Chii chinonzi Palonosetron: Zvinoshandiswa, Madosi, Migumisiro Yemuviri uye Zvimwe

Palonosetron mushonga unopiwa nemurairo wechiremba unopiwa kuburikidza nemutsipa (intravenous) kudzivirira kusvotwa nekutsvuka. Yakagadzirirwa kubatsira vanhu vari kuwana chemotherapy kana kuvhiyiwa kunowanzoita zviratidzo izvi zvisingafadzi. Mushonga uyu unoshanda nekudzivisa zviratidzo zvakasiyana-siyana muuropi hwako zvingaita kuti unzwe kurwara mudumbu rako.

Chii chinonzi Palonosetron?

Palonosetron ndeyeboka remishonga inonzi 5-HT3 receptor antagonists, izvo zvinoita sezvakaoma asi zvinongoreva kuti inodzivisa vatumwa vemakemikari mumuviri wako. Vatumwa ava, vanonzi serotonin, vanogona kukonzera kusvotwa nekutsvuka kana vakasunungurwa muhuwandu hukuru panguva yekurapa kwekurapa. Funga nezve palonosetron sechivharo chinodzivirira chinodzivirira zviratidzo izvi zvisingadiwi kuti zvisvike pachikamu cheuropi hwako chinodzora kusvotwa.

Mushonga uyu unowanikwa chete sejojo uye unofanirwa kupiwa nenyanzvi yehutano munzvimbo yekurapa. Hauzive kutora palonosetron kumba kana nemuromo - yakagadzirirwa zvakanyanya kushanda kuburikidza neropa rako kana ichipiwa intravenously.

Palonosetron Inoshandiswa Kunei?

Palonosetron inonyanya kushandiswa kudzivirira kusvotwa nekutsvuka kunokonzerwa nekurapa kwekenza chemotherapy. Mishonga yakawanda yechemotherapy inogona kukonzera kuti unzwe kurwara zvakanyanya, uye mushonga uyu unobatsira kuchengeta zviratidzo izvozvo kuitira kuti ugone kutarisa kurapwa kwako nekupora. Inonyanya kushanda pakudzivirira kusvotwa nekukurumidza (mukati me24 maawa ekutanga) uye kusvotwa kwakanonoka (iyo inogona kuitika mazuva mushure mekurapa).

Mushonga uyu unoshandiswawo kudzivirira kusvotwa nekutsvuka mushure mekuvhiyiwa, kunyanya kana anesthesia yakajairika ichishandiswa. Vamwe vanhu vanowanzo svotwa mushure mekuvhiyiwa, uye palonosetron inogona kubatsira kuti kupora kwako kuve kwakanyanya kugadzikana. Chiremba wako achasarudza kana iwe uri munhu akakodzera mushonga uyu zvichibva pane chirongwa chako chekurapa uye nhoroondo yako yezvokurapa.

Palonosetron Inoshanda Sei?

Palonosetron inoshanda nekudzivisa serotonin receptors munzvimbo mbiri dzakakosha dzemuviri wako: hurongwa hwako hwekugaya chikafu uye nzvimbo chaiyo muuropi hwako inonzi chemoreceptor trigger zone. Kana mishonga yekemotherapy kana anesthesia yapinda mumuviri wako, inogona kukonzera muviri wako kuti ubudise huwandu hukuru hwe serotonin, iyo inowanzoita chiratidzo muuropi hwako kuti itange kusvotwa nekutsvuka semhinduro yekudzivirira.

Mushonga uyu unoonekwa seune simba uye unoshanda zvakanyanya kana uchienzaniswa nemishonga yekare yekurwisa kusvotwa. Iine mhedzisiro inogara kwenguva refu, zvinoreva kuti iwe unowanzo shandisa madosi mashoma kuti urambe wakachengetedzwa kubva kusvotwa. Mushonga unotanga kushanda mukati memaminitsi makumi matatu ekutarisirwa uye unogona kupa dziviriro kwemazuva akati wandei, zvichienderana nemhinduro yako pachako.

Ndingatora Sei Palonosetron?

Hauzozvitore iwe pachako palonosetron - inotungamirirwa nemukoti kana chiremba kuburikidza neIV line muruoko rwako. Mushonga unopihwa sejojo rinononoka kwemasekonzi anenge makumi matatu, kazhinji maminitsi makumi matatu usati watanga kurapwa kwako kwekemotherapy kana usati waenda mukuvhiyiwa. Nguva yacho yakakosha nekuti inobvumira mushonga kuti usvike pamatanho anoshanda muropa rako kurapwa kunotanga kusvotwa.

