Chii chinonzi Olanzapine-uye-Samidorphan: Zvinoshandiswa, Dosage, Side Effects uye Zvimwe

Olanzapine-uye-samidorphan mushonga unosanganisa unovandudza schizophrenia uye bipolar disorder apo uchideredza kumwe kuwedzera uremu kunowanzoenderana ne olanzapine yega. Iyi pairing inovandudza inosanganisa mabhenefiti akaratidzwa ehutano hwepfungwa hwe olanzapine pamwe chete ne samidorphan, iyo inobatsira kurwisa tsika ye olanzapine yekukonzera kuwedzera kukuru kwehuremu.

Unogona kuziva mushonga uyu nezita rayo remhando Lybalvi, iro rakagadzirirwa zvakananga kugadzirisa imwe yeiyo inonyanya kunetsa mhedzisiro yekurapa kwechinyakare antipsychotic. Iyo musanganiswa inopa tariro kune vanhu vanoda mushonga wepfungwa unovandudza asi vanoda kuderedza shanduko dzisingadiwe dzehuremu.

Chii chinonzi Olanzapine-uye-Samidorphan?

Olanzapine-uye-samidorphan mushonga wemishonga unosanganisa zvinoshanda zviviri mupiritsi rimwe. Olanzapine ndeyeboka remishonga inonzi atypical antipsychotics, nepo samidorphan iri opioid receptor antagonist iyo inobatsira kuderedza kuwedzera uremu.

Iyo musanganiswa inoshanda nekubvumira olanzapine kuita basa rayo rekugadzirisa chemistry yehuropi apo samidorphan inodzivisa mamwe ma receptors anobatsira kuwedzera chido uye kuwedzera uremu. Iyi pairing inomiririra kufambira mberi kukuru mumishonga yepfungwa, ichigadzirisa zvese zviratidzo zveutano hwepfungwa uye kunetseka kwemhando yehupenyu.

Chiremba wako angangofunga nezvemusanganiswa uyu kana iwe wakawana mhedzisiro yakanaka ne olanzapine asi wakatambura nekuwedzera uremu, kana kana uri kutanga kurapwa uye uchida kuderedza iyi mhedzisiro kubva pakutanga.

Chii chinonzi Olanzapine-uye-Samidorphan chinoshandiswa?

Iyi musanganiswa wemishonga unovandudza mamiriro maviri makuru ehutano hwepfungwa: schizophrenia uye bipolar I disorder. Ye schizophrenia, inobatsira kubata zviratidzo zvakaita se hallucinations, delusions, uye kufunga kusina kurongeka izvo zvinogona kukanganisa hupenyu hwako hwezuva nezuva.

Mu chirwere che bipolar I, mushonga unobatsira kugadzirisa zvikamu zvemafungiro, kunyanya zvikamu zvemanic kana zvakasanganiswa zvinogona kusanganisira mafungiro akakwira, simba rakawedzera, uye kutadza kutonga. Inogona kushandiswa yega kana pamwe chete nemamwe magadziriso emood, zvichienderana nezvido zvako.

Mupi wako wehutano achasarudza kana musanganiswa uyu wakakukodzera zvichienderana nekuongororwa kwako, mhinduro dzakapfuura dzekurapa, uye zvinhu zvehutano hwemunhu. Chinangwa ndechokugara uchitsvaga kurapwa kunoshanda zvakanyanya nemigumisiro mishoma inonetsa.

Olanzapine-uye-Samidorphan Inoshanda Sei?

Musanganiswa uyu unoshanda kuburikidza nemaitiro maviri akasiyana muuropi hwako nemuviri. Olanzapine inovhara mamwe ma neurotransmitter receptors, kunyanya dopamine uye serotonin receptors, izvo zvinobatsira kugadzirisa kusagadzikana kwemakemikari kunobatanidzwa nemamiriro epfungwa.

