Chii chinonzi Omadacycline: Zvinoshandiswa, Mishonga, Migumisiro Yakaipa uye Zvimwe

Omadacycline mushonga mutsva weantibiotic unobva kumhuri ye tetracycline yemishonga. Yakagadzirirwa kurwisa zvirwere zvakakomba zvebhakitiriya zvave zvichidzivirira kune mamwe maantibiotics, zvichiita kuti ive chishandiso chinokosha kana kurapwa kwetsika kusingashande zvakanaka.

Mushonga uyu unopiwa kuburikidza neIV (intravenous) mutsara zvakananga muropa rako, izvo zvinoita kuti risvike pakukwirira kwakanyanya mumuviri wako nekukurumidza. Chikwata chako chehutano chichakuchengeta zvakanyatsonaka panguva yekurapa kuti uve nechokwadi chekuti uri kupindura zvakanaka uye uchiona migumisiro mishoma yakaipa.

Chii chinonzi Omadacycline chinoshandiswa?

Omadacycline inorapa mhando mbiri huru dzezvirwere zvakakomba zvebhakitiriya. Yakanyatsogadzirirwa pneumonia yebhakitiriya yakawanikwa munharaunda uye acute bacterial skin uye skin structure infections kana mamwe maantibiotics angasashande.

Community-acquired bacterial pneumonia chirwere chemapapu chaunogona kubata kunze kwezvikoro zvekurapa kana nzvimbo dzekutarisira hutano. Rudzi urwu rwe pneumonia runogona kuve rakaoma kurapa nekuti bhakitiriya rinokonzera rinowanzoita kuramba kune maantibiotics anowanzo shandiswa.

Mushonga uyu unorapawo zvirwere zvakakomba zve skin uye soft tissue, kusanganisira cellulitis, abscesses, uye wound infections. Zvirwere izvi zvinogona kupararira nekukurumidza uye kuva njodzi yehupenyu kana zvikasabatwa nemushonga wakakodzera, ndosaka chiremba wako angasarudza omadacycline pazvinhu izvi zvakakomba.

Omadacycline inoshanda sei?

Omadacycline inoshanda nekumisa bhakitiriya kubva pakugadzira mapuroteni avanoda kuti vararame uye vazhinjike. Inoonekwa seantibiotic yakasimba nekuti inogona kukunda nzira dzakawanda dzekudzivirira bhakitiriya dzinoshandisa kuramba mamwe maantibiotics e tetracycline.

Funga nezvazvo semhando yepamusoro ye tetracycline antibiotics dzekare. Nepo mabhakitiriya akadzidza kurwisa akawanda maantibiotics echinyakare, omadacycline ine zvinhu zvakakosha zvinobatsira kuti ipfuure dziviriro idzi dzemabhakitiriya uye iite basa rayo nemazvo.

Mushonga uyu unotarisa ribosome yemabhakitiriya, iyo yakaita sefekitari diki mukati mebhakitiriya inogadzira mapuroteni akakosha. Nekuvhara fekitari iyi, omadacycline inonyanya kuita kuti mabhakitiriya anzwe nzara uye inovadzivisa kubereka, zvichibvumira immune system yako kuti ibvise hutachiona.

Ndingatora sei Omadacycline?

Omadacycline inopiwa chete kuburikidza neIV line nevashandi vehutano muchipatara kana kiriniki. Hauzotore mushonga uyu kumba, sezvo uchida kunyatsoongororwa uye kutariswa kwakakodzera kwekurapa panguva yekutarisira.

Madosi anowanzoitwa kamwe chete pazuva, uye infusion imwe neimwe inotora maminitsi makumi matatu kuti ipedze. Chikwata chako chehutano chichasarudza huwandu chaihwo zvichienderana nehuremu hwako, basa reitsvo, uye kuoma kwehutachiona hwako.

Haufanire kunetseka nezvekutora nechikafu kana mudumbu risina chinhu sezvo ichienda zvakananga muropa rako. Zvisinei, zvakakosha kuti ugare uine mvura yakawanda panguva yekurapa, saka inwa mvura yakawanda kunze kwekunge chiremba wako achikurudzira zvimwe.

Chikwata chako chekurapa chichakutarisa zvakanyanya panguva ye infusion yega yega kune chero maitiro ekukasira. Vachachengetawo rekodhi yekuti uri kupindura sei kurapwa kuburikidza nekutarisa nguva dzose uye pamwe bvunzo dzeropa.

Ndingatora Omadacycline kwenguva yakareba sei?

Kureba kwekurapa kunowanzoita mazuva manomwe kusvika gumi nemana, zvichienderana nerudzi uye kuoma kwehutachiona hwako. Chiremba wako achasarudza kureba chaiko kwekurapa zvichienderana nekuti unopindura nekukurumidza sei uye kuti muviri wako unobvisa sei hutachiona.

