Chii chinonzi Naloxone Nasal Spray: Zvinoshandiswa, Dosage, Side Effects uye Zvimwe

Naloxone nasal spray mushonga unoponesa hupenyu unogona kudzosa opioid overdoses mukati memaminitsi. Yakagadzirirwa kuve nyore zvakakwana kuti chero munhu aishandise panguva yekukurumidzira, kunyangwe vasina kudzidziswa kwekurapa.

Mushonga uyu unoshanda nekudzivisa opioid receptors muuropi hwako, zvichinyatso "kubvisa" zvinodhaka zvine njodzi zvakaita seheroin, fentanyl, kana marwadzo ekurapa. Funga nezvazvo sebhatani rekukurumidzira rinogona kudzosera mumwe munhu kubva kune overdose inogona kuuraya.

Chii chinonzi Naloxone Nasal Spray?

Naloxone nasal spray iopioid antagonist inouya mumudziyo wemhino wakagadzirirwa kushandiswa. Imushonga mumwe chete uyo vanopindura nekukurumidza vanoshandisa, asi vakaputirwa nenzira inoita kuti vawanikwe kumhuri, shamwari, uye nhengo dzemunharaunda.

Fomu remhino rinokosha nekuti haridi tsono kana kudzidziswa kwakakosha. Iwe unongobvisa chivharo, woisa mumhino dzemunhu, uye wotsikirira plunger zvakasimba. Mushonga unotora nekukurumidza kuburikidza nemashu emhino uye unopinda muropa mukati memaminitsi 2-3.

Mushonga uyu wakakosha zvekuti nyika zhinji zvino dzinobvumira makemisi kuti adzivise pasina mushonga. Inoonekwa sechishandiso chakakosha mukugadzirisa dambudziko reopioid rinokanganisa nharaunda munyika yose.

Chii chinonzi Naloxone Nasal Spray chinoshandiswa?

Naloxone nasal spray ine chinangwa chimwe chete: kudzosa opioid overdoses izvo zvingave zvakauraya. Inoshanda kurwisa marudzi ese eopioids, kusanganisira mishonga yekurapa uye zvinodhaka zvisiri pamutemo.

Mushonga wakagadzirirwa zvakananga mamiriro ekukurumidzira apo mumwe munhu atora opioid yakawandisa uye kufema kwavo kwakaderera kana kumira. Zviratidzo zvekuti mumwe munhu angangoda naloxone zvinosanganisira miromo yebhuruu kana zvipikiri, ruzha rwekugururuka, kurasikirwa nekuziva, uye kufema kunonoka kana kusipo.

Hezvino zviitiko zvakakosha apo naloxone nasal spray inogona kuponesa hupenyu:

• Kupfuura muyero kubva kumishonga yeopioid yakanyorerwa semuenzaniso oxycodone, morphine, kana fentanyl patches
• Heroin overdose
• Fentanyl poisoning kubva kumishonga yemumugwagwa
• Kumedzwa netsaona kweopioids nevana
• Kupfuura muyero kubva mukusanganisa opioids nedoro kana zvimwe zvinhu

Zvakakosha kunzwisisa kuti naloxone inoshanda kwenguva pfupi. Mushonga unowanzo gara maminitsi 30-90, nepo mamwe maopioids anogona kugara mumuviri kwenguva refu, zvichireva kuti mhedzisiro yekupfuura muyero inogona kudzoka.

Naloxone Nasal Spray Inoshanda Sei?

Naloxone nasal spray inoshanda nekukwikwidza neopioids kune zvakafanana zvinogamuchira muuropi hwako. Iyo ine simba rakasimba kune izvi zvinogamuchira kupfuura mazhinji maopioids, saka inogona kuvabvisa munzira uye kudzoreredza mhedzisiro yavo.

Kana maopioids akabatana nezvinogamuchira muuropi, anoderera kufema uye kurova kwemoyo kusvika pamatanho ane njodzi. Naloxone inovharira izvi zvinogamuchira zvakafanana, zvichibvumira kufema kwakajairika uye kuziva kuti kudzoka. Iyi nzira inoitika nekukurumidza, kazhinji mukati memaminitsi 2-5 ekutonga.

