Chii chinonzi Macimorelin: Zvinoshandiswa, Madosi, Mativi eMuviri uye Zvimwe

Macimorelin mushonga unopiwa nachiremba unobatsira vanachiremba kuongorora kushomeka kwehomoni yekukura muvanhu vakuru. Inoshanda nekukurudzira muviri wako kuti ubudise homoni yekukura, iyo vanachiremba vanogona kuyera kuburikidza nemiedzo yeropa kuti vaone kana gland yako yepituitary ichishanda nemazvo.

Mushonga uyu unouya semushonga wemuromo waunonwa, zvichiita kuti ive sarudzo iri nyore kuenzanisa nemiedzo yekare yekuongorora yaida majekiseni. Chiremba wako achashandisa macimorelin sechikamu chekuongorora kwakazara kuti anzwisise kana muviri wako uchigadzira homoni yekukura yakakwana zvakasikwa.

Chii chinonzi Macimorelin chinoshandiswa?

Macimorelin yakagadzirirwa kunyanya kuongorora kushomeka kwehomoni yekukura yevakuru (AGHD). Kana vanachiremba vachifungidzira kuti unogona kunge uine mamiriro aya, vanoda nzira yakavimbika yekuyedza kuti gland yako yepituitary inogadzira sei homoni yekukura.

Mushonga unoshanda sechishandiso chekuongorora panzvimbo pekurapa. Funga nezvayo semuedzo wekushushikana we gland yako yepituitary - inodenha muviri wako kuti ubudise homoni yekukura kuitira kuti vanachiremba vagone kuyera mhinduro. Izvi zvinovabatsira kuona kana zviratidzo zvako zvine chekuita nekushomeka kwehomoni yekukura kana imwe mamiriro.

Kushomeka kwehomoni yekukura muvanhu vakuru kunogona kukonzera kuneta, kusimba kwemhasuru, kuwedzera mafuta emuviri, uye kuderedzwa kwemhando yehupenyu. Kuva neongororo yakarurama ndiyo nhanho yekutanga yekuwana kurapwa kwakakodzera kana uine mamiriro aya.

Macimorelin inoshanda sei?

Macimorelin inoshanda nekutevedzera homoni yechisikigo inonzi ghrelin, iyo inoratidza gland yako yepituitary kuti ibudise homoni yekukura. Inoonekwa seyakasimba homoni yekukura secretagogue, zvinoreva kuti inoshanda zvakanyanya pakukonzera mhinduro iyi.

Paunotora macimorelin, inosungirira kune mamwe ma receptors ari mugland yako ye pituitary uye hypothalamus. Iyi binding action inotumira chiratidzo chakasimba chekusunungura hormone yekukura muropa rako. Mushonga unosvika pakukwirira kwekushanda mukati memaminitsi makumi mana nemashanu kusvika awa rimwe mushure mekuutora.

Vashandi vehutano vako vachatora mienzaniso yeropa panguva dzakatarwa mushure mekutora mushonga kuyera kuti muviri wako unogadzira hormone yekukura yakawanda sei. Mhinduro yakajairika inoratidza kuti gland yako ye pituitary iri kushanda zvakanaka, nepo mhinduro isina kunaka ingaratidza kushomeka kwehormone yekukura.

Ndingatora sei Macimorelin?

Uchatora macimorelin semushonga mumwe chete muhofisi yachiremba wako kana nzvimbo yekurapa, kwete kumba. Mushonga uyu unouya semushonga wemuromo waunonwa, uye maitiro ese anoda kutariswa kwekurapa.

Usati watora macimorelin, uchada kutsanya kwemaawa angangoita 8 - izvi zvinoreva kuti hapana chikafu, asi unogona kazhinji kuva nemvura. Chiremba wako achakupa mirairo chaiyo yekuti ungamira rini kudya nekunwa usati waita bvunzo yako. Iyi nguva yekutsanya yakakosha nekuti chikafu chinogona kukanganisa mhedzisiro yebvunzo.

Mushonga wacho unonaka zvishoma, uye uchanwa dose yese kamwechete. Mushure mekuutora, uchagara panzvimbo yekurapa kwemaawa akati wandei apo vashandi vehutano vanotora mienzaniso yeropa panguva dzakatarwa kuyera mazinga ako e hormone yekukura.

Munguva yekuedzwa, uchada kugara wakasununguka uye kudzivisa basa remuviri, sezvo kurovedza muviri kunogonawo kukanganisa mazinga e hormone yekukura. Vashandi vehutano vako vachakutarisa mukati memaitiro ese kuti vaone kuti unonzwa wakasununguka uye wakachengeteka.

Ndingatora Macimorelin kwenguva yakareba sei?

