Chii chinonzi Olaratumab: Zvazvinoshandiswa, Mishonga, Mativi eMuviri, nezvimwe zvakawanda

Olaratumab mushonga wekenza wakakosha unobatsira masoja ako emuviri kurwisa mamwe marudzi esarcoma yenyama nyoro. Kurapa uku kunoitwa nemutsinga kunoshanda nekudzivisa mapurotini chaiwo anodiwa nemaseru ekenza kuti akure uye apararire mumuviri wako wese.

Kana iwe kana mumwe munhu waunoda akanyorerwa olaratumab, ungangove uine mibvunzo yakawanda yekuti inoshanda sei uye zvekutarisira. Mushonga uyu unomiririra sarudzo yakakosha yekurapa vanhu vanotarisana nesarcoma yenyama nyoro, uye kunzwisisa kuti inopinda sei muchirongwa chako chekutarisira kunogona kukubatsira kuti unzwe wakagadzirira uye wakavimbika mberi.

Chii chinonzi Olaratumab?

Olaratumab mushonga wekurapa unotarwa uyo wekirasi yemishonga inonzi monoclonal antibodies. Fungidzira sepurutini yakagadzirirwa zvakakosha inotsvaga uye inonamatira kune zvakanangwa zvakananga pamaseru ekenza, ichibatsira kuderedza kukura kwavo.

Mushonga uyu unopihwa kuburikidza neIV infusion, zvinoreva kuti unotumirwa zvakananga muropa rako kuburikidza nemutsinga. Mushonga uyu wakagadzirwa zvakanyanya kurapa sarcoma yenyama nyoro, rudzi rwekenza runokura munyama dzinobatanidza dzemuviri dzakaita semhasuru, tendons, uye mafuta.

Olaratumab inoshanda zvakasiyana nechemotherapy yechinyakare nekuti inotarisa nzira dzakatarwa dzinoshandiswa nemaseru ekenza kuti ararame uye awande. Iyi nzira yakatarwa inogona kuve yakapfava pamaseru ane hutano ichiri kurwisa kenza zvinobudirira.

Chii chinonzi Olaratumab chinoshandiswa?

Olaratumab inonyanya kushandiswa kurapa sarcoma yenyama nyoro isingagoni kubviswa nekuvhiyiwa kana yakapararira kune dzimwe nhengo dzemuviri. Chiremba wako anowanzo sanganisa mushonga uyu nemumwe mushonga unonzi doxorubicin kuti vagadzire chirongwa chekurapa chinoshanda zvakanyanya.

Sarcoma yematishu akapfava mhando dzekenza dzisingawanzoitika dzinogona kukura muzvikamu zvakasiyana zvemuviri wako, kusanganisira maoko ako, makumbo, chipfuva, kana dumbu. Mapundu aya anogona kuva nematambudziko kurapa nekuti anowanzo kukura munzvimbo dzisina kukwanisa kubviswa kwakakwana kwekuvhiya.

Oncologist wako angakurudzira olaratumab kana sarcoma yako yakwira kana kana yakadzoka mushure mekurapa kwapfuura. Mushonga uyu wakagadzirirwa vanhu vasina kugamuchira chemotherapy yeiyo yavo yakwira sarcoma yematishu akapfava kare.

Olaratumab Inoshanda Sei?

Olaratumab inoshanda nekudzivisa protein inonzi PDGFR-alpha (platelet-derived growth factor receptor alpha) iyo maseru ekenza anoshandisa kukura uye kugadzira midzi yeropa mitsva. Kana iyi protein yakavharwa, maseru ekenza anotambura kuwana zvinovaka muviri uye zviratidzo zvavanoda kuti vararame uye vazhinjike.

Mushonga uyu unoonekwa sekurapa kenza kwakasimba zvishoma kunoshanda zvakanyatsonaka kupfuura chemotherapy yechinyakare. Panzvimbo pekukanganisa maseru ese anokurumidza kukamukana mumuviri wako, olaratumab inonyanya kutarisisa nzira dzinoshandiswa nemaseru e sarcoma yematishu akapfava.

Mishonga iyi inobatsirawo kudzivirira kuumbwa kwemidzi yeropa mitsva inodyisa mapundu, maitiro anonzi angiogenesis. Nekucheka kupiwa kweropa uku, olaratumab inogona kubatsira kuderedza kukura kwemapundu uye kuita kuti mamwe marapirwo ashande zvakanyanya.

Ndinofanira Kutora Sei Olaratumab?

