Chii chinonzi Nesiritide: Zvinoshandiswa, Madosi, Migumisiro Yemativi uye Zvimwe

Nesiritide imhando yekugadzirwa yehomoni yechisikigo inogadzirwa nemoyo wako inonzi B-type natriuretic peptide (BNP). Mushonga uyu unobatsira moyo wako kupomba zvakanyanya uye unoderedza kushushikana pamoyo wako kana uri kusangana nekukundikana kwemoyo kwakanyanya.

Chiremba wako angakurudzira nesiritide kana moyo wako uchida rubatsiro rwekukurumidza panguva yekuvharirwa muchipatara. Yakagadzirirwa kubatsira muviri wako kudzora kuunganidzwa kwemvura uye kuvandudza kuyerera kweropa kana dzimwe nzira dzekurapa dzisingape zororo rakakwana.

Nesiritide Inoshandiswa Kunei?

Nesiritide inorapa acute decompensated heart failure, zvinoreva kuti moyo wako unongoerekana wava kutadza kupomba ropa nemazvo. Izvi zvinowanzoitika kana kukundikana kwemoyo kusingaperi kuchikura nekukurumidza, kazhinji kuchida kutarisirwa muchipatara nekukurumidza.

Panguva yekukundikana kwemoyo, muviri wako unochengeta mvura yakawandisa, zvichiita kuti moyo wako ushande zvakanaka. Nesiritide inobatsira nekuzorodza tsinga dzeropa uye kukurudzira itsvo dzako kubvisa mvura yakawandisa kuburikidza nekuyerera. Chiito ichi kaviri chinoderedza basa pamoyo wako uri kutambura.

Chikwata chako chekurapa chichashandisa mushonga uyu muzvipatara chete uko vanogona kunyatso tarisa kushanda kwemoyo wako uye kudzvinyirirwa kweropa. Haisi chinhu chaungatora kumba, sezvo ichida kutarisirwa kwekurapa kwakanyatsoitwa panguva yekurapa.

Nesiritide Inoshanda Sei?

Nesiritide inoshanda nekutevedzera hormone inogadzirwa nemoyo wako pachisikigo kana uri pasi pekushushikana. Kana moyo wako uchitambura, unoburitsa BNP kuti ubatsire kuzvidzivirira, asi dzimwe nguva haigadziri zvakakwana panguva yezviitiko zvakanyanya.

Mishonga iyi inoshanda pane zvimwe zvinogamuchira muropa rako, zvichikonzera kuti zvizorore uye zviwedzere. Izvi zvinoita kuti mwoyo wako uwedzere kubuda ropa mumuviri wako wese. Panguva imwecheteyo, inotumira chiratidzo kumatsvo ako kuti abvise munyu wakawandisa nemvura, zvichideredza mvura yakawandisa iri kutambudza mwoyo wako.

Funga nezvazvo sekupa mwoyo wako rubatsiro panguva dzayo dzakaoma. Mishonga iyi inoonekwa seyepakati nepakati uye inoshanda nekukurumidza, ndosaka nyanzvi dzezvekurapa dzichii shandisa mumamiriro ezvinhu akakomba pane manejimendi emwoyo enguva refu.

Ndingatora sei Nesiritide?

Hauzotori nesiritide iwe pachako nekuti inongopiwa kuburikidza nemutsara weintravenous (IV) muchipatara. Chikwata chako chehutano chichaisa chubhu diki mutsinga, kazhinji muruoko rwako, uye chitumire mishonga yacho zvakananga muropa rako.

Kurapa kunowanzo kutanga nedosi diki yekutanga inoteverwa nekupinza kunoenderera mberi kunogona kutora maawa makumi maviri nemana kusvika makumi mana nemasere kana kupfuura, zvichienderana nekuti mwoyo wako unopindura sei. Chikwata chako chekurapa chichachinja dose zvichienderana neropa rako, kumhanya kwemoyo, uye kuti itsvo dzako dzinoshanda sei.

Haufanire kunetseka nezve nguva yekudya kana kutora mamwe mishonga ne nesiritide sezvo ichipfuura zvachose mudumbu rako. Zvisinei, vanopa hutano vako vachazvibatana zvakanyatsoenderana nemamwe mishonga yemoyo yaunogamuchira kuti vave nechokwadi chekuti zvese zvinoshanda pamwechete zvakachengeteka.

Ndingatora Nesiritide kwenguva yakareba sei?

Vanhu vazhinji vanogamuchira nesiritide kwenguva pfupi, kazhinji maawa makumi maviri nemana kusvika makumi mana nemasere panguva yekugara kwavo muchipatara. Nguva chaiyo inoenderana nekuti zviratidzo zvako zvekukundikana kwemoyo zvinovandudzika sei nekukurumidza uye kuti muviri wako unopindura sei kurapwa.

