Chii chinonzi Metformin: Zvazvinoshandiswa, Madosi, Mhedzisiro uye Zvimwe

Metformin mushonga unonyanya kunyorerwa unobatsira kuderedza mazinga eshuga yeropa muvanhu vane chirwere cheshuga che rudzi rwechipiri. Kazhinji ndiyo mushonga wekutanga vanachiremba vanokurudzira kana shanduko dzemararamiro dzega dzisingakwani kudzora shuga yeropa nemazvo. Mushonga uyu unononoka asi unoshanda wanga uchibatsira mamiriyoni evanhu kudzora chirwere chavo cheshuga kwemakumi emakore, uye unoonekwa semumwe wemishonga yakachengeteka yechirwere cheshuga iripo.

Chii chinonzi Metformin?

Metformin mushonga wechirwere cheshuga wemuromo uyo uri muboka remishonga inonzi biguanides. Imushonga unotorwa nemishonga unouya muchimiro chepiritsi uye wakagadzirirwa kutorwa nemuromo pamwe chete nezvokudya. Kusiyana nemimwe mishonga yechirwere cheshuga, metformin haimanikidzi pancreas yako kuti ibudise insulin yakawanda, izvo zvinoita kuti inyoro pamasisitimu ako echisikigo emuviri.

Mushonga uyu wanga uripo kubvira kuma1950 uye une rekodhi yakanaka yekuchengeteka. Inowanikwa mune zvese zvinoburitswa nekukurumidza uye mafomula akawedzerwa, zvichikupa iwe nachiremba wako kuchinjika mukutsvaga nzira yakakodzera yezuva rako nezuva.

Chii chinonzi Metformin chinoshandiswa?

Metformin inonyanya kushandiswa kurapa chirwere cheshuga che rudzi rwechipiri, asi inogonawo kubatsira nezvimwe zvehutano. Kune chirwere cheshuga, kazhinji ndiyo yekutanga sarudzo nekuti inoshanda uye inotsungirirwa zvakanaka nevanhu vazhinji. Chiremba wako angangokunyora wega kana kuibatanidza nemimwe mishonga yechirwere cheshuga kuti uwane kutonga kwakanaka kweshuga yeropa.

Kunze kwechirwere cheshuga, vanachiremba dzimwe nguva vanonyora metformin ye polycystic ovary syndrome (PCOS) kubatsira kudzora kutenderera kwemwedzi uye kuvandudza insulin sensitivity. Vamwe vanopa hutano vanoshandisawo kubatsira kudzivirira chirwere cheshuga che rudzi rwechipiri muvanhu vari panjodzi huru yekuvandudza mamiriro acho ezvinhu.

Mune zvimwe zviitiko, metformin inogona kufungwa nezvekudzora uremu muvanhu vane insulin resistance, kunyangwe izvi zvakajairika kushandiswa kunze kwechinyorwa chinoda kutariswa kwechiremba kwakanyatsojeka.

Metformin Inoshanda Sei?

Metformin inoshanda munzira dzakawanda dzakapfava kubatsira muviri wako kudzora shuga yeropa zvakanyanya. Inonyanya kuderedza huwandu hweglucose rinogadzirwa chiropa chako, kunyanya panguva dzokutsanya semuenzaniso husiku. Izvi zvinobatsira kudzivirira kukwira kweshuga yeropa mangwanani ayo vanhu vazhinji vane chirwere cheshuga vanosangana nacho.

Mishonga iyi inoitawo kuti maseru ako emhasuru ave sensitive ku insulin, zvinoreva kuti muviri wako unogona kushandisa insulin yaunogadzira zvakanyanya. Funga nezvazvo sekubatsira kuvhura mikova yemasero ako kuitira kuti glucose ipinde nyore nyore.

