Chii chinonzi Naldemedine: Zvazvinoshandiswa, Mishonga, Zvazvinokonzeresa uye Zvimwe

Naldemedine mushonga unopiwa nachiremba unobatsira kurapa kuvharika kwemudumbu kunokonzerwa nemishonga yekurwadziwa yeopioid. Kana uri kutora maopioid ekurwadziwa kusingaperi uye uchinetseka nekuzara mudumbu, naldemedine inoshanda nekudzivisa opioid receptors mumuviri wako wekugaya chikafu pasina kukanganisa kubatsira kurwadziwa. Iyi nzira yakatarwa inobvumira kufamba kwematumbo ako kudzokera kune yakajairika pateni apo mushonga wako wekurwadziwa unoramba uchishanda nemazvo.

Chii chinonzi Naldemedine?

Naldemedine ndeyemukirasi yemishonga inonzi opioid antagonists. Yakagadzirirwa kunyanya kurwisa mhedzisiro yekuvharika kwemudumbu yemishonga yeopioid pasina kukanganisa mabhenefiti avo ekubatsira kurwadziwa. Funga nezvayo seblocker inosarudzika inoshanda chete mudumbu rako.

Mishonga yakagadzirwa nekuti opioid-induced constipation inokanganisa vanenge vese vanotora opioid pain medications nguva dzose. Kusiyana nekuzara mudumbu kwenguva dzose, rudzi urwu haruwanzopinduri zvakanaka kumishonga yakajairika senge fiber supplements kana over-the-counter laxatives.

Chii chinonzi Naldemedine chinoshandiswa?

Naldemedine inorapa opioid-induced constipation muvanhu vakuru vane chronic non-cancer pain. Chiremba wako anowanzoikupa kana wanga uchitora opioid medications nguva dzose uye uchinetseka nekuzara mudumbu semugumisiro.

Mishonga iyi yakanyanya kuvanhu vane kuzara mudumbu kwavo kusina kuvandudzwa nemamwe marapirwo senge shanduko yezvokudya, kuwedzera kunwa mvura, kana over-the-counter laxatives. Zvakakosha kunzwisisa kuti naldemedine inoshanda chete pakuzara mudumbu kunokonzerwa nemaopioid, kwete mamwe marudzi ekuzara mudumbu.

Naldemedine inoshanda sei?

Naldemedine inoshanda nekudzivisa opioid receptors mumuviri wako wekugaya chikafu. Paunotora opioid pain medications, vanosungirira kune receptors mumuviri wako wese, kusanganisira mudumbu rako, izvo zvinononotsa kugaya uye zvinokonzera kuzara mudumbu.

Mishonga iyi inoshanda semukiyi unokwana mumareceptor iwayo mudumbu mako, ichidzivirira maopioids kubva pakubatanidzwa ipapo. Zvisinei, naldemedine haipindi muuropi hwako kana musana, saka haikanganisi kurapa kurwadziwa. Chiito ichi chisarudzo chinoita kuti ive mhinduro inoshanda yekuchengetedza manejimendi ekurwadziwa uku ichidzosa basa rakajairika remudumbu.

Ndinofanira Kutora Sei Naldemedine?

Tora naldemedine sezvinorairwa nachiremba wako, kazhinji kamwe chete pazuva uine kana usina chikafu. Madosi akajairika evakuru i0.2 mg (piritsi rimwe) rinotorwa panguva imwe chete zuva rega rega. Medza piritsi rose nemvura uye usapwanye, kuputsa, kana kutsenga.

Unogona kutora naldemedine nezvikafu kana ichikutsamwisa dumbu rako, kunyangwe chikafu chisinganyanyi kukanganisa mashandiro emushonga. Edza kugadzira tsika nekuitora panguva imwe chete zuva rega rega kuti ikubatsire kuyeuka uye kuchengetedza mazinga akagadzikana mumuviri wako.

