Chii chinonzi Pegaptanib: Zvayakashandiswa, Mishonga, Mativi eMuviri uye Zvimwe

Pegaptanib mushonga wemaziso wakakosha unobatsira kunonotsa kurasikirwa kwekuona muvanhu vane wet age-related macular degeneration (AMD). Mamiriro aya anoitika apo tsinga dzisina kujairika dzeropa dzinokura kuseri kweretina, zvichikonzera kubuda kwemvura uye matambudziko ekuona. Pegaptanib inoshanda nekudzivisa protein inonzi VEGF iyo inokurudzira tsinga idzi dzinokuvadza dzeropa kukura, ichibatsira kuchengetedza kuona kwako kwepakati.

Chii chinonzi Pegaptanib?

Pegaptanib mushonga unojekeswa wakagadzirirwa kurapa wet age-related macular degeneration. Iyo ndeyeboka remishonga inonzi anti-VEGF agents, zvinoreva kuti inovharisa vascular endothelial growth factor - protein inokurudzira kukura kwetsinga dzeropa.

Chiremba wako anojekesa mushonga uyu zvakananga mujeri re vitreous mukati meziso rako achishandisa tsono yakatetepa. Maitiro acho anonzi intravitreal injection, uye kunyangwe zvichigona kurira zvinonetsa, chaizvoizvo kurapwa kwemurwere kunoitwa nguva dzose. Mushonga unogara uchishanda muziso rako kwemavhiki akati wandei, uchishanda nguva dzose kudzivirira kumwe kukura kwetsinga dzeropa uye kubuda kwemvura.

Pegaptanib yaive imwe yemishonga yekutanga ye anti-VEGF yakatenderwa kurapwa kweAMD, kunyangwe sarudzo itsva dzichishandiswa zvakanyanya. Yakagadzirirwa kunangana neimwe chete fomu yeVEGF, ichiita kuti ive kurapwa kwakasarudzwa zvakanyanya kana ichienzaniswa nemimwe mishonga iri muchikamu ichi.

Chii chinonzi Pegaptanib chinoshandiswa?

Pegaptanib inonyanya kushandiswa kurapa wet age-related macular degeneration, mamiriro ezvinhu akakomba emaziso anogona kukonzera kurasikirwa kwekuona nekukurumidza. Iyi fomu yeAMD inokanganisa macula yako, chikamu chepakati peretina yako chine basa rekuona kwakapinza, kwakadzama kunodiwa pakuverenga, kutyaira, uye kuziva zviso.

Mushonga uyu unonyatso ratidzwa kuita ne neovascular AMD, zvinoreva kuti tsinga itsva dzeropa dziri kukura kwadzasina kukodzera. Tsinga idzi dzisina kujairika dzinobudisa mvura neropa, zvichikonzera kuzvimba uye mavanga anogona kukuvadza zvachose kuona kwako kwepakati. Pegaptanib inobatsira kunonotsa maitiro aya nekuderedza zviratidzo zvekukura zvinokurudzira tsinga dzeropa idzi dzine matambudziko.

Nepo pegaptanib ichigona kubatsira kuchengetedza kuona kwakatoitika uye kunonotsa kurasikirwa kwekuona, zvakakosha kunzwisisa kuti kazhinji haidzore kuona kwakatokanganiswa. Chinangwa ndechekugadzikana uye kudzivirira kuwedzera kuipa pane kuvandudza kuona kwazvino.

Pegaptanib Inoshanda Sei?

Pegaptanib inoshanda nekudzivisa VEGF-165, protein chaiyo inoratidza muviri wako kuti ukure tsinga itsva dzeropa. Mumaziso ane hutano, protein iyi inobatsira kuchengetedza basa retsinga dzeropa, asi mu wet AMD, inova overactive uye inogadzira tsinga itsva dzinokuvadza.

Funga nezve VEGF-165 semutungamiriri wekuvaka anopa mirairo yekuvaka tsinga dzeropa kwadisingadiwi. Pegaptanib inoita semutariri anopinda kuti amise mirairo iyoyo yekuvaka, achidzivirira kuumbwa kwetsinga dzeropa dzinobuda mvura, dzisina kujairika kuseri kwema retina ako.