Panguva imwecheteyo, samidorphan inovhara opioid receptors iyo olanzapine inogona kumisa, iyo inowanzoita kuti muwedzere chido uye kuwedzera uremu. Funga nezva samidorphan sechivharo chinodzivirira chinodzivirira zvimwe zvezvinhu zvisingadiwi zve olanzapine uku ichibvumira mabhenefiti ayo ekurapa kuti aenderere mberi.

Mushonga uyu unoonekwa seune simba zvine mwero muchikamu che antipsychotic. Inoshanda mukugadzirisa zviratidzo zvakakomba zveutano hwepfungwa uku ichipa manejimendi ari nani uremu pane olanzapine yega, kunyangwe ichiri kuda kunyatsoongororwa uye kutevera nguva dzose nemupi wako wehutano.

Ndingatora Sei Olanzapine-uye-Samidorphan?

Tora mushonga uyu sezvakanyorwa nachiremba wako, kazhinji kamwe chete pazuva uine kana pasina chikafu. Unogona kuitora nemvura, mukaka, kana muto - chero zvinoita sekunyaradza kwauri.

Hapana chinodiwa chaicho chekudya usati kana mushure mekutora mushonga, kunyangwe kuitora nechikafu kungabatsira kuderedza chero dumbu rinogumbura. Vamwe vanhu vanozviwana zvichibatsira kuitora panguva imwe chete zuva rega rega kuti vachengetedze mazinga akagadzikana muhurongwa hwavo.

Kana uri kuchinja kubva ku olanzapine yakajairika kuenda kumubatanidzwa uyu, chiremba wako achakutungamira mukuchinja zvakanyatsonaka. Usambofa wakarega kutora mushonga uyu kamwe kamwe, sezvo izvi zvinogona kukonzera zviratidzo zvekubviswa kana kudzoka kwezviratidzo zvako zvepfungwa.

Medza piritsi rose risina kupwanya, kutsenga, kana kuputsa. Mushonga wakagadzirirwa kuburitsa zvakanaka kana watorwa usina kukuvadzwa, saka kuchinja piritsi kunogona kukanganisa kuti rinoshanda sei.

Ndingatora Olanzapine-uye-Samidorphan Kwenguva Yakareba Sei?

Kureba kwekurapa kunosiyana zvakanyanya kubva kumunhu nemunhu uye kunoenderana nemamiriro ako chaiwo uye mhinduro kumushonga. Vanhu vazhinji vane schizophrenia kana bipolar disorder vanoda kurapwa kwenguva refu kuti vachengetedze kugadzikana uye kudzivirira kudzokera kwezviratidzo.

Chiremba wako achagara achiongorora kuti mushonga uri kushanda sei kwauri uye kana uri kusangana nemamwe mativi anokanganisa. Aya maonero anobatsira kuona kana uchifanira kuenderera mberi, kugadzirisa muyero, kana kufunga nezvimwe zvingasarudzwa zvekutarisirwa.

Kune vamwe vanhu, kurapwa kunogona kuenderera mberi kwemwedzi kana makore, nepo vamwe vangada kugadzirisa nekukurumidza. Chinhu chakakosha ndechichengetedza kutaurirana kwakavhurika nechiremba wako nezvekuti uri kunzwa sei mupfungwa nemuviri.

Usambofa wakasarudza kumisa mushonga uyu wega, kunyangwe uri kunzwa zviri nani. Kumisa kamwe kamwe kunogona kukonzera zviratidzo zvakakomba zvekubviswa uye kudzoka kwezviratidzo zvepfungwa zvinogona kuoma kurapa.

Ndezvipi Zvakaipa zveOlanzapine-uye-Samidorphan?

Semishonga yese, olanzapine-uye-samidorphan inogona kukonzera mativi, kunyangwe kwete munhu wese anozviwana. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakagadzirira uye uzive kuti ungataurirana riini nechiremba wako.

Zvimwe zvinokonzera zvinowanzoitika zvaungatarisira zvinosanganisira kurara, dzungu, uye muromo wakaoma. Izvi zvinowanzoita zviri nani muviri wako paunojaira mushonga, kazhinji mukati memavhiki mashoma ekutanga ekurapa.

