Pacritinib (inowanikwa nemuromo)
Mhando dzinowanikwa
Vonjo
Nezve mushonga uyu
Pacritinib inoshandiswa kurapa myelofibrosis yepakati kana yepangozi yakakwira, kusanganisira primary myelofibrosis, post-polycythemia vera myelofibrosis, uye post-essential thrombocythemia myelofibrosis. Myelofibrosis chirwere chinotyisa chemapfupa emusana chinoonekwa neaya maratidzo anotevera: spleen yakakura (splenomegaly), kukwenya kwakanyanya, fivha, kupererwa neperspiration usiku, kurasikirwa nehuremu, kurwadziwa kwemwongo, kana kuneta kwakanyanya kana kushaya simba. Pacritinib mushonga unodzora kinase unoshanda pane immune system. Uyu mushonga unowanikwa chete nechirongo chakabva kuna chiremba. Chigadzirwa ichi chinowanikwa mumaumbirwo anotevera emishonga:
Usati washandisa mushonga uyu
Pakusarudza kushandisa mushonga, ngozi dzokutora mushonga iyeye dzinofanira kuyeranidzwa nezvakanaka zvichaita. Iyi sarudzo iwe nechikamu chako muchaizoita. Kune mushonga uyu, zvinotevera zvinofanira kufungwa: Udza chiremba wako kana wakambonzwa chero mhinduro isinganzwisisiki kana yakaipa kune mushonga uyu kana mimwe mishonga. Uyewo udza nyanzvi yako yehutano kana uine mamwe marudzi eallergies, akadai sekudya, dyes, preservatives, kana mhuka. Kune zvigadzirwa zvisinganyorwi, verenga zvinyorwa zvepakeji kana zvinosanganiswa zvakanaka. Ongororo dzakakodzera hadzina kuitwa pane hukama hwezera kune migumisiro ye pacritinib muvanhu vevana. Kuvimbika uye kushanda hazvina kusimbiswa. Ongororo dzakakodzera dzakaitwa kusvika pari zvino hadzina kuratidza matambudziko chaiwo echirwere chevakwegura aizoita kuti kushandiswa kwe pacritinib muvakuru kusashande. Hapana ongororo dzakakwana muvakadzi dzekuona ngozi yemwana pakushandisa mushonga uyu panguva yekuyamwisa. Yera mabhenefiti anogona kuitika pamwe nengozi dzinogona kuitika usati watora mushonga uyu panguva yekuyamwisa. Kunyange zvazvo mimwe mishonga isingafaniri kushandiswa pamwe chete, mune mamwe mamiriro mishonga miviri yakasiyana inogona kushandiswa pamwe chete kunyange kana kuwirirana kungavepo. Mumamiriro ezvinhu aya, chiremba wako angada kuchinja chiyero, kana mamwe matanho angave achidiwa. Paunenge uchitora mushonga uyu, zvakakosha kuti nyanzvi yako yehutano izive kana uri kutora chero mishonga iri pazasi. Kuwirirana kunotevera kwakasarudzwa zvichienderana nekuwanda kwazvo uye hazvisi zvese zvinosanganisirwa. Kushandisa mushonga uyu nechero mishonga inotevera hakusi kukurudzirwa. Chiremba wako angasarudza kusakubata nemushonga uyu kana kuchinja mimwe mishonga yaunotora. Kushandisa mushonga uyu nechero mishonga inotevera kazhinji hakusi kukurudzirwa, asi kunogona kudiwa mune zvimwe zviitiko. Kana mishonga yose ikanyorwa pamwe chete, chiremba wako angachinja chiyero kana kuti ungashandisa imwe kana ese mishonga. Mimwe mishonga haifaniri kushandiswa panguva yekudya kana pedyo nenguva yekudya kana kudya marudzi akati wandei ezvokudya sezvo kuwirirana kungavepo. Kushandisa doro kana fodya nemimwe mishonga kunogona zvakare kukonzera kuwirirana kuitika. Kuwirirana kunotevera kwakasarudzwa zvichienderana nekuwanda kwazvo uye hazvisi zvese zvinosanganisirwa. Kushandisa mushonga uyu nechero zvinotevera kazhinji hakusi kukurudzirwa, asi kungasakwanisiki mune zvimwe zviitiko. Kana zvakashandiswa pamwe chete, chiremba wako angachinja chiyero kana kuti ungashandisa mushonga uyu, kana kukupa mirairo yakakosha pamusoro pekushandisa zvokudya, doro, kana fodya. Kuvapo kwemamwe matambudziko ehutano kunogona kukanganisa kushandiswa kwemushonga uyu. Ita shuwa kuti unoudza chiremba wako kana uine mamwe matambudziko ehutano, kunyanya:
Mashandisirwo aungaita mushonga uyu
Tora mushonga uyu chete sezvakarayirwa nachiremba wako. Murapo wako unotsamira pane huwandu hwemaplatelet ako uye unofanirwa kuchinjwa kanopfuura kamwe kuti uwane zvinokushandira zvakanaka. Usashandise mushonga wakawanda, usashandise kazhinji, uye usashandise kwenguva yakareba kupfuura yakarayirwa nachiremba wako. Mushonga uyu unouya nechiratidzo chemashoko ekurapa. Verenga utevedzere mirairo zvakanyatsonaka. Bvunza chiremba wako kana uine mibvunzo. Ramba uchishandisa mushonga uyu chero nguva yakakuudza chiremba wako. Usachinje murapo wako kana kurega kutora mushonga uyu usati wataura nachiremba wako. Tora mushonga uyu uchidyisa kana usina kudya. Dya kapusuru yacho yose. Usavhure, usaputsa, kana kucheka. Tora mushonga uyu panguva imwe chete zuva rega rega. Kana uri kushandisa vamwe kinase inhibitors, chiremba wako angagadzira murapo wako kana kurega kutora mamwe kinase inhibitor mishonga usati watanga kurapwa ne pacritinib. Murapo wemushonga uyu uchave wakasiyana kune varwere vakasiyana. Tevedza mirairo yechiremba wako kana mirairo iri parinenge. Mashoko anotevera anosanganisira chete avhareji doses yemushonga uyu. Kana murapo wako wakasiyana, usauchinje kunze kwekunge chiremba wako akuudza kudaro. Huwandu hwemushonga waunotora hunotsamira pakasimba kwemushonga. Uyewo, nhamba ye doses yaunotora zuva rega rega, nguva inobvumirwa pakati pe doses, uye nguva yaunotora mushonga zvinoenderana nedambudziko rekurapa rauri kushandisa mushonga. Kana ukasapotsa dose yemushonga uyu, siya dose yakarasika uye dzokera kune yako dosing schedule. Usapindise doses. Chengetedza mushonga mubhodhoro rakavharwa pane tembiricha yekamuri, kure nekupisa, hunyoro, uye chiedza chakananga. Chengetedza kuti urege kuomarara. Chengetedza kure nevana. Usachengetse mushonga wakapfuura zuva kana mushonga usingachadiwi. Bvunza nyanzvi yako yekuchengetedza utano maitiro aunofanira kubvisa chero mushonga wausashandisi.