Chii chinonzi Margetuximab-cmkb: Kushandiswa, Mishonga, Migumisiro, nezvimwe

Margetuximab-cmkb mushonga wekenza unotarirwa unoshanda nekubatsira immune system yako kurwisa mhando dzakasiyana dzekenza yemazamu. Mushonga uyu unopiwa nemishonga ndewe kirasi inonzi monoclonal antibodies, iyo yakagadzirirwa kubatana nemaseru ekenza uye kuamaka kuti aparadzwe nekudzivirirwa kwemuviri wako.

Ungave uri kuverenga nezve mushonga uyu nekuti iwe kana mumwe munhu waunoda akawanikwa aine HER2-positive breast cancer. Kunyangwe kudzidza nezvekurapa kenza kunogona kunzwa kusinganzwisisike, kunzwisisa sarudzo dzako kunogona kukubatsira kuti unzwe wakagadzirira uye wakavimbika murwendo rwako rwekutarisirwa.

Chii chinonzi Margetuximab-cmkb?

Margetuximab-cmkb imuviri wakagadzirwa murabhoritari unotarisa protein chaiyo inonzi HER2 inowanikwa pamaseru ekenza yemazamu. Funga nezvazvo semutsvaki akatungamirirwa anotsvaga uye anobatana nemaseru ekenza, obva atumira chiratidzo kune yako immune system kuti ivarwise.

Mushonga uyu wakagadzirirwa zvakananga vanhu vane HER2-positive metastatic breast cancer. Chikamu che

Chiremba wako anowanzo kuraira mushonga uyu kana wakatotanga kuyedza mamwe marapirwo anotariswa HER2 akadai se trastuzumab (Herceptin) uye pertuzumab (Perjeta). Kazhinji inoshandiswa pamwe chete nemishonga yekemotheraphy kuti iite nzira yekurapa yakazara.

Mushonga uyu unobvumirwa zvakananga mumamiriro ezvinhu apo kenza yakafambira mberi pasinei nemishonga yapfuura. Chikwata chako chekuchengetedza hutano chichaedza maseru ako ekenza kuti aone kana aine protein yeHER2 vasati vatanga kurapwa uku, sezvo isingashande kune kenza yeHER2-negative.

Margetuximab-cmkb Inoshanda Sei?

Margetuximab-cmkb inoshanda nekubatanidza kune protein yeHER2 pamaseru ekenza uye kukoka immune system yako kuti ibatsire kuaparadza. Uyu mushonga wakasimba zvishoma wakagadzirirwa kushanda zviri nani pane mamwe marapirwo ekare anotariswa HER2.

Kana mushonga wabatanidzwa neprotein yeHER2, unovharisa zviratidzo zvinobatsira maseru ekenza kukura nekukwana. Panguva imwecheteyo, inoita sebhekeni, ichidaidza maseru eimmune kunzvimbo iyoyo kuti arwise maseru ekenza akamarkwa.

Chinoita kuti mushonga uyu usiyane nemishonga yekare inotariswa HER2 ndeyekuti yakagadzirwa kuti ishande zviri nani nerudzi rwakati rwemasero eimmune. Iyi yakawedzera kubatana inogona kubatsira immune system yako kuita mhinduro yakasimba pamaseru ekenza.

Ndingatora Sei Margetuximab-cmkb?

Margetuximab-cmkb inopiwa se intravenous (IV) infusion zvakananga muropa rako panzvimbo yekurapa kenza kana muchipatara. Hauzotori mushonga uyu kumba, sezvo uchida kutariswa zvakanyanya uye midziyo yakakosha.

Infusion yako yekutanga inowanzo tora maminitsi anenge 120, nepo kurapwa kunotevera kunowanzo tora maminitsi anenge 30. Chikwata chako chekuchengetedza hutano chichakutarisa zvakanyanya panguva ye infusion yega yega uye kwenguva yakati wandei mushure meizvozvo kuti chitarise chero maitiro ekukasira.

Haufaniri kudzivisa chikafu kana zvinwiwa musati mapihwa mushonga wenyu, asi zvinowanzoita kuti zvibatsire kudya chikafu chakareruka musati maitwa kuti mudzivise kusvotwa. Vamwe vanhu vanowana zvichivabatsira kuuya nebhuku, piritsi, kana mimhanzi kuti vabatsire kupfuudza nguva panguva yekupinza mushonga.

