Chii chinonzi Necitumumab: Zvazvinoshandiswa, Madosi, Migumisiro Yemuviri uye Zvimwe Zvakawanda

Necitumumab mushonga wekenza unotarwa uyo unobatsira kurapa rudzi rwakati rwakananga rwekenza yemumapapu inonzi squamous non-small cell lung cancer. Mushonga uyu unoshanda nekudzivisa mapuroteni anobatsira maseru ekenza kukura nekupararira mumuviri mako wese.

Kana chiremba wako akataura nezve necitumumab sechikamu chechirongwa chako chekurapa, unogona kunge uine mibvunzo yekuti inoshanda sei uye zvekutarisira. Ngatishande kuburikidza nezvose zvaunoda kuziva nezve mushonga uyu nenzira inoita seinodzoreka uye yakajeka.

Chii chinonzi Necitumumab?

Necitumumab imuviri wakagadzirwa murabhoritari unotarisa maseru ekenza zvakananga. Fungidzira sechidzitiro chinotungamirirwa chinotsvaga uye chinonamatira kumasero ekenza ichisiya maseru ako mazhinji ane hutano ega.

Mushonga uyu ndeweboka remishonga inonzi monoclonal antibodies. Aya mapuroteni akagadzirwa zvakakosha anogona kuziva uye kunamatira kune zvakanangwa pamasero ekenza. Kana yanamatira, necitumumab inobatsira kumisa kenza kubva pakukura uye inogona kubatsira immune system yako kurwisa chirwere ichi zvinobudirira.

Uchagamuchira necitumumab kuburikidza neIV infusion panzvimbo yekurapa kenza kana muchipatara. Mushonga uyu unouya semvura yakajeka inosanganiswa nemhinduro yesaline isati yapiwa kwauri kuburikidza nemuviri.

Chii chinonzi Necitumumab chinoshandiswa?

Necitumumab inobvumidzwa zvakananga kurapa squamous non-small cell lung cancer yakapararira kune dzimwe nhengo dzemuviri wako. Chiremba wako achanyora mushonga uyu chete kana kenza yako iine rudzi rwakati rwe squamous cell.

Iwe unowanzo gamuchira necitumumab yakasanganiswa nemishonga yekemotherapu inonzi gemcitabine uye cisplatin. Iyi nzira yekusanganisa inowanzo shanda zvirinani pane chemotherapy yoga nekuti mushonga wega wega unorwisa kenza nenzira dzakasiyana.

Chiremba wako wezve oncology achasimbisa kuti necitumumab yakakunakira iwe nemiedzo yakasiyana siyana. Izvi zvinogona kusanganisira sampuli yematishu kubva kancer yako uye scans kuti uone kuti chirwere chakatambanuka sei.

Necitumumab Inoshanda Sei?

Necitumumab inoshanda nekudzivisa protein inonzi EGFR (epidermal growth factor receptor) iyo inogara pamusoro pemaseru ekenza. Iyi protein inowanzoita kuti maseru akure uye aparadzane, asi maseru ekenza anowanzoita zvakawanda zvayo.

Kana necitumumab yakabatana neEGFR, zvakaita sekuisa kiyi pamusuwo uyo maseru ekenza anoshandisa kugamuchira zviratidzo zvekukura. Izvi zvinobatsira kuderedza kana kumisa kenza kubva pakukura nekupararira kunzvimbo itsva dzemuviri wako.

Mishonga iyi inoonekwa seyakasimba yekurapa kenza. Kunyangwe isina simba semamwe madhiragi echemotherapy, ichiri kuda kunyatso tarisa uye inogona kukonzera mhedzisiro yakakosha iyo timu yako yekurapa ichatarisa zvakanyanya.

Ndingatora Sei Necitumumab?

Uchagamuchira necitumumab kuburikidza neIV infusion inotora maminitsi makumi matanhatu. Chikwata chako chehutano chichakupai mushonga uyu panzvimbo yekurapa kenza kwavanogona kukutarisa zvakanyanya panguva uye mushure mekuiswa.

