Chii chinonzi Ramucirumab: Zvazvinoshandiswa, Mishonga, Zvazvinokonzera uye Zvimwe

Ramucirumab mushonga wekenza unovavarira kubatsira kunonotsa kukura kwebundu nekudzivisa ropa rinopa masero ekenza. Ndizvo zvinonzi nachiremba monoclonal antibody - chaizvoizvo protein yakagadzirwa murabhoritari inoshanda semuviri wako wega wega immune system kurwisa zvinhu zvakatarwa mukenza.

Mushonga uyu unoshanda zvakasiyana nemishonga yechinyakare yechemotherapy. Panzvimbo pekurwisa masero ese anokurumidza kukamurwa, ramucirumab inonyanya kutarisisa mapuroteni anobatsira mabhundu kugadzira midzi yeropa mitsva, iyo iri nzira yakarurama yekurapa kenza.

Chii chinonzi Ramucirumab chinoshandiswa?

Ramucirumab inorapa marudzi akati wandei ekenza yepamberi, kunyanya kana mamwe marapirwo asina kushanda sezvaitarisirwa. Oncologist wako anoraira mushonga uyu mumamiriro ezvinhu akatarwa apo kuvharisa kukura kwemidzi yeropa kunogona kubatsira kudzora kufambira mberi kwekenza.

Makenza makuru anorapwa ne ramucirumab anosanganisira kenza yedumbu yepamberi, mamwe marudzi ekenza yemumapapu, uye kenza yecolorectal yakapararira kune dzimwe nhengo dzemuviri. Inowanzo shandiswa pamwe chete nemimwe mishonga yekenza panzvimbo yega.

Chiremba wako anogona kukurudzira ramucirumab kana kenza yako yakafambira mberi pasinei nemarapirwo apfuura, kana sechikamu chechirongwa chekurapa chakasanganiswa. Mamiriro ezvinhu ese akasiyana, uye oncologist wako achatsanangura chaizvo kuti nei mushonga uyu uchikodzera chirongwa chako chekurapa.

Ramucirumab inoshanda sei?

Ramucirumab inovharisa protein inonzi VEGFR-2 iyo mabhundu anoshandisa kukura midzi yeropa mitsva. Funga nezvazvo sekudzima mitsara yekupa iyo inopa masero ekenza zvinovaka muviri zvavanoda kukura nekupararira.

Mushonga uyu unoonekwa sechirapa chakati wandei chinovavarira. Haina kuomarara pamuviri wako wese sechemotherapy yechinyakare, asi ichiri mushonga une simba unoda kutariswa zvakanyanya nechikwata chako chehutano.

Mushonga unoshanda nekubatanidza kune zvimwe zvinogamuchira pamaseru emidziyo yeropa, uchivadzivisa kugamuchira zviratidzo zvekukura. Izvi zvinobatsira kunyima bundu rekupa ropa ravanoda, izvo zvinogona kunonotsa kukura kwavo nekupararira.

Ndingatora Sei Ramucirumab?

Ramucirumab inopiwa chete kuburikidza neIV infusion pahofisi yachiremba wako kana nzvimbo yekupinza. Hauzive kutora mushonga uyu kumba - zvinoda kutariswa kwekurapa kwenyanzvi nguva imwe neimwe yaunogamuchira.

Infusion inowanzo tora maminitsi makumi matanhatu edosi yako yekutanga, uye chikwata chako chehutano chichakutarisa zvakanyanya panguva ino. Kana iwe ukashivirira infusion yekutanga zvakanaka, madosi emangwana anogona kupiwa pamusoro pemaminitsi makumi matatu.

Haufaniri kuita chero shanduko dzakakosha dzekudya usati waisa, asi kugara uine mvura yakawanda nekunwa mvura yakawanda mumazuva anotungamira kurapwa kwako kunogona kubatsira muviri wako kubata mushonga zviri nani. Chikwata chako chehutano chichakupa mirairo chaiyo yekudya nekunwa usati wagadzwa.

Pamberi peimwe neimwe infusion, iwe ungangodaro uchagamuchira pre-medications kubatsira kudzivirira maitiro ekuita allergic. Izvi zvinogona kusanganisira antihistamines kana mamwe mishonga kuti kurapwa kwako kuve kwakanyanya kunyaradza.