Mukuwedzera, metformin inononotsa zvishoma kuti matumbu ako anokurumidza sei kutora glucose kubva muzvokudya. Izvi zvinogadzira kukwira zvishoma nezvishoma kweshuga yeropa mushure mekudya pane kukwira kwakanyanya. Sezvo mishonga yechirwere cheshuga ichienda, metformin inofungidzirwa kuti ine simba repakati, ichishanda zvishoma nezvishoma pane kukonzera shanduko dzakanyanya.

Ndingatora Sei Metformin?

Tora metformin sezvinorayirwa nachiremba wako, kazhinji uchiitora nezvokudya kuderedza kusagadzikana mudumbu. Vanhu vazhinji vanotanga nedosi yakaderera iyo inowedzera zvishoma nezvishoma kwemavhiki akati wandei, ichipa muviri wako nguva yekujairana zvakanaka. Iyi nzira inobatsira kuderedza mhedzisiro yezvinhu uye inobvumira chiremba wako kuwana dosi yakakunakira.

Medza mahwendefa ese nemvura yakawanda. Kana iwe uchitora vhezheni yakawedzerwa, usapwanye, kutsenga, kana kuputsa mahwendefa sezvo izvi zvinogona kukanganisa nzira iyo mushonga unoburitswa mumuviri wako.

Kutora metformin nezvokudya kwakakosha nezvikonzero zviviri. Chekutanga, zvinoderedza zvakanyanya mukana wekusagadzikana mudumbu, kusvotwa, kana manyoka. Chechipiri, zvinobatsira muviri wako kutora mushonga zvakanyanya. Haufaniri kudya zvokudya zvakawanda, asi kuva nezvimwe zvokudya mudumbu mako kunoita mutsauko chaiwo mukuti uchashivirira sei mushonga.

Edza mishonga yako panguva imwe chete zuva rega rega kuti uchengetedze mazinga akagadzikana mumuviri wako. Kana uchitora kaviri pazuva, kupatsanura mishonga maawa gumi nemaviri kunoshanda zvakanaka kune vanhu vazhinji.

Ndingatora Metformin Kwenguva Yakareba Sei?

Vanhu vazhinji vane chirwere cheshuga che mhando 2 vanotora metformin kwenguva refu, kazhinji kwemakore mazhinji kana kunyange hupenyu hwese. Izvi hazvisi nekuti unovimba nayo, asi nekuti chirwere cheshuga che mhando 2 chirwere chisingaperi chinoda kurapwa nguva dzose. Metformin inobatsira kuchengetedza shuga yeropa rako mumwero wakanaka chero uchitora.

Chiremba wako achatarisa nguva dzose mazinga eshuga yeropa rako, kushanda kwematsvo, uye hutano hwese kuti ave nechokwadi chekuti metformin inoenderera mberi kuve sarudzo yakakodzera kwauri. Vamwe vanhu vanowana kuti kutonga kweshuga yeropa ravo kunovandudzika zvakanyanya nekuchinja mararamiro, uye chiremba wavo angachinja kana kuderedza mishonga yavo zvinoenderana.

Kureba kwekushandisa kunoenderana nemamiriro ako ega. Zvinhu zvakaita sekuti shuga yeropa rako inotungamirirwa sei, chero mhedzisiro yaunowana, shanduko muhutano hwako, uye mhinduro yako kune shanduko dzemararamiro zvese zvinotamba basa mukuziva kuti uchada kutora metformin kwenguva yakareba sei.

Usambomira kutora metformin kamwe kamwe usina kutaura nechiremba wako kutanga, sezvo izvi zvinogona kukonzera kuti shuga yeropa rako ikwire nekukurumidza uye zvinogona kutungamira kumatambudziko.

Ndezvipi Zvakaipa zveMetformin?

Metformin inowanzotsungirirwa zvakanaka, asi semishonga yese, inogona kukonzera mhedzisiro kune vamwe vanhu. Mashoko akanaka ndewekuti mhedzisiro yakawanda yakapfava uye inowanzoita nani sezvo muviri wako uchigadzirisa kumishonga mumavhiki mashoma ekutanga.