Usati wapiwa mushonga wega wega, ungangodaro uchagamuchira mishonga yekubatsira kudzivirira maitiro ekuita allergic. Izvi zvinogona kusanganisira antihistamines senge Benadryl kana steroids kuderedza mukana wekuita infusion.

Haufaniri kudzivisa chikafu usati wapiwa necitumumab, asi kugara uine mvura yakawanda nekunwa mvura yakawanda kunogona kubatsira muviri wako kugadzirisa mushonga uyu zvinobudirira. Mukoti wako achakupawo mvura yeIV panguva yekurapa.

Iyo infusion schedule inowanzo tevera pateni kwaunogamuchira necitumumab pamazuva 1 uye 8 eimwe neimwe yezuva rekurapa makumi maviri nerimwe. Chiremba wako achagadzirisa nguva iyi zvichienderana nekuti uri kupindura sei kurapwa uye kuti unonzwa sei.

Ndingatora Necitumumab Kwenguva Yakareba Sei?

Kureba kwemushonga we necitumumab kunosiyana zvakanyanya kubva kumunhu nemunhu. Vamwe vanhu vanoupiwa kwemwedzi yakati wandei, asi vamwe vanogona kuenderera mberi kwegore kana kupfuura kana uchishanda zvakanaka uye mhedzisiro yacho ichiri kutarisika.

Oncologist wako achatarisa nguva dzose kuti kenza yako iri kupindura sei kuburikidza nekutarisa uye bvunzo dzeropa. Kana kenza ikatanga kukura zvakare kana mhedzisiro yacho ikava yakaoma kutarisira, chiremba wako achakurukura kumisa necitumumab uye kutsvaga dzimwe nzira dzekurapa.

Sarudzo dzekurapa dzinoenderana nezvinhu zvakati wandei zvinosanganisira manzwiro ako, mhedzisiro yekutarisa kwako, uye hutano hwako hwese. Chikwata chako chekurapa chichava nekukurukurirana kwechokwadi newe nezvekupfuurira mberi kana kuchinja chirongwa chako chekurapa sezvo nguva ichienda mberi.

Ndezvipi Zvinhu Zvinokonzerwa neNecitumumab?

Semishonga yakawanda yekenza, necitumumab inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anoiziva nenzira imwechete. Kunzwisisa zvingaitika kunogona kukubatsira kuti unzwe wakagadzirira uye kuziva kuti ungataurirana riini nechikwata chako chehutano.

Mhedzisiro yakajairika yaungasangana nayo inosanganisira matambudziko eganda, maronda emuromo, uye shanduko mumazinga eropa ako ayo chiremba wako achatarisa kuburikidza nebvunzo dzenguva dzose dzelabhu.

Mhedzisiro Yakajairika

Mhedzisiro iyi inoitika muvanhu vakawanda vachitora necitumumab, asi kazhinji inogona kutarisika nekutarisirwa kwakakodzera uye kutarisisa:

• Kutsvukisa kweganda kana mabhampu akaita se acne, kunyanya pachiso chako nechipfuva
• Ganda rakaoma, rinokwenya iro rinogona kutsemuka kana kubvaruka
• Maronda emuromo kana kurwadziwa paunodya
• Dhiria kana zvigaro zvakasununguka
• Kuneta kana kunzwa wakaneta kupfuura zvakajairika
• Shanduko mumazinga ako emagnesium
• Matambudziko emuzvipikiri senge hutachiona kana kurwadziwa kutenderedza mibhedha yezvipikiri

Chikwata chako chehutano chine ruzivo rwekutarisira mhedzisiro iyi uye chinogona kupa mishonga kana mazano ekukubatsira kuti unzwe wakasununguka. Mazhinji ematambudziko aya anovandudzika nekufamba kwenguva kana kurapwa kwapera.