Ndingatora Kwenguva Yakareba Sei Ramucirumab?

Kureba kwekurapa kwe ramucirumab kunosiyana zvakanyanya kubva kumunhu nemunhu uye kunoenderana nekuti kenza yako inopindura sei uye kuti muviri wako unoshivirira sei mushonga. Vamwe vanhu vanoiwana kwemwedzi yakati wandei, nepo vamwe vachigona kuida kwenguva yakareba.

Oncologist wako achagadzirisa scans dzenguva dzose uye bvunzo dzeropa kuti atarise kuti kurapwa kuri kushanda sei. Aya mazuva ekutarisa anobatsira kuona kana uchienderera mberi, kugadzirisa, kana kumisa mushonga zvichibva pakupindura kwegomarara rako.

Kurapa kunowanzoenderera mberi kusvika kenza yako ichiwedzera, mativi emuviri ave akaoma kudzora, kana iwe nachiremba wako muchisarudza kuti inguva yekuedza imwe nzira. Sarudzo iyi inogara ichiitwa pamwechete zvichibva pamuviri wako wese nezvinangwa zvekurapa.

Ndezvipi Zvinhu Zvinokonzerwa neRamucirumab?

Semishonga yese yekenza, ramucirumab inogona kukonzera mativi emuviri, kunyangwe vanhu vese vasingaawane nenzira imwechete. Chikwata chako chekuchengetwa kwehutano chichakutarisa zvakanyanya uye kubatsira kudzora chero matambudziko anomuka.

Mativi emuviri anowanzoitika aunogona kusangana nawo anosanganisira kuneta, kuderedzwa kwechido, uye shanduko mudzihwa rako reropa. Vanhu vazhinji vanoonawo kuzvimba mumaoko avo kana tsoka, izvo zvinowanzoitika nekuchengetwa kwakakodzera.

Heano mativi emuviri anowanzoitika anokanganisa vanhu vazhinji vachitora ramucirumab:

• Kukwira kweropa kunogona kuda mushonga
• Kuneta kana kunzwa kuneta kupfuura zvakajairika
• Kuderedzwa kwechido uye kurasikirwa uremu kunogona kuitika
• Kutemwa nemusoro
• Kuzvimba mumaoko, tsoka, kana makumbo
• Dhiria kana shanduko mukufamba kwematumbo
• Nausea pasina kurutsa

Aya mativi emuviri anowanzoitika anowanzoitika nekuchengetwa kunotsigira uye mishonga kana zvichidikanwa. Chikwata chako chekuchengetwa kwehutano chine ruzivo rwekubatsira varwere vachipfuura nematambudziko aya.

Kune zvakare mamwe mativi emuviri asingawanzoitiki asi akakomba anoda kutariswa kwekurapa nekukasira. Kunyangwe izvi zvisingaitike kune vanhu vazhinji, zvakakosha kuziva zvekutarisa kuti ugone kuwana rubatsiro nekukurumidza kana zvichidikanwa.

Mativi emuviri akakomba anoda kutariswa kwekurapa nekukasira anosanganisira:

• Kubuda ropa kwakanyanya chero kupi zvako mumuviri mako
• Mavanga eropa anogona kukonzera kurwadziwa muchipfuva kana kufema zvishoma
• Maitiro akanyanya ekuita allergic panguva yekuiswa
• Matambudziko nekupona kwemavanga kana iwe uchida kuvhiyiwa
• Zvirwere zvakakomba nekuda kwehuwandu hweropa jena rakaderera
• Matambudziko eitsvo anoonekwa mumiedzo yeropa

Vashandi vehutano vachakutarisa zvakanyanya kuti uone mhedzisiro iyi yakakomba kuburikidza nemiedzo yeropa yenguva dzose uye kuongororwa. Vanhu vazhinji havawani matambudziko aya akakomba, asi kuziva zvekutarisa kunobatsira kuona kuti unowana kutarisirwa nekukurumidza kana zvichidikanwa.

Ndiani Asingafaniri Kutora Ramucirumab?

Ramucirumab haikodzeri munhu wese, uye oncologist yako ichanyatsoongorora nhoroondo yako yekurapa usati warumbidza kurapwa uku. Mamwe mamiriro ehutano kana mamiriro anoita kuti mushonga uyu uve njodzi kushandisa zvakachengeteka.

