Olaparib (inowanikwa nemuromo)
Mhando dzinowanikwa
Lynparza
Nezve mushonga uyu
Olaparib inoshandiswa semushonga wekuchengetedza muvarwere vane cancer yeiyovari yakakura, cancer yematumbu efallopian, kana cancer yeparitoneal yekutanga ine rudzi rwakati rwe gene yeBRCA isina kunaka yakawanikwa (germline) kana yakawanikwa (somatic). Chiremba wenyu achaongorora kuvapo kwe gene iyi. Inoshandiswa muvarwere vakagamuchira kurapwa kwakakwana kana kusina kukwana nemishonga ye cancer inobva ku platinum. Olaparib inoshandiswa pamwe chete nebevacizumab semushonga wekuchengetedza muvarwere vane cancer yeiyovari yakakura, cancer yematumbu efallopian, kana cancer yeparitoneal yekutanga ine rudzi rwakati rwe gene yeBRCA isina kunaka kana bvunzo yekenza ine genomic instability inonzi HRD. Chiremba wenyu achaongorora kuvapo kwe gene iyi. Inoshandiswa muvarwere vakagamuchira kurapwa kwakakwana kana kusina kukwana nemishonga ye cancer inobva ku platinum. Olaparib inoshandiswawo kurapa cancer yeiyovari, cancer yematumbu efallopian, kana cancer yeparitoneal yekutanga ine rudzi rwakati rwe gene yeBRCA isina kunaka yakawanikwa (germline) kana yakawanikwa (somatic) yakadzoka. Chiremba wenyu achaongorora kuvapo kwe gene iyi. Inoshandiswa muvarwere vakagamuchira kurapwa kwakakwana kana kusina kukwana nemishonga ye cancer inobva ku platinum. Olaparib inoshandiswawo kurapa cancer yemazamu ekutanga yeHER2-negative muvarwere vakarapwa nemimwe mishonga ye cancer. Inoshandiswa kana masero e cancer aine germline BRCA mutations. Chiremba wenyu achashandisa bvunzo chaiyo kutsvaga mutations idzi. Inopiwa kuvarwere mushure mekuvhiya kubvisa tumor. Olaparib inoshandiswawo kurapa cancer yemazamu metastatic (cancer yakapararira) yeHER2-negative muvarwere vakarapwa nemimwe mishonga ye cancer. Inoshandiswa kana masero e cancer aine germline BRCA mutations. Chiremba wenyu achashandisa bvunzo chaiyo kutsvaga mutations idzi. Olaparib inoshandiswawo semushonga wekuchengetedza muvarwere vane metastatic (cancer yakapararira) cancer yepancreas ine rudzi rwakati rwe germline BRCA gene isina kunaka, uyo chirwere chake chisingaiti progress uye vakarapwa nemishonga ye cancer inobva ku platinum kwemavhiki angangoita 16. Olaparib inoshandiswawo kurapa metastatic castration-resistant prostate cancer (cancer yeprostate yakapararira uye inoramba kurapwa kwemishonga kana kuvhiya kunoderedza testosterone) muvarwere vakarapwa nemimwe mishonga ye cancer (semuenzaniso, abiraterone, enzalutamide). Inoshandiswa kana masero e cancer aine rudzi rwakati rwe HRR gene isina kunaka yakawanikwa (germline) kana yakawanikwa (somatic). Chiremba wenyu achaongorora kuvapo kwe gene iyi. Olaparib inoshandiswa pamwe chete ne abiraterone uye prednisone kana prednisolone kurapa metastatic castration-resistant prostate cancer (cancer yeprostate yakapararira uye inoramba kurapwa kwemishonga kana kuvhiya kunoderedza testosterone) ine rudzi rwakati rwe gene yeBRCA isina kunaka yakawanikwa kana yakawanikwa. Chiremba wenyu achaongorora kuvapo kwe gene iyi. Mushonga uyu unowanikwa chete nechirango chechiremba wako. Chigadzirwa ichi chinowanikwa mumaitiro anotevera ekurapa:
Usati washandisa mushonga uyu
Pakusarudza kushandisa mushonga, ngozi dzokutora mushonga iyeye dzinofanira kuyeranidzwa nezvakanaka zvichaita. Iyi sarudzo iwe nesachiremba wenyu muchaita. Kune mushonga uyu, zvinotevera zvinofanira kufungwa: Udza chiremba wako kana wakambonzwa chero chirwere chisina kujairika kana chisina kujairika kumushonga uyu kana mimwe mishonga. Uyewo udza nyanzvi yako yehutano kana uine mamwe marudzi eallergies, akadai sekudya, dyes, preservatives, kana mhuka. Kune zvigadzirwa zvisingadiwe kuraira, verenga zvinyorwa zvepakiti kana zvinhu zvakanyatsonaka. Ongororo dzakakodzera hadzina kuitwa pane hukama hwezera kune migumisiro yeolaparib muvanhu vevana. Kuvimbika uye kushanda hazvina kusimbiswa. Ongororo dzakakodzera dzakaitwa kusvika pari zvino hadzina kuratidza matambudziko chaiwo echirwere chevakwegura aizoita kuti kushandiswa kweolaparib kuvanhu vakwegura kuve kwakaoma. Hapana ongororo dzakakwana muvakadzi dzekuona ngozi yemwana pakuita mushonga uyu panguva yekuyamwisa. Yera mabhenefiti anogona