Mhedzisiro Yakakomba

Kunyange zvazvo zvisingawanzoitiki, dzimwe mhedzisiro dzinoda kutariswa kwechimbichimbi. Kuziva zviratidzo izvi zvekuyambira kunokubatsira kuti uwane rubatsiro nekukurumidza kana zvichidikanwa:

• Kusangana kweganda kwakanyanya nekupenya kana rash yakapararira
• Zviratidzo zveutachiona zvakaita sefivha, kutonhora, kana kuneta kusinganzwisisike
• Manyoka akanyanya asingavandudzike nemishonga
• Mavhiri eropa anokonzera kuzvimba kwemakumbo, kurwadziwa muchipfuva, kana kufema kwemhepo
• Matambudziko emoyo anosanganisira kurova kwemoyo kusingaenderane kana kurwadziwa muchipfuva
• Kusangana kwakanyanya kweallergy panguva yekupinza

Kana iwe ukasangana nezvipi zvazvo zvezviratidzo izvi, taura nechikwata chako cheoncology nekukurumidza kana kuenda kukamuri rekukurumidzira. Kuva nechirongwa chekusvika kuchikwata chako chekurapa mushure memaawa kunogona kupa rugare rwepfungwa.

Mhedzisiro Isingawanzoitiki asi Yakakosha

Dzimwe mhedzisiro dzinoitika kazhinji asi dzichiri kukodzera kutariswa. Chikwata chako chekurapa chichatarisa izvi kuburikidza nekutarisa nguva dzose uye bvunzo:

• Kudonha kwakanyanya muhuwandu hwemasero eropa ayo anowedzera njodzi yekutapukirwa
• Matambudziko eitsvo anogona kuchinja nzira yaunobuda nayo
• Kuzvimba kwemapapu kunokonzera kukosora kwenguva refu kana matambudziko ekufema
• Kusagadzikana kwakanyanya kweelectrolyte kunokanganisa rhythm yemoyo
• Matambudziko emaziso anosanganisira shanduko yekuona kana kurwadziwa

Kutarisa nguva dzose kunobatsira kubata nyaya idzi pakutanga kana dziri nyore kubata. Chikwata chako chehutano chichagadzirisa chirongwa chako chekurapa kana chero shanduko dzinonetsa dzikaitika.

Ndiani Asingafaniri Kutora Necitumumab?

Necitumumab haina kukodzera munhu wese ane gomarara remapapu. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa uye mamiriro ako ehutano azvino usati watsanangura mushonga uyu.

Vanhu vane marudzi asiri e-squamous egomarara remapapu havafaniri kugamuchira necitumumab nekuti zvidzidzo zvinoratidza kuti hazvibatsiri uye zvinogona kukonzera kukuvadzwa kukuru pane kubatsirwa muzviitiko izvi. Chiremba wako achayedza tishu yako yegomarara kuti asimbise rudzi rwe squamous usati watanga kurapwa.

Kana uine matambudziko akakomba emoyo, chirwere cheitsvo, kana mamwe mamiriro ezvinhu ekurapa, chiremba wako anogona kusarudza dzimwe nzira dzekurapa. Vachafungawo chero mishonga yaunotora parizvino kudzivirira kusangana kunotyisa.

Kuzvitakura nekuyamwisa zvinhu zvakakosha kufunga nezvazvo. Necitumumab inogona kukuvadza vana vari kukura, saka uchada kushandisa nzira yekudzivirira kubata pamuviri inoshanda panguva yekurapa uye kwemwedzi yakati wandei mushure meizvozvo kana iwe uchikwanisa kubata pamuviri.

Zita reBrand reNecitumumab

Necitumumab inotengeswa pasi pezita rebrand Portrazza. Unogona kuona zita rimwe chete pamarekodhi ako ekurapa, mapepa einishuwarenzi, kana mavara emishonga.

Kunyangwe chiremba wako achitaura nezvayo se necitumumab kana Portrazza, vari kutaura nezve mushonga mumwe chete. Mazita ese ari maviri anooneka pamarondedzero epamutemo uye zvirongwa zvekurapa.

Zvimwe Zvinhu zveNecitumumab

Kana necitumumab isiri yako kana ikamira kushanda nemazvo, dzimwe nzira dzekurapa dziripo dzekenza yemapapu isiri diki yesquamous cell. Oncologist wako achakurukura izvi zvimwe zvinhu zvichibva pamamiriro ako chaiwo.