Chikwata chako chekurapa chichagara chichiongorora mamiriro ako uye zvishoma nezvishoma kuderedza mushonga sezvo basa remoyo wako richigadzikana. Vachatarisa zviratidzo zvekuti mazinga emvura yako ari kuvandudzika, kufema kwako kuri nyore, uye moyo wako uri kupomba zvakanyanya zvinobudirira vasati vamisa kuisa mushonga.

Paunenge wagadzikana, vanachiremba vako vanogona kukuchinjisa kumishonga yemoyo inotorwa nemuromo yaunogona kutora kumba. Nesiritide yakagadzirirwa zvakananga sekurapa kwenguva pfupi yekukubatsira kuburikidza nedambudziko rakaoma, kwete sechirongwa chekurapa kwenguva refu.

Ndezvipi Zvakaipa zveNesiritide?

Mhedzisiro yakajairika yaungasangana nayo ndiyo kudzikira kweropa, izvo zvinogona kukonzera kuti unzwe dzungu kana musoro. Izvi zvinoitika nekuti mushonga unozorodza midzi yeropa rako, uye dzimwe nguva kumanikidzwa kweropa rako kunogona kudonha kupfuura zvaitarisirwa.

Heano mhedzisiro iyo chikwata chako chekurapa chichatarisa zvakanyatsonaka panguva yekurapa kwako:

• Kudzikira kweropa (hypotension) - kunogona kukonzera dzungu kana kunzwa kufenda
• Musoro - kazhinji nyoro kusvika pakati
• Nausea - inogona kuuya nekufamba panguva yekurapa
• Kurwadziwa kwemumashure - kazhinji kwenguva pfupi
• Dzungu - kunyanya kana uchichinja nzvimbo
• Kuzvidya mwoyo kana kusagadzikana - kunogona kuitika sezvo muviri wako uchigadzirisa

Chikwata chako chehutano chinotarisa izvi zvinokonzeresa zvakanyanya uye chinogona kugadzirisa chiyero chako kana zvichidikanwa. Mazhinji emhedzisiro anogoneka uye anovandudzika sezvo basa remoyo wako richigadzikana.

Kazhinji, vamwe vanhu vanogona kusangana nemhedzisiro yakakomba inoda kutariswa nekukurumidza:

• Kudonha kwakanyanya kweropa kunoda kugadziriswa kwemushonga
• Kurova kwemoyo kusina kujairika kana shanduko yerhythm yemoyo
• Shanduko yebasa reitsvo - inotariswa kuburikidza nemiedzo yeropa
• Allergic reactions - isingawanzoitiki asi inogoneka nemushonga chero upi zvake

Nzvimbo yechipatara inovimbisa kuti chero zviratidzo zvinonetesa zvabatwa uye kugadziriswa nekukurumidza, zvichikupa ruzivo rwekurapa rwakachengeteka.

Ndiani Asingafaniri Kutora Nesiritide?

Nesiritide haina kukodzera munhu wese ane matambudziko emoyo. Vanachiremba vako vachaongorora nhoroondo yako yekurapa uye mamiriro ako azvino vasati vasarudza kana kurapwa uku kwakakukodzera.

Haufanire kugamuchira nesiritide kana uine mamwe mamiriro emoyo anogona kuita kuti kurapwa kuve kwengozi:

• Cardiogenic shock - kana moyo wako usingakwanise kupomba ropa rakakwana kumitezo inokosha
• Kuderera kwakanyanya kweropa risingapinduri kune dzimwe nzira dzekurapa
• Mamiriro emoyo anodzivirira kana anovharidzira anokanganisa kuyerera kweropa
• Kuzivikanwa kweallergies kune nesiritide kana mishonga yakafanana

Chikwata chako chekurapa chichashandisawo chenjedzo yakawedzerwa kana uine matambudziko eitsvo, sezvo mushonga unokanganisa maitiro eitsvo dzako kugadzirisa mvura. Vachatarisa basa reitsvo dzako zvakanyanya panguva yekurapa kuti vave nechokwadi chekuti inoramba yakachengeteka kwauri.

Kuzvitakura nekuyamwisa zvinoda kufunga kwakakosha, kunyangwe kukundikana kwemoyo panguva yekuzvitakura kuri mamiriro akakomba anogona kuda kurapwa uku pasinei nekusazivikanwa. Vanachiremba vako vachayerera njodzi nemabhenefiti zvakanyatsonaka kana wakazvitakura kana kuyamwisa.

