Chii chinonzi Raloxifene: Zvinoshandiswa, Madosi, Migumisiro uye Zvimwe

Raloxifene mushonga unopiwa nachiremba unobatsira kuchengetedza mapfupa ako uye kuderedza njodzi yako yezvimwe zvirwere mushure mekuenda kumwedzi. Iyo ndeyeboka remishonga inonzi selective estrogen receptor modulators (SERMs), zvinoreva kuti inogona kuita se estrogen mune dzimwe nzvimbo dzemuviri wako uku ichivharisa mhedzisiro ye estrogen mune dzimwe.

Mushonga uyu unonyanya kushandiswa kudzivirira nekurapa osteoporosis muvakadzi vakapfuura kuenda kumwedzi, ukuwo uchipa dziviriro kubva kune gomarara rezamu. Fungidzira se nzira yakatarwa inokupa zvimwe zvezvakanakira zve estrogen zvekuchengetedza mapfupa pasina kuwedzera njodzi mune dzimwe nzvimbo dzakaita sematishu ezamu.

Chii chinonzi Raloxifene chinoshandiswa?

Raloxifene inoshanda zvinangwa zviviri zvakakosha kuvakadzi vakapfuura kuenda kumwedzi. Chekutanga, inobatsira kudzivirira nekurapa osteoporosis nekusimbisa mapfupa ako uye kuderedza njodzi yekutyoka. Chechipiri, inogona kuderedza mikana yako yekuvandudza gomarara rezamu rinopinda.

Chiremba wako angangokupa raloxifene kana iwe uri panjodzi huru ye osteoporosis nekuda kwemhuri, kuenda kumwedzi kare, kana kutyoka kwakapfuura. Inofungidzirwawo kana iwe uine njodzi yakawedzera yegomarara rezamu asi usingakwanise kutora mamwe mishonga yekudzivirira.

Mishonga inoshanda zvakanaka kunyanya kuvakadzi vanoda kuchengetedzwa kwemapfupa asi vachida kudzivirira hormone replacement therapy. Inopa zvakanakira zvakanangwa kwazvinodiwa zvakanyanya uku ichideredza mhedzisiro isingadiwi mune dzimwe nzvimbo dzemuviri wako.

Raloxifene inoshanda sei?

Raloxifene inoshanda nekutevedzera mhedzisiro yakanaka ye estrogen pamapfupa ako uku ichivharisa mhedzisiro yayo inogona kukuvadza pamatishu ezamu uye uterine. Inofungidzirwa semushonga une simba zvine mwero unopa dziviriro inoreva kana ichishandiswa nguva dzose.

Mumapfupa ako, raloxifene inobatsira kuchengetedza kuwanda kwemapfupa nekuderedza mwero uyo muviri wako unoputsa matishu emapfupa. Maitiro aya anobatsira kuchengetedza mapfupa ako akasimba uye anodereredza njodzi yako yekutyoka, kunyanya mumuzongoza wako nemagaro.

Panguva imwecheteyo, raloxifene inodzivisa estrogen receptors mumutishu wemazamu, izvo zvinogona kubatsira kudzivirira kukura kwemarudzi akati wandei ekenza yemazamu. Chiito ichi chine zvikamu zviviri chinoita kuti ive sarudzo inokosha kuvakadzi vanoda kuchengetedzwa kwemapfupa nekudzivirirwa kwekenza.

Ndingatora sei Raloxifene?

Tora raloxifene sezvakanyorwa nachiremba wako, kazhinji kamwe pazuva chero nguva yezuva. Unogona kuitora uine chikafu kana usina, uye hapana chikonzero chekunetseka nezvekuisa nguva yayo nezvikafu.

Medza piritsi rose negirazi remvura izere. Usapwanye, kuputsa, kana kutsenga piritsi, sezvo izvi zvinogona kukanganisa mashandiro emushonga mumuviri wako.

Zvakakosha kutora raloxifene panguva imwechete zuva rega rega kuti uchengetedze mazinga akagadzikana muhurongwa hwako. Vanhu vazhinji vanozviwana zvichibatsira kubatanidza kutora mishonga yavo kune tsika yezuva nezuva, senge kukwesha mazino avo kana kudya kwemangwanani.

