Chii chinonzi Phenylephrine (Nzira yeIntravenous): Zvinoshandiswa, Dosage, Side Effects uye Zvimwe

Phenylephrine intravenous mushonga unokwidza ropa nekusimbisa tsinga dzeropa mumuviri wako wese. Inowanzo shandiswa munzvimbo dzekuchipatara kana ropa rako richidzika zvakanyanya panguva yekuvhiwa kana kurwara zvakanyanya. Mushonga uyu une simba unoshanda nekukurumidza kuburikidza nemitsipa yako kuti ubatsire kudzorera kuyerera kweropa kwakajairika kumitezo yakakosha semoyo wako, uropi, uye itsvo.

Chii chinonzi Phenylephrine (Nzira yeIntravenous)?

Phenylephrine intravenous mushonga we synthetic unotevedzera hormone yechisikigo inonzi norepinephrine mumuviri wako. Iyo ndeyeboka remishonga inonzi alpha-1 adrenergic agonists, zvinoreva kuti inoshandisa ma receptors akati wandei mutsinga dzako dzeropa. Kana ma receptors aya ashandiswa, anoita kuti tsandanyama yakatsetseka mumadziro etsinga dzako dzeropa isungane, ichiita kuti tsinga dziwedzere kuoma uye kuwedzera ropa.

Mushonga uyu wakasiyana zvakanyanya nephenylephrine inowanikwa mumishonga yekuzora mhino isingatengwi. Fomu ye intravenous yakasimba zvikuru uye inoshanda mumuviri wako wese wekutenderera. Yakagadzirirwa mamiriro ekukurumidzira uko kugadzirisa nekukurumidza kweropa kwakakosha kuti upone.

Vapi vehutano vanoona izvi sevasopressor ine simba, zvinoreva kuti yakagadzirirwa zvakananga kusimbisa tsinga dzeropa uye kukwidza ropa. Mhedzisiro yacho inowanzo kutanga mukati memaminitsi mashoma ekutarisirwa uye inogona kudzora nekuchenjerera nekugadzirisa chiyero chekudzora.

Chii chinonzi Phenylephrine (Nzira yeIntravenous) chinoshandiswa?

Phenylephrine intravenous inonyanya kushandiswa kurapa ropa rakaderera zvakanyanya (hypotension) rinoitika panguva yezvinhu zvekurapa kana kurwara zvakanyanya. Mamiriro akajairika ndeye panguva ye spinal kana epidural anesthesia, uko mushonga unovharira zviratidzo zvevhavha zvinowanzo kubatsira kuchengetedza ropa.

Panguva yekuvhiyiwa, ropa rako rinogona kudzikira nekuda kwezvinokonzerwa neanesthesia, kurasikirwa kweropa, kana shanduko mumuviri. Mushonga uyu unobatsira kuchengetedza kuyerera kweropa kwakakwana kumuviri wako apo zvikwata zvekurapa zvinogadzirisa chikonzero chacho. Zvinonyanya kubatsira panguva yekuvhiyiwa kwecesarean, uko kuchengetedza ropa remukadzi kwakakosha kumumweya nemwana.

Mushonga uyu unoshandiswawo mumayuniti ekuchengetedza zvakanyanya kune varwere vari kusangana nekuvhunduka. Mamiriro aya anoitika apo midzi yeropa inova yakakura zvisina kujairika nekuda kwezvirwere zvakakomba, maitiro ekurwara, kana dzimwe njodzi dzekurapa. Nekudzvinyirira midzi iyi, phenylephrine inobatsira kudzorera kutenderera kwakajairika.

Kazhinji, vanachiremba vanogona kushandisa mushonga uyu kurapa matambudziko emoyo kana kutsigira ropa panguva yekuongorora. Zvisinei, izvi zvinoshandiswa zvinowanzo chengeterwa mamiriro ezvinhu ekiriniki apo mamwe marapirwo haakodzeri.