Mazita eNesiritide Brand

Nesiritide inonyanya kuzivikanwa nezita rayo rekuti Natrecor muUnited States. Iyi ndiyo vhezheni yaungangosangana nayo muzvipatara, sezvo iri iyo fomu yekutanga inowanikwa yekushandiswa kwekiriniki.

Mishonga inogona kutaurwa nezita rayo re generic (nesiritide) kana zita remhando (Natrecor) mumarekodhi ako ekurapa uye mapepa ekubuda. Mazita ese ari maviri anoreva mushonga mumwe chete, saka usavhiringidzika kana ukaona mazwi akasiyana achishandiswa nenhengo dzakasiyana dzechikwata chako chehutano.

Kusiyana nemishonga yakawanda ine mhando dzakawanda dzemhando, nesiritide ine shanduko shoma dzemhando nekuti mushonga wechipatara wakakosha panzvimbo yemushonga unowanzo nyorerwa varwere vanobuda.

Zvimwe Zvinhu Zviri Panzvimbo yeNesiritide

Mishonga yakati wandei inogona kurapa kutadza kwemoyo kwakanyanya, kunyangwe imwe neimwe ichishanda zvakasiyana uye inogona kunge yakakodzera zvichienderana nemamiriro ako chaiwo. Vanachiremba vako vanosarudza zvichienderana nekushanda kwemoyo wako, kudzvanywa kweropa, uye hutano hwematsvo.

Heano mamwe maitiro makuru ayo timu yako yekurapa ingafunga nezvayo:

• Dobutamine - inosimbisa kuita kwemoyo asi inogona kuwedzera kumhanya kwemoyo
• Milrinone - inovandudza kupomba kwemoyo uye inozorodza tsinga dzeropa
• Furosemide (Lasix) - inobvisa mvura yakawandisa kuburikidza nekuwedzera weti
• Nitroglycerin - inozorodza tsinga dzeropa kuderedza basa remoyo
• Dopamine - inotsigira kudzvanywa kweropa uye kushanda kwemoyo

Imwe neimwe yemishonga iyi ine simba rakasiyana uye zvinhu zvekufunga nezvazvo. Vamwe vanoshanda zviri nani kune vanhu vane kudzvanywa kweropa kwakaderera, nepo vamwe vachisarudzwa kana kushanda kwematsvo kuri kunetsa. Chikwata chako chehutano chichasarudza sarudzo inoenderana nezvido zvako zvemunhu uye mamiriro ekurapa.

Ko Nesiritide Ari Nani Kupfuura Dobutamine Here?

Nesiritide na dobutamine vanoshanda zvakasiyana kubatsira moyo wako, saka "zviri nani" zvinoenderana nemamiriro ako chaiwo ekurapa. Nesiritide inotarisa pakuzorodza tsinga dzeropa uye kubvisa mvura, nepo dobutamine ichisimbisa zvakananga chiito chekupomba chemoyo wako.

Vanachiremba vako vangasarudza nesiritide kana uine kudzvanywa kweropa kwakanyanya pamwe nekutadza kwemoyo, sezvo ichibatsira kuderedza kudzvanywa kweropa uchitsigira kushanda kwemoyo. Dobutamine inogona kusarudzwa kana moyo wako uchida kukurudzirwa kwakananga kuti upombe zvinobudirira, kunyanya kana kudzvanywa kweropa rako kwakatoderera.

Vamwe vanhu vanobatsirwa nekugamuchira mishonga miviri pamwechete, sezvo ichitsinhirana mhedzisiro yavo. Chikwata chako chekurapa chichafunga nezve ropa rako, rhythm yemoyo, basa reitsvo, uye mamiriro ako ese paachisarudza nzira inoshanda zvakanyanya pakupora kwako.

Mibvunzo Inowanzo Bvunzwa Nezve Nesiritide

Nesiritide Yakachengeteka Kune Vanhu Vane Chirwere Cheitsvo Here?

Nesiritide inoda kunyatso tariswa muvanhu vane matambudziko eitsvo, asi inogona kushandiswa zvakachengeteka muzviitiko zvakawanda. Mushonga unokanganisa maitiro anoita itsvo dzako mvura nemunyu, izvo chaizvo chikamu chekuti inobatsira sei kukundikana kwemoyo wako.

Chikwata chako chekurapa chichaongorora basa reitsvo dzako nemiedzo yeropa usati watanga kurapwa uye ucharamba uchitarisa panguva yako yese yekugara. Vanogona kugadzirisa muyero kana kusarudza mushonga wakasiyana kana itsvo dzako dzisingashande zvakanaka kuti dzibate shanduko dzinokonzerwa ne nesiritide.