Mushonga unoonekwa seune simba zvine mwero mukuita kwayo. Iyo ine simba rakakwana rekudzosa kunyangwe maopioids ane simba sefentanyl, asi inogona kuda madosi akawanda eopioids akasimba kana enguva refu. Vamwe vanhu vangangoda dose yechipiri kana vasina kupindura kune yekutanga mukati memaminitsi 3-4.

Ndinofanira Kushandisa Sei Naloxone Nasal Spray?

Kushandisa naloxone nasal spray kwakananga, asi kuziva matanho akakodzera kunogona kuita musiyano pakati pehupenyu nerufu. Chekutanga, fonera 911 nekukasira usati kana mushure mekuisa mushonga.

Hezvino maitiro ekushandisa nemazvo:

1. Bvisa mudziyo we naloxone kubva mupaketi yawo
2. Bvisa chivharo chenjodzi cheyellow
3. Isa tipu yacho zvakasimba mumumhino mumwe kusvika zvigunwe zvako zvabata pasi pemhino dzemunhu
4. Dhinda plunger zvakasimba uye zvizere nechigunwe chako
5. Bvisa mudziyo wacho uye shandura munhu kuti arare padivi

Mushure me kupa mushonga, gara nemunhu wacho uye tarisa kufema kwavo. Kana vakasavuka mukati memaminitsi 2-3, vapa mushonga wechipiri mumumhino imwe kana uine mumwe uripo.

Haufaniri kunetseka nekupa naloxone kumunhu asina kutora maopioids. Mushonga hauzovakuvadzi, kunyangwe vanganzwa vasina kugadzikana kwenguva pfupi. Zviri nani nguva dzose kukanganisa nekuchenjerera mumamiriro ezvinhu ekukurumidzira.

Ndingashandisa Naloxone Nasal Spray kwenguva yakareba sei?

Naloxone nasal spray yakagadzirirwa mamiriro ekukurumidzira ekushandisa kamwe chete, kwete kurapwa kuri kuenderera mberi. Mudziyo wega wega une dose imwe, uye unofanirwa kuiisa nekukasira kana uchifungidzira kuti munhu akawandisa maopioids.

Mhedzisiro ye naloxone inowanzo gara maminitsi 30-90. Chiito ichi chenguva pfupi zvinoreva kuti kutarisirwa kwekurapa kwechimbichimbi kuchiri kwakakosha, kunyangwe munhu amuka. Iyo opioid iri pasi pemvura inogona kunge ichiripo muhurongwa hwavo uye inogona kukonzera imwe overdose kana naloxone yapera.

Kana mumwe munhu akawana overdoses dzakadzokororwa, vanoda kurapwa kwekurapa kwenyanzvi uye zvichida masevhisi ekutsigira addiction. Naloxone chishandiso chekununura chekukurumidzira, kwete mhinduro yenguva refu yekushandisa opioid disorder.

Ndezvipi Zvipingamupinyi zve Naloxone Nasal Spray?

Naloxone nasal spray inowanzo chengeteka, nemhedzisiro yakawanda iri nyoro uye yenguva pfupi. Mushonga wakagadzirirwa kuponesa hupenyu, saka mabhenefiti awo anopfuura njodzi dzinogona kuitika mumamiriro ezvinhu ekukurumidzira.

Mhedzisiro yakajairika yaungacherechedza inosanganisira:

• Mhuno inoyerera kana kushatirwa kwemhuno
• Kutemwa nemusoro
• Dizziness kana kunzwa kusimba
• Nausea kana dumbu kusagadzikana
• Kunzwa kusagadzikana kana kufara

Zvimwe zvinokonzera zvinotyisa hazviwanzoitika asi zvinogona kusanganisira zviratidzo zvekusiyana kamwe kamwe muvanhu vanoshandisa maopioids nguva dzose. Zviratidzo izvi zvinogona kusanganisira kushushikana kwakanyanya, kurwadziwa kwemhasuru, kurova kwemoyo nekukurumidza, kana chido chakasimba chemishonga.

