Chii chinonzi Pimecrolimus: Zvazvinoshandiswa, Madosi, Migumisiro Yakaipa uye Zvimwe

Pimecrolimus mushonga we topical immunomodulator unobatsira kudzora eczema uye atopic dermatitis nekudzikamisa mhinduro yemasoja emuviri wako. Kusiyana nemakrimu e steroid, mushonga uyu unotorwa nemishonga unoshanda nekudzivisa maseru chaiwo emuviri anokonzera kuzvimba, zvichiita kuti ive sarudzo yakapfava asi inoshanda pakurapa mamiriro eganda anonzwa.

Kirimu iyi ndeyeboka remishonga inonzi calcineurin inhibitors, zvinoreva kuti inotarisa chikonzero che eczema flare-ups pasina migumisiro yenguva refu ine chekuita nekushandiswa kwenguva refu kwe steroid. Vanhu vazhinji vanoiwana ichibatsira zvikuru pakurapa nzvimbo dzakapfava dzakadai sechiso nemutsipa uko makrimu e steroid angave akaomarara.

Chii chinonzi Pimecrolimus chinoshandiswa?

Pimecrolimus inorapa mild kusvika pakati nepakati atopic dermatitis (eczema) muvanhu vakuru nevana vane makore anopfuura 2. Chiremba wako anonyora mushonga uyu kana dzimwe nzira dzekurapa dzisina kushanda zvakanaka kana paunoda sarudzo yakachengeteka yenguva refu yekugadzirisa eczema isingaperi.

Mushonga uyu unoshanda zvakanyanya kune eczema pachiso chako, mutsipa, nedzimwe nzvimbo dzinonzwa uko ganda rako rakakora. Inobatsira kuderedza matsvuku, anokwenya, akazvimba mapatches anoita kuti eczema isagadzikane uye inokanganisa hupenyu hwezuva nezuva.

Vamwe vanachiremba vanonyorawo pimecrolimus off-label kune mamwe mamiriro eganda anozvimba seborrheic dermatitis kana vitiligo, kunyangwe izvi zvinoshandiswa zvisina kubvumidzwa zviri pamutemo neFDA. Mupi wako wehutano achasarudza kana mushonga uyu wakakodzera mamiriro ako eganda.

Pimecrolimus inoshanda sei?

Pimecrolimus inoshanda nekudzivisa T-maseru uye mast cells muganda rako kubva pakuburitsa makemikari anozvimba anokonzera zviratidzo zve eczema. Funga nezvazvo sekumisa bhureki rakanyoro pamusoro pemhinduro yemasoja emuviri wako kune zvinokonzeresa izvo zvingasavhiringidza ganda rine hutano.

Mushonga uyu unoonekwa semushonga une simba repakati nepakati uyo une hunyoro kupfuura ma steroid mazhinji ekuzora. Hauchenese ganda rako sezvinogona kuitwa nema steroid, zvichiita kuti rive rakachengeteka kushandiswa kwenguva refu panzvimbo dzine hunyoro senge kumeso kwako uye kutenderedza maziso ako.

Iwe unowanzoona kuvandudzwa mukati memazuva mashoma kusvika vhiki yekushandisa nguva dzose, kunyangwe zvingatora mavhiki akati wandei kuti uone mabhenefiti akazara. Mushonga uyu unoenderera mberi uchishanda kunyangwe zviratidzo zvako zvichivandudzwa, zvichibatsira kudzivirira kupararira kutsva kana uchishandiswa sezvakarairwa.

Ndingatora sei Pimecrolimus?

Zora rukoko rutete rwekirimu ye pimecrolimus panzvimbo dzakakanganiswa kaviri pazuva, mangwanani nemanheru. Haufaniri kuikwiza zvakasimba - ingoitsvedzesa zvinyoro nyoro paganda rako kusvikira yanyura.