Chikwata chenyu chekurapa chichakupai mishonga musati mapihwa mushonga wega wega kuti ibatsire kudzivisa maitiro ekurwara. Mishonga iyi inogona kusanganisira antihistamines, steroids, kana zvinoderedza fivha, uye chikamu chakajairika chekufambiswa kwemushonga.

Ndingatora Margetuximab-cmkb kwenguva yakareba sei?

Kureba kwemushonga we margetuximab-cmkb kunosiyana kubva kumunhu nemunhu uye kunoenderana nekuti kenza yako inopindura sei kumushonga. Vanhu vazhinji vanogamuchira mishonga mumasvondo matatu ega ega, uye mucharamba muchiita chero bedzi mushonga uchibatsira kudzora kenza yenyu uye muchiutambira zvakanaka.

Chiremba wenyu achatarisa kufambira mberi kwenyu nguva dzose kuburikidza nekutarisa mifananidzo, bvunzo dzeropa, uye bvunzo dzemuviri. Kana kenza yenyu ikamira kupindura kumushonga kana kana mukawana matambudziko akakomba, chikwata chenyu chekuchengetedza hutano chichakurukura dzimwe sarudzo nemi.

Vamwe vanhu vanogona kugamuchira mushonga uyu kwemwedzi yakawanda kana kunyange makore, nepo vamwe vachigona kuchinjira kune mimwe mishonga nekukurumidza. Chinhu chakakosha kuwana chiyero chakakodzera pakati pekudzora kenza yenyu uye kuchengetedza hupenyu hwenyu hwakanaka.

Ndezvipi Zvakaipa zveMargetuximab-cmkb?

Semishonga yese yekenza, margetuximab-cmkb inogona kukonzera matambudziko, kunyangwe kwete munhu wese anoawana. Matambudziko mazhinji anogona kubatwa nekuchengetwa kwakakodzera uye kutariswa kubva kuchikwata chenyu chekuchengetedza hutano.

Heano matambudziko anowanzoitika aunogona kuwana panguva yemushonga:

• Kuneta uye kunzwa kuneta kupfuura zvakajairika
• Kusvotwa uye dzimwe nguva kurutsa
• Manyoka kana shanduko mumafambiro ematumbo
• Kuderera kwechido chekudya
• Kutemwa nemusoro
• Kurwadziwa kwemhasuru kana majoini
• Maitiro ekupinza semuenzaniso fivha, kutonhora, kana rash panguva yekurapa
• Kuverengwa kwakaderera kwemasero machena eropa, izvo zvinogona kuwedzera njodzi yekutapukirwa

Izvi zvinowanzoitika zvinokonzeresa zvinowanzoita zvinyoro kusvika pakati nepakati uye zvinowanzoita nani sezvo muviri wako uchigadzirisa kumushonga. Chikwata chako chekuchengeta chine nzira zhinji dzekubatsira kubata izvi zviratidzo uye kukuchengeta wakasununguka.

Nepo zvisingawanzoitiki, kune zvimwe zvinokonzera zvakakomba zvinoda kutariswa kwekurapa nekukurumidza:

• Matambudziko emoyo, kusanganisira mhasuru yemoyo yakashatiswa kana kurova kwemoyo kusingaite
• Maitiro akakomba ekuita allergic ane matambudziko ekufema kana kuzvimba
• Zvirwere zvakakomba nekuda kwekutapukirwa kwakaderera
• Matambudziko emapapu kana matambudziko ekufema
• Manyoka akakomba asingapinduri kurapwa
• Zviratidzo zve tumor lysis syndrome, uko masero ekenza anoputsika nekukurumidza

Chikwata chako chehutano chichakutarisa zvakanyanya kune izvi zvinokanganisa zvakakomba kuburikidza nekuyedzwa kwenguva dzose kwebasa remoyo, basa reropa, uye bvunzo dzemuviri. Vanhu vazhinji vanogona kuramba vachirapwa zvakachengeteka nekutarisa kwakakodzera uye kutarisirwa kunotsigira.

Ndiani Asingafaniri Kutora Margetuximab-cmkb?

Margetuximab-cmkb haikodzeri munhu wese, uye chiremba wako achanyatsoongorora kana zvakakunakira iwe. Mushonga uyu wakagadzirirwa zvakananga HER2-positive cancer, saka haizobatsiri kana kenza yako isina protein iyi.

Haufanire kugamuchira mushonga uyu kana wakambove nemaitiro akakomba ekuita allergic ku margetuximab-cmkb kana chero chimwe chezvinhu zvayo kare. Chiremba wako achanyatso funga nezvehutano hwako hwese uye chero mamwe mamiriro ezvinhu aunogona kunge uine.