Olaratumab inopiwa se intravenous infusion muchipatara kana nzvimbo yekurapa kenza pasi pekutariswa kwechiremba. Hauzogone kutora mushonga uyu kumba, sezvo uchida kunyatso tarisa uye midziyo yakakosha yekutonga kwakakodzera.

Usati wapiwa infusion yako, timu yako yehutano inogona kukupa mishonga yekudzivirira maitiro ekuita allergic uye kuderedza mhedzisiro. Haufaniri kutsanya usati warapwa, asi kudya chikafu chakareruka pamberi kunogona kukubatsira kuti unzwe wakasununguka panguva ye infusion.

Kupinza mushonga kunowanzo tora maminitsi 60 padosi rekutanga uye kunogona kupfupiswa kusvika maminitsi 30 padosi rinotevera kana ukachigamuchira zvakanaka. Chikwata chako chekurapa chichatarisa zviratidzo zvako zvehutano uye chichatarisa chero maitiro panguva yekurapa.

Uchagamuchira olaratumab pamazuva akatarwa sechikamu chekutenderera kwako kwekurapa, kazhinji mazuva makumi maviri nerimwe oga oga. Chiremba wako achasarudza chirongwa chaicho zvichienderana nemamiriro ako ega uye kuti uri kupindura sei kurapa.

Ndingatore Olaratumab Kwenguva Yakareba Sei?

Kureba kwekurapa kweolaratumab kunosiyana zvakanyanya kubva kumunhu nemunhu uye kunoenderana nekuti kenza yako inopindura sei mushonga. Oncologist wako achatarisa nguva dzose mamiriro ako kuburikidza nekuongorora uye bvunzo dzeropa kuti aone kuti unofanirwa kuramba uchirapwa kwenguva yakareba sei.

Vanhu vazhinji vanogamuchira olaratumab kwemwedzi yakati wandei, asi vamwe vangada kurapwa kwegore kana kupfuura. Chiremba wako acharamba achipa mushonga chero bedzi kenza yako ichiramba yakagadzikana kana ichiramba ichidzikira, uye chero bedzi uchigamuchira zvakanaka mhedzisiro yacho.

Kana kenza yako ikamira kupindura olaratumab kana ukawana mhedzisiro yakakomba, chiremba wako achakurukura newe dzimwe nzira dzekurapa. Chinangwa ndechokugara uchitsvaga chiyero chakakodzera pakati pekurwisa kenza yako uye kuchengetedza hupenyu hwako.

Ndezvipi Zvakaipa ZveOlaratumab?

Kufanana nemishonga yese yekenza, olaratumab inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese achaiwana. Mhedzisiro yakawanda inogona kubatwa nekutarisirwa kwekurapa kwakakodzera uye rutsigiro kubva kuchikwata chako chehutano.

Mhedzisiro yakajairika yaungawana inosanganisira kuneta, kusvotwa, kuderedzwa kwechido, uye manyoka. Mhedzisiro iyi inowanzoita nyoro kusvika pakati nepakati uye inowanzoita nani muviri wako uchigadzirisa kurapwa.

Heano mhedzisiro inowanzoziviswa iyo varwere vanowana:

• Kuneta uye kushaya simba zvinogona kukanganisa mabasa ezuva nezuva
• Kurwadziwa mudumbu nekutsvuka, kunyanya mumazuva mashoma ekutanga mushure mekurapwa
• Kuderera kwechido chekudya uye shanduko mukunaka
• Manyoka kana kuvharika
• Kutetepa kwebvudzi kana shanduko mumhando yebvudzi
• Kurwadziwa kwemhasuru nemajoini
• Kutemwa nemusoro
• Kutadza kurara

Chikwata chako chehutano chichakupa mishonga uye nzira dzekukubatsira kudzora izvi zvinokonzeresa uye kuchengetedza kunyaradzwa kwako panguva yekurapwa.

Vamwe vanhu vanogona kusangana nezvimwe zvinokonzeresa zvakanyanya zvinoda kutariswa kwekurapa nekukurumidza. Kunyange izvi zvisingawanzoitiki, zvakakosha kuzviziva uye kufonera chiremba wako nekukurumidza kana zvikaitika.