Mushonga uyu unoonekwa seunoshanda zvine mwero kana uchienzaniswa nemishonga mitsva ye anti-VEGF. Nepo ichigona kunonotsa kurasikirwa kwekuona muvanhu vazhinji, inogona kunge isina simba semamwe marapirwo aripo nhasi. Nyanzvi yako yeziso ichafunga nezve mamiriro ako chaiwo uye nhoroondo yekurapa kana ichifunga kana pegaptanib iri sarudzo yakakunakira.

Mhedzisiro ye pegaptanib ndeyenguva pfupi, ndosaka uchida majekiseni enguva dzose. Mushonga unonyungudika zvishoma nezvishoma muziso rako kwemavhiki akati wandei, saka kuchengetedza kurapwa nguva dzose kwakakosha kuchengetedzwa kwakabatana nekurasikirwa kwekuona.

Ndinofanira Kutora Sei Pegaptanib?

Pegaptanib inopiwa chete nachiremba wemaziso ako kuburikidza nejekiseni rakananga muziso rako. Hauzive mushonga uyu kumba, uye unoda nzvimbo yekiriniki yakachena kuti uve nechokwadi chekuchengeteka kwako.

Usati wapiwa jekiseni, chiremba wako achachenesa nzvimbo yakatenderedza ziso rako uye anogona kukupa madonhwe ekunyaradza kuti aderedze kusagadzikana. Jekiseni chairo rinotora masekondi mashoma, kunyangwe kugadzwa kwese kungatora maminitsi makumi matatu kusvika makumi matanhatu kusanganisira kugadzirira uye kuongorora mushure.

Haufaniri kutsanya kana kudzivisa chikafu usati wagadzwa, asi unofanirwa kuronga kuti mumwe munhu akutyairire kumba mushure. Kuona kwako kunogona kuva kwakajeka kwenguva pfupi, uye unogona kuva nekunzwa chiedza kwemaawa mashoma mushure mejekiseni.

Mushure mejekiseni, chiremba wako anogona kukurudzira kushandisa madonhwe eantibiotic emaziso kwemazuva akati wandei kudzivirira hutachiona. Iwe unofanirwawo kudzivisa kukwiza maziso ako uye kuachengeta akachena uye akaoma kwezuva rekutanga kana maviri.

Ndingatora Pegaptanib Kwenguva Yakareba Sei?

Kurapa kwePegaptanib kunowanzo sanganisira majekiseni nguva dzose mumasvondo matanhatu ega ega, uye iwe ungangoda kurapwa kwenguva refu sezvo uine wet AMD inoshanda. Ichi chimiro chisingaperi chinoda manejimendi anoenderera mberi kuti achengetedze mabhenefiti ekurapa.

Chiremba wemaziso ako achatarisa mhinduro yako yekurapa kuburikidza nekuongororwa kwemaziso nguva dzose uye bvunzo dzekufungidzira. Vamwe vanhu vanogona kuona kugadzikana kwekuona kwavo mukati memwedzi mishoma yekutanga, nepo vamwe vangada kurapwa kwakawanda vasati vaona kuvandudzwa.

Kureba kwekurapa kunosiyana zvakanyanya kubva kumunhu nemunhu. Vamwe vanhu vangada majekiseni epegaptanib kwemakore, nepo vamwe vachigona kuchinjira kune dzimwe nzira dzekurapa kana kuona kufambira mberi kwechirwere kunochinja chirongwa chavo chekurapa.

Zvakakosha kuti usamira kurapwa kamwe kamwe, kunyange kana maonero ako achiita seakagadzikana. Mamiriro ezvinhu ari pasi ayo anokonzera kukura kwemidzi yeropa isina kujairika achiripo, uye kumisa kurapwa kungaita kuti uone kurasikirwa nekukurumidza.

Ndezvipi Zvakaipa zvePegaptanib?