Vanhu vane zvirwere zvemtima zvinogona kuda kuongororwa zvakanyanya kana vangave vasiri vakakodzera kurapwa uku. Chikwata chako chekuchengetwa kwehutano chichaongorora kushanda kwemoyo wako usati watanga kurapwa uye chichauongorora nguva dzose mukati mekutarisirwa kwako.

Kana uri nepamuviri kana kuyamwisa, mushonga uyu haukurudzirwi sezvo ungakuvadza mwana wako. Chiremba wako achakurukura nzira dzinoshanda dzekudzivirira pamuviri kana uri pazera rekubereka, sezvo uchizofanira kudzivirira pamuviri panguva yekurapwa uye kwemwedzi yakati wandei mushure.

Zita reBrand reMargetuximab-cmkb

Margetuximab-cmkb inotengeswa pasi pezita rebrand rekuti Margenza. Zita rebrand iri ndiro raungangozviona pane chirongwa chako chekurapwa uye magwaro einishuwarenzi.

Mishonga iyi inogadzirwa neMacroGenics uye yakatenderwa neFDA muna 2020. Paunenge uchikurukura kurapwa kwako nechikwata chako chekuchengetwa kwehutano, vanogona kuita kuti vataure nezvazvo nezita re generic rekuti margetuximab-cmkb kana zita rebrand rekuti Margenza.

Zvimwe Zvingashandiswa panzvimbo peMargetuximab-cmkb

Kana margetuximab-cmkb isiri yakakunakira kana ikamira kushanda nemazvo, pane dzimwe nzira dzekurapa dzinowanikwa dzekenza yemazamu yeHER2-positive. Oncologist wako achashanda newe kuti awane imwe nzira yakanakisa zvichienderana nemamiriro ako chaiwo.

Zvimwe zvinodhaka zvakanangana neHER2 zvinosanganisira trastuzumab (Herceptin), pertuzumab (Perjeta), uye trastuzumab emtansine (Kadcyla). Imwe neimwe yeizvi inoshanda zvishoma zvakasiyana uye inogona kunge yakakodzera zvichienderana nekurapwa kwako kwakapfuura uye mamiriro ako ehutano azvino.

Zvimwe zvingasarudzwa zvitsva zvinosanganisira tucatinib (Tukysa) uye neratinib (Nerlynx), izvo zvinodhaka zvinotorwa nemuromo zvinogona kutorwa kumba. Chiremba wako anogonawo kufunga nezvekusanganiswa kwemishonga iyi kana kuibatanidza nemimwe mishonga yekemotheraphy.

Sarudzo yekurapa kwakasiyana inoenderana nezvinhu zvakawanda, kusanganisira mishonga yawakamboedza, nzira yakapindura nayo kenza yako, uye hutano hwako hwese. Chikwata chako chekuchengetwa kwehutano chichakutungamira kuburikidza nezvisarudzo izvi kana zvichidikanwa.

Ko Margetuximab-cmkb Zviri Nani Kudarika Trastuzumab?

Margetuximab-cmkb yakagadzirirwa kuti ive inoshanda zvakanyanya kudarika trastuzumab (Herceptin) kune vamwe vanhu vane gomarara remazamu reHER2-positive. Zvidzidzo zvekiriniki zvakaratidza kuti zvinogona kupa mhedzisiro iri nani kune vamwe varwere, kunyanya avo vane hunhu hwemajini chaiwo.

Chinhu chikuru chinobatsira che margetuximab-cmkb ndechekuti yakagadzirwa kuti ishande zviri nani nehutachiona hwako hwezvirwere hwekurwisa gomarara. Mhinduro iyi yakawedzerwa yehutachiona inogona kubatsira kuti ive inoshanda zvakanyanya kudarika trastuzumab mune dzimwe nguva.

Zvisinei, "zviri nani" zvinoenderana nemamiriro ako ega. Trastuzumab yakashandiswa zvinobudirira kwemakore mazhinji uye ine yakanyatsojeka kuchengeteka. Chiremba wako achafunga nezvehunhu hwako hwegomarara, kurapwa kwakapfuura, uye hutano hwese paachifunga kuti mushonga upi wakanakira iwe.

