Chii chinonzi Polymyxin B Injection: Zvayinoshandiswa, Madosi, Mativi eMuviri, nezvimwe

Polymyxin B injection mushonga une simba weantibiotic vanachiremba vanoshandisa kurapa zvirwere zvakakomba zvebacterial apo mamwe maantibiotics asina kushanda. Mushonga uyu ndeweboka rinonzi polymyxin antibiotics, uye wakagadzirirwa kurwisa mhando dzemabhakitiriya dzinogona kukonzera zvirwere zvinotyisa upenyu. Kunyange zvichionekwa semushonga une simba une mativi emuviri, inoshanda seimwe nzira yekurapa yakakosha kana iwe uchitarisana nezvirwere zvakakomba zvinoramba mamwe marapirwo.

Chii chinonzi Polymyxin B?

Polymyxin B iantibiotic inoshanda nekuparadza rusvingo rwekunze rwemamwe mabhakitiriya, zvichivaparadza kubva kunze mukati. Ndizvo zvinonzi vanachiremba "nzira yekupedzisira" antibiotic nekuti yakachengeterwa zvirwere zvakakomba zvinokonzerwa nemabhakitiriya egram-negative asingapinduri kune maantibiotics akachengeteka. Funga nezvazvo sechishandiso chakakosha icho vanachiremba vanosvika pavanoda chimwe chinhu chakasimba kurwisa zvirwere zvakaoma.

Mushonga uyu wavepo kubvira kuma1940, uye nepo maantibiotics matsva akagadzirwa, polymyxin B inoramba ichikosha pakurapa mhando dzemabhakitiriya anoramba. Inowanikwa chete sejekiseni nekuti inoda kupihwa zvakananga muropa rako kuti ive inoshanda zvakanyanya.

Polymyxin B Inoshandiswa Kunei?

Polymyxin B injection inorapa zvirwere zvakakomba zvebacterial izvo mamwe maantibiotics asingakwanise kubata zvakanaka. Chiremba wako angakunyore kana uine chirwere chakakomba uye bvunzo dzekurabhoritari dzichiratidza kuti mabhakitiriya anokonzera chirwere chako anoramba mamwe marapirwo. Inonyanya kubatsira pazvirwere muropa rako, mapapu, kana nzira yeweti.

Mhando dzehutachiona hunogona kuda polymyxin B zvinosanganisira pneumonia, sepsis (hutachiona hweropa), uye hutachiona hweurinary tract hunokonzerwa nemabhakitiriya akaita sePseudomonas aeruginosa, Acinetobacter, kana mamwe marudzi eE. coli. Mabhakitiriya aya akagadzira kuramba kune akawanda maantibayoti akajairika, zvichiita kuti polymyxin B ive sarudzo yakakosha yekurapa.

Mune dzimwe nguva, vanachiremba vanoshandisawo polymyxin B pakurapa hutachiona mudumbu rako kana hutachiona hunoitika mushure mekuvhiyiwa. Sarudzo yekushandisa mushonga uyu inogara ichiuya mushure mekunyatsofunga nezve hutachiona hwako chaihwo uye mhedzisiro yetsika yemabhakitiriya.

Polymyxin B Inoshanda Sei?

Polymyxin B inoshanda nekunangana nemumvuri wekunze wemabhakitiriya, kunyanya mabhakitiriya egram-negative. Inosungirirwa kuzvikamu mumadziro ebhakitiriya maseru anonzi lipopolysaccharides, izvo zvinokonzera kuti madziro eseru aparadzwe uye abude. Iyi nzira inopedzisira yauraya mabhakitiriya anokonzera hutachiona hwako.

Mushonga uyu unoonekwa seune simba rakanyanya munyika yeantibayoti. Kunyange simba iri richiiita kuti rive rinoshanda pamabhakitiriya anoramba, zvinorevawo kuti rinogona kukanganisa maseru ako pachako kusvika padhigirii, ndosaka vanachiremba vachikutarisa zvakanyanya panguva yekurapa. Mushonga unoshanda nekukurumidza kana wasvika panzvimbo yeutachiona kuburikidza neropa rako.