Hamufaniri kuita chero chinhu chakakosha kuti mugadzirire jekiseni, uye hamufaniri kudzivisa chikafu kana zvinwiwa pamberi. Muchokwadi, kuva nechinhu chakareruka mudumbu mako zvinogona kukubatsira kuti unzwe wakasununguka zvachose. Chikwata chako chekuchengetedza hutano chichakutarisa iwe panguva uye mushure mejekiseni kuti uve nechokwadi chekuti uri kupindura zvakanaka kumushonga.

Ndingatora Palonosetron Kwenguva Yakareba Sei?

Kureba kwekurapa palonosetron kunoenderana zvachose nemamiriro ako chaiwo ekurapa. Kune varwere vechemotherapy, iwe unowanzo gamuchira chiyero chimwe chete pamberi pechikamu chega chega chekurapa mukati mechemotherapy yako. Izvi zvinogona kureva kuigamuchira vhiki nevhiki, mumasvondo mashoma, kana pane chero hurongwa hwakarongwa nachiremba wako weoncologist wekurapa kenza yako.

Kune varwere vekuvhiyiwa, iwe unowanzo gamuchira chiyero chimwe chete pamberi pekuvhiyiwa kwako, uye chiyero chimwe chete ichocho chinowanzoita kuti udzivise kusvotwa mushure mekuvhiyiwa. Zvisinei, kana uri kuvhiyiwa kakawanda kana maitiro akawedzerwa, chiremba wako angakurudzira mamwe madosi. Chikwata chako chekuchengetedza hutano chichagadzira chirongwa chakagadzirirwa iwe zvichienderana nehurongwa hwako hwekurapa uye kuti uri kupindura zvakanaka sei kumushonga.

Ndezvipi Zvakaipa ZvePalonosetron?

Vanhu vazhinji vanotsungirira palonosetron zvakanaka, asi semushonga chero upi zvake, unogona kukonzera zvimwe zvinokuvadza. Mashoko akanaka ndechokuti zvinokuvadza zvakakomba hazviwanzoitiki, uye mabhenefiti ekudzivirira kusvotwa kwakanyanya anowanzo kudarika njodzi.

Heano mativi akajairika aunogona kusangana nawo, uchifunga kuti vanhu vazhinji havana mativi zvachose:

• Kurwadziwa nemusoro (uyu ndiwo mhedzisiro inowanzozivikanwa)
• Kuvharika kana shanduko mukufamba kwematumbo
• Dizziness kana kunzwa lightheaded
• Kuneta kana kunzwa kuneta kupfuura zvakajairika
• Kurwadziwa kudiki kana kutsamwa panzvimbo yejekiseni

Mhedzisiro iyi inowanzoita nyoro uye yenguva pfupi. Chikwata chako chehutano chinoziva maitiro ekuvatarisira kana vakaitika, saka usazeze kutaura chero kusagadzikana kwaunonzwa.

Kune dzimwe mhedzisiro isingawanzoitiki asi yakakomba iyo inoda kutariswa kwekurapa nekukurumidza. Kunyange izvi zvisingaitike kazhinji, zvakakosha kuziva nezvazvo:

• Kusagadzikana kwakanyanya kune allergy (kunetsa kufema, kuzvimba kwechiso kana huro, rash yakanyanya)
• Kuchinja kukuru mumoyo rhythm (kurova kwemoyo kusingaite, kurwadziwa muchipfuva)
• Kuvharika kwakanyanya kwemudumbu kusingavandudzi nekutariswa
• Kuchinja kwemafungiro asinganzwisisike kana kufara
• Dizziness yakanyanya kana kufenda

Kana iwe ukasangana nechero zviratidzo izvi zvisingawanzoitiki, chikwata chako chekurapa chichazvigadzirisa nekukurumidza. Rangarira, uri munzvimbo yekurapa paunogamuchira mushonga uyu, saka rubatsiro runogara ruri pedyo.

Ndiani Asingafaniri Kutora Palonosetron?

Palonosetron inowanzoita safe kune vanhu vazhinji, asi kune dzimwe nguva apo chiremba wako angasarudza mumwe mushonga panzvimbo. Unofanira kuudza chikwata chako chehutano nezve mamiriro ako ese ekurapa nemishonga usati wagamuchira palonosetron kuti uve nechokwadi chekuti ndiyo sarudzo yakakunakira.