Mishonga yese miviri ine maitiro akafanana emhedzisiro, kunyangwe mhinduro dzega dzichigona kusiyana. Sarudzo pakati pavo inowanzouya panguva yerwendo rwako rwekurapa uye kuti gomarara rako rakaita sei kumishonga yapfuura.

Mibvunzo Inowanzo Bvunzwa Nezve Margetuximab-cmkb

Q1. Ko Margetuximab-cmkb Yakachengeteka Kune Vanhu vane Chirwere chemoyo?

Margetuximab-cmkb inogona kukanganisa basa remoyo, saka vanhu vane chirwere chemoyo vanoda kunyatsoongororwa. Chiremba wako achaongorora hutano hwemoyo wako usati watanga kurapwa uye anogona kuraira echocardiogram kana mamwe bvunzo dzebasa remoyo.

Kana uine matambudziko emoyo akapfava, unogona kunge uchiri kukwanisa kugamuchira mushonga uyu nekunyatsoongororwa. Zvisinei, vanhu vane kukundikana kwemoyo kwakanyanya kana kukanganiswa kwakakosha kwemoyo vangangoda kufunga nezveimwe mishonga. Chiremba wako wemoyo uye oncologist vachashanda pamwechete kuti vaone nzira yakachengeteka yemamiriro ako chaiwo.

Q2. Ndingaita Sei Kana Ndikakanganwa Dose ye Margetuximab-cmkb?

Sezvo margetuximab-cmkb ichipiwa se infusion panzvimbo yekurapa, hauzokwanisi kukanganwa dose kumba. Zvisinei, kana uchida kuronga zvakare musangano, taura nechikwata chako chehutano nekukurumidza sezvinobvira kuti uronge nguva itsva yekurapa.

Zvakakosha kuedza kuramba uri pachirongwa nekurapwa kwako, sezvo dosing inobatsira kuchengetedza kushanda kwemushonga. Chikwata chako chinogona kushanda newe kuti uwane nguva dzemusangano dzinokodzera chirongwa chako uye kukubatsira kuchengetedza nguva dzose dzekurapa.

Q3. Ndingaita Sei Kana Ndine Reaction Panguva yeInfusion Yangu?

Kana ukaona chero zviratidzo zvisingawanzoitiki panguva ye infusion yako, zvakadai sekufema kwakaoma, kuoma pachipfuva, rash, kana kutonhora kwakanyanya, zivisa chikwata chako chehutano nekukurumidza. Vakadzidziswa kubata infusion reactions uye vane mishonga iripo yekuvabata nekukurumidza.

Mazhinji infusion reactions akapfava uye anogona kubatwa nekumhanyisa infusion rate kana kupa mamwe pre-medications. Chikwata chako chichakutarisa zvakanyanya panguva yekurapa kwega kwega uye chinogona kugadzirisa infusion speed kana kumisa kurapwa kana zvichidikanwa.

Q4. Ndingamira Rini Kutora Margetuximab-cmkb?

Ucharamba uchitora margetuximab-cmkb chero ichibatsira kudzora kenza yako uye uchigamuchira zvakanaka. Chiremba wako achatarisa nguva dzose mhinduro yako yekurapa kuburikidza nekutarisa uye bvunzo dzeropa, uye achakurukura chero shanduko muchirongwa chako chekurapa newe.

Usambomira mushonga uyu wega, kunyangwe uchinzwa zviri nani kana uchiona side effects. Chikwata chako chehutano chinogona kubatsira kubata side effects uye chichaita chero kugadzirisa kunodiwa kuchirongwa chako chekurapa zvichibva pamhinduro yako yemunhu uye zvaunoda.

Q5. Ndingatora Mimwe Mishonga Ndiri Kugamuchira Margetuximab-cmkb?

Kazhinji unogona kuramba uchitora mishonga yako yakajairika paunenge uchigamuchira margetuximab-cmkb, asi zvakakosha kuti ukurukure mishonga yako yese nechikwata chako chehutano. Izvi zvinosanganisira mishonga inopiwa nachiremba, mishonga inotengwa pasina chiremba, mavitamini, uye zvinowedzera zvemishonga yemakwenzi.

Mimwe mishonga inogona kukanganisa kurapwa kwako gomarara kana kukanganisa nzira iyo muviri wako unogadzirisa nayo mushonga. Chiremba wako kana muzvinamutsi anogona kuongorora runyorwa rwako rwemishonga rwese uye kuita chero shanduko dzinodiwa kuti ave nechokwadi chekuti zvese zvinoshanda pamwechete zvakachengeteka.