Muzviitiko zvimwe, kukundikana kwemoyo pachako kuri kuisa kushushikana paitsvo dzako, uye kurapa kukundikana kwemoyo ne nesiritide kunogona kubatsira kuchengetedza basa reitsvo dzako munguva refu.

Ndingaita Sei Kana Ndichiwana Zvinetso Zvenguva Yekurapa?

Sezvo uchave muchipatara uchigamuchira nesiritide, unofanira kukurumidza kuudza mukoti wako kana chiremba nezve chero zviratidzo zvisinganzwisisike zvaunosangana nazvo. Usamirira kana kufunga kuti zviratidzo zvichaenda zvega.

Chikwata chako chehutano chinotarisira kukutarisa zvakanyanya panguva yekurapa uye chinoda kuziva nezve chero shanduko mukuona kwako. Vanogona kukurumidza kugadzirisa muyero wemishonga yako, kukupa mamwe marapirwo ekugadzirisa matambudziko, kana kuchinjira kumushonga wakasiyana kana zvichidikanwa.

Zviratidzo zvakajairika zvakaita sedzungu diki kana kurwadziwa nemusoro zvinowanzoitika nekupindira kuri nyore, nepo zviratidzo zvakakomba zvinogona kuda shanduko yemishonga nekukurumidza kuti ikuchengetedze.

Ndingatora Mishonga Yangu Yemoyo Yenguva Dzose Ndichigamuchira Nesiritide Here?

Vanachiremba venyu vachaongorora mishonga yenyu yese yenguva dzose uye vachasarudza kuti ndedzipi dzekuenderera mberi, kumisa, kana kugadzirisa iwe paunenge uchigamuchira nesiritide. Mimwe mishonga yemoyo inoshanda zvakanaka pamwe chete ne nesiritide, nepo imwe ingada shanduko yenguva pfupi.

Mishonga yekudzikisa ropa inowanzoitisa kugadziriswa sezvo nesiritide inogona kudzikisa ropa. Chikwata chako chekurapa chichatarisa ropa rako zvakanyanya uye chichachinja mimwe mishonga sezvinodiwa kuti uchengetedze mazinga akachengeteka.

Usambomira kana kutanga chero mishonga wega paunenge uchigamuchira nesiritide. Nguva dzose kurukura chero zvinokunetsa pamusoro pemishonga yako nechikwata chako chehutano, sezvo vachifanira kuronga zvese zvakanyatsonaka kuchengetedzeka kwako.

Ndingadzokera Rini Kumba Mushure meNesiritide Kurapa?

Vanhu vazhinji vanogona kuenda kumba maawa makumi maviri nemana kusvika makumi mana nemasere mushure mekurapa kwavo nesiritide kwapera, asi izvi zvinoenderana nekuti kutadza kwemoyo wako kwakavandudzika sei uye kana iwe wakagadzikana pamushonga wako mutsva.

Vanachiremba vako vachada kuona kuti mazinga ako emvura akavandudzika, kufema kwako kuri nyore, uye basa remoyo wako rakagadzikana usati waburitswa. Vachaitawo shuwa kuti unonzwa wakasununguka nemishonga mitsva yaunenge uchitora kumba.

Kuchinja kubva kuchipatara kuenda kumba kunosanganisira kuronga kwakanyatsonaka kuti uve nechokwadi chekuti kutadza kwemoyo wako kunoramba kuchidzora. Chikwata chako chekurapa chichaita nguva dzekutevera uye chichapa mirairo yakajeka yekugadzirisa mamiriro ako kumba.

Ndingazoda Nesiritide Zvakare Munguva Yemberi?

Kana iwe uchizoda nesiritide zvakare zvinoenderana nekuti kutadza kwemoyo wako kunodzorwa sei nemishonga yako iripo uye manejimendi ehupenyu. Vamwe vanhu vane chiitiko chimwe chete chinoda nesiritide uye vanobva vaita zvakanaka nemishonga yemuromo kwenguva refu.

Vamwe vane chirwere chemoyo chakanyanya vangada kupinda muchipatara nguva nenguva uye vangagamuchira nesiritide zvakare munguva dzeramangwana. Chiremba wemoyo wako achashanda newe kuti uvandudze chirongwa chako chekurapa kwenguva refu kuti uderedze mukana wekuda kurapwa muchipatara.

Chinangwa nguva dzose ndechekuchengeta chirwere chemoyo chako chichidzoreka zvakanaka kumba nemishonga yaunogona kutora nemuromo, kuongorora nguva dzose, uye kugadzirisa mararamiro anotsigira hutano hwemoyo wako.