Nekuti polymyxin B ine simba rakanyanya, vanachiremba vanowanzoishandisa chete kana zvichidikanwa. Haisi antibiotic yekutanga-sarudzo, asi chishandiso chine simba chakachengeterwa mamiriro ezvinhu apo maantibayoti akapfava asina kubudirira.

Ndingatora Sei Polymyxin B?

Polymyxin B jekiseni rinogara richipiwa nenyanzvi dzehutano muchipatara kana munzvimbo yekiriniki. Hauzotore mushonga uyu kumba nekuti unoda kunyatso tarisa uye kupa kwakaringana. Mushonga unowanzo kupiwa kuburikidza neIV (intravenous) mutsara zvakananga mutsinga yako, zvichimuita kuti atenderere mumuviri wako nekukurumidza.

Vashandi venyu vezvehutano vachakupai jekiseni zvishoma nezvishoma kwenguva yeawa 1-2. Kupa mushonga uyu zvishoma nezvishoma kunobatsira kuderedza njodzi yezvinhu zvisingadiwi uye kunobvumira muviri wenyu kuti ugone kubata mushonga uyu zviri nani. Nguva chaiyo uye nzira inogona kusiyana zvichienderana nemamiriro enyu chaiwo uye kuti muviri wenyu unopindura sei kurapwa.

Panguva yekurapwa, hamufaniri kunetseka nezvekudya zvinorambidzwa kana kutora mushonga uyu pamwe chete nekudya sezvo uchipihwa zvakananga muropa renyu. Zvisinei, kugara uine mvura yakawanda kwakakosha, saka vashandi venyu vezvehutano vanogona kukukurudzirai kuti munwe mvura yakawanda kunze kwekunge paine chikonzero chekurapa chekudzivirira izvi.

Vashandi venyu vezvekurapa vachatarisa kushanda kwematsvo enyu, kunzwa, uye kupindura kwese kumushonga uyu panguva yekurapwa kwenyu. Vachachinja chiyero chemushonga kana nguva kana zvichidikanwa zvichienderana nekuti muviri wenyu uri kubata sei mushonga uyu.

Ndingatora Polymyxin B kwenguva yakareba sei?

Kureba kwekurapwa kwenyu kwe polymyxin B kunoenderana nerudzi uye kuoma kwehutachiona hwenyu, pamwe nekukurumidza kwemuiviri wenyu unopindura kumushonga uyu. Mazhinji ekurapwa anogara pakati pe7 kusvika ku14 mazuva, asi izvi zvinogona kusiyana zvakanyanya zvichienderana nemamiriro enyu ega.

Chiremba wenyu achatarisa zviratidzo zvehutachiona hwenyu kuburikidza nekuongororwa kweropa uye mamwe maongorwo kuti aone kana zvakachengeteka kumisa mushonga uyu. Vachatsvaga zviratidzo zvekuti mabhakitiriya ari kubviswa uye kuti muviri wenyu uri kupora zvakanaka. Zvimwe zvirwere zvinogona kuda makosi mapfupi emazuva 5-7, nepo zvirwere zvakanyanya kana zvakaoma zvinogona kuda nguva refu yekurapwa.

Zvakakosha kupedzisa nzira yese yekurapwa, kunyangwe ukatanga kunzwa zviri nani usati wapedza. Kumisa nekukurumidza kunogona kubvumira mabhakitiriya kuti ararame uye anogona kukudziridza kuramba kwakawanda kumishonga inorwisa mabhakitiriya. Vashandi venyu vezvehutano vachaita chero zvisarudzo zvekuchinja kana kumisa kurapwa kwenyu zvichienderana nekufambira mberi kwenyu uye mhedzisiro yebvunzo.