Heano mamwe mativi akakomba anoda kutarisirwa kwekurapa nekukurumidza:

• Kusagadzikana kwakanyanya kwemuviri panguva kana mushure mekuiswa
• Matambudziko emoyo, kusanganisira kuderera kwebasa remoyo
• Manyoka akakomba asingapinduri kurapwa
• Zviratidzo zveutachiona senge fivha, kutonhora, kana kukosora kunoramba kuripo
• Kubuda ropa kusingaite kana kupwanya
• Kufema kwakaoma kana kurwadziwa muchipfuva
• Kuzvimba kwakanyanya mumaoko ako, tsoka, kana kumeso

Izvi zvinokonzeresa zvakanyanya hazviwanzoitiki, asi chikwata chako chekurapa chichakutarisa zvakanyanya panguva yekurapwa kuti ubate chero matambudziko nekukurumidza uye uagadzirise nekukurumidza.

Ndiani Asingafaniri Kutora Olaratumab?

Olaratumab haikodzeri munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akurudzira kurapwa uku. Vanhu vane mamwe mamiriro emoyo kana matambudziko akakomba echiropa vangave vasiri vakakodzera mushonga uyu.

Oncologist wako achada kuziva nezve chero matambudziko emoyo awakambove nawo, kusanganisira kukundikana kwemoyo, kurwisa kwemoyo, kana rhythm isina kujairika yemoyo. Sezvo olaratumab inogona kukanganisa basa remoyo, vanhu vane mamiriro emoyo aripo vangangoda kumwe kutariswa kana dzimwe nzira dzekurapa.

Kana wakazvitakura kana uchiyamwisa, olaratumab haikurudzirwi nekuti inogona kukuvadza mwana wako. Vakadzi vane makore ekubereka vana vanofanira kushandisa nzira dzinoshanda dzekudzivirira pamuviri panguva yekurapa uye kwemwedzi yakati wandei mushure meiyo dose yekupedzisira.

Vanhu vane zvirwere zvakakomba, zvinoshanda vanofanira kumirira kusvikira chirwere chichidzoreka vasati vatanga olaratumab. Immune system yako inogona kunge yakaderera zvishoma panguva yekurapa, zvichiita kuti zvive zvakaoma kurwisa zvirwere.

Zita reBrand reOlaratumab

Olaratumab inotengeswa pasi pezita rebrand rekuti Lartruvo. Iri ndiro zita rebrand chete riripo parizvino remushonga uyu, uye rinogadzirwa naEli Lilly and Company.

Paunogamuchira kurapwa kwako, uchaona

Mishonga yeImmunotherapy yakaita se pembrolizumab iri kudzidzwa mhando dze sarcoma uye inogona kuwanikwa kuburikidza nekuedzwa kwekiriniki. Chiremba wako anogona kukubatsira kuti uongorore kana chero zvidzidzo zviri kuenderera mberi zvingave zvakakodzera kune mamiriro ako.

Ko Olaratumab Ari Nani Kudarika Doxorubicin?

Olaratumab na doxorubicin vanoshanda zvakanyanya kana vakashandiswa pamwechete pane senzira dzekurapa dzinokwikwidzana. Zvidzidzo zvakaratidza kuti kusanganisa mishonga iyi kunogona kushanda zvakanyanya kupfuura kushandisa doxorubicin yega pakurapa sarcoma yenyama nyoro.

Doxorubicin imishonga yechinyakare yekemotheraphy yakashandiswa kwemakumi emakore kurapa marudzi akasiyana ekenza, kusanganisira sarcomas. Kunyangwe ichishanda, inogona kukonzera matambudziko akakosha, kunyanya kumoyo, uye ine miganho yezviyero.

Olaratumab inowedzera nzira yakatarwa kune mhedzisiro yakakura yekurwisa kenza ye doxorubicin. Kusanganiswa kunobvumira vanachiremba kurwisa maseru ekenza kuburikidza nenzira dzakawanda panguva imwe chete, zvichikwanisa kuvandudza mhedzisiro vachibata matambudziko.

Oncologist wako achafunga nezve mamiriro ako chaiwo, kusanganisira hutano hwako hwese, kushanda kwemoyo, uye kurapwa kwapfuura, pavanenge vachisarudza kana kurapa kwakabatanidzwa kwakakukodzera.

Mibvunzo Inowanzo Bvunzwa Nezve Olaratumab

Ko Olaratumab Akachengeteka Kune Vanhu vane Chirwere Chemoyo?

Olaratumab inoda kufungwa zvakanyanya kana uine matambudziko emoyo aripo. Mishonga inogona kukanganisa kushanda kwemoyo, saka chiremba wako anogona kuraira bvunzo dzemoyo usati watanga kurapwa uye achatarisa moyo wako nguva dzose panguva yekurapa.