Phenylephrine (Nzira yeIntravenous) Inoshanda Sei?

Phenylephrine inoshanda nekubatanidza kune alpha-1 adrenergic receptors iri mumhasuru dzakatsetseka dzemadziro emidzi yeropa. Funga nezve receptors izvi sezvinhu zvinodzora kuti midzi yeropa yako yakasimba sei kana yakasununguka. Kana phenylephrine ikashandisa zvinhu izvi, zvinokonzera kuti fiber dzemhasuru dzibatanidze, zvichiita kuti midzi ive yakamanana.

Iyi mhedzisiro yekumanikidza, inonzi vasoconstriction, inowedzera kuramba kunosangana neropa sezvo richiyerera mumuviri wako. Kana kuramba kuchikwira, ropa rako rinokwira, richiva nechokwadi chekuti kuyerera kweropa kwakakwana kunosvika kumuviri wakakosha. Mushonga unoshanda zvakanyanya pamitsipa uye arterioles, iyo iri midzi yeropa diki iyo ine simba guru pamaropa.

Mhedzisiro yacho inokurumidza, kazhinji inotanga mukati me1-2 maminitsi mushure mekuiswa mumutsipa. Izvi zvinoita kuti ive sarudzo yakanaka mumamiriro ezvinhu ekukurumidzira apo rutsigiro rweropa runodiwa nekukurumidza. Mhedzisiro yemushonga uyu inogarawo kwenguva pfupi, ichigara kwemaminitsi gumi nemashanu kusvika makumi maviri, izvo zvinobvumira vanachiremba kuti vagadzirise zvakarurama.

Kusiyana nemimwe mishonga yeropa, phenylephrine haina zvakanyanya pamwoyo kana simba remwoyo. Chiito ichi chinosarudza chinoita kuti chive chinobatsira kana chiremba achida kukwidza ropa pasina kukanganisa basa remwoyo.

Ndingatora sei Phenylephrine (Nzira yeIntravenous)?

Phenylephrine intravenous inongoiswa chete nevashandi vehutano vakadzidziswa muzvipatara kana mumakiriniki. Hauzotoreri mushonga uyu kumba, sezvo uchida kuongororwa nguva dzose uye kuyerwa kwakarurama kuburikidza nekuwana intravenous.

Mishonga iyi inowanzo kupiwa kuburikidza nemutsara weintravenous wakatsaurirwa, kazhinji mutsinga huru dzakaita sedzemaoko ako kana ruoko. Mumamiriro ezvinhu akakomba, inogona kupihwa kuburikidza necentral venous catheter, iyo ipaipi yakakosha inoiswa mutsinga huru padyo nemoyo wako. Izvi zvinovimbisa kuti mushonga unosvika muropa rako nekukurumidza uye zvinobudirira.

Vashandi vehutano vacharamba vachiongorora ropa rako, mwoyo, uye mazinga eokisijeni paunogamuchira mushonga uyu. Vachagadzirisa chiyero chekudzika zvichienderana nemhinduro yemuviri wako uye mamiriro chaiwo ekurapa. Chinangwa ndechekuchengetedza ropa rako mukati mehuwandu hwakachengeteka uchidzivirira kuwedzera kwakanyanya kungakonzera matambudziko.

Nzira yekupa mushonga inosanganisira kusanganisa mhinduro yakanyanya ye phenylephrine nemvura yakachena isati yaiswa mumuviri. Kusanganisa uku kunovimbisa kupa mushonga zvakachengeteka uye zvine chitsama. Chikwata chako chekurapa chichatarisawo panzvimbo yekuisa mushonga mumuviri kuti chione zviratidzo zvekutsamwa kana kupinda, izvo zvinoitika kana mushonga wabuda mumativi akapoteredza.

Ndingatora Phenylephrine (Nzira Yemumuviri) Kwenguva Yakareba Sei?

