dziviriro, yakafanana nemamwe majekiseni senge tetanus. Mupi wako wehutano achabatsira kuona chirongwa chakakodzera zvichienderana nezvinhu zvako zverisiko uye fomu chaiyo yemushonga iripo.

Nguva yekudzivirirwa kwako inofanira kurongwa kuitira kuti uve nekudzivirirwa tick mwaka usati watanga munzvimbo yako, kazhinji kutanga muzhizha uye kuenderera mberi kusvika kutanga kwematsutso.

Ndezvipi Zvakaipa zveLyme Disease Vaccine?

Vanhu vazhinji vanogamuchira Lyme disease vaccine vanowana matambudziko madiki anopera ega mukati memazuva mashoma. Izvi zvinowanzoita zviratidzo zvekuti immune system yako iri kupindura zvakakodzera kumushonga.

Zvakajairika zvinogona kuitika zvinosanganisira kurwadziwa, kutsvuka, kana kuzvimba panzvimbo yekujova. Izvi zvinowanzoitika mukati meawa mushure mekubaiwa uye zvinowanzoita nani mukati me2-3 mazuva. Unogonawo kuona humwe hunyoro paunenge uchifambisa ruoko rwako.

Vamwe vanhu vanowana zviratidzo zvishoma zvesystemic zvinogona kusanganisira: - Fever yakaderera - Kuneta kana kunzwa kuneta - Kurwadziwa nemusoro - Kurwadziwa kwemhasuru - Chills

Izvi zviratidzo zvinowanzoita zvishoma uye zvinopera mukati me24-48 maawa. Zvinoitika nekuti immune system yako iri kupindura kumushonga.

Zvimwe zvinokuvadza zvakanyanya hazviwanzoitiki asi zvinogona kusanganisira allergic reactions. Zviratidzo zve allergic reaction yakakomba zvinosanganisira kuoma kufema, kuzvimba kwechiso kana huro, kukurumidza kurova kwemoyo, dzungu, kana rash yakapararira. Kana iwe ukaona chero eaya zviratidzo, tsvaga rubatsiro rwekurapa nekukurumidza.

Vamwe vanhu vanogona kuwana kurwadziwa kwemajoini kana kuoma, kunyanya mumabvi, izvo zvakanga zviri kunetsekana neyekutanga vaccine formulation. Zvisinei, majekiseni matsva ari mukuvandudzwa akagadzirirwa kuderedza njodzi iyi.

Ndiani Asingafaniri Kutora Lyme Disease Vaccine?

Vanhu vakati wandei vanofanira kudzivisa Lyme disease vaccine nekuda kwenjodzi yakawedzerwa yematambudziko kana kuderedzwa kwemigumisiro. Mupi wako wehutano achatarisa nhoroondo yako yekurapa kuti aone kana mushonga wakakodzera kwauri.

Hamufaniri kugamuchira mushonga uyu kana muine allergy yakakomba kune chero chimwe chezvinhu zvawo. Vanhu vane nhoroondo yekurwara zvakanyanya kune zvikamu zvekare zvejekiseni vanofanirwawo kudzivisa zvikamu zveramangwana.

Mushonga uyu haukurudzirwi kune vanhu vane mamwe mamiriro eautoimmune, kunyanya ayo anokanganisa majoini. Izvi zvinosanganisira rheumatoid arthritis, lupus, kana dzimwe chirwere chekuputika kwemajoini, sezvo mushonga uyu ungangoita kuti mamiriro aya awedzere.

Vakadzi vane pamuviri uye vanoyamwisa vanofanira kukurukura njodzi nemabhenefiti nachiremba wavo, sezvo data rekuchengetedza munharaunda idzi rinogona kunge rakaganhurirwa. Vana vari pasi pezera rakati vanogonawo kuda kumirira, zvichienderana nemafomu chaiwo ejekiseni uye mazinga ezera akatenderwa.

Vanhu vane immune systems dzakakanganiswa, senge avo vari kugamuchira chemotherapy kana kutora mishonga yekudzivirira immune, vangasaite zvakanaka kumushonga. Chiremba wako achaongorora kana mushonga uyu uchizoita zvakanaka mumamiriro ako ezvinhu.