Macimorelin ibvunzo yekuziva kamwechete, kwete kurapwa kuri kuenderera mberi. Uchaizotora kamwechete panguva yekushanya kwako kunzvimbo yekurapa kuti uedzwe kushomeka kwe hormone yekukura.

Maitiro ese ekuongorora anowanzo tora maawa 3-4 kubva panguva yaunotora mushonga kusvika masampuli ese eropa aunganidzwa. Nguva yakawanda iyi inosanganisira kumirira pakati pekubvisa ropa pane chero kurapwa kunoshanda.

Kana chiremba wako achida kudzokorora bvunzo nechikonzero chipi zvacho, vachasarudza nguva yekusangana yakasiyana. Zvisinei, vanhu vazhinji vanongoda kuti bvunzo iyi iitwe kamwe chete kuti vawane mufananidzo wakajeka wemamiriro avo ekuwedzera mahomoni.

Ndezvipi Zvipingamupinyi zveMacimorelin?

Vanhu vazhinji vanoshivirira macimorelin zvakanaka, asi semushonga chero upi zvake, unogona kukonzera mhedzisiro. Izvo zvakajairika zvinowanzoita zvinyoro uye zvenguva pfupi, zvichiitika panguva kana nguva pfupi mushure mebvunzo.

Heano mhedzisiro yaungasangana nayo panguva kana mushure mekutora macimorelin:

• Kusvotwa kana kunzwa kusagadzikana
• Dizziness kana lightheadedness
• Kutemwa nemusoro
• Kuneta kana kuneta
• Nzara yakawedzera
• Kuchinja mukuravira
• Kusagadzikana mudumbu

Izvi zvinowanzoitika zvinowanzoenda zvega mukati memaawa mashoma. Chikwata chekurapa chiri kuongorora bvunzo yako chichatarisa izvi zviitiko uye chinogona kukubatsira kuti unzwe wakasununguka kana zvikaitika.

Nepo zvisingawanzoitiki, vamwe vanhu vanogona kusangana nemhedzisiro yakakura inoda kutariswa kwekurapa nekukurumidza. Izvi zviitiko zvakakomba hazviwanzoitiki asi zvakakosha kuziva:

• Dizziness yakanyanya kana kufenda
• Kukurumidza kana kusina kujairika kwemoyo
• Kufema kwakaoma
• Kusvotwa kwakanyanya kana kurutsa
• Allergic reactions senge rash, itching, kana kuzvimba

Sezvo iwe uchave uri muchivakwa chekurapa panguva yebvunzo, vanopa hutano vanogona kukurumidza kugadzirisa chero zviratidzo zvinonetsa zvingamuka. Iyi nzvimbo inotarisirwa inovimbisa kuchengeteka kwako mukati mekuongorora.

Ndiani Asingafaniri Kutora Macimorelin?

Vanhu vakati wandei vanofanira kudzivisa macimorelin nekuda kwezvikonzero zvekuchengeteka kana njodzi yekusaziva mhedzisiro yekuedzwa. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akurudzira bvunzo iyi.

Haufaniri kutora macimorelin kana uine chero imwe yemamiriro aya:

• Kuziva allergy ku macimorelin kana zvigadzirwa zvayo
• Matambudziko akakomba echiropa kana chirwere chechiropa chinoshanda
• Chirwere chakakomba cheitsvo
• Kutadza kwemoyo munguva pfupi yapfuura kana mamiriro emoyo asina kugadzikana
• Kusadzora ropa rakakwira
• Tumors inoshanda ye pituitary

Kuzvitakura nekuyamwisa zvinodawo kufunga kwakakosha, sezvo kuchengeteka kwe macimorelin kusati kwagadzwa mumamiriro ezvinhu aya. Chiremba wako achakurukura dzimwe nzira dzekuedzwa kana iwe wakazvitakura kana kuyamwisa.

Mishonga yakati wandei inogona kukanganisa kushanda kana kuchengeteka kwe macimorelin. Ita shuwa kuti uudze chiremba wako nezve mishonga yese yaunotora, kusanganisira:

• Zvimwe zvinowedzera hormone yekukura
• Corticosteroids
• Mishonga inokanganisa rhythm yemoyo
• Mishonga yeropa
• Mishonga yechirwere cheshuga

Mupi wako wehutano achabatsira kuona kana macimorelin akachengeteka uye akakodzera mamiriro ako chaiwo. Vanogona kukurudzira dzimwe nzira dzekuedzwa kana uine chero contraindications.

Mazita eMacimorelin Brand

Macimorelin inowanikwa pasi pezita rekuti Macrilen muUnited States. Iyi ndiyo chete fomu iripo yekutengeserana yemushonga uyu.