Kureba kwenguva yekurapa ne phenylephrine kunoenderana zvachose nemamiriro ako ezvinhu uye kuti muviri wako unopindura sei kumushonga. Muzviitiko zvakawanda, zvakadai semunguva yekuvhiyiwa, unogona kuiwana kwemaawa mashoma chete kusvikira chikonzero chekuderera kweropa chigadziriswa.

Pakuita kuvhiyiwa, mushonga unowanzo tangwa kana kudzvanywa kweropa kuchiderera uye uchienderera mberi kusvikira mhedzisiro yeanesthesia yapera kana maitiro ekuvhiya apera. Izvi zvinogona kubva pamaminitsi makumi matatu kusvika kumaawa akati wandei, zvichienderana nekuomarara kwekuvhiyiwa uye kupindura kwako kwega.

Mumamiriro ezvinhu ekutarisirwa zvakanyanya, nguva yekurapa inogona kusiyana zvakanyanya. Vamwe varwere vanogona kuda rubatsiro kwemazuva akati wandei apo mamiriro avo ari nani. Zvisinei, vanopa hutano vanowanzo chinangwa chekushandisa dosi yakaderera inoshanda kwenguva pfupi kudzivirira migumisiro inogona kuitika.

Chikwata chako chekurapa chichaderedza zvishoma nezvishoma mushonga panzvimbo yekumisa kamwe kamwe. Iyi nzira yekuderedza inobvumira muviri wako kuti ugadzirise uye inobatsira kudzivirira kudonha kweropa kamwe kamwe. Maitiro ekuregedza anowanzoitika kwemaawa akati wandei kusvika kumazuva, zvichienderana nemamiriro ako uye kugadzikana.

Ndezvipi Zvipingamupinyi zvePhenylephrine (Nzira Yemumuviri)?

Nepo phenylephrine ichiwanzotsungirirwa zvakanaka kana ichishandiswa zvakakodzera, inogona kukonzera mhedzisiro yakasiyana-siyana nekuda kwemhedzisiro yayo ine simba pamidzi yeropa. Kunzwisisa izvi zvinogona kuitika zvinogona kukubatsira kutaura chero zvaunonetseka nazvo nechikwata chako chekurapa.

Zvimwe zvinokonzeresa zvaungawana zvinowirirana nemishonga inoderedza tsinga dzeropa:

• Kutemwa nemusoro, kunoitika nekuti tsinga dzeropa mumusoro mako dzinoderedzwa kwenguva pfupi
• Kunzwisisa kufara kana kusagadzikana sezvo muviri wako uchigadzirisa kumishonga
• Kusvotwa kana kusagadzikana mudumbu, kunyanya kana kuyerera kweropa kumuviri wekugaya kuchikanganiswa
• Ganda rinotonhora kana rakachenuruka, kunyanya mumaoko ako netsoka, nekuda kwekuderera kweropa kumativi
• Kutadza kurara kana kunzwa jittery, kunyangwe izvi zvisingawanzoitiki nekushandiswa kweintravenous

Zviitiko izvi zvakajairika zvinowanzoenda nekukurumidza kana mushonga wamiswa kana chiyero chaderedzwa.

Zvimwe zvinokonzeresa zvakakomba zvinogona kuitika, kunyanya nemadosi akakwirira kana muvarwere vane mamwe mamiriro ezvinhu ekurapa:

• Kukwira kweropa kwakanyanya (hypertension) kunogona kutungamira kune sitiroko kana matambudziko emoyo
• Kurova kwemoyo kunonoka (bradycardia) sezvo muviri wako uchiedza kutsiva kuwedzera kweropa
• Kurwadziwa muchipfuva kana kutadza kufema kana ropa richikwira nekukurumidza
• Matambudziko eitsvo nekuda kwekuderera kweropa kuitsvo
• Kukuvadzwa kwetishu panzvimbo yekujekesa kana mushonga uchidonha mumativi akapoteredza

Zvisingawanzoitiki asi zvinogona kuva zvakakomba zvinosanganisira maitiro akakomba ekuita allergic, kunyangwe izvi zvisingawanzoitiki. Chikwata chako chehutano chinotarisa zviitiko izvi nguva dzose uye chinogona kugadzirisa nekukurumidza kurapwa kana matambudziko akamuka.