Heano mhedzisiro yakajairika yaungasangana nayo, kunyanya paunotanga metformin kana kuwedzera muyero wako:

• Kusvotwa uye dumbu kusagadzikana
• Diarhea kana zvigaro zvakasununguka
• Gasi uye kuzvimba
• Kuravira kwesimbi mumuromo mako
• Kurasikirwa nechido
• Kukramba mudumbu

Mhedzisiro iyi yekudya inowanzo nyangarika mukati memavhiki mashoma sezvo muviri wako uchigadzirisa. Kutora metformin pamwe chete nechikafu uye kutanga nedosi yakaderera kunogona kubatsira kuderedza nyaya idzi zvakanyanya.

Mhedzisiro isingawanzoitiki asi yakakomba inosanganisira kushomeka kwevhitamini B12 nekushandiswa kwenguva refu, ndosaka chiremba wako angatarisa mazinga ako eB12 nguva nenguva. Vamwe vanhu vanosanganawo nekuneta kana kusava nesimba, kunyanya mumavhiki mashoma ekutanga ekurapa.

Kazhinji, metformin inogona kukonzera mamiriro akakomba anonzi lactic acidosis, iyo inosanganisira kuwanda kwe lactic acid muropa. Izvi hazviwanzoitiki muvanhu vane basa reitsvo rakajairika, asi ndosaka chiremba wako achitarisa hutano hweitsvo dzako nguva dzose. Zviratidzo zvinosanganisira kurwadziwa kwemhasuru kusinganzwisisike, kuoma kufema, kurwadziwa mudumbu, dzungu, kana kunzwa kusava nesimba kana kuneta.

Ndiani Asingafaniri Kutora Metformin?

Metformin haina kukodzera munhu wese, uye chiremba wako achanyatso funga nezve nhoroondo yako yehutano vasati vanyora. Mushonga unonyanya kusefa kuburikidza neitsvo dzako, saka vanhu vane chirwere cheitsvo chakakomba havawanzo tora metformin zvakachengeteka.

Chiremba wako angangodzivisa kunyora metformin kana uine chirwere cheitsvo chakakomba, matambudziko echiropa, kana nhoroondo ye lactic acidosis. Vanhu vane mamwe mamiriro emoyo, kunyanya ayo anosanganisira mazinga eokisijeni akaderedzwa, vanogonawo kuda mamwe marapirwo.

Kana iwe wakarongerwa kuvhiyiwa kana mamwe maitiro ekurapa anosanganisira ruvara rwekupesana, chiremba wako angamisa zvishoma metformin yako. Ichi chiyero chekuchengetedza kuchengetedza itsvo dzako panguva yemaitiro aya.

Vanhu vane chirwere cheshuga chetype 1 havawanzo shandisa metformin sekurapa kwavo kwekutanga, kunyangwe dzimwe nguva ichiwedzerwa kurapa kwe insulin mumamiriro akasiyana. Vakadzi vane pamuviri vane chirwere cheshuga vanowanzo shandisa insulin panzvimbo ye metformin, kunyangwe izvi zvichisiyana nemamiriro emunhu uye kutonga kwekurapa.

Chiremba wako achafungawo nezve zera rako, sezvo vanhu vakuru vangada kuongororwa zvakanyanya kana kugadzirisa muyero wemishonga nekuda kwekuchinja kwebasa reitsvo nekufamba kwenguva.

Mazita emhando yeMetformin

Metformin inowanikwa pasi pemazita akati wandei emhando, kunyangwe vhezheni ye generic ichishanda zvakanyanya uye inodhura zvakanyanya. Mazita emhando anowanzozivikanwa anosanganisira Glucophage yemahwendefa ekuburitswa nekukasira uye Glucophage XR yemafomu ekuburitswa kwenguva yakareba.