Ita shuwa kuti uri kuwana calcium yakakwana uye vhitamini D paunenge uchitora raloxifene, sezvo izvi zvinovaka muviri zvinoshanda pamwechete kutsigira hutano hwemapfupa. Chiremba wako anogona kukurudzira zvinowedzerwa kana chikafu chako chisina huwandu hwakakwana.

Ndingatora Raloxifene kwenguva yakareba sei?

Kureba kwekurapa kwe raloxifene kunosiyana zvichienderana nezvido zvako zvemunhu uye zvinangwa zvehutano. Vakadzi vazhinji vanoitora kwemakore akati wandei kuchengetedza kuchengetedzwa kwemapfupa uye kuderedza njodzi yekenza yemazamu.

Chiremba wako achatarisa nguva dzose kufambira mberi kwako kuburikidza nemiedzo yekuwanda kwemapfupa, basa reropa, uye bvunzo dzemuviri. Aya maekisesa anobatsira kuona kana mushonga uri kushanda nemazvo uye kana iwe uchifanira kuramba uchiutora.

Vakadzi vamwe vangada kutora raloxifene kwemakore mazhinji, kunyanya kana vaine njodzi dzinoenderera mberi dze osteoporosis kana gomarara rezamu. Vamwe vangachinja kune dzimwe nzira dzekurapa sezvo zvinodiwa zvehutano hwavo zvichichinja nekufamba kwenguva.

Usambomira kutora raloxifene kamwe kamwe usina kubvunza chiremba wako. Vachakubatsira kugadzira chirongwa chinovimbisa hutano hwemapfupa ako huri kuenderera mberi nekudzivirirwa kwegomarara kana iwe uchida kumisa mushonga.

Ndezvipi Zvakaipa ZveRaloxifene?

Vakadzi vazhinji vanotsungirira raloxifene zvakanaka, asi semishonga yese, inogona kukonzera mhedzisiro. Mashoko akanaka ndewekuti mhedzisiro yakawanda yakapfava uye inowanzoita nani sezvo muviri wako uchigadzirisa kumushonga.

Heano mhedzisiro yakajairika yaungasangana nayo:

• Kupisa kwemuviri uye kutukwa
• Kukakavara kwemakumbo, kunyanya usiku
• Kuzvimba mumaoko, tsoka, kana zvitsitsinho
• Zviratidzo zvakaita sefuruwenza
• Kurwadziwa kwemajoini kana kuoma
• Kutukwa kwakawedzera

Zviratidzo izvi zvinowanzo manejwa uye hazvidi kumisa mushonga. Chiremba wako anogona kukurudzira nzira dzekuderedza kusagadzikana iwe uchigadzirisa kurapwa.

Nepo zvisingawanzoitiki, vamwe vakadzi vanogona kusangana nemhedzisiro yakakosha inoda kutariswa:

• Kurwadziwa kwakanyanya kwemakumbo kana kuzvimba
• Kufema kwemhepo kamwe kamwe
• Kurwadziwa muchipfuwo
• Kurwadziwa kwemusoro kwakanyanya
• Kuchinja kwechiratidzo
• Kubuda ropa kwevagina kusinganzwisisike

Bata chiremba wako nekukasira kana ukaona chero zviratidzo izvi zvakakomba, sezvo zvingaratidza matambudziko anoda kutariswa kwekurapa nekukurumidza.

Kune zvakare njodzi diki asi yakakosha yegomarara reropa, kunyanya mumakumbo kana mumapapu. Njodzi iyi yakakwira panguva dzekusafamba kwenguva yakareba, senge ndege refu kana kurara pamubhedha mushure mekuvhiyiwa.

Ndiani Asingafaniri Kutora Raloxifene?

Raloxifene haikodzeri munhu wese, uye kune mamiriro akati wandei akakosha apo haifaniri kushandiswa. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akurudzira mushonga uyu.