Vanhu vazhinji vanotsungirira pegaptanib zvakanaka, asi semushonga chero upi zvake, unogona kukonzera mhedzisiro. Izvo zvakajairika zvine chekuita nekuita jekiseni pachayo pane mushonga.

Heano mhedzisiro yakajairika yaungasangana nayo:

• Kurwadziwa kweziso kana kusagadzikana kwezuva rimwe kana maviri mushure mejekiseni
• Maonero akajeka kwenguva pfupi kana kusagadzikana kwekuona
• Kunzwa sekunge une chimwe chinhu muziso rako
• Kuwedzera kuburitswa kwemvura yeziso
• Kutsvedza kudiki kana kutsamwa kutenderedza nzvimbo yejekiseni
• Madiki madiki anoyangarara mumaonero ako (floaters)
• Kunzwa chiedza kwemaawa mashoma mushure mekurapa

Izvi zvinowanzoitika zvinowanzoenda mukati memazuva mashoma uye kazhinji hazvikonzeri kunetseka. Zvisinei, unofanira kubata chiremba wako kana vakaenderera mberi kana kuipa.

Kune zvakare zvimwe zvakakomba asi zvisingawanzoitiki mhedzisiro iyo inoda kutariswa kwekurapa nekukurumidza. Kunyange zvazvo matambudziko aya asingawanzoitiki, zvakakosha kuti uzive nezvavo:

• Kutapukirwa kweziso kwakanyanya (endophthalmitis)
• Kuwedzera kukuru kwekumanikidzwa kweziso
• Retinal detachment
• Kurasikirwa kwakanyanya kwekuona
• Kurwadziwa kweziso kwakanyanya
• Kutanga kamwe kamwe kwemafloaters matsva akawanda
• Mwenje unopenya kana kurasikirwa kwekuona kwakaita semucheka

Kana iwe ukasangana nechero eaya akakomba zviratidzo, kunyanya mukati memazuva mashoma ekutanga mushure mejekiseni, bata chiremba wako wemaziso nekukurumidza kana kutsvaga rubatsiro rwekurapa rwechimbichimbi.

Ndiani Asingafaniri Kutora Pegaptanib?

Pegaptanib haina kukodzera munhu wese, uye chiremba wako achanyatsoongorora kana zvakachengeteka kwauri. Vanhu vane mamwe mamiriro ezvinhu eziso kana zvirwere havafaniri kugamuchira kurapwa uku.

Hamufaniri kugamuchira pegaptanib kana muine hutachiona hwemaziso hunoshanda kana kuzvimba mumaziso enyu kana pedyo nemaziso enyu. Izvi zvinosanganisira mamiriro akaita se conjunctivitis, uveitis, kana chero hutachiona hwebhakitiriya, hutachiona hwehutachiona, kana hutachiona hwefungal husingabatwi zvakanaka.

Vanhu vane allergy inozivikanwa ku pegaptanib kana chero chimwe chezvinhu zvayo vanofanira kudzivisa mushonga uyu. Kana makambove nemaitiro ekuita allergy kune mamwe mishonga ye anti-VEGF, ita shuwa kuti munokurukura izvi nachiremba wenyu musati matanga kurapwa.

Mamwe mamiriro ezvinhu emaziso anogona kuita kuti pegaptanib isakodzere kana kuda matanho chaiwo. Chiremba wenyu achada kuongorora kana muine glaucoma yakakomba, kuvhiyiwa kwemaziso kuchangobva kuitwa, kana mamwe matambudziko e retinal anogona kuwedzera njodzi yenyu yematambudziko.

Kana muri nepamuviri kana muchiyamwisa, kurukurai njodzi nemabhenefiti nachiremba wenyu. Kunyange zvazvo paine mashoko mashoma pamusoro pemigumisiro ye pegaptanib panguva yekuzvitakura, chiremba wenyu achayera mabhenefiti anogona kuitika achipesana nenjodzi dzinogona kuitika kwamuri nemwana wenyu.