Kana uine pneumonia, ungada kurapwa kwemazuva 7 kusvika ku14, nepo zvirwere zvepaganda zvingada nguva yakafanana. Chikwata chako chehutano chichaongorora kufambira mberi kwako zuva rega rega uye chingachinja chirongwa chekurapa kana zvichidikanwa.

Zvakakosha kupedzisa nzira yese yekurapa, kunyangwe ukatanga kunzwa zviri nani usati wapedza. Kumisa mushonga weantibiotic nekukurumidza kunogona kubvumira mabhakitiriya akasara kuti awande zvakare uye pamwe kutanga kusadzivirirwa kumushonga.

Ndezvipi Zvakaipa ZveOmadacycline?

Semishonga yese, omadacycline inogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachizvigamuchira zvakanaka. Mhedzisiro yakajairika inowanzoita nyoro uye inogoneka nekuchengetwa kwakakodzera kwekurapa.

Heano mhedzisiro yaungasangana nayo, yakakamurwa nekuti inowanzoitika sei:

Mhedzisiro Yakajairika

Mhedzisiro iyi inoonekwa muvanhu vanopfuura 10% vachitora omadacycline:

• Kunyara nekutsvuka - Iyi ndiyo mhedzisiro inowanzoitika, ichikanganisa vanhu vanenge 1 kubva pa4
• Manyoka - Kazhinji nyoro asi dzimwe nguva inogona kuve yakanyanya
• Kuita kwenzvimbo yekujekesa - Kurwadziwa, kutsvuka, kana kuzvimba kwakaiswa IV
• Kutemwa nemusoro - Kazhinji nyoro uye kwenguva pfupi
• Kuneta - Kunzwa kuneta kupfuura zvakajairika panguva yekurapa

Mhedzisiro iyi yakajairika inowanzoita nani muviri wako paunojaira mushonga. Chikwata chako chehutano chinogona kupa kurapwa kubatsira kudzora kunyara kana zvimwe zviratidzo zvisinganzwisisike.

Mhedzisiro Isingawanzoitiki Asi Yakakosha

Dzimwe mhedzisiro dzinoitika kazhinji asi dzinofanirwa kutariswa:

• Manyoka inokonzerwa neClostridium difficile (CDAD) - Hutachiona hwakakomba hwematumbu hunogona kukura mazuva mashoma kusvika kumavhiki mushure mekurapwa
• Ma enzymes echiropa akakwira - Chiremba wako achatarisa izvi kuburikidza nemiedzo yeropa
• Kuverenga kwepakati kwemahwendefa eropa - Izvi zvinokanganisa kugona kweropa kuita bundu
• Dizziness kana lightheadedness - Kazhinji nyoro asi zvakakosha kuzivisa
• Kurwadziwa mudumbu - Kupfuura kusagadzikana mudumbu kwakajairika

Chikwata chako chekurapa chichatarisa mhedzisiro iyi kuburikidza nekutarisa nguva dzose uye kuyedzwa kweropa kana zvichidikanwa.

Mhedzisiro isingawanzoitiki Asi Yakakomba

Kunyange zvisingawanzoitiki, mamwe mhedzisiro yakakomba inoda kutariswa kwekurapa nekukurumidza:

• Maitiro akakomba ekuita allergic - Kuoma kufema, kuzvimba kwechiso kana huro, rash yakakomba
• Matambudziko akakomba echiropa - Kuita yero yeganda kana maziso, weti yakasviba, kuneta kwakanyanya
• Maitiro akakomba eganda - Rash yakapararira, blistering, kana ganda rinobva
• Intracranial hypertension - Kurwadziwa kwakanyanya kwemusoro, shanduko dzekuona, kana kuvhiringidzika
• Pancreatitis - Kurwadziwa kwakanyanya mudumbu kunogona kupararira kumusana

Izvi zvinokonzera mhedzisiro yakakomba hazviwanzoitiki, asi chikwata chako chehutano chakadzidziswa kuziva nekukurumidza uye kuzvibata kana zvikaitika.

Ndiani Asingafaniri Kutora Omadacycline?

Vanhu vakati wandei vanofanira kudzivisa omadacycline nekuda kwenjodzi dzakawedzera kana kushanda zvishoma. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa usati wanyora mushonga uyu.

Haufaniri kugamuchira omadacycline kana uine allergy inozivikanwa kune tetracycline antibiotics. Izvi zvinosanganisira allergies kune doxycycline, minocycline, kana chero mamwe mishonga mumhuri iyi, sezvo cross-reactions inogona kuitika.