Nguva dzose geza maoko ako zvakakwana usati wazora kirimu, kunze kwekunge uchirapa maoko ako. Zora mushonga chete panzvimbo dzine eczema, uchidzivisa ganda rine hutano kutenderedza zvikamu zvakakanganiswa.

Unogona kuzora pimecrolimus paganda rakachena, rakaoma chero nguva yezuva, uine kana pasina chikafu sezvo iri mushonga wekuzora. Zvisinei, vanhu vazhinji vanoona zvichibatsira kuizora mushure mekugeza apo ganda ravo richiri kunyorova zvishoma kubatsira kuvhara hunyoro.

Usafukidze nzvimbo dzakabatwa nemabhandeji kana kupfeka kunodzivirira kunze kwekunge chiremba wako akakuudza zvakananga. Mushonga uyu unoshanda zvakanyanya kana ganda rako richikwanisa kufema zvakasikwa.

Ndingatora Pimecrolimus kwenguva yakareba sei?

Unofanira kushandisa pimecrolimus kwenguva yakareba sezvinokurudzirwa nachiremba wako, izvo zvinowanzoitika kusvikira zviratidzo zvako zve eczema zvanyangarika zvachose. Vanhu vazhinji vanoona kuvandudzwa kukuru mukati me2-6 mavhiki ekushandisa nguva dzose.

Kusiyana nema steroid ekuzora, pimecrolimus inogona kushandiswa zvakachengeteka kwenguva yakareba pasina kukonzera kuonda kweganda kana mamwe mativi enguva refu. Vamwe vanhu vanoiita nguva nenguva kwemwedzi kana kunyange makore kudzivirira eczema flare-ups.

Chiremba wenyu angakurudzira kumisa mushonga kana ganda renyu rachena uye wozotangazve kana zviratidzo zvichidzoka. Nzira iyi inokubatsira kushandisa mushonga mudiki unodiwa kuti eczema yenyu irambe ichidzorwa.

Ndezvipi Zvakaipa ZvePimecrolimus?

Vanhu vazhinji vanotsungirira pimecrolimus zvakanaka, asi semushonga upi zvawo, unogona kukonzera mhedzisiro. Mashoko akanaka ndeokuti mhedzisiro yakakomba haisi kazhinji, uye mhinduro zhinji dzakapfava uye dzenguva pfupi.

Heano mhedzisiro yakajairika yaungasangana nayo paunotanga mushonga uyu:

• Kunanzva kana kunzwa kunopfungaira panzvimbo yekushandisa (kazhinji kunovandudzika mukati memazuva mashoma)
• Kutsvuka kweganda kana kutsamwa
• Kukwenya kunogona kuwedzera kwenguva pfupi kusati kwavandudzika
• Kudziya kweganda kana kunzwa kunopfungaira
• Kurwadziwa nemusoro
• Zviratidzo zvakaita sefuruu

Mhinduro idzi dzakajairika dzinowanzo nyangarika ganda rako richigadzirisa kumushonga. Kana dzikaramba kana kuwedzera mushure mevhiki, taura nemupi wezvehutano wako kuti uwane gwara.

Mhedzisiro isingawanzoitiki asi yakakomba inoda kutariswa kwekurapa nekukasira uye inosanganisira:

• Zviratidzo zveutachiona hweganda (kuwedzera kutsvuka, kudziya, pus, kana mitsetse mitsvuku)
• Mhinduro dzakakomba dzekurwara (rash, kuzvimba, kuoma kufema)
• Kukura kweganda kusinganzwisisiki kana shanduko mumoles iripo
• Fivha inoramba iripo kana lymph nodes yakazvimba

Kunyange zvazvo zvisingawanzoitiki, kwave nekushuma kwekenza yeganda uye lymphoma muvanhu vachishandisa calcineurin inhibitors, kunyange zvazvo hukama hwakananga husina kuratidzwa. Chiremba wako anoyera njodzi idzi diki pamusoro pezvakanakira paanonyora mushonga uyu.

Ndiani Asingafaniri Kutora Pimecrolimus?