Mazita eBrand eLyme Disease Vaccine

Mishonga yekutanga yeLyme disease yakatengeswa pasi pezita rebrand LYMErix naGlaxoSmithKline. Zvisinei, mushonga uyu wakabviswa nemaune kubva kumusika weU.S. muna 2001 nekuda kwekunetseka pamusoro pemigumisiro inogona kuitika uye matambudziko emutemo.

Parizvino, hapana mishonga yeLyme disease yakatenderwa neFDA inowanikwa kune vanhu muUnited States. Zvisinei, makambani akati wandei emishonga ari kugadzira mishonga mitsva inogona kuwanikwa mumakore ari kuuya.

VLA15 imwe mushonga unovimbisa uri kugadzirwa neValneva naPfizer. Mushonga uyu unotarisa mapuroteni akawanda ekunze eLyme disease mabhakitiriya uye parizvino ari mumiedzo yekiriniki yekupedzisira.

Imwe mushonga uri mukugadzirwa unonzi MV-B, uyo unoshandisa imwe nzira yekukurudzira immune kurwisa Lyme disease. Mishonga mitsva iyi yakagadzirirwa kuva yakachengeteka uye inoshanda kupfuura fomu rekutanga.

Nzira Dzimwe Dzokudzivirira Chirwere cheLyme

Panguva yekumirira majekiseni matsva kuti awanikwe, dzimwe nzira dzinoshanda dzinogona kukubatsira kukudzivirira kubva kuchirwere cheLyme. Nzira idzi dzekudzivirira dzinotarisa pakudzivisa kurumwa netikiti uye kubvisa matikiti nekukurumidza kana akabatana.

Matanho ekuzvidzivirira ndiyo mutsara wako wekutanga wekuzvidzivirira. Kupfeka mabhurukwa marefu, mashati marefu-maoko, uye shangu dzakavharwa-zvigunwe kana uri munzvimbo dzine matikiti zvinogona kuderedza zvakanyanya njodzi yako. Mbatya dzemavara akajeka dzinokubatsira kuona matikiti vasati vabatana.

Zvinodzivirira zvipembenene zvine DEET, picaridin, kana permethrin zvinoshanda zvakanyanya pakudzivirira matikiti. Zvinodzivirira zvine DEET zvinoshanda zvakanaka paganda rakashama, nepo permethrin inogona kushandiswa pamabhurukwa nemidziyo yekudzivirira kwenguva refu.

Kutarisa matikiti nguva dzose kwakakosha, kunyanya mushure mekupedza nguva uri panze. Ongorora muviri wako wese, uchinyatso tarisa nzvimbo idzo matikiti anofarira kuvanzira, senge musoro, kumashure kwenzeve, pasi pemapfupa, uye nzvimbo yegroin.

Kugadzirisa nzvimbo dzakapoteredza imba yako kunogonawo kuderedza huwandu hwematikiti. Kuchengeta huswa hupfupi, kubvisa mashizha, uye kugadzira mhinganidzo pakati penzvimbo dzine miti nenzvimbo dzekunakidzwa kunogona kuita kuti imba yako isakwezve matikiti.

Kana ukawana tikiti rakabatana, kubviswa nekukurumidza mukati meawa makumi maviri nemana kunoderedza zvakanyanya njodzi yekutapurirana chirwere cheLyme. Shandisa tweezers dzine mazano akanaka kubata tikiti pedyo neganda uye dhonza zvishoma nezvishoma kumusoro.

Ko Jekiseni reChirwere cheLyme Riri Nani Pane Kudzivirira kweDoxycycline Here?

Jekiseni rechirwere cheLyme uye doxycycline zvinoshanda zvakasiyana mukudzivirira chirwere cheLyme, uye imwe neimwe ine zvainobatsira zvichienderana nemamiriro ako ezvinhu. Jekiseni rinopa dziviriro yenguva refu pasina kudiwa kwemishonga yezuva nezuva, nepo doxycycline ichipa dziviriro yenguva pfupi mushure mekusangana netikiti rine njodzi yakanyanya.