kuitika pamwe nengozi dzinogona kuitika usati watora mushonga uyu panguva yekuyamwisa. Kunyange zvazvo mimwe mishonga isingafaniri kushandiswa pamwe chete, mune dzimwe nguva mishonga miviri yakasiyana inogona kushandiswa pamwe chete kunyange kana kuwirirana kungavepo. Munyaya idzi, chiremba wako angada kuchinja chiyero, kana mamwe matanho angave achifanirwa. Paunenge uchitora mushonga uyu, zvakakosha kuti nyanzvi yako yehutano izive kana uri kutora chero mishonga iri pazasi apa. Kuwirirana kunotevera kwakasarudzwa zvichienderana nekuwanda kwazvo uye hazvisi zvese zvinosanganisirwa. Kushandisa mushonga uyu nechero mishonga inotevera kazhinji hakusi kukurudzirwa, asi kunogona kudiwa mune dzimwe nguzi. Kana mishonga yose ikanyorwa pamwe chete, chiremba wako angachinja chiyero kana kuti ungashandisa mushonga mumwe kana maviri. Mimwe mishonga haifaniri kushandiswa panguva yekudya kana pedyo nenguva yekudya kana kudya marudzi akati wandei ezvokudya sezvo kuwirirana kungavepo. Kushandisa doro kana fodya nemimwe mishonga kunogona zvakare kukonzera kuwirirana kuitika. Kuwirirana kunotevera kwakasarudzwa zvichienderana nekuwanda kwazvo uye hazvisi zvese zvinosanganisirwa. Kushandisa mushonga uyu nechero zvinotevera kazhinji hakusi kukurudzirwa, asi kungave kusina kukwanisika mune dzimwe nguva. Kana zvakashandiswa pamwe chete, chiremba wako angachinja chiyero kana kuti ungashandisa mushonga uyu, kana kukupa mirairo yakakosha pamusoro pekushandisa zvokudya, doro, kana fodya. Kuvapo kwemamwe matambudziko ehutano kunogona kukanganisa kushandiswa kwemushonga uyu. Ita shuwa kuti unoudza chiremba wako kana uine mamwe matambudziko ehutano, kunyanya:
Mashandisirwo aungaita mushonga uyu
Mishonga inoshandiswa kurapa kenza ine simba kwazvo uye inogona kuva nemigumisiro yakawanda. Usati washandisa mushonga uyu, ita shuwa kuti unonzwisisa njodzi dzese nemabhenefiti. Zvakakosha kuti ushande pedyo nachiremba wako panguva yekurapa kwako. Tora mushonga uyu chaizvo sezvakarayirwa nachiremba wako. Usatore zvakawanda, usatore kazhinji, uye usatore kwenguva yakareba kupfuura yakarayirwa nachiremba wako. Kuita izvozvo kunogona kuwedzera mukana wemigumisiro. Mushonga uyu unouya neGwara reMishonga. Verenga utevedzere mirairo iyi zvakanyatsonaka. Bvunza chiremba wako kana uine mibvunzo ipi neipi. Usachinje mafomu maviri emishonga iyi. Lynparza®makapsure nema tablets haasi akafanana uye ane mwero yakasiyana. Mimedza makapsure nema tablets ese. Usapwanyisa, kuputsa, kuchema, kuvhura, kana kuavhura. Usatore makapsure kana akaita sekukuvara kana akabuda. Unogona kutora mushonga uyu nechikafu kana usina. Kana uine kenza yepurasiti yepakutanga ine hormone receptor, unofanira kuramba uchitora mishonga yehomoni panguva yekurapa neLynparza®tablets. Chiremba wako anogona kukupawo mimwe mishonga (semuenzaniso, mushonga wegonadotropin-releasing hormone) panguva yekurapa kenza ye prostate neLynparza®tablets kana kuti unofanira kubviswa kwemasikati usati washandisa mushonga uyu. Usadya mazambiringa egirepufuru kana Seville, kana kunwa muto wemazambiringa egirepufuru kana Seville paunenge uchishandisa mushonga uyu. Mwero wemushonga uyu uchave wakasiyana kune varwere vakasiyana. Tevedza mirairo yechiremba wako kana mirairo iri parinenge. Ruzivo runotevera rinosanganisira chete mwero wepakati wemushonga uyu. Kana mwero wako wakasiyana, usauchinje kunze kwekunge chiremba wako akakuudza kuti uite izvozvo. Huwandu hwemushonga waunotora hunotsamira pakusimba kwemushonga. Uyewo, nhamba yemishonga yaunotora zuva rega rega, nguva inobvumirwa pakati pemishonga, uye nguva yaunotora mushonga zvinoenderana nedambudziko rehutano rauri kushandisa mushonga. Kana ukasapotsa mushonga uyu, siya mushonga wakarasika uye dzoka kune yako purogiramu yekupa mishonga. Usatore mishonga miviri panguva imwe chete. Chengetera kure nevana. Usachengetere mushonga wakapfuura zuva kana mushonga usingachadiwi. Bvunza nyanzvi yehutano hwako maitiro aunofanira kubvisa mishonga ipi neipi yausashandisi. Chengeta mushonga muhari yakavharwa pane tembiricha yekamuri, kure nekupisa, hunyoro, uye chiedza chakananga. Chengeta kuti usagande. Chengeta ma tablets mubhodhoro rayo rekutanga.