Chii chinonzi Plecanatide: Zvinoshandiswa, Mishonga, Migumisiro uye Zvimwe

Plecanatide mushonga unopiwa nachiremba unobatsira kurapa kuvharika kwenguva refu uye irritable bowel syndrome ine kuvharika (IBS-C). Kurapa uku kunonaka asi kunoshanda kunoshanda nekukurudzira matumbu ako kuti abudise mvura yakawanda, iyo inonyorovesa chigaro uye inoita kuti kufamba kwematumbu kuve nyore uye kugadzikana.

Chii chinonzi Plecanatide?

Plecanatide mushonga wepeptide we synthetic unotevedzera hormone yechisikigo mumuviri wako inonzi guanylin. Iyo ndeyeboka remishonga inonzi guanylate cyclase-C agonists, iyo inonzwika yakaoma asi inongoreva kuti inobatsira matumbu ako kushanda zvakanyanya.

Mushonga uyu unouya semupiritsi diki raunotora nemuromo kamwe chete pazuva. Kusiyana nemamwe ma laxatives akaomarara anogona kukonzera cramping kana kukurumidza, plecanatide inoshanda zvinyoro nyoro nemaitiro echisikigo emuviri wako kuti adzorere basa rakajairika rematumbu.

Iyo FDA yakabvumira plecanatide muna 2017 mushure mekunge zvidzidzo zvekiriniki zvakaratidza kuti zvinogona kuvandudza zvakanyanya kuwanda kwekufamba kwematumbu uye kuderedza kunetseka muvanhu vane kuvharika kwenguva refu.

Plecanatide Inoshandiswa Kunei?

Plecanatide inorapa mamiriro maviri makuru anokanganisa mamirioni evanhu pasi rese. Chiremba wako angakupa mushonga uyu kana uri kutambura nematambudziko ekugaya ayo anokanganisa hupenyu hwako hwezuva nezuva.

Kushandiswa kwekutanga ndeyekuvharika kwenguva refu idiopathic, zvinoreva kuvharika kwenguva refu pasina chikonzero chakajeka. Mamiriro aya anosanganisira kuve nekufamba kwematumbu kushoma katatu pavhiki, pamwe chete nezviratidzo zvakaita sekunetseka, zvigaro zvakaoma, kana kunzwa sekunge haugone kubvisa matumbu ako zvachose.

Plecanatide inorapawo irritable bowel syndrome ine kuvharika (IBS-C). Mamiriro aya anosanganisa zviratidzo zvekuvharika zvataurwa pamusoro apa pamwe chete nemarwadzo mudumbu, bloating, uye shanduko mumaitiro ematumbu ayo akagara kwemwedzi mitatu.

Plecanatide Inoshanda Sei?

Plecanatide inoshanda nekumutsa zvikwanisi zvakatarwa mumutsara wako wematumbu anonzi guanylate cyclase-C receptors. Kana izvi zvikwanisi zvamutswa, zvinotanga chiitiko chekuti chinowedzera mvura mumutsara wako wematumbu.

Mvura iyi yakawanda inobatsira kupfavisa chigaro chako uye inokurudzira kufamba kwemukati kwemuviri. Funga nezvazvo sekubatsira matumbu ako kuyeuka maitiro ekushanda zvakanaka pane kuvaedza kuti vashande zvisina kujairika.

Mishonga iyi inoonekwa seyakasimba zvishoma zvichienzaniswa nezvinhu zvinowanikwa pasina chiremba, zvakaita semafiber supplements, asi zvakapfava kupfuura mishonga yekurapa inokurudzira. Vanhu vazhinji vanoona kuvandudzwa mukati mevhiki yekutanga yekurapa, kunyangwe vamwe vachigona kuda kusvika mavhiki maviri kuti vawane zvizere zvinobatsira.

Kusiyana nemishonga yekurapa inokurudzira iyo inogona kurasikirwa nekushanda nekufamba kwenguva, plecanatide inochengetedza mabhenefiti ayo nekushandiswa kwakareba uye kazhinji haikonzeri kuvimba.

Ndingatora sei Plecanatide?

Tora plecanatide sezvinorayirwa nachiremba wako, kazhinji piritsi rimwe re3-mg kamwe pazuva. Unogona kuitora uine kana usina chikafu, asi kuitora panguva imwe chete zuva rega rega kunobatsira kuchengetedza mazinga akagadzikana mumuviri wako.