Zvimwe Zvinokonzera Zvakajairika

Heano zvimwe zvinokonzera zvinowanzoitika, zvichikanganisa vanhu vazhinji vanotora mushonga uyu:

• Kurara kana kunyaradzwa, kunyanya kana uchitanga
• Dzungu kana musoro unorema, kunyanya kana uchimira
• Muromo wakaoma unogona kuvandudzwa nenguva
• Kuvharika kwemudumbu kunogona kutarisirwa nekuchinja kudya
• Kuwedzera chido chekudya, kunyangwe kazhinji kushoma pane olanzapine yega
• Kuneta kana kunzwa kuneta kupfuura zvakajairika
• Musoro unowanzoenda sezvo muviri wako uchijaira

Izvi zvinokonzera zvinowanzoitika uye zvinowanzoita zvishoma sezvo muviri wako uchijaira mushonga. Mupi wako wehutano anogona kupa nzira dzekubatsira kuderedza kukanganisa kwavo muhupenyu hwako hwezuva nezuva.

Zvimwe Zvisingawanzoitiki asi Zvakakomba Zvinokonzera

Nepo zvisingawanzoitiki, zvimwe zvinokonzera zvinoda kutariswa kwekurapa nekukasira nekuti zvinogona kuva zvakanyanya:

• Kuwedzera uremu zvakanyanya pasinei nekudzivirira kwe samidorphan
• Mazinga epamusoro eshuga yeropa kana zviratidzo zvechirwere cheshuga
• Kufamba kwemhasuru kusinganzwisisike kana kuoma
• Allergic reactions yakakomba ine rash, kuzvimba, kana kuoma kufema
• Kuchinja kwemoyo rhythm kana kurwadziwa muchipfuva
• Dzungu rakanyanya kana kufenda
• Zviratidzo zvehutachiona senge fivha kana kurwadziwa kwehuro

Kana iwe ukawana chero chimwe chezviratidzo izvi, taura nemupi wako wehutano nekukasira. Kuzivikanwa nekukurumidza uye kurapwa kwezvinokonzera zvakakomba zvinogona kudzivirira matambudziko uye kuona kuchengeteka kwako.

Zvisingawanzoitiki asi Zvakakomba Zvinokonzera

Izvi zvinokonzera hazviwanzoitiki asi zvinoda kutariswa kwekurapa nekukasira kana zvikaitika:

• Chirwere che neuroleptic malignant syndrome (fivha yakanyanya, kuoma kwemhasuru, kuvhiringidzika)
• Tardive dyskinesia (kufamba kwemhasuru kusingadiwi, kunyanya kumeso)
• Kuderera kwakanyanya kwenhamba yemasero machena eropa
• Kutapukirwa, kunyanya muvanhu vasina nhoroondo yekutapukirwa
• Matambudziko akakomba echiropa ane ruvara rweyero rweganda kana maziso
• Mavhiri eropa kana matambudziko ekutenderera kweropa

Nepo izvi zvinokanganisa zvakanyanya zvisingawanzoitiki, kuziva nezvazvo kunokubatsira kuti urambe wakangwarira uye kutsvaga rubatsiro nekukurumidza kana zvichidikanwa. Chiremba wako achakutarisa nguva dzose kuti abate chero matambudziko angangovapo pakutanga.

Ndiani Asingafaniri Kutora Olanzapine-uye-Samidorphan?

Mishonga iyi haina kukodzera munhu wese, uye mamwe mamiriro ehutano kana mamiriro anoita kuti zvive zvine njodzi. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akuraira iyi musanganiswa.

Vanhu vane chirwere chechiropa chakakomba havafaniri kutora mushonga uyu nekuti zvese zvikamu zvinogadziriswa nechiropa. Saizvozvowo, kana iwe uchiziva allergy kune olanzapine, samidorphan, kana chero zvinhu zvisina basa mutableti, unofanirwa kudzivisa mushonga uyu.

Kana iwe uchitora mishonga yeopioid yekurapa kurwadziwa, iyi musanganiswa haigone kukodzera nekuti samidorphan inogona kuvharira mhedzisiro yeopioids. Chiremba wako achada kunyatso funga nezveimwe mishonga mumamiriro ezvinhu aya.