Ndezvipi Zvakaipa Zvinokonzerwa nePolymyxin B?

Semishonga yakawanda ine simba, polymyxin B inogona kukonzera matambudziko, kunyangwe kwete munhu wese achiwana iwo. Zvakaipa zvakajairika zvinowanzo manejwa uye zvinowanzoita nani muviri wako paunojaira mushonga kana mushure mekupera kwekurapa.

Hezvino zvakaipa zvaungawana, uye zvakakosha kuyeuka kuti timu yako yehutano iri kukutarisa zvakanyanya kuti ibate uye igadzirise chero nyaya nekukurumidza:

Zvakajairika zvinosanganisira:

• Kurwadziwa, kutsvuka, kana kuzvimba panzvimbo yekujekesa
• Kusvotwa kana dumbu rinogumbuka
• Dizziness kana kunzwa lightheaded
• Musoro
• Meno emuviri kana kukwenya
• Kushaya simba kwemhasuru kana kuneta

Zvimwe zvakaipa zvakakomba zvinoda kutariswa kwekurapa nekukurumidza zvinosanganisira:

• Matambudziko eitsvo (kuchinja mukuyera, kuzvimba mumakumbo kana tsoka)
• Kunzwa kuchinja kana kurira munzeve
• Zvakanyanya allergic reactions (kuoma kufema, rash yakakomba, kuzvimba kwechiso kana huro)
• Zviratidzo zvepfungwa (kusagadzikana, seizures, dizziness yakakomba)
• Kushaya simba kwemhasuru kana kuoma mitezo

Timu yako yehutano inokutarisa zvakanyanya kuti uwane izvi zvakanyanya kukomba, kunyanya basa reitsvo uye kunzwa kuchinja, izvo zvakanyanya kukonzera matambudziko. Vachaongorora ropa rako nguva dzose uye vachibvunza nezve chero zviratidzo zvauri kuwana.

Zvakawanda zvakaipa zvenguva pfupi uye zvinopera mushure mekupera kwekurapa. Zvisinei, mumamiriro ezvinhu asingawanzoitiki, zvimwe zvinokanganisa kunzwa kana basa reitsvo zvinogona kuramba, ndosaka vanachiremba vachishandisa mushonga uyu chete kana zvakakosha.

Ndiani Asingafaniri Kutora Polymyxin B?

Vanhu vakati wandei havafaniri kupiwa jekiseni re polymyxin B, uye chiremba wako achanyatsoongorora nhoroondo yako yezvokurapa asati akuraira. Chinhu chinonyanya kukosha ndechokuti wakambove ne allergic reaction ku polymyxin B kana maantibiotics akafanana munguva yakapfuura.

Chiremba wako achanyatso chenjerera nezvekukuraira polymyxin B kana uine matambudziko eitsvo, sezvo mushonga uyu unogona kuwedzera kushanda kweitsvo. Vachanyatso fungawo nezve njodzi kana uine matambudziko ekunzwa kana nhoroondo yezvirwere zvekusimba kwemhasuru zvakaita se myasthenia gravis.

Kana uri nepamuviri kana kuyamwisa, chiremba wako achayerera mabhenefiti achipesana nenjodzi dzinogona kuitika zvakanyanya. Kunyange polymyxin B ingave yakakosha kune zvirwere zvakakomba, vachakutarisa iwe nemwana wako zvakanyanya kana kurapwa kuchidiwa.

Vanhu vari kutora mamwe mishonga, kunyanya avo vanogona kukanganisa kushanda kweitsvo kana kunzwa, vangada kuongororwa zvakakosha kana kugadziriswa kwezvikamu. Chikwata chako chehutano chichaongorora mishonga yako yese kuti ive nechokwadi chekurapa kwakachengeteka.