Mushonga wejekiseni ungave wakakodzera kune vanhu vanosangana nguva dzose nemakona, vakaita sevaya vanoshanda panze kana kugara munzvimbo dzine njodzi huru. Kana wapedza jekiseni, ungave nekudzivirirwa kwemakore usingade kuyeuka mishonga yezuva nezuva kana kunetseka nezve mhedzisiro kubva mukushandisa maantibayoti kazhinji.

Doxycycline, kune rimwe divi, iripo parizvino uye inogona kushandiswa sepost-exposure prophylaxis kana wakamwa nekena ine njodzi huru. Inowanzo kupiwa sedosi imwe mukati me72 maawa ekubviswa kwekena uye inoshanda zvakanyanya pakudzivirira chirwere cheLyme mumamiriro ezvinhu aya.

Nzira yejekiseni ingave yakakwirira pakudzivirira kwakagadzikana, kwenguva refu, nepo doxycycline ichishanda zviri nani pakuwanzana, njodzi huru. Zvisinei, sezvo pasina jekiseni riripo parizvino, doxycycline inoramba iri chishandiso chekutanga chekurapa chekudzivirira mumamiriro ezvinhu ekupedzisira.

Mibvunzo Inowanzo Bvunzwa Nezve Lyme Disease Vaccine

Jekiseni reLyme Disease Rakachengeteka Kune Vanhu vane Arthritis Here?

Vanhu vane arthritis vanofanira kukurukura jekiseni zvakanyatsonaka nemupi wavo wehutano, sezvo panogona kuve nenjodzi dzakawedzerwa. Jekiseni rekutanga reLyme disease raive rakabatana nemhedzisiro ine chekuita nemajoini kune vamwe vanhu, kunyanya avo vane mamiriro emajoini aripo.

Kutya kunobva pachokwadi chekuti iyo OspA protein inoshandiswa mujekiseni inogovana zvimwe zvakafanana nemapuroteni evanhu anowanikwa mumativi emajoini. Iyi molecular mimicry inogona kukonzera autoimmune response muvanhu vanotambudzika, zvichitungamira mukuzvimba kwemajoini kana kuwedzera kwezviratidzo zvearthritis zviripo.

Zvisinei, majekiseni matsva ari mukugadzirwa akagadzirirwa kuderedza njodzi idzi kuburikidza nekuvandudzwa kwefomula uye zvakasiyana mapuroteni. Rheumatologist yako kana mupi wekutanga wekutarisira anogona kubatsira kuyera mabhenefiti anogona kuitika pamusoro penjodzi zvichibva pamhando yako chaiyo yearthritis uye hutano hwese.

Ndingaita Sei Kana Ndikawana Mishonga Yakawanda Yemushonga WeLyme Disease Netsaona?

Kana netsaona ukawana mushonga wakawanda weLyme disease, usavhunduka. Kunyange zvisina kunaka, kuwana mishonga yakawanda kazhinji hakuunzi kukuvadza kwakakura kunze kwemigumisiro yakawedzera panzvimbo yekubaiwa.

Taura nachiremba wako kuti utaure nezvemushonga wakawanda uye ukurukure chero zviratidzo zvaungave nazvo. Vanogona kuda kukutarisa zvakanyanya kuti vaone migumisiro uye vagadzirise hurongwa hwako hwejekiseni remangwana zvinoenderana.

Unogona kuona maitiro akajeka emuno, akadai sekuwedzera kurwadziwa, kuzvimba, kana kutsvuka panzvimbo yekubaiwa. Zviratidzo zve systemic zvakaita sefivha kana kurwadziwa kwemuviri zvinogonawo kuoneka zvakanyanya. Izvi zvinokonzeresa zvinowanzoitika kwenguva pfupi uye zvinopera mukati memazuva mashoma.

Chengeta rekodhi yemishonga yese yaunogamuchira, kusanganisira iyo netsaona, kubatsira chiremba wako kuronga hurongwa hwako hwejekiseni remangwana. Ruzivo urwu ruchakosha pakuona kuti ungada riini mishonga yekusimudzira.

Ndingaita Sei Kana Ndikarasikirwa Nemushonga WeLyme Disease?