Macrilen inogadzirwa neAeterna Zentaris uye yakagadzirirwa kunyatsoongorora kushomeka kwehomoni yekukura kwevanhu vakuru. Chiremba wako achazvireva nezita rimwe chete - macimorelin kana Macrilen - uye zvinoreva mushonga mumwe chete.

Sezvo iri mushonga wekuongorora wakakosha, unowanikwa chete kuburikidza nenzvimbo dzekutarisira hutano dzinogadzira bvunzo dzehormone yekukura. Hauzoiwani kumafemu akajairika nekuti inoda kutariswa kwechiremba panguva yekushandisa.

Zvimwe Zvinhu Zvokutsiva Macimorelin

Mamwe bvunzo akati wandei anogona kuongorora kushomeka kwehormone yekukura, kunyangwe imwe neimwe iine zvainobatsira uye zvipingamupinyi zvayo. Chiremba wako achasarudza sarudzo yakanakisa zvichienderana nemamiriro ako chaiwo uye nhoroondo yako yekurapa.

Bvunzo yekushivirira insulin (ITT) inoonekwa seyakajairika yegoridhe pakuongorora kushomeka kwehormone yekukura. Zvisinei, inoda kutariswa zvakanaka nekuti inosanganisira kudzikisa shuga yeropa rako nemaune, izvo zvinogona kusagadzikana uye zvinogona kuva nengozi kune vamwe vanhu.

Bvunzo yekukurudzira arginine imwe imwe nzira inowanzova yakachengeteka kupfuura ITT. Arginine iamino acid inokurudzira kuburitswa kwehormone yekukura, asi haina simba se macimorelin uye inogona kusashanda zvakanaka mune vese varwere.

Bvunzo yekukurudzira glucagon inopa imwe sarudzo, kunyanya kune vanhu vasingakwanise kuita bvunzo yekushivirira insulin zvakachengeteka. Glucagon ihomoni inokurudzira zvisina kunanga kuburitswa kwehormone yekukura, kunyangwe inogona kukonzera kusvotwa kazhinji kupfuura macimorelin.

Chiremba wako achafunga nezvezvinhu zvakaita sezera rako, hutano hwese, mamwe mamiriro ekurapa, uye mhedzisiro yekuedzwa yapfuura pakusarudza nzira yakakodzera yekuongorora iwe.

Macimorelin Ari Nani Kupfuura Zvimwe Zviedzo zveGrowth Hormone Here?

Macimorelin inopa zvakawanda zvakanakira pamusoro pezviedzo zvechinyakare zvegrowth hormone, zvichiita kuti ive sarudzo inofarirwa mumamiriro akawanda. Inowanzova yakachengeteka uye yakasununguka kupfuura dzimwe nzira dzimwe nguva ichipa mhedzisiro yakavimbika.

Kana tichienzanisa nemuedzo wekushivirira insulin, macimorelin akachengeteka zvikuru nekuti haana njodzi yekukonzera shuga yeropa yakaderera zvikuru. Muedzo weinsulin unogona kuva nengozi zvikuru kuvanhu vane chirwere chemoyo, matambudziko ekubata, kana chirwere cheshuga, asi macimorelin akachengeteka kuvanhu vazhinji.

Macimorelin zvakare yakasununguka kupfuura miedzo inobva mukudzora. Iwe unongonwa mushonga panzvimbo yekugamuchira majekiseni, ayo vanhu vazhinji vanowana akasununguka. Nzira yekunwa zvakare inobvisa kunetseka pamusoro pekuita kwenzvimbo yekudzora kana kushushikana kunoenderana netsinga.

Muedzo unopa mhedzisiro yakavimbika sezvakaita nzira dzechinyakare. Zvidzidzo zvinoratidza kuti macimorelin inonyatsoziva kushomeka kwehomoni yekukura nekunzwa kwakanyanya uye specificity, zvinoreva kuti inonyatsoziva vanhu vane mamiriro acho ezvinhu uye avo vasina.

Zvisinei, macimorelin haisi nani otomatiki kune munhu wese. Vamwe vanhu vangangoda miedzo imwe zvichienderana nemamiriro avo chaiwo ekurapa kana kana mhedzisiro yekutanga isina kujeka. Chiremba wako achakubatsira kuona kuti ndeupi muedzo wakakodzera mamiriro ako ega.

Mibvunzo Inowanzo Bvunzwa Nezve Macimorelin

Macimorelin Yakachengeteka Kuvanhu Vane Chirwere Cheshuga Here?

Macimorelin inogona kushandiswa zvakachengeteka muvanhu vane chirwere cheshuga, asi inoda kunyatsoongororwa. Kusiyana nemiedzo yekushivirira insulin, macimorelin haikonzeri kudonha kunotyisa kweshuga yeropa.