Mazita ePolymyxin B Brand

Zita rinowanzozivikanwa re polymyxin B jekiseni ndeye Poly-Rx. Zvisinei, mushonga uyu unowanikwawo semushonga we generic, zvinoreva kuti unogona kuuwana pasi pezita rayo re generic

Nepo polymyxin B rinowanzo shandiswa pakurwisa zvirwere zvinodzivira mishonga, dzimwe nguva kune mamwe maantibiotics anogona kushanda mumamiriro ako chaiwo. Mamwe maantibiotics aya anoenderana nerudzi rwebhakitiriya riri kukonzera chirwere chako uye maitiro avanodzivira.

Mamwe maantibiotics ayo vanachiremba vangafunga kusanganisira colistin (iyo yakafanana zvikuru ne polymyxin B), mamwe maantibiotics matsva e beta-lactam, kana kurapwa kwakabatanidzwa vachishandisa maantibiotics akawanda pamwe chete. Mune dzimwe nguva, tigecycline kana maantibiotics matsva se ceftazidime-avibactam anogona kuva sarudzo.

Sarudzo ye antibiotic inogara ichienderana nemhedzisiro yako chaiyo yetsika yebhakitiriya uye bvunzo yekunzwa. Chiremba wako achasarudza mushonga wakakodzera zvichienderana nezviri kuitika zvakanyanya kurwisa chirwere chako chakati wandei uchikonzera mashoma mashoma emigumisiro.

Dzimwe nguva, kurapwa kwakabatanidzwa vachishandisa polymyxin B nemamwe maantibiotics kunoshanda zvakanyanya pane kushandisa chero antibiotic imwe chete. Chikwata chako chehutano chichasarudza nzira yakanakisa zvichienderana nemamiriro ako ega.

Ko Polymyxin B iri nani pane Colistin?

Polymyxin B na colistin maantibiotics akafanana zvikuru ayo ari emhuri imwe chete uye anoshanda nenzira dzakafanana. Ose ari maviri anoonekwa seanoshanda zvakaenzana kurwisa mabhakitiriya anodzivira gram-negative, uye sarudzo pakati pavo inowanzoenderana nekuwanikwa uye zvaunofarira chiremba wako.

Zvimwe zvidzidzo zvinoratidza kuti polymyxin B inogona kuve nyore pamatsvo zvichienzaniswa ne colistin, asi ese ari maviri mishonga ane njodzi dzakafanana uye anoda kunyatsoongororwa. Musiyano mumaprofiles emigumisiro mudiki, uye ese ari maviri mishonga anoonekwa sesarudzo dzakakodzera zvirwere zvinodzivira.

Sarudzo yachiremba wako pakati pemishonga miviri iyi inogona kuenderana nezvinhu zvakaita sebasa rematsvo ako, mhedzisiro yetsika yebhakitiriya, kana kuti mushonga upi unowanikwa nyore muchipatara chako. Mishonga yose miviri iyi inoshanda kurapa zvirwere zvakakomba zvinodzivira mishonga.

Mune dzimwe nguva, chiremba wako anogona kuchinja kubva kune mumwe kuenda kune mumwe zvichienderana nekuti uri kupindura sei kurapwa kana kana mhedzisiro yakaipa ikaitika. Chinhu chakakosha ndechokuti uri kuwana kurapwa kwakakodzera kwechirwere chako, zvisinei nekuti mushonga upi wepolymyxin unoshandiswa.

Mibvunzo Inowanzo Bvunzwa Pamusoro pePolymyxin B

Q1. Polymyxin B Yakachengeteka Kune Vanhu vane Chirwere cheMatsvo here?

Polymyxin B inoda kungwarira zvakanyanya muvanhu vane chirwere cheitsvo nekuti inogona kuwedzera basa rematsvo. Zvisinei, vanachiremba dzimwe nguva vanoraira mushonga uyu wezvirwere zvakakomba kana mabhenefiti achipfuura njodzi. Kana uine matambudziko ematsvo, chiremba wako anogona kugadzirisa mushonga wako uye achatarisa basa rematsvo ako zvakanyanya panguva yekurapwa.