Vakadzi vane pamuviri kana vanoyamwisa vanoda kufunga kwakakosha, sezvo kuchengeteka kwemusanganiswa uyu panguva yekuzvitakura nekuyamwisa kusina kugadzwa zvizere. Mupi wako wehutano achayerera mabhenefiti achipesana nenjodzi dzinogona kuitika kana iwe uchironga kuva nepamuviri kana watove nepamuviri.

Olanzapine-uye-Samidorphan Zita reBrand

Zita remhando yemushonga uyu musanganiswa ndiLybalvi, inogadzirwa neAlkermes. Iyi ndiyo chete musanganiswa weolanzapine uye samidorphan inowanikwa muzvitoro muUnited States.

Lybalvi inouya mumhando dzakasiyana dzetableti kuti ikubvumire kuti uwane mushonga wako zvichienderana nezvaunoda uye mhinduro yako kumushonga. Chiremba wako achasarudza simba rakakodzera uye anogona kurigadzirisa nekufamba kwenguva.

Paunenge uchikurukura mushonga uyu nemupi wako wehutano kana muzvinemakemisi, unogona kuutaura nezita rawo re generic (olanzapine-uye-samidorphan) kana zita rawo remhando (Lybalvi). Mazwi ese ari maviri anoreva mushonga mumwe chete.

Zvimwe Zvinogona Kutsiva Olanzapine-uye-Samidorphan

Mishonga yakati wandei inogona kurapa schizophrenia uye bipolar disorder kana iyi musanganiswa isiri yakanaka kwauri. Zvimwe zvisiri zvechinyakare antipsychotics zvinosanganisira risperidone, quetiapine, aripiprazole, uye ziprasidone, imwe neimwe iine yayo profile yezvakanakira uye mhedzisiro.

Kune vanhu vanonyanya kunetseka nezvekuwedzera uremu, aripiprazole kana ziprasidone zvinogona kunge zviri zvimwe zvakanaka, sezvo zvichiwanzokonzera kuwedzera uremu kushoma pane olanzapine-based mishonga. Lurasidone imwe sarudzo inowanzoita kuti uremu husachinje.

Chiremba wako anogonawo kufunga nezve mood stabilizers senge lithium kana valproate ye bipolar disorder, kana nzira dzemusanganiswa dzinoshandisa mishonga yakawanda kuti uwane yakanakisa symptom control ine mashoma mhedzisiro.

Sarudzo yezvimwe zvinotsiva zvinoenderana nezviratidzo zvako zvakananga, nhoroondo yako yekurapa, mimwe mishonga yaunotora, uye zvaunofarira nezve mhedzisiro uye hurongwa hwekurapa.

Ko Olanzapine-uye-Samidorphan Zviri Nani Pane Olanzapine Yoga?

Kune vanhu vazhinji, olanzapine-uye-samidorphan inopa zvakanakira pamusoro pe olanzapine yoga, kunyanya maererano nekudzora uremu. Zvidzidzo zvekurapa zvinoratidza kuti musanganiswa uyu unowanzoita kuti uremu huwedzere kushoma pane olanzapine pachayo.

Zvakanakira zvepfungwa zvinoramba zvakafanana pakati pezvisarudzo zviviri, sezvo olanzapine iri iyo inoshanda inorapa zviratidzo zvako zveutano hwepfungwa. Kuwedzerwa kwe samidorphan kunonyanya kutarisisa nyaya yekuwanda uremu pasina kukanganisa kushanda kwe schizophrenia kana bipolar disorder.

Zvisinei, "zviri nani" zvinoenderana nemamiriro ako ega. Kana wanga wakagadzikana pa olanzapine yoga pasina kuwedzera uremu zvakanyanya, kuchinja hakungadiwi. Chiremba wako achakubatsira kuyera zvakanakira nenjodzi dzechisarudzo chimwe nechimwe.