Mamwe mazita emhando yaungasangana nawo anosanganisira Fortamet, Glumetza, uye Riomet (fomu remvura). Kune zvakare mishonga inosanganiswa ine metformin pamwe chete nemimwe mishonga yechirwere cheshuga, senge Janumet (metformin pamwe ne sitagliptin) uye Glucovance (metformin pamwe ne glyburide).

Kunyangwe iwe uchitora zita remhando kana generic metformin, chinhu chinoshanda uye kushanda zvakafanana. Chirongwa chako cheinishuwarenzi chingasarudza chimwe pane chimwe, saka zvakakosha kukurukura sarudzo nachiremba wako nemupharmacist kuti uwane sarudzo inodhura kwauri.

Zvimwe zvingashandiswa panzvimbo peMetformin

Kana metformin isiri iyo yakakunakira kana isingape kutonga kwakakwana kweshuga yeropa, mishonga yakati wandei inowanikwa. Chiremba wako angangofunga sulfonylureas senge glyburide kana glipizide, iyo inoshanda nekukurudzira pancreas yako kuti ibudise insulin yakawanda.

Makirasi emishonga matsva anosanganisira SGLT2 inhibitors (senge empagliflozin kana canagliflozin) iyo inobatsira itsvo dzako kubvisa glucose yakawandisa kuburikidza neweti. DPP-4 inhibitors senge sitagliptin inoshanda nekuwedzera kugadzirwa kwe insulin kana shuga yeropa yakakwira uye kuderedza kugadzirwa kwe glucose kana iri yakajairika.

Kune vanhu vanoda kurapwa kwakanyanya, GLP-1 receptor agonists senge semaglutide kana liraglutide inogona kushanda zvakanyanya. Mishonga iyi haingoderedzi shuga yeropa chete asi inowanzo kubatsirawo mukurasikirwa uremu.

Mune dzimwe nguva, kurapwa ne insulin kungave kwakakosha, kungava kwoga kana pamwe chete nemishonga inotorwa nemuromo. Chiremba wako achashanda newe kuti awane musanganiswa wakanaka wekurapa zvichienderana nezvido zvako, hutano hwako, uye zvinangwa zvekurapa.

Ko Metformin iri nani kupfuura mimwe mishonga ye diabetes here?

Metformin inowanzofungidzirwa seyakajairika yekutanga kurapa kwechirwere cheshuga che mhando 2, uye pane zvikonzero zvakanaka zveizvi. Inoshanda pakudzikisa shuga yeropa, ine rekodhi refu yekuchengeteka, uye kazhinji haina kukonzera kuwedzera uremu kana zviitiko zve shuga yakaderera yeropa kana ichishandiswa yega.

Kana ichienzaniswa ne sulfonylureas, metformin haina kukonzera hypoglycemia (shuga yeropa yakaderera zvakanyanya) uye kuwedzera uremu. Kusiyana nemimwe mishonga mitsva ye diabetes, metformin inodhurawo uye ine makumi emakore ekutsvagurudza ichitsigira kushandiswa kwayo.

Zvisinei, "zvirinani" zvinoenderana nemamiriro ako. Vamwe vanhu vanogona kuwana kutonga kwakanaka kweshuga yeropa nemimwe mishonga, nepo vamwe vachigona kusangana nemigumisiro mishoma nemimwe mishonga. Mishonga mitsva seGLP-1 agonists ingave sarudzo dziri nani kune vanhu vanodawo kurasikirwa nehuremu.

Mishonga yakanaka ye diabetes kwauri ndiyo inodzora shuga yako yeropa zvakanaka ichikonzera migumisiro mishoma uye ichikodzera mararamiro ako. Chiremba wako achafunga nezvezvinhu zvakaita semamwe mamiriro ako ehutano, mishonga yauri kutora, uye zvinangwa zvako zvekuzvirapa paunenge uchiita mazano.

Mibvunzo Inowanzo Bvunzwa Nezve Metformin

Ko Metformin yakachengeteka here kune chirwere chemoyo?