Ndiani Asingafaniri Kutora Phenylephrine (Intravenous Route)?

Mamiriro akati wandei ekurapa uye mamiriro anoda kungwarira kwakakosha kana anogona kudzivirira kushandiswa kwe phenylephrine intravenous. Chikwata chako chehutano chichanyatsoongorora nhoroondo yako yekurapa usati wapa kuti uve nechokwadi chekuchengeteka.

Haufanire kugamuchira phenylephrine kana uine mamwe mamiriro emoyo anogona kuwedzerwa nekukwira kweropa:

• Kutambudzika kukuru kwetsinga dzemoyo kana kurwisa kwemoyo kwemazuva ano, sezvo kuwedzera kweropa kunogona kukuvadza moyo wako
• Matambudziko akakomba emavharuvhu emoyo, kunyanya aortic stenosis, uko kuwedzera kweropa kunogona kuva nenjodzi
• Mamwe marwiro emoyo asina kujairika anogona kuwedzerwa nemishonga
• Kukwira kweropa kwakanyanya kwakaoma kudzora nemimwe mishonga

Zvimwe zvirwere zvinoda kungwarira zvakanyanya zvinosanganisira chirwere chakakomba chetsinga dzeropa, uko kumwe kutetepa kwetsinga dzeropa kunogona kukonzera kukuvadzwa kwetishu.

Kuzvitakura kunoda kufunga kwakakosha, kunyangwe phenylephrine dzimwe nguva inoshandiswa panguva yekuvhiyiwa kwemwana kana zvakanakira zvichipfuura njodzi. Chikwata chako chekubatsira pakuzvitakura chichanyatso funga nezvesarudzo zvichienderana nemamiriro ako chaiwo uye hutano hwemwana wako.

Varwere vane chirwere cheshuga, chirwere cheitsvo, kana matambudziko echiropa vangangoda kugadziridzwa kwemadosi kana kumwe kuongororwa. Izvi zvinogona kukanganisa nzira iyo muviri wako unogadzirisa mishonga uye zvinogona kuwedzera njodzi yematambudziko.

Mazita ePhenylephrine Brand

Phenylephrine intravenous inowanikwa pasi pemazita akati wandei emhando, kunyangwe zvipatara zvakawanda zvichishandisa mhando dzakajairika. Zita rinowanzozivikanwa ndere Neo-Synephrine, iro rakashandiswa munzvimbo dzekurapa kwemakumi emakore.

Mamwe mazita emhando anosanganisira Vazculep uye akasiyana-siyana mafomula akajairika ane chinhu chimwe chete chinoshanda. Zvisinei nemhando chaiyo, ese mavhezheni anoshanda nenzira imwechete uye ane maitiro akafanana kune ropa uye tsinga dzeropa.

Kukosheswa uye kurongwa kunogona kusiyana pakati pevagadziri, asi vanopa hutano vanodzidziswa kushandisa chero vhezheni yakatenderwa zvakachengeteka. Zvipatara zvakawanda zvine protocol yekuderedza uye kupa mishonga zvisinei nemhando chaiyo iripo.

Zvakakosha kuziva kuti phenylephrine inopiwa nemutsinga yakasiyana zvachose nemishonga inobvisa kuzvimba kwemumhino inowanikwa pasina chiremba inosanganisira chinhu chimwe chete chinoshanda. Mishonga inoshandiswa muchipatara yakanyanya kuwanda uye yakagadzirirwa kushanda mumuviri wese kwete kungobatsira kuzvimba kwemumhino.