Pimecrolimus haisi yemunhu wese, uye mamiriro akati wandei anoita kuti isashandiswe. Chiremba wako achaongorora nhoroondo yako yekurapa zvakanyatsonaka asati anyora mushonga uyu.

Haufaniri kushandisa pimecrolimus kana uine chero mamiriro aya:

• Kuziva kusawirirana nemishonga ye pimecrolimus kana zvimwe zvinosanganiswa mumushonga uyu
• Zvirwere zviri kushanda paganda (zve mabhakitiriya, mavairasi, kana fungal)
• Muviri usina simba nekuda kwechirwere kana mishonga
• Kenza yeganda kana maronda asati ave kenza munzvimbo iri kurapwa
• Netherton's syndrome (chirwere chisingawanzoitiki cheganda chinokonzerwa nemajini)

Kungwarira kwakakosha kana uri nepamuviri, uchiyamwisa, kana kuronga kuva nepamuviri. Kunyange zvazvo zvidzidzo zvisina kuratidza mhedzisiro inokuvadza, chiremba wako achayerera mabhenefiti achienzanisa nenjodzi dzinogona kuitika kwauri nemwana wako.

Vana vari pasi pemakore maviri havafaniri kushandisa pimecrolimus, sezvo kuchengeteka nekushanda kwavo zvisina kusimbiswa kuboka rezera iri. Uye zvakare, vanhu vane zvimwe zvirwere zve autoimmune vangangoda kuongororwa zvakanyanya vachishandisa mushonga uyu.

Mazita eBrand e Pimecrolimus

Pimecrolimus inowanikwa pasi pezita rebrand Elidel munyika zhinji, kusanganisira United States. Iri ndiro zita rekutanga rebrand iro mushonga uyu wakatanga kubvumidzwa nekutengeswa.

Dzimwe nyika dzinogona kunge dzine shanduro dzakajairika, asi chinhu chinoshanda chinoramba chakafanana zvisinei nemugadziri. Mushonga wako unowanzo kupa shanduro inodhura zvakanyanya chirongwa chako cheinishuwarenzi.

Nguva dzose tarisa nemushonga wako kana ukaona misiyano muchitarisiko kana kurongwa kwemushonga wako, sezvo vachigona kusimbisa kuti uri kuwana fomu chaiyo.

Zvimwe Zvingashandiswa Panzvimbo pe Pimecrolimus

Kana pimecrolimus isingashande zvakanaka kwauri kana kukonzera mhedzisiro inonetsa, dzimwe nzira dzinogona kubatsira kubata eczema yako nemazvo. Chiremba wako anogona kukubatsira kuongorora sarudzo idzi zvichibva pazvido zvako zvakananga.

Zvimwe zvinodzivirira calcineurin zvinosanganisira tacrolimus (Protopic), iyo inoshanda zvakafanana asi inogona kuve yakasimba kune eczema yakaoma. Topical steroids dzemhando dzakasiyana dzinoramba dziri kurapwa kunowanzoitwa eczema, kunyangwe dzisina kukodzera kushandiswa kwenguva refu munzvimbo dzine hanya.

Zvimwe zvingasarudzwa zvitsva zvinosanganisira topical JAK inhibitors senge ruxolitinib (Opzelura) ye mild kusvika pakati nepakati eczema, uye crisaborole (Eucrisa), PDE4 inhibitor iyo inonyanya kunaka kuvana. Kune zviitiko zvakakomba, chiremba wako angangofunga nezve mishonga yemuromo kana biologics senge dupilumab (Dupixent).

Zvimwe zvingasarudzwa zvisiri zvekurapa zvinosanganisira ceramide-rich moisturizers, colloidal oatmeal preparations, uye zvinochenesa zvinyoro zvakagadzirirwa ganda rine hanya. Izvi zvinogona kushandiswa pamwe chete nekurapa kwekurapa kutsigira kupora kweganda rako.

Pimecrolimus Zviri Nani Kudarika Tacrolimus Here?