Zvisinei, iwe uchiri kuda kutsanya usati waita muedzo, izvo zvinogona kukanganisa kudzora shuga yeropa rako. Chiremba wako achashanda newe kuti agadzirise mishonga yako yeshuga zvakachengeteka panguva yekuedzwa. Vanogona kukurudzira kutarisa shuga yako yeropa kakawanda usati waita uye mushure memuedzo.

Kuda kutsanya kunowanzoita maawa masere, izvo zvinogoneka kuvanhu vazhinji vane chirwere cheshuga. Chikwata chako chehutano chichakutarisa zvakanyanya panguva yemuedzo kuti uve nechokwadi chekuti shuga yako yeropa inoramba iri mukati mehuwandu hwakachengeteka.

Ndingaita Sei Kana Ndikanzwa Kurwara Munguva yeMacimorelin Test?

Kana ukanzwa kusvotwa, dzungu, kana kusanzwa zvakanaka panguva yekuedzwa, udza chikwata chako chehutano nekukasira. Vakadzidziswa kubata nemamiriro ezvinhu aya uye vanogona kukubatsira kuti unzwe zviri nani.

Pakupera kusvotwa, vanogona kupa mushonga wekurwisa kusvotwa kana kuratidza shanduko dzemaitiro dzinogona kubatsira. Kana ukanzwa dzungu, vanogona kukuyamwisa pasi uye vachatarisa ropa rako uye kumhanya kwemoyo.

Rangarira kuti uri muchipatara panguva yekuedzwa kwese, saka rubatsiro rwehunyanzvi runowanikwa nguva dzose. Usazeze kutaura nezve kusagadzikana kupi zvako - chikwata chako chehutano chinoda kuona kuti wakachengeteka uye wakasununguka sezvinobvira.

Ndingatyaira Kumba Mushure mekutora Macimorelin?

Unofanira kuronga kuti mumwe munhu akutyairire kumba mushure mekuongororwa kwe macimorelin. Mushonga uyu unogona kukonzera dzungu, uye wakanga uchitsanyawo, izvo zvinogona kukanganisa kunyatsoteerera kwako uye nguva yekupindura.

Nzvimbo zhinji dzekurapa dzinokurudzira kuva neshamwari kana nhengo yemhuri inokutora, kana kushandisa sevhisi yekufamba panzvimbo yekuzvityaira. Iyi ndiyo chenjedzo yekuchengetedza kukudzivirira iwe nevamwe vatyairi mumugwagwa.

Iwe unowanzozonzwa zvakajairika mukati memaawa mashoma mushure mekuongororwa, asi zviri nani kungwarira. Ronga kuzorora kwezuva rose uye kutangazve mabasa ako akajairika zuva rinotevera.

Ndingaziva Rini Mhedzisiro Yangu Yekuedzwa?

Chiremba wako anowanzo kuva nemhedzisiro yekutanga mukati memazuva mashoma kusvika vhiki mushure mekuongororwa kwako. Mienzaniso yeropa inoda kuongororwa murabhoritari, uye mhedzisiro inoda kunzwisiswa zvakanyanya.

Mupi wako wehutano achaita musangano wekutevera kuti akurukure mhedzisiro uye zvinoreva hutano hwako. Vachatsanangura kana mazinga ako ekuwedzera hormone akajairika kana kana kumwe kuongorora kana kurapwa kungadiwa.

Kana mhedzisiro ichiratidza kushomeka kwehomoni yekukura, chiremba wako achakurukura sarudzo dzekurapa uye matanho anotevera. Kana mhedzisiro iri yakanaka, vachakubatsira kuongorora zvimwe zvinogona kukonzera zviratidzo zvako.

Muedzo weMacimorelin Wakarurama Sei?

Muedzo we macimorelin wakarurama zvikuru pakuongorora kushomeka kwehomoni yekukura muvanhu vakuru. Zvidzidzo zvekurapa zvinoratidza kuti inonyatsoziva mamiriro acho muzviitiko zvinenge 92-96%.

Muedzo uyu une hunyanzvi hwepamusoro (unobata vanhu vazhinji vane kushomeka kwehomoni yekukura) uye hunyanzvi hwepamusoro (haiongorori zvisizvo vanhu vasina mamiriro acho ezvinhu). Izvi zvinoita kuti ive chishandiso chakavimbika chekuongorora.

Zvisinei, semumwe muedzo wekurapa, haisi 100% yakakwana. Chiremba wako anogona kukurudzira kumwe kuyedzwa kana kuongororwa kana zviratidzo zvako zvisingaenderani nemhedzisiro yemuedzo wako, kana kana vachida rumwe ruzivo kuti vaite kuongororwa kwakakwana.