Medza piritsi rose negirazi remvura izere. Usapwanya, kutsenga, kana kuputsa piritsi, sezvo izvi zvinogona kukanganisa mashandiro emushonga mumuviri wako.

Kana uine dambudziko rekumedza mapiritsi, unogona kupwanya piritsi uye kusanganisa nechidiki cheapplesauce kana mvura. Shandisa musanganiswa uyu nekukasira uye usauchengete gare gare.

Gara wakanyatsodiridzwa zuva rese paunenge uchitora plecanatide. Kunwa mvura yakawanda kunobatsira mushonga kushanda zvakanyanya uye kunoderedza njodzi yemigumisiro.

Ndingatora Plecanatide kwenguva yakareba sei?

Kureba kwekurapa kwe plecanatide kunosiyana zvichienderana nemamiriro ako ega uye mhinduro kumushonga. Vanhu vazhinji vane constipations yechronic vanoda kurapwa kwenguva refu kuti vachengetedze basa renguva dzose remukati.

Chiremba wako anogona kukutanga pane bvunzo yemavhiki akati wandei kuti aongorore kuti mushonga unoshanda sei kwauri. Kana ukaona kuvandudzika kukuru muzviratidzo zvako, vanogona kukurudzira kuenderera mberi nekurapa.

Vamwe vanhu vane IBS-C vangada kurapwa nguva dzose kuti vakwanise kudzora mamiriro avo. Vamwe vangakwanisa kuderedza chiyero chavo kana kutora zororo kubva kumushonga kana zviratidzo zvavo zvavandudza.

Usambomira kutora plecanatide kamwechete usina kubvunza chiremba wako, sezvo zviratidzo zvako zvekuvhara zvinogona kudzoka. Mupi wako wehutano achakubatsira kuona chirongwa chakanakisa chekurapa kwenguva refu kune mamiriro ako chaiwo.

Ndezvipi Zvakaipa zvePlecanatide?

Semishonga yese, plecanatide inogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachizvitsungirira zvakanaka. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakavimbika nezvekurapa kwako.

Mhedzisiro yakajairika inowanzoita nyoro uye ine hukama nemaitiro emushonga. Heano mhedzisiro yaungasangana nayo:

• Manyoka (anoita nezve5% yevanhu)
• Kurwadziwa mudumbu kana kusagadzikana
• Flatulence (gasi)
• Kuzvimba mudumbu
• Nausea
• Musoro

Izvi zvinowanzoitika zvinowanzoita nani sezvo muviri wako uchigadzirisa kumushonga, kazhinji mukati memazuva mashoma ekutanga ekurapa.

Zvakanyanya asi zvisingawanzoitiki zvinoda kutariswa kwekurapa nekukasira. Kunyangwe zvisingawanzoitiki, unofanirwa kubata chiremba wako nekukasira kana ukaona:

• Manyoka akakomba kana anoramba asingavandudzi
• Zviratidzo zvekupera mvura mumuviri (dizziness, muromo wakaoma, kuderedzwa kwemvura)
• Kurwadziwa mudumbu kwakanyanya kwakasiyana nezviratidzo zvako zvenguva dzose
• Ropa mumagaro ako
• Nausea yakakomba kana kurutsa

Vanhu vazhinji vanowana kuti kutanga nekunyatsodiridza uye kutora mushonga nguva dzose kunobatsira kuderedza mhedzisiro.

Ndiani Asingafaniri Kutora Plecanatide?

Plecanatide haikodzeri kumunhu wese, uye mamiriro ezvinhu kana mamiriro ezvinhu echiremba anoita kuti isashandiswe. Chiremba wako achanyatsoongorora nhoroondo yako yezvokurapa asati akuraira mushonga uyu.

Haufanire kutora plecanatide kana uri pasi pemakore gumi nemasere, sezvo kuchengeteka nekushanda kwavo zvisina kumiswa muvana nevechiri kuyaruka. Mushonga uyu haukurudzirwiwo kana wakazvitakura kana kuyamwisa kunze kwekunge mabhenefiti achipfuura njodzi.