Zvimwe Zvinogona Kushandiswa Panzvimbo pePhenylephrine

Mishonga yakati wandei inogona kushandiswa kurapa BP yakaderera, uye timu yako yezvehutano ichasarudza sarudzo yakakodzera zvichienderana nemamiriro ako chaiwo ehutano. Imwe neimwe sarudzo ine nzira dzakasiyana dzekushanda uye mhedzisiro.

Norepinephrine inowanzoonekwa semushonga wekutanga weBP yakaderera zvakanyanya muvarwere vanorwara zvakanyanya. Inoshanda pane ese alpha uye beta receptors, ichipa kuoma kwemidzi yeropa uku ichitsigirawo basa remoyo. Iyi chiito kaviri inoita kuti ive inobatsira zvakanyanya muvarwere vane matambudziko emoyo.

Epinephrine imwe imwe nzira ine simba inokanganisa mhando dzakawanda dze receptor. Inowanzo shandiswa mumamiriro ezvinhu ekukurumidzira senge allergic reactions yakanyanya kana kumira kwemoyo. Zvisinei, mhedzisiro yayo pamoyo rate uye rhythm inoita kuti isakodzere kune vamwe varwere.

Dopamine inogona kushandiswa pamadosi akakwirira kuwedzera BP, kunyangwe iine mhedzisiro yakaoma pamuviri wemuviri. Pamadosi akaderera, inonyanya kukanganisa basa reitsvo, nepo madosi akakwirira achipa kuoma kwemidzi yeropa yakafanana nephenylephrine.

Vasopressin inoshanda kuburikidza nemaitiro akasiyana zvachose nekukanganisa kuchengetwa kwemvura uye toni yemidzi yeropa. Dzimwe nguva inoshandiswa pamwe chete nemimwe mishonga kana kana kurapwa kwetsika kusiri kushanda.

Phenylephrine iri nani here pane Norepinephrine?

Sarudzo pakati pephenylephrine uye norepinephrine inoenderana nemamiriro ako chaiwo ehutano uye chikonzero cheBP yakaderera. Hapana mushonga wakanyanya

Phenylephrine inowanzofarirwa kana uchida kutsigira kumanikidzwa kweropa pasina kukanganisa zvakanyanya kumoyo kana kushanda kwemhasuru dzemoyo. Izvi zvinoita kuti zvive zvinobatsira zvakanyanya panguva ye spinal anesthesia, uko dambudziko rekutanga nderekuzaruka kwemidzi yeropa panzvimbo yekushanda kwemoyo.

Norepinephrine inowanzo sarudzwa kune varwere vanorwara zvakanyanya, kunyanya avo vane sepsis kana mamwe mamiriro anokanganisa akawanda masisitimu emuviri. Kugona kwayo kutsigira ese ari maviri midzi yeropa uye kushanda kwemoyo kunoita kuti ive yakawanda mumamiriro ezvinhu akaoma ekurapa.

Tsvagiridzo ichangoburwa inoratidza kuti norepinephrine inogona kunge iri nyore kune mamwe marudzi ekuvhunduka, kunyanya septic shock. Zvisinei, phenylephrine inoramba iri sarudzo inofarirwa yekudonha kweropa kunobatanidzwa neanesthesia uye mamiriro akasiyana ekushanda.

Chikwata chako chehutano chichafunga nezvezvinhu zvakaita sekushanda kwemoyo wako, hutano hwematsvo, uye chikonzero chaicho chekuderera kweropa kana uchisarudza pakati pemishonga iyi. Vanogonawo kuchinja pakati pemishonga yakasiyana zvichienderana nekuti muviri wako unopindura sei kurapwa.

Mibvunzo Inowanzo Bvunzwa Nezve Phenylephrine (Nzira yeIntravenous)

Q1. Phenylephrine Yakachengeteka Here Kune Vakadzi Vane Pamuviri?