Vakadzi vane pamuviri vanofanira kudzivisa mushonga uyu, kunyanya munguva yechipiri neyechitatu. Mishonga inorwisa mabhakitiriya yeTetracycline inogona kukanganisa mazino nemapfupa ari kukura mumwana ari mudumbu, zvichikonzera kusachinja ruvara zvachose kana matambudziko ekukura.

Vana vari pasi pemakore masere havafaniri kupiwa omadacycline nekuti inogona kukonzera kusachinja ruvara kwemazino zvachose uye kukanganisa kukura kwemapfupa. Zvisinei, mumamiriro ezvinhu anotyisidzira upenyu, vanachiremba vanogona kuyera zvakanakira nezvakaipa.

Ngozi Dzinokosha Dzinodiwa Kuti:

Vamwe vanhu vanogona kutora omadacycline asi vanoda kuongororwa zvakanyanya uye pamwe madosi akagadziridzwa:

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• Vanhu vane chirwere chakakomba cheitsvo - Dosing inogona kugadziriswa
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• Avo vane matambudziko echiropa - Inoda kuongororwa zvakanyanya kwekuita kwechiropa
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• Vamwe vanaamai vanoyamwisa - Mushonga unogona kupinda mumukaka wemazamu
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• Vanhu vane nhoroondo ye intracranial hypertension - Vanogona kunge vari panjodzi yakakura yekudzoka
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• Avo vanotora zvinoderedza ropa - Vanogona kuda kuongororwa nguva dzekuvhara
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Chikwata chako chehutano chichaongorora izvi uye kugadzirisa chirongwa chako chekurapa zvinoenderana kuti uve nechokwadi chekuchengeteka kwako.

Mazita eBrand eOmadacycline

Omadacycline inowanikwa pasi pezita rebrand Nuzyra muUnited States. Iri ndiro zita rekutanga rebrand rauchasangana naro munzvimbo zhinji dzehutano.

Mushonga uyu unogadzirwa neParatek Pharmaceuticals uye mutsva kumusika, wakabvumidzwa neFDA muna 2018. Nekuti mushonga mutsva unorwisa mabhakitiriya, shanduro dzakajairika hadzisati dziripo.

Paunogamuchira kurapwa, unogona kuona

Mamwe maantibayoti akawanda anogona kushandiswa sezvimwe zvingasarudzwa kune omadacycline, zvichienderana nehutachiona hwako chaihwo uye mamiriro ako ekurapa. Chiremba wako achasarudza sarudzo yakanakisa zvichienderana nemhedzisiro yetsika yebhakitiriya uye mamiriro ako ega.

Ye pneumonia, zvimwe zvingasarudzwa zvinogona kusanganisira mamwe maantibayoti akasimba se linezolid, vancomycin, kana ceftaroline. Imwe neimwe ine simba rakasiyana uye inosarudzwa zvichienderana nekuti ibhakitiriya ripi riri kukonzera hutachiona hwako uye kuti rinodzivisa sei kurapwa kwakasiyana.

Zvehutachiona hweganda, zvimwe zvingasarudzwa zvinogona kusanganisira daptomycin, clindamycin, kana mamwe ma tetracyclines senge doxycycline. Sarudzo inoenderana nekukomba kwehutachiona hwako uye kana bhakitiriya richidzivisa mamwe maantibayoti.

Chikwata chako chekuchengetedza hutano chinowanzoita bvunzo kuti chizive chaizvo kuti ibhakitiriya ripi riri kukonzera hutachiona hwako usati wasarudza nzira yakanakisa yekurapa. Izvi zvinovimbisa kuti unogamuchira antibiotic inonyanya kushanda yemamiriro ako chaiwo.

Ko Omadacycline Zviri Nani Kune Mamwe Maantibayoti Here?

Omadacycline haisi

Asi, nekuti itsva uye ine simba, omadacycline inowanzo chengeterwa zvirwere zvakakomba uko mamwe maantibiotics asina kushanda kana asingatarisirwi kushanda. Haisi nguva dzose sarudzo yekutanga yezvirwere zvese zvebhakitiriya.

Mibvunzo Inowanzo Bvunzwa Nezve Omadacycline

Q1. Omadacycline Yakachengeteka Here Kune Vanhu vane Chirwere cheItsvo?

Omadacycline inogona kushandiswa kune vanhu vane chirwere cheitsvo, asi inoda kunyatso tariswa uye pamwe kugadziriswa kwemadosi. Kusiyana nemamwe maantibiotics, inobviswa mumuviri nemigwagwa yakawanda, kwete itsvo chete.