Kana uine dambudziko rekumedza mapiritsi, taura nachiremba wako nezve dzimwe nzira. Usamira kutora mushonga wako weopioid pain usati watanga naldemedine kunze kwekunge chiremba wako akakuudza zvakananga kuti uite kudaro.

Ndinofanira Kutora Naldemedine Kwenguva Yakareba Sei?

Iwe unowanzo tora naldemedine kwenguva yakareba sezvaunotora mishonga yeopioid pain uye uchiona kuvharika. Vanhu vazhinji vanoenderera mberi vachiitora mukati memwaka wavo wekurapa opioid, uyo unogona kuva mavhiki, mwedzi, kana kwenguva refu zvichienderana nezvido zvako zvekurapa kurwadziwa.

Chiremba wako achatarisa mhinduro yako kumushonga uye anogona kugadzirisa chirongwa chako chekurapa zvichienderana nekuti chiri kushanda zvakanaka sei. Vamwe vanhu vanoona kuvandudzwa mukufamba kwavo kwematumbo mukati memazuva mashoma, nepo vamwe vangatora kusvika vhiki kuti vaone mabhenefiti akazara.

Usamira kutora naldemedine kamwe kamwe usina kutaura nachiremba wako kutanga. Kana uchida kumisa mushonga, chiremba wako achakutungamira kuburikidza nemaitiro uye achakurukura dzimwe nzira dzekurapa dzekugadzirisa opioid-induced constipation.

Ndezvipi Zvakaipa Zvinokonzerwa neNaldemedine?

Semishonga yese, naldemedine inogona kukonzera zvakaipa, kunyangwe kwete munhu wese anozviwana. Zvizhinji zvezvakaipa zviri nyoro uye zvinowanzoita nani sezvo muviri wako uchigadzirisa kumushonga.

Zvakanyanya kuwanda zvinogona kukonzerwa newe zvinosanganisira kurwadziwa mudumbu, manyoka, kusvotwa, uye gastroenteritis (zviratidzo zvakaita sefuruu yedumbu). Izvi zvinokanganisa zvekudya zvinonzwisisika zvichipiwa kuti mushonga unoshanda sei kudzorera basa rakajairika rematumbo.

Heano zvakanyanya kukonzerwa nezvakaipa zvekuziva nezvazvo:

• Kurwadziwa mudumbu kana kukramba
• Manyoka
• Kusvotwa
• Kurutsa
• Zviratidzo zveGastroenteritis

Zviratidzo izvi zvinowanzoitika kwenguva pfupi uye zvinyoro. Zvisinei, kana manyoka akava akakomba kana kuramba, taura nachiremba wako sezvo ungada kugadzirisa muyero wako kana kumisa mushonga kwenguva pfupi.

Zvisingawanzoitiki asi zvakanyanya kukomba zvinogona kuitika, kunyangwe zvichiwanzodiwa. Izvi zvinosanganisira kurwadziwa kwakanyanya mudumbu, zviratidzo zvekuvharika kwematumbo, kana maitiro ekuita allergic. Kana iwe ukaona kurwadziwa kwakanyanya mudumbu, kurutsa kunoramba kuripo, kana zviratidzo zvekuita allergic senge rash, kuoma kufema, kana kuzvimba, tsvaga rubatsiro rwekurapa nekukasira.

Ndiani Asingafaniri Kutora Naldemedine?

Naldemedine haikodzeri munhu wese. Haufaniri kutora mushonga uyu kana uine kuzivikanwa kwekuvharika kwematumbo kana kuvharika, sezvo zvingawedzera mamiriro aya.

Chiremba wako achanyatsoongorora nhoroondo yako yekurapa usati wanyora naldemedine. Vanhu vane mamiriro akati wandei ekugaya vanogona kuda kuongororwa kwakakosha kana vangave vasiri vakakodzera mushonga uyu.