Mubatanidzwa unodhura zvakanyanya pane generic olanzapine yoga, izvo zvingave zvakakosha zvichienderana nekavharidhe yako yeinishuwarenzi uye mamiriro ako emari.

Mibvunzo Inowanzo Bvunzwa Nezve Olanzapine-uye-Samidorphan

Ko olanzapine-uye-samidorphan yakachengeteka here ye diabetes?

Mishonga iyi inoda kunyatsotariswa kana uine chirwere cheshuga, sezvo olanzapine inogona kukanganisa mazinga eshuga yeropa. Nepo samidorphan ichigona kubatsira kuderedza mamwe maitiro emetabolic, vanhu vane chirwere cheshuga vachiri kuda kuongororwa kweshuga yeropa nguva dzose vachitora mubatanidzwa uyu.

Chiremba wako anogona kutarisa shuga yako yeropa kakawanda paunotanga mushonga uyu uye anogona kuda kugadzirisa mishonga yako ye diabetes. Mubatanidzwa hausi otomatiki usina kuchengeteka kune vanhu vane chirwere cheshuga, asi unoda kutariswa kwepedyo kwekurapa.

Ndoita sei kana ndikatora olanzapine-uye-samidorphan zvakanyanya netsaona?

Kana netsaona ukatora zvakawanda kupfuura chiyero chako chakanyorwa, taura nemupi wako wehutano kana kutonga chepfu nekukasira. Zviratidzo zve overdose zvinogona kusanganisira kurara zvakanyanya, kuvhiringidzika, kutaura kwakashata, kana kuoma kufema.

Usaedze kuzviita kurutsa kana kutora chero mimwe mishonga yekurwisa overdose. Tsvaga rubatsiro rwekurapa rwehunyanzvi nekukasira, uye uuye nebhodhoro remishonga newe kana ukaenda kukamuri rekukurumidzira.

Ndoita sei kana ndikakanganwa dose ye olanzapine-uye-samidorphan?

Kana ukakanganwa mushonga, utore paunorangarira, kunze kwekuti yava nguva yechirongwa chako chinotevera. Muchiitiko ichocho, siya mushonga wakakanganwa uye uenderere mberi nechirongwa chako chemazuva ese - usatore mishonga miviri panguva imwe chete.

Kukanganwa mishonga dzimwe nguva hakuzokonzeri matambudziko nekukasira, asi edza kuchengetedza kuenderana kuti uwane mhedzisiro yakanaka yekurapa. Funga nezvekuisa chiyeuchidzo chezuva nezuva pafoni yako kana kushandisa chirongwa chemishonga kuti zvikubatsire kurangarira.

Ndingamira rini kutora olanzapine-uye-samidorphan?

Usambomira kutora mushonga uyu kamwe kamwe usati wambotaura nemupi wezvehutano wako kutanga. Kumira kamwe kamwe kunogona kukonzera zviratidzo zvekubviswa uye kudzoka kwezviratidzo zvepfungwa zvinogona kuva zvakanyanya kupfuura zvisati zvaitika kurapwa.

Chiremba wako achakubatsira kugadzira chirongwa chekuderera zvishoma nezvishoma kana kumisa kwakakodzera. Maitiro aya anowanzo tora mavhiki akati wandei kana mwedzi, zvichienderana nekuti wanga uchitora mushonga kwenguva yakareba sei uye mhinduro yako pachako.

Ndinganwa doro ndichitora olanzapine-uye-samidorphan here?

Zvakanakisa kudzivisa doro uchitora mushonga uyu, sezvo zvinhu zvese zviri zviviri zvinogona kukonzera kurara uye dzungu. Kuasanganisa kunowedzera njodzi yako yekuwa, tsaona, uye kutadza kutonga.

Kana ukasarudza kunwa dzimwe nguva, ita zvishoma uye ziva nezvekuwedzera mhedzisiro. Gara uchikurukura kushandiswa kwedoro nemupi wako wezvehutano, sezvo vachigona kukurudzira kusadzivisa zvachose zvichienderana nemamiriro ako ehutano pachako.