Mamiriro ezvinhu chaiwo ezvokurapa anoita kuti plecanatide isakodzere anosanganisira:

• Kuzivikanwa kwekuvharika kwematumbo kana kufungidzirwa kwekuvharika kwematumbo
• Kuvhiringidzika kwakanyanya kwematumbo (chirwere chaCrohn kana ulcerative colitis)
• Chirwere chakakomba cheitsvo
• Nhoroondo yerukosoro rukuru kana mamiriro erukosoro asingaperi
• Allergy kuplecanatide kana chero zvikamu zvayo

Udza chiremba wako nezvemamiriro ako ese ezvokurapa, kunyanya kana uine nhoroondo yematambudziko eitsvo, mamiriro ekuzvimba matumbo, kana uri kutora mamwe mishonga anogona kukanganisa plecanatide.

Mazita ePlecanatide Brand

Plecanatide inowanikwa pasi pezita remhando Trulance muUnited States. Iri ndiro zita remhando rimwe chete riripo, kunyangwe shanduro dzakajairika dzinogona kuwanikwa mune ramangwana.

Trulance inogadzirwa neBausch Health Companies uye inouya mumahwendefa e3-mg. Mushonga uyu unowanzo kufukidzwa nehurongwa hwakawanda hweinishuwarenzi, kunyangwe kufukidzwa kungasiyana zvichienderana nehurongwa hwako chaihwo uye kukosha kwekurapa.

Kana mutengo uchinetesa, bvunza chiremba wako nezve zvirongwa zvekubatsira varwere kana zvirongwa zvekuderedza pharmacy zvinogona kubatsira kuderedza mari yako yebasa.

Plecanatide Zvimwe Zvinhu

Mishonga yakati wandei inogona kurapa kuvharika kwematumbo kusingaperi uye IBS-C kana plecanatide isiri yako. Chiremba wako angangofunga nezveimwe nzira idzi zvichibva pazviratidzo zvako zvakatarwa uye nhoroondo yezvokurapa.

Mishonga mimwe yemishonga inopiwa nemishonga mumhando imwechete inosanganisira linaclotide (Linzess) uye lubiprostone (Amitiza). Izvi zvinoshanda kuburikidza nemaitiro akasiyana zvishoma asi zvine mhedzisiro yakafanana pabasa remudumbu.

Sarudzo dzisiri dzemishonga dzinogona kurudzirwa nachiremba wako dzinosanganisira:

• Polyethylene glycol (MiraLAX)
• Zvimwe zvepsyllium fiber
• Docusate sodium (Colace)
• Bisacodyl (Dulcolax)

Mupi wako wehutano achabatsira kuona kuti ndeipi sarudzo yekurapa yakakodzera mamiriro ako chaiwo uye zviratidzo.

Plecanatide Zviri Nani Kupfuura Linaclotide Here?

Zvese plecanatide uye linaclotide zvinobudirira kurapa kuvharika kusingaperi uye IBS-C, asi vane misiyano inogona kuita kuti imwe ive yakakodzera kwauri kupfuura imwe.

Plecanatide inogona kukonzera manyoka mashoma akaenzaniswa ne linaclotide, zvichiita kuti ive sarudzo iri nani kune vanhu vanonzwa kune iyi mhedzisiro. Zvidzidzo zvekiriniki zvinoratidza kuti plecanatide ine chiitiko chakaderera chekurapa-kuganhurira manyoka.

Linaclotide, kune rumwe rutivi, yanga iripo kwenguva refu uye ine data rakawanda rekiriniki rinotsigira kushandiswa kwayo. Inowanikwawo mumhando dzakawanda dzekushandisa, zvichibvumira sarudzo dzakawanda dzekushandisa.

Sarudzo pakati pemishonga iyi inowanzouya pasi pekupindura kwako wega, kushivirira kwemhedzisiro, uye kufunga kwemitengo. Chiremba wako achakubatsira kuona kuti ndeipi sarudzo yakakodzera mamiriro ako chaiwo.

Mibvunzo Inowanzo Bvunzwa Nezve Plecanatide

Plecanatide Yakachengeteka Kune Vanhu vane Chirwere cheshuga Here?