Mazita eBrand ePegaptanib

Pegaptanib inotengeswa pasi pezita rebrand Macugen munyika zhinji kwaanowanikwa. Iri ndiro zita rekutanga rekutengesa rauchaona pamishonga uye magwaro ekurapa.

Dzimwe nyika dzinogona kuva nemazita akasiyana ebrand kana shanduro dzakajairika dziripo, asi Macugen inoramba iri zita rebrand rinonyanya kuzivikanwa re pegaptanib. Chiremba wenyu kana pharmacist vanogona kusimbisa zita chairo rebrand rinoshandiswa munzvimbo yenyu.

Paunenge uchikurukura kurapwa kwenyu nevapi vehutano, unogona kureva mushonga wako se pegaptanib kana Macugen, uye vachanzwisisa kuti muri kutaura nezvemushonga mumwe chete.

Zvimwe Zvingashandiswa Panzvimbo pePegaptanib

Mishonga yakati wandei ye anti-VEGF iripo yekurapa wet AMD, uye vazhinji vava kushandiswa kazhinji kupfuura pegaptanib. Chiremba wenyu angangofunga izvi zvimwe zvimwe zvichibva pazvido zvako zvakananga uye mhinduro yekurapa.

Ranibizumab (Lucentis) mushonga mutsva we anti-VEGF uyo unowanzo shanda zvakanyanya kupfuura pegaptanib. Inovharira mhando dzakawanda dzeVEGF panzvimbo imwe chete, zvichigona kupa mhedzisiro iri nani kune varwere vazhinji.

Bevacizumab (Avastin) imwe sarudzo iyo dzimwe nguva inoshandiswa kunze kwemavara ekurapa AMD. Kunyangwe isina kubvumidzwa zvakananga kune mamiriro eziso, vanachiremba vazhinji vanoi shandisa nekuti inoshanda uye inodhura zvakanyanya kupfuura dzimwe sarudzo.

Aflibercept (Eylea) mushonga mutsva uyo unovharira zvese VEGF uye imwe protein inonzi PlGF. Inowanzo kuda majekiseni mashoma kupfuura mamwe marapirwo, izvo zvinogona kuve zviri nyore kune varwere.

Chiremba wako weziso achafunga nezvezvinhu zvakaita sekuoma kwechirwere chako, nhoroondo yekurapa, inishuwarenzi, uye zvaunofarira pachako paunenge uchikurudzira iyo yakanakisa sarudzo yekurapa iwe.

Ko Pegaptanib Ari Nani Kupfuura Ranibizumab?

Ranibizumab (Lucentis) inowanzoonekwa seinoshanda zvakanyanya kupfuura pegaptanib pakurapa wet AMD. Zvidzidzo zvekiriniki zvakaratidza kuti ranibizumab inowanzo kupa mhedzisiro yekuona iri nani uye inogona kuvandudza kuona panzvimbo yekungononotsa kurasikirwa kwekuona.

Musiyano mukuru ndewekuti ranibizumab inovharira ese mafomu eVEGF, nepo pegaptanib ichivharira imwe chete mhando (VEGF-165). Iyi blockade yakakura inowanzo shandura kune mhedzisiro yekurapa iri nani kune varwere vazhinji.

Zvisinei, pegaptanib inogona kunge ichiri yakakodzera kune vamwe vanhu, kunyanya avo vasina kupindura zvakanaka kune mamwe marapirwo kana vane mamiriro ezvinhu chaiwo emishonga anoita kuti dzimwe sarudzo dzisanyanya kukodzera. Chiremba wako achafunga nezve mamiriro ako ega paunenge uchisarudza pakati pemishonga iyi.

Mishonga yese ine maprofiles akafanana ekuchengetedza, saka sarudzo inowanzo kuuya pasi pekushanda uye nyore nyore zvinhu zvakaita sejekiseni frequency uye mutengo wekufunga.

Mibvunzo Inowanzo Bvunzwa Nezve Pegaptanib

Ko Pegaptanib Yakachengeteka Kune Varwere vane Chirwere cheShuga?