Zvese pimecrolimus uye tacrolimus zvinodzivirira calcineurin zvinoshanda zvakafanana, asi zvine misiyano yakakosha inoita kuti imwe neimwe ive yakakodzera mamiriro akasiyana. Hapana kana imwe yacho iri yese

Hongu, pimecrolimus yakachengeteka kuvana vane makore anopfuura 2 kana ichishandiswa sezvakarairwa nachiremba wevana. Mushonga uyu wakadzidzwa zvakanyanya kuvana uye kazhinji unofarirwa pane topical steroids yevana vadiki nekuti haitete ganda kana kukanganisa kukura.

Vana vanogona kunge vachinzwa zvakanyanya kunzwa kupisa kwekutanga, saka zvakakosha kuvagadzirira kusagadzikana uku kwenguva pfupi. Kutanga nezvinhu zvidiki uye zvishoma nezvishoma kuwedzera nzvimbo yekushandisa kunogona kubatsira kuderedza kutsamwa kwekutanga.

Ndoita Sei Kana Ndikashandisa Pimecrolimus Yakawandisa Netsaona?

Kana netsaona ukashandisa pimecrolimus yakawandisa, usavhunduka - mushonga uyu haunzwisisi nyore nyore muropa rako mumari ine njodzi. Ingo pukuta kirimu yakawandisa nejira rakachena, rakanyorova uye uenderere mberi nehurongwa hwako hwekushandisa nguva dzose.

Kushandisa zvakawanda kupfuura zvakarairwa hakuzobatsiri eczema yako kupora nekukurumidza uye kunogona kuwedzera njodzi yemigumisiro yakaita sekupisa kana kutsamwa. Kana iwe ukaona kupisa kwakanyanya, kutsvuka, kana zvimwe zviratidzo zvinonetsa mushure mekunyorera zvakawandisa, taura nemupi wako wehutano kuti uwane gwara.

Ndoita Sei Kana Ndikakanganwa Dose yePimecrolimus?

Kana iwe ukakanganwa dose, shandisa mushonga nekukurumidza paunorangarira, kunze kwekunge yave nguva yekushandisa yako inotevera yakarongwa. Muchiitiko ichocho, skip dose yakarasika uye uenderere mberi nehurongwa hwako hwenguva dzose.

Usashandisa mushonga wakawedzerwa kuti ugadzirise dose yakarasika, sezvo izvi zvinogona kuwedzera njodzi yemigumisiro. Kuenderana kwakakosha kupfuura nguva yakakwana, saka tarisa pakudzokera kune yako yenguva dzose.

Ndingamira Rini Kutora Pimecrolimus?

Iwe unogona kazhinji kumira kushandisa pimecrolimus kana zviratidzo zvako zveeczema zvanyatsojeka uye ganda rako radzoka kune zvakajairika. Izvi zvinowanzo tora 2-6 mavhiki ekushandisa nguva dzose, asi nguva inosiyana kune munhu mumwe nemumwe.

Usamira kamwe kamwe kana uchiri kuona kuvandudzika - ramba uchishandisa mushonga kusvika ganda rako ranyatsojeka. Chiremba wako anogona kukurudzira kuderedza zvishoma nezvishoma kushandiswa kwemushonga pane kumira kamwe kamwe kudzivirira kupararira.

Ndingashandisa Moisturizer nePimecrolimus here?

Hongu, unofanira kuramba uchishandisa moisturizer inononoka, isina hwema uchirapa eczema yako ne pimecrolimus. Moisturizing chikamu chakakosha chekugadzirisa eczema uye inobatsira mushonga kushanda zvakanyanya.

Shandisa moisturizer yako mushure mekunge pimecrolimus cream yapinda, kazhinji uchimirira maminitsi gumi nemashanu kusvika makumi matatu pakati pekushandisa. Iyi nzira yekumisikidza inobatsira kuvhara hunyoro uye inotsigira maitiro ekupora kweganda rako.