Phenylephrine inogona kushandiswa panguva yekuzvitakura kana mabhenefiti achipfuura njodzi, kunyanya panguva ye cesarean sections. Mushonga unoyambuka placenta, asi zvidzidzo zvinoratidza kuti kazhinji yakachengeteka kupfuura kubvumira kuderera kwakanyanya kweropa kuti rienderere mberi panguva yekuzvara.

Chikwata chako cheobstetric chichanyatso tarisa kumanikidzwa kweropa rako uye kumhanya kwemoyo wemwana wako panguva yekutarisira. Vachashandisa yakaderera dose inoshanda uye vanogona kusarudza mamwe mishonga kana pamuviri wako uine matambudziko chaiwo anowedzera njodzi.

Q2. Ndingaita Sei Kana Ndikawana Phenylephrine yakawandisa netsaona?

Kana ukagamuchira phenylephrine yakawanda, chikwata chako chehutano chichaziva zviratidzo nekukurumidza kuburikidza nekutarisa nguva dzose. Zviratidzo zvekuwedzera dose zvinosanganisira high blood pressure yakanyanya, kurova kwemoyo kunononoka, uye shanduko dzinogona kuva nenjodzi mukushanda kwenhengo.

Kurapa kwekuwedzera dose kunosanganisira kumisa mushonga nekukurumidza uye kupa rutsigiro. Chikwata chako chekurapa chinogona kupa mishonga yekurwisa mhedzisiro uye chichatarisa zviratidzo zvako zvakakosha zvakanyanya kusvikira mhedzisiro yemushonga yapera, iyo inowanzoitika mukati memaminitsi gumi nemashanu-20.

Q3. Ndingaita Sei Kana Ndikakanganwa Dose yePhenylephrine?

Sezvo phenylephrine intravenous ichipihwa nguva dzose nevashandi vehutano, hapana kunetseka pamusoro pekukanganwa madose mupfungwa dzechinyakare. Mushonga unopihwa se infusion inogara iripo, uye chikwata chako chekurapa chinotarisa uye chinogadzirisa chiyero sezvinodiwa.

Kana infusion ikavhiringidzwa netsaona, vanopa hutano vako vachaitangazve nekukurumidza uye vachatarisa blood pressure yako zvakanyanya. Vanogona kuda kugadzirisa dose zvichienderana nekuti muviri wako unopindura sei kukuvhiringidzwa kwenguva pfupi.

Q4. Ndingamisa Rini Kutora Phenylephrine?

Sarudzo yekumisa phenylephrine inoenderana nemamiriro ako ezvinhu ekurapa uye kuti blood pressure yako inova sei yakagadzikana. Chikwata chako chehutano chichaderedza zvishoma nezvishoma dose pane kuimisa kamwechete kudzivirira kudonha kwemoyo kunongoerekana kwaitika.

Kune varwere vekuvhiyiwa, mushonga unowanzo miswa kana mhedzisiro yeanesthesia yapera uye blood pressure yako inogadzirika pachayo. Mumamiriro ezvinhu ekuchengetedzwa kwakanyanya, weaning inogona kutora mazuva akati wandei sezvo mamiriro ako ezvinhu achivandudza.

Q5. Phenylephrine Inogona Kukonzera Mhedzisiro Yenguva Refu Here?

Kana ichishandiswa zvakanaka kwenguva pfupi, phenylephrine haiwanzo kukonzera matambudziko enguva refu. Zvazvinoita mushonga wacho zvinongogara kwenguva pfupi uye zvinowanzoenda zvachose kana kurapwa kwapera. Zvisinei, kushandisa kwenguva yakareba pamadosi akakwirira kungakanganisa kushanda kweitsvo kana kukonzera kukuvara kwematishu.

Vashandi vehutano vako vanotarisa zviratidzo zvematambudziko panguva yekurapwa uye vanochinja kurapwa kuti vaderedze njodzi. Vanhu vazhinji havawani matambudziko anogara kubva mukurapwa kwe phenylephrine kana ichishandiswa pasi pekutariswa kwechiremba kwakakodzera.