Vashandi vehutano vachatarisa ropa rako kakawanda kuti vaone kuti itsvo dzako dziri kubata mushonga zvakanaka. Vanogona zvakare kuona kuti wakanyatsogadzirwa mvura uye kudzivisa mamwe mishonga anogona kuwedzera kushushikana kwematsvo ako panguva yekurapwa.

Q2. Ndingaita Sei Kana Ndikawana Polymyxin B yakawandisa netsaona?

Sezvo polymyxin B ichingopiwa nevashandi vehutano munzvimbo dzekiriniki, kuwandisa netsaona hakusi kwakajairika. Kana uine hanya nemushonga wako kana uchiona zviratidzo zvisingawanzoitiki panguva yekurapwa, zivisa vashandi vehutano vako nekukasira. Vanogona kuongorora mamiriro ako uye kupa kutarisirwa kwakakodzera kana zvichidikanwa.

Vashandi vako vezvokurapa vanotarisa mushonga wako zvakanyatso uye vanouchinja zvichienderana nehuremu hwako, basa rematsvo, uye kupindura kurapwa. Vakadzidziswa kuziva zviratidzo zvemigumisiro yemishonga uye vachatora matanho akakodzera kana chero matambudziko akamuka.

Mubvunzo weQ3. Ndingaita Sei Kana Ndakakanganwa Dose yePolymyxin B?

Sezvo polymyxin B ichipiwa nenyanzvi dzehutano muchipatara kana munzvimbo yekiriniki, iwe pachako hauzove nemhosva yekutara nguva dzako. Chikwata chako chehutano chinotarisira chirongwa chako chemishonga uye chinovimbisa kuti unogamuchira madosi panguva dzakakodzera.

Kana pakambove nekunonoka mumadosi ako akatarwa nekuda kwezvirongwa zvekurapa kana dzimwe nzira, chikwata chako chehutano chichagadzirisa chirongwa chako chekurapa zvinoenderana. Vachavimbisa kuti unogamuchira nzira yakazara yekurapa iyo hutachiona hwako hunoda.

Mubvunzo weQ4. Ndingamira Rini Kutora Polymyxin B?

Haufanire kumisa kurapwa kwe polymyxin B wega, kunyangwe ukanzwa zviri nani. Sarudzo yekumisa kurapwa inogara ichiitwa nechikwata chako chehutano zvichibva pamakero ako ehutachiona, kuvandudzwa kwekiriniki, uye kupedzwa kwenzira yakatarwa.

Chiremba wako achatarisa kufambira mberi kwako kuburikidza nemiedzo yeropa uye kuongororwa kwemuviri kuti aone kuti zvakachengeteka rini kumisa mushonga. Kumira nekukurumidza kunogona kubvumira mabhakitiriya kuti ararame uye anogona kukudziridza kuramba kwakawanda, zvichiita kuti hutachiona hwemunguva yemberi huve hwakaoma kurapa.

Mubvunzo weQ5. Ndingakwanisa Kukudziridza Kuramba kuPolymyxin B?

Nepo kuramba kwebhakitiriya ku polymyxin B kuchigona kukura, kuchiri kushoma zvichienzaniswa nekushora kune mamwe maantibayoti. Zvisinei, ichi ndicho chimwe chikonzero nei madhokotera achichengetera mushonga uyu kuzvirwere zvakakomba uye vanovimbisa kuti unopedza nzira yakazara yekurapa.

Kutora mushonga sezvakanyorwa uye kupedzisa nzira yese yekurapa kunobatsira kudzivirira kukura kwekudzivirira. Chikwata chako chehutano chinoshandisa polymyxin B zvine hungwaru kuchengetedza kushanda kwayo kune varwere vemunguva yemberi vangada iyo yezvirwere zvinotyisa hupenyu.