Chiremba wako achanyatso chenjerera nezvekupa palonosetron kana uine chero mamiriro aya:

• Kuzivikanwa allergy ku palonosetron kana mishonga yakafanana
• Matambudziko emoyo rhythm kana nhoroondo yemhuri yemamwe mamiriro emoyo
• Kusagadzikana kwakanyanya kwematsvo kana chiropa
• Kusagadzikana kweElectrolyte (kunyanya potassium yakaderera kana magnesium)
• Kushandiswa kwazvino kwemimwe mishonga inokanganisa rhythm yemoyo

Kuzvitakura nekuyamwisa kunoda kutariswa kwakakosha, kunyangwe palonosetron dzimwe nguva inogona kushandiswa kana mabhenefiti achipfuura njodzi. Chiremba wako achakurukura izvi newe kana zvichishanda kumamiriro ako.

Palonosetron Mazita eBrand

Palonosetron inowanikwa pasi pezita rekuti Aloxi, iro riri iro rinowanzo shandiswa muzvipatara uye nzvimbo dzekurapa. Unogonawo kuona richinzi nezita raro re generic, palonosetron hydrochloride, pamagwaro ekurapa kana ruzivo rwemishonga.

Dzimwe nzvimbo dzinogona kushandisa mazita akasiyana emhando kana ma generic, asi ese ane chinhu chimwe chete chinoshanda uye anoshanda nenzira imwechete. Chikwata chako chehutano chichakuzivisa kuti ndeipi vhezheni chaiyo yaunogamuchira, kunyangwe zita remhando kazhinji harikanganisi kuti mushonga unoshanda sei kudzivirira kusvotwa.

Zvimwe Zvinhu Zvokutsiva Palonosetron

Kana palonosetron isina kukodzera iwe, kune mamwe mishonga yakati wandei inoshanda yekurwisa kusvotwa iyo chiremba wako anogona kufunga. Imwe neimwe ine zvainobatsira uye inogona kushanda zviri nani kune vanhu vakasiyana kana mamiriro ezvinhu akasiyana.

Zvimwe zvakajairika zvinotsiva zvinosanganisira:

• Ondansetron (Zofran) - imwe 5-HT3 receptor antagonist inoshanda zvakafanana asi ine nguva shoma
• Granisetron (Kytril) - zvakare mukirasi imwechete yemishonga ine nguva yakasiyana zvishoma
• Dolasetron (Anzemet) - imwe sarudzo mumhuri imwechete yemishonga
• Metoclopramide (Reglan) - inoshanda kuburikidza nemaitiro akasiyana uye inogona kusanganiswa nemimwe mishonga
• Dexamethasone - steroid inogona kushanda zvakanyanya pakusvotwa kunokonzerwa nechemotherapy

Chiremba wako achasarudza imwe nzira yakanakisa zvichienderana nemamiriro ako chaiwo ekurapa, mamwe mishonga yaunotora, uye maitiro ako kumishonga yekurwisa kusvotwa munguva yakapfuura. Dzimwe nguva, kusanganiswa kwemishonga yakasiyana kunoshanda zvirinani pane chero mushonga mumwe chete.

Ko Palonosetron Ari Nani Kupfuura Ondansetron Here?

Zvese palonosetron ne ondansetron mishonga yakanaka yekudzivirira kusvotwa, asi vane misiyano yakakosha inogona kuita kuti imwe yakakodzera mamiriro ako. Palonosetron inowanzo gara kwenguva refu mumuviri wako, izvo zvinoreva kuti iwe unowanzo shandisa madosi mashoma uye uwane dziviriro yakareba kubva mukusvotwa.

Palonosetron inowanzo sarudzwa ye highly emetogenic (inokonzera kusvotwa) chemotherapy nekuti inopa dziviriro iri nani pakusvotwa kwakanonoka kunogona kuitika mazuva 2-5 mushure mekurapa. Ondansetron inoshanda zvakanaka pakusvotwa kwakare, asi inogona kusagara kwenguva refu. Zvisinei, ondansetron yakashandiswa kwemakore mazhinji uye ine rekodhi yakakura yekuchengeteka, pamwe inowanikwa mumhando dzakawanda dzinosanganisira mahwendefa uye mitsetse inonyungudika yemuromo.