Muzviitiko zvisingawanzoitiki, vanhu vanogona kusangana nekugadzirisa kwemuviri kune naloxone. Zviratidzo zvinosanganisira kuoma kufema, kuzvimba kwechiso kana huro, kana rash yeganda yakanyanya. Kana zviratidzo izvi zikaonekwa, tsvaga rubatsiro rwekurapa nekukurumidza.

Ndiani Asingafaniri Kushandisa Naloxone Nasal Spray?

Vanenge vese vanogona kushandisa naloxone nasal spray zvakachengeteka munguva yekukurumidzira, kusanganisira vakadzi vane pamuviri, vana, uye vanhu vakuru. Zvakanakira zvehupenyu zvemishonga zvinopfuura njodzi dzese.

Vanhu chete vanofanira kudzivisa naloxone ndevaya vane allergy yakanyanya kumishonga pachayo, izvo zvisingawanzoitiki. Kunyangwe vanhu vane dzimwe allergies kana mamiriro ekurapa vanogona kazhinji kushandisa naloxone zvakachengeteka panguva yekukurumidzira overdose.

Vanhu vanovimba nemuviri pane maopioids vachasangana nezviratidzo zvekusiya mushure mekuwana naloxone, asi izvi zvinotarisirwa uye zvenguva pfupi. Kusagadzikana kwekusiyana kwakachengeteka zvakanyanya pane imwe nzira yeoverdose isina kurapwa.

Mazita eNaloxone Brand

Naloxone nasal spray inowanikwa pasi pemazita akati wandei emhando, neNarcan ndiyo inonyanya kuzivikanwa. Narcan inowanikwa pamusoro-pe-counter mumakemisi mazhinji uye inowanzo kupihwa mahara kuburikidza nechirongwa chenharaunda.

Mamwe mazita emhando anosanganisira Kloxxado, iyo ine dose yepamusoro ye naloxone uye inogona kushanda zvakanyanya pamishonga ine simba sefentanyl. Zvese zvigadzirwa zvinoshanda nenzira imwechete asi zvinogona kunge zvine zvishoma zvakasiyana dosing recommendations.

Mishonga ye generic ye naloxone nasal spray inowanikwawo uye inoshanda zvakanyanya semhando dzemhando. Chinhu chakanyanya kukosha ndechokuva nekuwana chero chigadzirwa che naloxone pane kunetseka pamusoro pemhando dzakasiyana.

Zvimwe Zvinhu Zvokushandisa Panzvimbo pe Naloxone

Naloxone nasal spray ndiyo nzira iri nyore kushandisa yemushonga uyu, asi dzimwe sarudzo dziripo dzemamiriro akasiyana. Naloxone inojekisika inowanikwa kune nyanzvi dzezvekurapa uye dzimwe chirongwa zvemunharaunda, kunyange zvazvo ichida kudzidziswa kwakawanda kuti ishandiswe zvakachengeteka.

Zvishandiso zve auto-injector zvakaita seEvzio zvinopa mirairo inotungamirirwa nezwi yekupa naloxone kuburikidza neganda. Zvishandiso izvi zvinodhura asi zvinogona kubatsira vanhu vanonetseka kushandisa nasal spray.

Hakuna zvimwe zvinhu zvechokwadi zve naloxone zvekudzosa opioid overdoses. Zvimwe zvinodhaka zvakaita seflumazenil zvinoshanda kune dzimwe mhando dzeoverdoses, asi hazvizobatsiri ne opioid poisoning. Naloxone inoramba iri goridhe rekuita reversal ye opioid overdose.

Naloxone Nasal Spray Zviri Nani Pane Injectable Naloxone Here?

Naloxone nasal spray inopa zvakawanda zvakanakira pamusoro pemhando dzinojekisika, kunyanya kune vasiri vekurapa vashandisi. Iyo nasal spray haidi tsono, iyo inobvisa njodzi yekukuvara kwetsono uye inoita kuti isatyise kushandiswa nemitezo yemhuri kana shamwari.

Iyo absorption rate kuburikidza nemashwashwa emumhino inononoka zvishoma pane jekiseni, asi ichiri nekukurumidza zvakakwana kuti ive inoshanda zvakanyanya mumamiriro ezvinhu ekukurumidzira. Vanhu vazhinji vanopindura kune nasal naloxone mukati memaminitsi 2-5, zvichienzaniswa nemaminitsi 1-3 ejekiseni.