Heano mamiriro anogona kukudzivisa kutora naldemedine:

• Kuzivikanwa kana kufungidzirwa kuvharika kwematumbo
• Matambudziko akakomba echiropa
• Allergy ku naldemedine kana zvinosanganiswa zvayo
• Zvimwe zvirwere zvekudya zvinokanganisa kufamba kwematumbo

Vakadzi vane pamuviri kana vanoyamwisa vanofanira kukurukura njodzi nemabhenefiti nachiremba wavo, sezvo kuchengeteka kwe naldemedine panguva yekuzvitakura nekuyamwisa kusati kwanyatsozivikanwa. Chiremba wako achayerera mabhenefiti anogona kuitika achienzanisa nenjodzi dzinogona kuitika.

Mazita eBrand eNaldemedine

Naldemedine inowanikwa pasi pezita rebrand rekuti Symproic muUnited States. Iyi ndiyo fomu yemushonga inonyanya kunyorerwa uye inouya mumahwendefa e0.2 mg.

Iyo generic vhezheni ye naldemedine inogona kuwanikwa mune ramangwana, asi parizvino, Symproic ndiyo zita rekutanga rebrand raunosangana naro. Nguva dzose shandisa mushonga chaiwo unonyorerwa nachiremba wako uye usatsive nemamwe mabhurendi pasina mvumo yechiremba.

Zvimwe Zvingashandiswa Panzvimbo peNaldemedine

Kana naldemedine isingashande zvakanaka kwauri kana kukonzera matambudziko, mishonga yakati wandei inogona kurapa kuvharika kwemudumbu kunokonzerwa neopioid. Chiremba wako angangofunga methylnaltrexone (Relistor) kana naloxegol (Movantik), iyo inoshanda zvakafanana nekudzivisa opioid receptors mudumbu.

Vamwe vanhu vanowana kubudirira nemalaxatives echinyakare senge polyethylene glycol (MiraLAX) kana stimulant laxatives, kunyangwe izvi zvichiwanzove zvisina kubudirira pakuvharika kwemudumbu kunokonzerwa neopioid. Chiremba wako angangakurudzirawo shanduko dzemararamiro senge kuwedzera kudya fiber, kuita maekisesaizi akawanda, uye kunwa mvura yakakwana senzira dzekutsigira.

Sarudzo yezvimwe zvingashandiswa zvinoenderana nemamiriro ako chaiwo, mamwe mishonga yaunotora, uye mhinduro yemuviri wako kumishonga yakasiyana. Usambofa wakachinja mishonga usati wambotaura nemupi wehutano wako kutanga.

Naldemedine iri Nani Pane Methylnaltrexone Here?

Ose ari maviri naldemedine uye methylnaltrexone anobudirira kurapa kuvharika kwemudumbu kunokonzerwa neopioid, asi ane zvakanakira zvakasiyana. Naldemedine inotorwa nemuromo kamwe chete pazuva, zvichiita kuti zvive nyore kune vanhu vazhinji, nepo methylnaltrexone inowanzo kupihwa sejojo.

Sarudzo pakati pemishonga iyi inowanzovimba nezvaunoda, mararamiro ako, uye kuti muviri wako unopindura sei kune imwe neimwe. Vamwe vanhu vanoda nyore nyore yepiritsi rezuva nezuva, nepo vamwe vangapindura zviri nani kune fomu rejekiseni.

Chiremba wako achafunga zvinhu zvakaita semimwe mishonga yaunotora, kushanda kwematsvo ako, uye zvaunoda iwe pachako paachasarudza kuti ndeipi sarudzo iri nani kwauri. Mishonga yese miviri ine mitengo yekushanda yakafanana, saka sarudzo inowanzouya pasi pekufunga kwechokwadi uye kupindura kwemunhu.

Mibvunzo Inowanzo Bvunzwa Pamusoro peNaldemedine

Naldemedine Yakachengeteka Kune Vanhu vane Chirwere cheItsvo Here?