Hongu, plecanatide inowanzova yakachengeteka kune vanhu vane chirwere cheshuga. Mushonga haukanganisi mazinga eshuga yeropa zvakananga, uye zvidzidzo hazvina kuratidza chero kusangana kunofadza pakati pe plecanatide nemishonga yakajairika yechirwere cheshuga.

Asi, kana ukaona manyoka semhedzisiro, izvi zvinogona kukanganisa kutonga kweshuga yeropa rako kana kunyudzwa kwemishonga. Tarisa shuga yako yeropa zvakanyanya paunotanga plecanatide uye taura nachiremba wako kana ukaona chero shanduko dzisinganzwisisike.

Ndoita Sei Kana Ndakatora Plecanatide Yakawandisa Netsaona?

Kana netsaona ukatora plecanatide yakawanda kupfuura chiyero chawakanyorerwa, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira. Kutora yakawanda kunogona kuwedzera njodzi yako yemanyoka akakomba uye kupera mvura mumuviri.

Tarisa zviratidzo zvekupera mvura mumuviri zvakaita sedzungu, muromo wakaoma, kuderedzwa kwemvura, kana kunzwa uchitema. Inwa mvura yakawanda uye tsvaga rubatsiro rwekurapa kana ukaona manyoka akakomba kana anoramba achiitika.

Usaedze "kugadzirisa" chiyero chakawedzerwa nekusvetuka chiyero chako chinotevera chakarongeka. Dzokera kuchirongwa chako chekushandisa mishonga sezvakarairwa nachiremba wako.

Ndoita Sei Kana Ndikakanganwa Kutora Chiyero chePlecanatide?

Kana ukakanganwa kutora chiyero cheplecanatide, tora nekukasira paunorangarira, kunze kwekunge yava nguva yechiyero chako chinotevera chakarongeka. Muchiitiko ichocho, svetuka chiyero chawakakanganwa uye uenderere mberi nechirongwa chako chekushandisa mishonga.

Usatore zviyero zviviri panguva imwe chete kuti ugadzirise chiyero chawakakanganwa, sezvo izvi zvinogona kuwedzera njodzi yako yemhedzisiro. Kana iwe uchikanganwa zviyero kazhinji, funga kumisa chiyeuchidzo chezuva nezuva kana kutora mushonga panguva imwe chete zuva rega rega.

Kukanganwa zviyero dzimwe nguva hakuzokukuvadzi, asi edza kutora plecanatide nguva dzose kuti uwane mhedzisiro yakanaka mukutarisira zviratidzo zvako zvekuvhara ura.

Ndingamira Rini Kutora Plecanatide?

Unogona kumira kutora plecanatide kana chiremba wako achiona zvakakodzera, kazhinji kana zviratidzo zvako zvekuvhara ura zvavandudzwa zvakanyanya uye nguva dzose. Zvisinei, vanhu vazhinji vane kupera ura kusingaperi vanoda kurapwa kuri kuenderera mberi kuti vachengetedze basa retsika rematumbo.

Usamira kutora plecanatide usati wambotaura nachiremba wako, nekuti zviratidzo zvako zvinogona kudzoka. Chiremba wako anogona kukurudzira kuderedzwa zvishoma nezvishoma kana kukurudzira shanduko dzemaitiro ekubatsira kuchengetedza kuvandudzwa kwako.

Kana uchida kukurukura kumisa mushonga, taura nachiremba wako nezvekunetsekana kwako uye shandai pamwechete kugadzira chirongwa chinochengetedza hutano hwako hwekugaya chikafu.

Ndingatora Plecanatide nemamwe maLaxatives here?

Kazhinji, haufanire kutora plecanatide nemamwe ma laxatives kunze kwekunge chiremba wako achikurudzira zvakananga. Kubatanidza laxatives kunogona kuwedzera njodzi yako yekurwadziwa mudumbu, kupera mvura mumuviri, uye kusagadzikana kwe electrolyte.

Kana iwe uchitora mamwe mishonga yekuzvimbirwa, taura nachiremba wako kuti ungachinja sei zvakachengeteka ku plecanatide. Vanogona kukurudzira kumisa mamwe ma laxatives usati watanga plecanatide kana kukurudzira nguva chaiyo yekuronga.

Gara uchizivisa chiremba wako nezve mishonga yese uye zvinowedzerwa zvauri kutora kudzivirira kusangana kunogona kukuvadza.