Haufanire kugamuchira ramucirumab kana wakazvitakura kana kuronga kuva nepamuviri, sezvo inogona kukuvadza zvakanyanya mwana ari kukura. Vakadzi vanogona kuva nepamuviri vanofanira kushandisa nzira yekudzivirira pamuviri inoshanda panguva yekurapwa uye kwemwedzi yakati wandei mushure meizvozvo.

Vanhu vane kuvhiyiwa kukuru kwemazuva ano, kubuda ropa kuri kushanda, kana matambudziko akakomba ekuita ropa rinowanzo gamuchira ramucirumab. Chiremba wako achavawo akangwarira kana uine ropa rakakwira risingadzoreki kana matambudziko akakomba emoyo.

Zvimwe zvirwere zvingaita kuti ramucirumab isakodzere zvinosanganisira chirwere cheitsvo chakakomba, kurwisa kwemoyo kana sitiroko ichangobva kuitika, kana nhoroondo yematambudziko akakomba ekubuda ropa. Vashandi vehutano vachaongorora zvese izvi zvikonzero vasati vatanga kurapwa.

Ramucirumab Mazita eBrand

Ramucirumab inotengeswa pasi pezita rekuti Cyramza. Iri ndiro zita rimwe chete remhando rinowanikwa remushonga uyu, sezvo iri mushonga wehunyanzvi webiologic wakagadzirwa nemugadziri mumwe chete.

Paunogamuchira kurapwa kwako, bhodhoro remushonga richanyorwa seCyramza, asi chikwata chako chekurapa chinowanzochitaura nezita rayo re generic, ramucirumab. Mazita ese ari maviri anoreva mushonga mumwe chete.

Zvimwe Zvinogona Kushandiswa Panzvimbo peRamucirumab

Mishonga yakati wandei inoshanda zvakafanana ne ramucirumab nekunangana nekukura kwemidzi yeropa mumaviri. Chiremba wako wezve oncology angangofunga nezvezvimwe zvingashandiswa kana ramucirumab isina kukodzera mamiriro ako kana kana uchida imwe nzira yekurapa.

Bevacizumab imwe mushonga unopesana neangiogenic unoshanda nekudzivisa VEGF panzvimbo yeVEGFR-2. Inoshandiswa kune akawanda emhando dzakafanana dzekenza uye inogona kuva sarudzo zvichienderana nekuongororwa kwako kwakatarwa uye nhoroondo yekurapa.

Mamwe marapirwo akatarwa se aflibercept kana regorafenib anogonawo kufungwa nezve mamwe marudzi ekenza. Chiremba wako wezve oncology achasarudza sarudzo yakanakisa zvichienderana nerudzi rwako rwekenza, kurapwa kwakapfuura, uye hutano hwako hwese.

Sarudzo pakati pemishonga iyi inoenderana nezvinhu zvakawanda, kusanganisira kuti ndedzipi kenza dzakabvumidzwa kurapa, maitiro avanoita nemimwe mishonga yaunotora, uye njodzi dzako dzega dzekuita mhedzisiro.

Ko Ramucirumab Ari Nani Kudarika Bevacizumab?

Ose ari maviri ramucirumab uye bevacizumab mishonga inoshanda inopesana neangiogenic, asi anoshanda zvishoma zvakasiyana uye anoshandiswa kune mamiriro akasiyana. Hapana imwe iri yakanakisa zvachose - sarudzo inoenderana nerudzi rwako rwekenza uye nhoroondo yekurapa.

Ramucirumab inodzivisa iyo VEGFR-2 receptor zvakananga, nepo bevacizumab ichidzivisa iyo VEGF protein inosunga kune iyo receptor. Musiyano uyu mumaitiro unogona kuita kuti imwe ive yakakodzera kupfuura imwe yemamiriro ako chaiwo.

Kenza yedumbu, ramucirumab yakaratidza mabhenefiti akatarwa akaita kuti ive sarudzo inofarirwa muzviitiko zvakawanda. Zvisinei, bevacizumab inogona kuva nani kune mamwe marudzi ekenza kana mamiriro ezvinhu apo ramucirumab isina kukodzera.