Kana uine matambudziko emoyo akapfava, oncologist wako angaramba achikurudzira olaratumab nekutarisa pedyo uye pamwe nekugadzirisa dosing. Zvisinei, vanhu vane kukundikana kwemoyo kwakanyanya kana kurwisa kwemoyo kwemazuva ano vangada mamwe marapirwo.

Cardiologist wako uye oncologist vachashanda pamwechete kuti vaone nzira yakachengeteka yemamiriro ako chaiwo emoyo vachipa kurapwa kwekenza kunoshanda.

Ndingaita Sei Kana Ndakagamuchira Olaratumab Yakawandisa Netsaona?

Sezvo olaratumab ichipiwa munzvimbo yekurapa inodzorwa, overdoses netsaona hazviwanzoitika. Chikwata chako chehutano chinonyatsoverenga muyero wako zvichienderana nehuremu hwemuviri wako uye chinonyatsoongorora maitiro ekuisa.

Kana uine hanya nemuyero wako kana uine zviratidzo zvisingawanzoitiki panguva kana mushure mekurapwa, udza chikwata chako chekurapa nekukasira. Vanogona kuongorora mamiriro ako uye kupa hanya yakakodzera kana zvichidikanwa.

Vashandi vezvokurapa vanopa kurapwa kwako vakadzidziswa kubata chero matambudziko anogona kumuka uye vachakutarisa panguva yekuiswa.

Ndingaita Sei Kana Ndikakanganwa Dose yeOlaratumab?

Kana iwe ukakanganwa kugadzwa kweolaratumab, taura nehofisi yeoncologist yako nekukurumidza sezvinobvira kuti uise zvakare. Usamirira kusvika kugadzwa kwako kunotevera, sezvo kuchengetedza nguva yekurapa nguva dzose kwakakosha pakushanda.

Chikwata chako chehutano chichashanda newe kuti uwane kugadzwa kunotevera kunowanikwa kunokodzera chirongwa chako chekurapa. Vanogona kuda kugadzirisa chirongwa chako chekurapa zvachose zvichienderana nekuti kunonoka kwave kwenguva yakareba sei.

Mamiriro ehupenyu dzimwe nguva anoita kuti zvive zvakaoma kuchengeta kugadzwa kwega kwega, uye chikwata chako chekurapa chinonzwisisa izvi. Vachakubatsira kuti udzokere panzira nekurapwa kwako zvakachengeteka uye zvinobudirira sezvinobvira.

Ndingamira Rini Kutora Olaratumab?

Sarudzo yekumisa kurapwa kweolaratumab inofanira kugara ichiitwa mukubvunzana neoncologist yako. Iwe unowanzoenderera mberi nekurapwa chero bedzi kenza yako ichipindura zvakanaka uye iwe uchishivirira mhedzisiro yacho zvakanaka.

Chiremba wako achashandisa ma scans enguva dzose uye bvunzo dzeropa kuti aongorore kuti kenza yako iri kupindura sei kurapwa. Kana kenza yako ikamira kupindura kana kutanga kukura zvakare, vanogona kukurudzira kumisa olaratumab uye kuyedza imwe nzira.

Usambomira kurapwa olaratumab wega, kunyangwe uchinzwa zviri nani kana uchisangana nemigumisiro yakaoma. Chiremba wako wezve oncology anogona kubatsira kubata nemigumisiro uye achaita zvisarudzo zvekutarisira kurapwa zvichibva pane chirongwa chako chekuchengetwa kwekenza.

Ndingashanda here ndichitora Olaratumab?

Vanhu vazhinji vanoenderera mberi vachishanda vachigamuchira kurapwa kwe olaratumab, kunyangwe iwe ungada kuita zvimwe zvigadziriso kuchirongwa chako. Kuneta nemimwe migumisiro inogona kusiyana zvakanyanya kubva kumunhu nemunhu.

Sezvo kurapwa kazhinji kuchipiwa mumasvondo matatu ega ega, ungangoda kuronga infusions yako neChishanu kana pamberi pemavhiki ekuzorora mushure. Vanhu vazhinji vanowana vachinzwa vaneta kwemazuva mashoma mushure mekurapwa kwega kwega.

Taura nemushandirwi wako nezve kurongeka kwebasa kunochinjika kana zvichidikanwa, uye usazeze kukurukura mazinga ako esimba uye zvinokunetsa zvebasa nechikwata chako chekuchengetwa kwehutano. Vanogona kupa gwara uye rutsigiro rwekubatsira kuchengetedza mhando yehupenyu hwakanaka panguva yekurapwa.