Kana uine matambudziko eitsvo akapfava kusvika pakati nepakati, unogona kusada kugadzirisa chero dose. Zvisinei, vanhu vane chirwere cheitsvo chakakomba vanogona kuda kugadziridzwa kwemadosi kudzivirira mushonga kuti usavake mumuviri wavo.

Chiremba wako achatarisa kushanda kweitsvo yako kuburikidza nemiedzo yeropa pamberi uye panguva yekurapa. Vachagadzirisa dose yako kana zvichidikanwa kuti uve nechokwadi chekuti unowana huwandu hwakakodzera hwemushonga pasina njodzi yemigumisiro.

Q2. Ndingaita Sei Kana Ndichiwana Migumisiro Yakakomba?

Kana iwe ukawana migumisiro yakakomba senge kuoma kufema, rash yakakomba, kana kurwadziwa kwakanyanya mudumbu, zivisa timu yako yehutano nekukasira. Sezvo iwe uchigamuchira mushonga uyu munzvimbo yekurapa, rubatsiro runogara ruri pedyo.

Kune mamiriro ekukurumidzira senge maitiro akakomba ekuita allergic, timu yako yekurapa ichamisa infusion nekukasira uye ichapa kurapwa kwakakodzera. Vane mishonga nemidziyo yakagadzirira kubata mamiriro aya nekukurumidza uye nemazvo.

Kunyangwe zviratidzo zvisina kunyanya kukomba asi zvinonetsa senge kuramba uine mwoyo, kuneta kusinganzwisisike, kana shanduko mukuona zvinofanirwa kuziviswa nekukurumidza. Timu yako yehutano inogona kugadzirisa kurapwa kwako kana kupa rutsigiro rwekutarisira kukubatsira kuti unzwe wakasununguka.

Q3. Ndingatyaira kana Kushandisa Muchina Ndichitora Omadacycline?

Unofanira kudzivisa kutyaira kana kushandisa michina kana ukaona dzungu, kuneta, kana zvimwe zvinokonzera zvinogona kukanganisa kugona kwako kuita mabasa aya zvakachengeteka. Sezvo uri kugamuchira kurapwa kweIV, unogona kunge uri muchipatara.

Vamwe vanhu vanoona dzungu diki kana kuneta panguva yekurapwa, izvo zvinogona kukanganisa kubatana kwako uye nguva dzekuita. Zviri nani kuti mumwe munhu akutyairire kumba mushure memisangano yako yekurapwa.

Paunenge wapedza nzira yako yekurapwa uye chero mhedzisiro yave kupora, unogona kazhinji kutangazve mabasa ako akajairika sekutyaira. Zvisinei, taura nachiremba wako kuti uone kuti zvakachengeteka kuita izvi rini.

Q4. Ko Omadacycline ichashanda pamwe chete nemimwe mishonga yangu here?

Omadacycline inogona kushanda pamwe chete nemimwe mishonga, saka zvakakosha kuti uudze timu yako yehutano nezve mishonga yese yaunotora. Izvi zvinosanganisira mishonga inopiwa nachiremba, mishonga inotengwa pasina chiremba, uye zvinowedzera.

Mishonga inogona kushanda pamwe chete nemishonga inotetesa ropa senge warfarin, zvichikwanisa kuwedzera njodzi yako yekubuda ropa. Chiremba wako angangoda kuongorora nguva dzako dzekuvhara ropa zvakanyanya panguva yekurapwa.

Mishonga mimwe inoderedza acid mudumbu, senge antacids kana proton pump inhibitors, inogona kukanganisa kuti omadacycline inoshanda sei. Zvisinei, sezvo uri kuigamuchira intravenously, izvi zvinosangana hazvina basa zvakanyanya kupfuura nemishonga inorwisa mabhakitiriya yemuromo.

Q5. Ndichaziva sei kana kurapwa kuri kushanda?

Timu yako yehutano ichaongorora zviratidzo zvakati wandei kuti uone kana omadacycline iri kurapa hutachiona hwako zvinobudirira. Izvi zvinosanganisira kuvandudzwa muzviratidzo zvako, zviratidzo zvakakosha, uye mhedzisiro yelabhoritari.

Ye pneumonia, unogona kuona kufema kuri nyore, kuderedzwa kwemwaranzi, uye kushoma kukosora mukati memazuva mashoma ekutanga kurapwa. Kune zvirwere zvepaganda, unofanira kuona kuderedzwa kwetsvuku, kuzvimba, uye kurwadziwa panzvimbo yekutapukirwa.

Chikwata chako chekurapa chichateverawo zviyero zvakaita se tembiricha yako, huwandu hwemasero machena eropa, uye zvimwe zviratidzo zveutachiona kuburikidza nemiedzo yeropa. Izvi zvinobatsira kupa mufananidzo wakakwana wekuti uri kupindura sei kurapwa.