Vanhu vane matambudziko ematsvo akapfava kusvika pakati nepakati vanowanzo tora naldemedine zvakachengeteka, asi chiremba wako angangoda kukutarisa zvakanyanya. Kana uine chirwere chakakomba cheitsvo, chiremba wako achanyatso funga nezve mabhenefiti nenjodzi usati anyora mushonga uyu.

Kushanda kwematsvo ako kunokanganisa kuti muviri wako unogadzirisa sei naldemedine, saka kugadzirisa muyero kungave kwakakosha. Nguva dzose zivisa chiremba wako nezve chero matambudziko ematsvo usati watanga mushonga uyu, uye enda kune ese akakurudzirwa ekutevera-up misangano yekutarisa.

Ndoitei kana ndikatora naldemedine yakawandisa netsaona?

Kana netsaona ukatora naldemedine yakawanda kupfuura yakanyorwa, taura nachiremba wako kana nzvimbo yekudzora chepfu nekukasira. Kutora zvakanyanya kunogona kukonzera manyoka akakomba, kupera mvura mumuviri, kana mamwe matambudziko akakomba ekugaya.

Usaedze kurapa overdose iwe pachako. Paunenge uchimirira mazano ekurapa, gara uine mvura yakakwana uye zvi tarise iwe pachako zviratidzo zvakaita sekurwadziwa mudumbu kwakanyanya, kurutsa kunoramba kuripo, kana zviratidzo zvekupera mvura mumuviri. Chengeta bhodhoro remushonga newe paunenge uchitsvaga rubatsiro rwekurapa kuitira kuti vanopa hutano vazive chaizvo zvawakatora uye yakawanda sei.

Ndoitei kana ndikakanganwa dose yeNaldemedine?

Kana ukakanganwa kutora mushonga we naldemedine, tora paunorangarira, kunze kwekunge yava nguva yekutora mushonga wako unotevera. Muchiitiko ichocho, rega kutora mushonga wakakanganwa wotora mushonga wako unotevera panguva yakajairika.

Usambofa wakatora mishonga miviri panguva imwe chete kuti uzadze mushonga wakakanganwa, sezvo izvi zvingawedzera njodzi yako yekuwana mhedzisiro. Kana uchikanganwa mishonga kakawanda, funga kuisa alarm yezuva nezuva kana kushandisa chirongwa chemishonga kuti ikubatsire kurangarira.

Ndingamira Rini Kutora Naldemedine?

Unogona kumira kutora naldemedine kana usisadi mishonga yekurwadziwa ye opioid kana chiremba wako akasarudza kuti hazvichadiwi. Vanhu vazhinji vanomisa naldemedine kana vapedza kurapwa kwavo kwe opioid kana kuchinjira kune kurapwa kwekurwadziwa kusiri kwe opioid.

Nguva dzose taura nachiremba wako usati wamisa naldemedine, kunyangwe ukanzwa zviri nani. Chiremba wako achafunga nezve chirongwa chako chekurapa kurwadziwa uye anogona kuda kukutarisa kuti uone kana zviratidzo zvekuvhara ura zvichidzoka usati wamisa zvachose mushonga.

Ndingatora Naldemedine pamwe chete nemamwe ma laxatives here?

Kazhinji, haufaniri kuda mamwe ma laxatives uchitora naldemedine, sezvo ichinyanya kurwisa kuvharika ura kunokonzerwa ne opioid. Zvisinei, chiremba wako anogona dzimwe nguva kukurudzira kusanganisa kurapwa kana uine zvimwe zvinokonzera kuvharika ura.

Usambofa wakawedzera mamwe ma laxatives kune yako routine usina kutanga wataura nachiremba wako, sezvo izvi zvingakonzera kufamba kwakanyanya kwematumbo kana mamwe matambudziko. Kana naldemedine yega isingapi rubatsiro rwakakwana, taura izvi nemupi wako wehutano pane kuzvirapa nemimwe mishonga.