Hongu, metformin inowanzova yakachengeteka kune vanhu vane chirwere chemoyo uye inogona kunyange kupa mamwe mabhenefiti emoyo. Tsvakurudzo inoratidza kuti metformin inogona kubatsira kuderedza njodzi yekurwiswa kwemoyo uye sitiroko muvanhu vane chirwere cheshuga, zvichiita kuti ive sarudzo yakanaka kune avo vane mamiriro emoyo aripo.

Asi, chiremba wako achanyatsoongorora mamiriro emoyo wako asati anyora metformin. Vanhu vane kutadza kwemoyo kwakanyanya kana mamiriro anokanganisa mazinga eokisijeni muropa vangangoda mamwe marapirwo kana kuongororwa pedyo.

Ndingaita Sei Kana Ndakatora Metformin Yakawanda Netsaona?

Kana netsaona ukatora metformin yakawanda kupfuura yakanyorwa, taura nachiremba wako kana muzvinemishonga nekukasira kuti uwane gwara. Kutora kaviri dose dzimwe nguva hazviwanzo kuva nenjodzi, asi kutora yakawanda zvakanyanya kupfuura yakanyorwa kungawedzera njodzi yako yezvinhu zvinokonzeresa, kunyanya lactic acidosis.

Tarisa zviratidzo zvakaita senausea yakanyanya, kurutsa, kurwadziwa mudumbu, kurwadziwa kwemhasuru, kuoma kufema, kana kuneta kusinganzwisisike. Kana ukaona chero zviratidzo izvi mushure mekutora metformin yakawanda, tsvaga rubatsiro rwekurapa nekukasira.

Kuti udzivise overdoses netsaona, funga kushandisa murongi wemapiritsi uye kumisa zviyeuchidzo pafoni yako. Kana usina chokwadi chekuti wakatora dose yako, zvinowanzova zvakachengeteka kusvetuka dose iyoyo pane kuisa njodzi yekuitora kaviri.

Ndingaita Sei Kana Ndikarasikirwa neDose yeMetformin?

Kana ukakanganwa dose ye metformin, itore paunorangarira, asi chete kana iri nechikafu kana snack. Kana yava nguva yechikamu chako chinotevera, svetuka dose yakarasika uye uenderere mberi nehurongwa hwako hwenguva dzose.

Usambofa wakatora dose mbiri panguva imwe chete kuti ugadzirise dose yakarasika, sezvo izvi zvichawedzera njodzi yako yezvinhu zvinokonzeresa. Kana iwe uchikanganwa dose kazhinji, taura nachiremba wako nezve nzira dzekukubatsira kurangarira, sekuzvitora panguva imwe chete nezvimwe zviitiko zvemazuva ese.

Kukanganwa dose dzimwe nguva hakuzokonzerese matambudziko nekukasira, asi kugara uchikanganwa dose kunogona kutungamira mukudzora shuga yeropa kwakashata nekufamba kwenguva.

Ndingamira Rini Kutora Metformin?

Hamufaniri kumbomira kutora metformin musina kumbotaura nachiremba wenyu kutanga. Vamwe vanhu vanogona kuderedza kana kumisa metformin kana vakarasikirwa uremu zvakanyanya, vachichinja mararamiro avo zvakanyanya, kana kana kutonga kwavo shuga yeropa kuchivandudzika zvakanyanya.

Chiremba wenyu achatarisa mazinga eshuga yeropa renyu, bvunzo dzeA1C, uye hutano hwese kuti aone kana uye rini zvichakodzera kugadzirisa mushonga wenyu. Vamwe vanhu vanowana kuti nekuchinja mararamiro avo zvakatsiga, vanogona kuderedza chiyero chavo kana kuchinjira kune imwe nzira yekurapa.

Rangarirai kuti chirwere cheshuga chekare 2 chirwere chinofambira mberi, uye kunyangwe mukamira metformin kwenguva pfupi, mungada kuitangazve kana kuyedza mamwe mishonga mune ramangwana sezvo mamiriro enyu achichinja.