Chiremba wako wezvirwere zvegomarara achafunga nezvezvinhu zvakaita serudzi rwegomarara rako, kurapwa kwawakaitwa kare, mhedzisiro yezvinhu zvisingadiwi, uye hutano hwako hwese paanenge achisarudza pakati pemishonga iyi. Sarudzo "yakanaka" inogara iri iyo inogona kubatsira mamiriro ako chaiwo.

Mibvunzo Inowanzo Bvunzwa Nezve Ramucirumab

Ko Ramucirumab Yakachengeteka Kune Vanhu Vane Chirwere Chemoyo Here?

Ramucirumab inoda kufungwa zvakanyanya kana uine chirwere chemoyo, nekuti inogona kukanganisa ropa uye zvichida kuwedzera njodzi yeropa. Chiremba wako wemoyo uye chiremba wezvirwere zvegomarara vachashanda pamwechete kuti vaone kana mabhenefiti achikunda njodzi mumamiriro ako chaiwo.

Kana uine nhoroondo yematambudziko emoyo, timu yako yehutano ichakutarisa zvakanyanya panguva yekurapa. Vanogona kugadzirisa mishonga yako yemoyo kana kutora matanho ekuwedzera kuchengetedza hutano hwako hwemoyo nemitsipa paunenge uchigamuchira ramucirumab.

Ndoita Sei Kana Ndikashandisa Ramucirumab Yakawandisa Netsaona?

Sezvo ramucirumab ichingopiwa nevashandi vehutano munzvimbo dzekurapa, kuwandisa netsaona hakuiti. Mishonga inoyerwa zvakanyanya uye inopiwa nevashandi vekurapa vakadzidziswa vanotevera mitemo yakasimba.

Kana uine hanya nedosi yako kana uine zviratidzo zvisingawanzoitiki mushure mekuiswa, taura nechikwata chako chehutano nekukurumidza. Vanogona kuongorora mamiriro ako uye kupa kutarisirwa kwakakodzera kana zvichidikanwa.

Ndoita Sei Kana Ndikakanganwa Dosi yeRamucirumab?

Kana ukakanganwa kuisa ramucirumab yakarongwa, taura nehofisi yechiremba wako wezvirwere zvegomarara nekukurumidza sezvinobvira kuti urongezve. Usaedze kutsiva dosi yakarasika nekuwedzera - chiremba wako achasarudza nzira yakanakisisa yekudzokera kumaitiro ako ekurapa.

Kusavapo kwemushonga mumwe chete kazhinji hakuwanzo kukanganisa kurapwa kwako zvakanyanya, asi zvakakosha kuchengetedza nguva yakarongeka sezvinobvira kuti uwane mhedzisiro yakanaka. Chikwata chako chekuchengetedza hutano chichashanda newe kuti uwane nguva itsva yekugadzwa inoenderana nehurongwa hwako.

Ndingamira Rini Kutora Ramucirumab?

Unogona kumira kutora ramucirumab kana chiremba wako wezve oncology aona kuti haachabatsiri, kana mhedzisiro yacho yave yakaoma kwazvo kubata, kana kana iwe ukasarudza kuti kurapwa hakuchawirirani nezvinangwa zvako. Sarudzo iyi inofanira kugara ichiitwa pamwe chete nechikwata chako chekuchengetedza hutano.

Chiremba wako achagara achiongorora kuti mushonga uri kushanda sei kuburikidza nekuongorora uye bvunzo dzeropa. Kana kenza yako ikafambira mberi kana kana iwe ukawana mhedzisiro yakakomba, vanogona kukurudzira kumisa ramucirumab uye kutsvaga dzimwe nzira dzekurapa.

Ndingagamuchira Majekiseni Ndiri Kutora Ramucirumab Here?

Unogona kugamuchira majekiseni mazhinji uchitora ramucirumab, asi unofanira kudzivisa majekiseni mhenyu panguva yekurapa. Chiremba wako wezve oncology achapa gwara rakatarwa pamusoro pemajekiseni akachengeteka uye nguva yekuaronga.

Zvakakosha zvikuru kuti urambe uchiziva nezve majekiseni eflu uye majekiseni eCOVID-19 uchigamuchira kurapwa kwekenza, sezvo izvi zvinogona kukubatsira kukudzivirira kana immune system yako ingave yakakanganiswa. Nguva dzose kurukura zvirongwa zvekudzivirira nechikwata chako chekuchengetedza hutano usati watora chero majekiseni.