Mamwe marapirwo akatarwa se pembrolizumab (Keytruda) kana nivolumab (Opdivo) anoshanda zvakasiyana nekubatsira immune system yako kurwisa kenza. Aya ma immunotherapy drugs akaratidza vimbiso mukurapa kenza yemapapu, kunyangwe achishanda zvakanaka mumamiriro akasiyana.

Mibatanidzwa yechinyakare ye chemotherapy inoramba iri nzira dzakakosha dzekurapa. Chiremba wako angakurudzira carboplatin uye paclitaxel kana mamwe mibatanidzwa zvichienderana nehutano hwako hwese uye kurapwa kwakapfuura.

Miedzo yekiriniki inopa mukana wekurapa kutsva kwejekerere kunogona kuve marapirwo akajairika mune ramangwana. Oncologist wako anogona kukubatsira kuongorora kana chero miedzo iripo ingave yakakodzera mamiriro ako.

Necitumumab iri nani pane Cetuximab here?

Necitumumab na cetuximab zvose ma antibodies anovavarira EGFR, asi anoshandiswa kumhando dzakasiyana dzekenza. Cetuximab inonyanya kushandiswa kune colorectal uye musoro nemutsipa cancer, nepo necitumumab ichibvumirwa zvakananga kune squamous lung cancer.

Kufananidza zvakananga pakati pemishonga iyi kwakaoma nekuti inorapa mhando dzakasiyana dzekenza. Imwe neimwe yakadzidzwa zvakanyanya mumhando dzayo dzekenza dzakabvumirwa uye yakaratidza mabhenefiti anokosha kana ichishandiswa zvakakodzera.

Oncologist wako achasarudza mushonga wakakodzera kune yako chaiyo mhando yekenza uye mamiriro ako. Sarudzo haina chekuita nekuti ndiripi mushonga uri

Kana ukaona zviratidzo zvakadai sekuoma kufema, kusungirirwa pachipfuva, mburwa yakanyanya, kana dzungu panguva yekupinza mushonga wako, udza mukoti wako nekukasira. Vakadzidziswa kuziva nekukurumidza nekurapa maitiro ekupinza mushonga.

Chikwata chako chekurapa chinogona kuderedza kana kumisa kupinza mushonga kwenguva pfupi uye kukupa mishonga yekubatsira nekuita. Mazhinji maitiro ekupinza mushonga anogoneka, uye vanhu vazhinji vanogona kuramba vachirapwa nekuchenjerera kwakakodzera.

Q4. Ndingamira rini kutora necitumumab?

Sarudzo yekumira necitumumab inoenderana nekuti iri kushanda sei uye kuti uri kutsungirira sei kurapwa. Oncologist wako achagara achiongorora mhinduro yako kuburikidza nekutarisa uye bvunzo dzeropa kuti aite izvi.

Unogona kumira necitumumab kana kenza yako ichienderera mberi pasinei nekurapwa, kana mhedzisiro yacho ikava yakaoma zvikuru kudzora, kana ukawana mhinduro yakanaka uye chiremba wako anokurudzira kuzorora kurapwa. Sarudzo idzi dzinogara dzichiitwa pamwe chete pakati pako nechikwata chako chehutano.

Q5. Ndingatora mimwe mishonga ndichiri kutora necitumumab here?

Mishonga yakawanda inogona kutorwa zvakachengeteka ne necitumumab, asi mimwe inogona kukanganisa kana kuwedzera mhedzisiro. Nguva dzose udza oncologist wako nezvemishonga yese, zvinowedzera, uye mavitamini auri kutora.

Chikwata chako chehutano chichaongorora runyorwa rwemishonga yako usati watanga necitumumab uye chinogona kugadzirisa zviyero kana nguva yemimwe mishonga. Chengeta runyorwa rwakagadziridzwa rwemishonga yako yese uye uuye nayo kumusangano wega wega.