Haufaniri kutora raloxifene kana iwe:

• Wakazvitakura kana ungazvitakura
• Uri kuyamwisa
• Usati wapfuura menopause
• Une nhoroondo yegomarara reropa
• Une chirwere chechiropa
• Une allergic ku raloxifene kana zvigadzirwa zvayo

Izvi zvinokonzera kunetseka kwekuchengeteka kunodarika mabhenefiti anogona kubatsira ekurapa. Chiremba wako achakurukura dzimwe sarudzo kana raloxifene isiri yakanaka kwauri.

Mamwe mamiriro ekurapa anoda kungwarira kwakanyanya uye kunyatsoongorora:

• Nhoroondo yesitiroko kana chirwere chemoyo
• High blood pressure
• Tsika yekusvuta
• Kugara pamubhedha kwenguva yakareba kana kusashanda
• Nhoroondo yekurova kwemoyo kusingaite
• Matambudziko eitsvo kana chiropa

Kana uine chero mamiriro aya, chiremba wako achayerera njodzi nemabhenefiti zvakanyatso chenjerera asati akurudzira raloxifene. Vanogona kukurudzira kuongorora kakawanda kana dzimwe nzira dzekurapa.

Mazita eRaloxifene Brand

Raloxifene inowanikwa pasi pezita rekuti Evista munyika zhinji. Iyi ndiyo vhezheni inonyanya kurairwa yemushonga uye yakanyatsoongororwa kuchengeteka uye kushanda.

Mhando dzemajenari dzeraloxifene dziripo zvakare uye dzine chinhu chimwe chete chinoshanda semushonga wemhando. Izvi zvingasarudzwa zvemajeneriki zvinowanzo dhura zvichipa mabhenefiti akaenzana.

Kunyangwe iwe ukagamuchira zita remhando kana raloxifene yegeneric, mushonga unoshanda nenzira imwechete. Murapi wako wemishonga anogona kukubatsira kunzwisisa kuti ndeipi vhezheni yaunogamuchira uye kupindura chero mibvunzo pamusoro pemisiyano pakati pefomula.

Dzimwe Sarudzo dzeRaloxifene

Mishonga mimwe yakawanda inogona kubatsira kuchengetedza mapfupa uye kudzivirira gomarara rezamu kana raloxifene isiri iyo yakakunakira. Chiremba wako achatarisa zvaunoda zvakajeka uye hutano hwako paanenge achikurudzira dzimwe nzira.

Kudzivirira nekurapa osteoporosis, dzimwe sarudzo dzinosanganisira:

• Bisphosphonates senge alendronate kana risedronate
• Denosumab majekiseni
• Teriparatide ye osteoporosis yakakomba
• Hormone replacement therapy mune dzimwe nguva

Kudzivirira gomarara rezamu, dzimwe nzira dzinogona kusanganisira tamoxifen kana aromatase inhibitors, zvichienderana nezvinhu zvako zvaunoda uye nhoroondo yako yekurapa.

Imwe neimwe nzira ine mabhenefiti ayo uye migumisiro inogona kuitika. Chiremba wako achakubatsira kuenzanisa sarudzo uye kusarudza kurapwa kunokodzera zvinangwa zvako zvehutano uye mararamiro.

Ko Raloxifene Zviri Nani Pane Tamoxifen?

Raloxifene uye tamoxifen zvese zvinoshanda kudzivirira gomarara rezamu, asi zvinoshanda zvakasiyana zvishoma uye zvine akasiyana side effect profiles. Sarudzo pakati pavo inoenderana nemamiriro ako uye zvaunoda muhutano.

Raloxifene inogona kufarirwa kana iwe uchida kuchengetedzwa kwemapfupa uye kudzivirira gomarara rezamu, sezvo ichipa zvese mabhenefiti mumushonga mumwe. Iyo zvakare ine njodzi yakaderera yegomarara remuromo wechibereko ichienzaniswa ne tamoxifen.