Injectable naloxone inogona kunge yakavimbika zvishoma mumamiriro akati wandei, senge kana mumwe munhu aine nasal congestion yakanyanya kana kukuvara. Zvisinei, nyore kushandisa uye kuchengeteka kwe nasal spray inoita kuti ive sarudzo inofarirwa yekugoverwa kwemunharaunda uye mabhokisi emhuri ekukurumidzira.

Mibvunzo Inowanzo Bvunzwa Pamusoro pe Naloxone Nasal Spray

Mubvunzo 1. Naloxone Nasal Spray Yakachengeteka Kuvakadzi Vane Pamuviri Here?

Hongu, spray yemumhino ye naloxone yakachengeteka kuvakadzi vane pamuviri vari kusangana ne opioid overdoses. Mushonga haupfuuri placenta zvakanyanya, uye kuponesa hupenyu hwamai ndicho chinhu chekutanga mune emergency ye overdose.

Vakadzi vane pamuviri vanovimba nemuviri pane maopioid vanogona kusangana nezviratidzo zve withdrawal mushure mekutambira naloxone, asi izvi zvakachengeteka zvakanyanya pane kubvumira overdose kuti ienderere mberi. Emergency medical care inofanira kutsvakwa nekukasira kune chero mukadzi ane pamuviri anotambira naloxone.

Q2. Ndingaita Sei Kana Ndikashandisa Naloxone Yakawandisa Netsaona?

Hazvigoneki kuti uoverdose pane spray yemumhino ye naloxone, kunyangwe ukashandisa madosi akawanda netsaona. Mushonga une safety margin yakakwirisa, uye naloxone yakawandisa haingakonzere mhedzisiro yekuwedzera kupfuura kuvhara opioid receptors.

Kushandisa naloxone yakawedzerwa kunogona kukonzera zviratidzo zve withdrawal zvakanyanya mune mumwe munhu anoshandisa maopioid nguva dzose, asi izvi hazvina njodzi. Munhu wacho anogona kunzwa asina kugadzikana, asi havazowana mhedzisiro inotyisa yehupenyu kubva ku naloxone yakawandisa.

Q3. Ndingaita Sei Kana Ndikakundikana Kupa Dose ye Naloxone?

Naloxone haisi mushonga waunotora pane schedule, saka haugone chaizvo "kukundikana" dose. Kana uchifungidzira kuti mumwe munhu anoda naloxone asi usati wapa, mupe nekukasira. Nguva yakakosha mumamiriro e overdose.

Kana wakapa dose imwe uye munhu wacho haasi kupindura mushure memaminitsi 2-3, pa dose yechipiri kana uine imwe iripo. Usamirira kana kuzeza kana hupenyu hwemumwe munhu huri mungozi.

Q4. Ndingamira Rini Kushandisa Naloxone?

Unomira kushandisa naloxone kana munhu wacho achifema zvakajairika uye achipindura, kana kana emergency medical services yasvika kuzotora kutarisirwa. Chishandiso chega chega che naloxone chinoshandiswa kamwe chete, saka haugone kuenderera mberi uchishandisa chimwe chete.

Yeuka kuti mhedzisiro ye naloxone ndeyenguva pfupi, inogara maminitsi 30-90. Munhu wacho anoda kuongororwa nachiremba kunyangwe akamuka, nekuti overdose inogona kudzoka kana naloxone yapera.

Q5. Ndingapa Naloxone kuvana here?

Hongu, naloxone nasal spray yakachengeteka kuvana vakamedza opioids netsaona. Vana vanogona kunge vachinyanya kunzwa kune opioids, saka vanowanzoita zvakanaka kurapwa ne naloxone.

Dosing yakafanana nevana nevakuru - imwe spray mumumhino mumwe. Fonera 911 nekukasira uye tevera matanho akafanana ekupa. Vana vanogamuchira naloxone vanoda kutarisirwa kwekurapa kwechimbichimbi kuti vave nechokwadi chekuti havazove nezviratidzo zve overdose zvinoenderera mberi.