Kana ukakanganwa mushonga wakarongwa weLyme disease, taura nachiremba wako nekukurumidza sezvinobvira kuti urongezve. Nguva iri pakati pemishonga yakakosha kuti uwane dziviriro yakanaka, asi kukanganwa mushonga hazvirevi kuti unofanirwa kutangazve akateedzana.

Chiremba wako anogona kukurudzira kuwana mushonga wakarasika nekukurumidza sezvinobvira, wobva wenderera mberi nehurongwa hwekutanga. Mhinduro yekudzivirira inogona kuchengetwa kunyangwe nekunonoka, kunyangwe dziviriro yako ingaderedzwa kusvikira wapedza akateedzana akazara.

Kana wakanganwa mushonga wechipiri, unogona kunge usina dziviriro yakawanda panguva yechando chepamusoro. Funga kuve akanyanya kungwarira nezve matanho ekudzivirira tick kusvikira iwe uchikwanisa kudzokera panzira nehurongwa hwako hwejekiseni.

Usayedze "kuzadza" mushonga wakarasika nekutora mishonga yakawanda panguva imwe chete. Namatira pakati pezvikamu zvinokurudzirwa pakati pemishonga kuti uve nechokwadi chekuti muviri wako unopindura zvakanaka uye kuderedza mhedzisiro yakaipa.

Ndingamira Rini Kutora Mushonga weLyme Disease?

Sarudzo yekumira kuwana majekiseni eLyme disease boosters inoenderana nenjodzi yako yekugara uchibatwa nemakona uye mazano echiremba wako. Kusiyana nemishonga yezuva nezuva, haumire "kutora" mushonga, asi panzvimbo pezvo unosarudza kana uchaenderera mberi nemishonga yeboster periodic.

Kana usisagare kana kushanyira nzvimbo dzakajairika Lyme disease, unogona kusarudza kuti mishonga yeboster haina kukosha. Zvisinei, yeuka kuti zvirwere zvinotakurwa nemakona zviri kuwedzera munzvimbo itsva dzegeography, saka kuongorora kwako njodzi kunogona kuchinja nekufamba kwenguva.

Vanhu vanoramba vachibatwa nemakona nguva dzose, vakaita sevashandi vekunze kana vafambi vanofarira, vangangobatsirwa nekuenderera mberi nemajekiseni ebooster kuti vachengetedze dziviriro. Chiremba wako anogona kukubatsira kuongorora njodzi dzako dziripo.

Kureba kwedziviriro kubva kumushonga hauna kugadzwa zvizere kune mafomu matsva, saka mazano ekuti booster ingaitwa rini anogona kuchinja sezvo rumwe ruzivo ruchiwanzowanikwa kubva mukudzidza kuri kuitwa.

Ndingawana Mushonga weLyme Disease here kana ndakambove neLyme Disease?

Kuve neLyme disease kare hakukudzivisi kuwana mushonga, uye kutaura zvazviri, unogona kubatsirwa kubva mukubaiwa. Hutachiona hwemuviri hahupi dziviriro yakakwana kana inogara kwenguva refu, uye kutapukirwa patsva neLyme disease zvinogoneka.

Mushonga unogona kupa dziviriro yakagadzikana uye inotarisirwa kupfuura dziviriro yemuviri wega. Vamwe vanhu vakambove neLyme disease vanogadzira maantibodies anogona kukanganisa mamwe ma laboratory tests, asi izvi hazvikanganisi kuchengeteka kana kushanda kwemushonga.

Unofanira kumirira kusvikira wapedza kupora kubva kune chero kurapwa kwechirwere cheLyme usati wadzivirirwa. Mukoti wako wehutano achada kuona kuti chero hutachiona hunoshanda hwapera zvachose usati wamutsa immune system yako nemushonga.

Kana wakambove nechirwere cheLyme chisingaperi kana zviratidzo zvenguva refu, kurukura nguva yekudzivirira nemukoti wako wehutano. Vanogona kukurudzira kumirira kusvikira zviratidzo zvako zvagadziriswa usati waenderera mberi nekudzivirirwa.