Tamoxifen inogona kusarudzwa kana iwe usati wapfuura menopause kana uine njodzi yakanyanya yegomarara rezamu, sezvo ichitenderwa kune akawanda mamiriro. Zvisinei, haipi mabhenefiti akafanana ekudzivirira mapfupa se raloxifene.

Chiremba wako achatarisa zvinhu zvakaita sezera rako, menopause status, bone density, uye njodzi yegomarara paanenge achikurudzira sarudzo yakanakisisa kwauri. Mishonga yese miviri yakaratidzwa kuti inoshanda muzvidzidzo zvikuru zvekiriniki.

Mibvunzo Inowanzo Bvunzwa Nezve Raloxifene

Ko Raloxifene Yakachengeteka Here Kune Zvirwere Zvemoyo?

Raloxifene inogona kushandiswa nevakadzi vazhinji vane chirwere chemoyo, asi zvinoda kufunga zvakanyatsonaka nekutarisa. Mushonga uyu ungave unopa zvimwe zvinobatsira kumoyo nekubatsira kuchengetedza mazinga e cholesterol ane hutano.

Zvisinei, njodzi yeropa rinovhara inonetesa vakadzi vane mamwe mamiriro emoyo. Chiremba wako wemoyo uye chiremba anorayira mushonga vachashanda pamwechete kuti vaone kana raloxifene yakachengeteka kune hutano hwemoyo wako chaihwo.

Ndingaita Sei Kana Ndikatora Raloxifene Yakawandisa Netsaona?

Kana netsaona ukatora yakawanda kupfuura chiyero chako chakanyorwa, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira. Kunyange zvazvo mhedzisiro yakakomba yekuwandisa isingawanzoitiki, zvakakosha kuwana zano rekurapa nekukurumidza.

Usaedze kutsiva chiyero chakawedzerwa nekusvetuka chiyero chako chinotevera chakarongeka. Pane kudaro, tevera mirairo yachiremba wako uye dzokera kuchirongwa chako chekushandisa mushonga sezvakarairwa.

Ndingaita Sei Kana Ndikakanganwa Chiyero cheRaloxifene?

Kana ukakanganwa chiyero, tora nekukasira paunorangarira, kunze kwekunge yava nguva yechiyero chako chinotevera chakarongeka. Muchiitiko ichocho, svetuka chiyero chakakanganwa uye uenderere mberi nechikwata chako chetsika.

Usatore zviyero zviviri panguva imwe chete kuti utsigire chiyero chakakanganwa, sezvo izvi zvinogona kuwedzera njodzi yako yemhedzisiro. Kana iwe uchikanganwa zviyero kazhinji, funga kumisa chiyeuchidzo chezuva nezuva kana kushandisa murongi wepiritsi.

Ndingamira Rini Kutora Raloxifene?

Sarudzo yekumira raloxifene inofanira kugara ichiitwa mukubvunzana nachiremba wako. Vachafunga nezvehuwandu hwako hwemabhonzo, njodzi yekenza yemazamu, uye hutano hwese paunenge uchisarudza nguva yakakodzera yekumisa kurapwa.

Vamwe vakadzi vangangoda kuenderera mberi vachitora raloxifene kwemakore mazhinji, nepo vamwe vachigona kuchinjira kune dzimwe nzira dzekurapa sezvavanoda kuchinja. Chiremba wako achakubatsira kugadzira chirongwa chinochengetedza hutano hwemabhonzo ako nekudzivirirwa kwekenza.

Ndingatora Raloxifene nemimwe mishonga here?

Raloxifene inogona kushamwaridzana nemimwe mishonga, saka zvakakosha kuti uudze chiremba wako nezve mishonga yese nemamwe mavitamini aunotora. Dzimwe kushamwaridzana dzinogona kukanganisa mashandiro anoita raloxifene kana kuwedzera njodzi yako yekuwana mhedzisiro.

Nyatso tarisa mishonga inotetesa ropa, sezvo kuibatanidza ne raloxifene kunogona kuwedzera njodzi yekubuda ropa. Chiremba wako achachinja zviyero kana kuronga mamwe marapirwo kana zvichidikanwa kuti ave nechokwadi chekuchengeteka kwako.