Chiremba wako achafunga nezvezvinhu zvakaita serudzi rwechemotherapy yaunogamuchira, nhoroondo yako yezvokurapa, uye inishuwarenzi yako paunenge uchisarudza pakati pemishonga iyi. Zvese zviri zviviri zvinoshanda zvakanyanya, uye sarudzo

Ndingaita Sei Kana Ndakagamuchira Palonosetron Yakawandisa Netsaona?

Sezvo palonosetron ichipiwa nenyanzvi dzehutano munzvimbo yekurapa, kuwandisa netsaona hakusi kwakajairika. Mushonga unoyereswa zvakanyatsonaka uye unopiwa zvinoenderana nemitemo yakasimba. Zvisinei, kana uine hanya yekuti ungave wakagamuchira yakawanda, udza mukoti wako kana chiremba wako nekukasira.

Zviratidzo zvingaratidza kuti wakagamuchira mushonga wakawanda zvinosanganisira dzungu rakanyanya, rhythm yemoyo isingajairiki, kuneta kwakanyanya, kana chero zviratidzo zvinoita sezvakaipa kupfuura zvaitarisirwa. Chikwata chako chekurapa chakadzidziswa kuziva nekugadzirisa mamiriro aya nekukurumidza. Rangarira, uri munzvimbo yekurapa yakachengeteka uko rubatsiro runowanikwa nekukasira kana zvichidikanwa.

Ndingaita Sei Kana Ndakakanganwa Dose yePalonosetron?

Kukanganwa dose ye palonosetron kazhinji hakusi chinhu chaunofanira kunetseka nacho nekuti inopiwa sechikamu chekurapa kwako kwakarongeka. Kana ukakanganwa musangano wechemotherapy kwaunofanira kugamuchira palonosetron, taura nechikwata chako cheoncology kuti urongezve nekukasira.

Kune varwere vekuvhiyiwa, kana maitiro ako akanonoka kana kurongwa patsva, chikwata chako chekurapa chichagadzirisa nguva ye dose yako ye palonosetron zvinoenderana. Usaedze kugadzirisa dose yakakanganwa wega - gara uchishanda nevapi vehutano vako kuti uone nzira yakanakisa yekuita. Vanogona kukurudzira mishonga inopesana nekunzwa kusvotwa kana zvichidikanwa uchimirira kurapwa kwako kwakarongwa patsva.

Ndingamira Rini Kutora Palonosetron?

Uchamira kugamuchira palonosetron kana usisadi kurapwa kwekurapa kunoda dziviriro yekurwisa kusvotwa. Kune varwere vechemotherapy, izvi zvinowanzoita zvinoreva kana wapedza nzira yako yese yekurapa kenza. Kune varwere vekuvhiyiwa, iwe unowanzoita dose imwe chete, saka "kumira" kunoitika zvakasikwa mushure mekuvhiyiwa kwako.

Chiremba wako achakuzivisa paunenge usingachadi palonosetron sechikamu chechirongwa chako chekurapa. Kusiyana nemimwe mishonga inoda kuderedzwa zvishoma nezvishoma, palonosetron inogona kumiswa nekukasira pasina chero nzira yekuderedza. Kana uchiri kunzwa kusvotwa mushure mekupedza kurapwa kwako kwekutanga, chiremba wako angakurudzira mishonga yakasiyana iyo yakakodzera kushandiswa kwenguva refu.

Ndingagona here kutyaira mushure mekutambira Palonosetron?

Palonosetron inogona kukonzera dzungu kana kurara mune vamwe vanhu, saka kazhinji hazvikurudzirwi kutyaira nekukasira mushure mekutambira mushonga. Sezvo iwe uchigamuchira palonosetron sechikamu chechemotherapy kana kurapwa kwekuvhiya, ungangove uine marongero ekufambisa akagadzirirwa.

Nzvimbo zhinji dzekurapa dzinokurudzira kuva nemumwe munhu anokutyaira kumba mushure mekutambira chemotherapy kana kuvhiyiwa, zvisinei nemushonga wekurwisa kusvotwa unoshandiswa. Mirira kusvikira wanzwa wakamuka zvizere uye akatsiga usati watyaira, izvo zvinogona kuva maawa akati wandei kana kunyange zuva rinotevera zvichienderana nemamwe marapirwo ako. Kana usina chokwadi, bvunza chikwata chako chehutano kuti uwane gwara rakatarwa zvichienderana nemamiriro ako ega uye mhinduro kumushonga.