Hongu, pegaptanib inowanzova yakachengeteka kune vanhu vane chirwere cheshuga, asi chiremba wako achada kukutarisa zvakanyanya. Chirwere cheshuga chinogona kukanganisa tsinga dzeropa mumuviri wako wese, kusanganisira idzo dziri mumaziso ako, saka chiremba wako wemaziso achada kuona chero shanduko mune yako diabetic retinopathy.

Kana uine diabetic macular edema pamwe chete neAMD, chiremba wako angangoda kugadzirisa chirongwa chako chekurapa. Dzimwe nguva vanhu vane chirwere cheshuga vanoda mishonga yakasiyana kana kurapwa kwakasiyana-siyana kuti vatarise zvese zvirwere zvacho nemazvo.

Ndoitei Kana Ndikakanganwa Kudya Pegaptanib?

Kana ukakanganwa jekiseni rako re pegaptanib rakarongeka, taura nehofisi yachiremba wako wemaziso nekukurumidza sezvinobvira kuti urongezve. Usamirira kusvika nguva yako inotevera yenguva dzose, sezvo kusavapo kwekurapa kunogona kubvumira mamiriro ako kuti aipisise.

Chiremba wako anogona kuda kukuona mukati mevhiki kana maviri kubva kumusangano wako wakakanganwa kuti aongorore mamiriro ako eziso uye aone nguva yakanakisa yejekiseni rako rinotevera. Kukanganwa jekiseni rimwe chete kazhinji hakuzokonzere kukuvadza zvachose, asi kurapwa nguva dzose kwakakosha kuchengetedza chiono chako.

Ndoitei Kana Ndikawana Zvakaipa Zvikuru Zvinokonzerwa?

Kana ukaona kurwadziwa kwakanyanya kwemaziso, kurasikirwa kwechiono kamwe kamwe, kana zviratidzo zvehutachiona mushure mejekiseni rako re pegaptanib, taura nechiremba wako wemaziso nekukurumidza kana kutsvaga rubatsiro rwekurapa rwechimbichimbi. Zviratidzo izvi zvinogona kuratidza matambudziko akakomba anoda kurapwa nekukurumidza.

Chengeta ruzivo rwechiremba wako rwekubata nekukurumidza rwuripo, uye usazeze kufona kana uchinetseka nezve chero zviratidzo. Zviri nani nguva dzose kungwarira kana zvasvika pakuona kwako uye hutano hwemaziso.

Ndingamira Rini Kutora Pegaptanib?

Unofanira kungomira kurapwa kwe pegaptanib pasi pekutungamirirwa nachiremba wako. Kunyangwe kana chiono chako chichiita sechakamira zvakanaka, mamiriro ari pasi ayo anokonzera kukura kwetsinga dzeropa zvisina kujairika achiripo, uye kumisa kurapwa kunogona kutungamira kurasikirwa kwechiono nekukurumidza.

Chiremba wako achagara achiongorora mamiriro ako kuburikidza nekutarisa maziso uye bvunzo dzekuona. Kana AMD yako ikava isingashande kana kana ukaona matambudziko anoita kuti kurapwa kuenderere mberi kusakodzera, vachakurukura kumisa kana kuchinja chirongwa chako chekurapa.

Ndingatyaira Mushure meKuwana Jekiseni rePegaptanib here?

Haufanire kutyaira pakarepo mushure mekuwana jekiseni repegaptanib. Madonhwe ekunyaradza uye jekiseni pacharo zvinogona kukanganisa kuona kwako kwenguva pfupi, zvichiita kuti zvisachengeteke kutyaira kwemaawa akati wandei mushure mezvo.

Ronga kuti mumwe munhu akutyairire kuenda nekubva kumusangano wako, kana kuronga imwe nzira yekufambisa. Vanhu vazhinji vanogona kutangazve mabasa avo enguva dzose, kusanganisira kutyaira, zuva mushure mejekiseni ravo kana chero mhedzisiro yenguva pfupi yekuona yapera.