Ravulizumab-cwvz (inokisirwa muchipatara)
Mhando dzinowanikwa
Ultomiris
Nezve mushonga uyu
Jekiseni yeRavulizumab-cwvz inoshandiswa kurapa rudzi rweronda reropa runonzi paroxysmal nocturnal hemoglobinuria (PNH). Mushonga uyu unobatsira kuderedza kuparadzwa kweropa tsvuku kana kuputsika (hemolysis) muvarwere vane PNH. Jekiseni yeRavulizumab-cwvz inoshandiswawo kurapa atypical hemolytic uremic syndrome (aHUS) muvakuru nevana. Jekiseni yeRavulizumab-cwvz inoshandiswawo kurapa dambudziko renerve nemisumbu rinonzi generalized myasthenia gravis (gMG) muvarwere vane anti-acetylcholine receptor (AChR) antibody positive. Jekiseni yeRavulizumab-cwvz inoshandiswawo kurapa neuromyelitis optica spectrum disorder (NMOSD), chirwere chisingawanzoitika chinokonzera kuzvimba kwemitsipa yemaziso nemucheka wemuzongoza. Inoshandiswa muvarwere vane anti-aquaporin-4 (AQP4) antibody positive. Jekiseni yeRavulizumab-cwvz imhando ye monoclonal antibody inoshanda pane immune system. Mushonga uyu unowanikwa chete pasi pechirongwa chekugoverwa chinonzi Ultomiris® REMS (Risk Evaluation and Mitigation Strategy) Program. Chigadzirwa ichi chinowanikwa mumafomu anotevera ekurapa:
Usati washandisa mushonga uyu
Pakusarudza kushandisa mushonga, ngozi dzokutora mushonga iyeye dzinofanira kuyeranidzwa nezvakanaka zvichaita. Iyi sarudzo iwe nesachiremba wenyu muchaita. Kune mushonga uyu, zvinotevera zvinofanira kufungwa: Udza chiremba wako kana wakambonzwa chero chirwere chisina kujairika kana chisina kujairika kumushonga uyu kana mimwe mishonga. Uyewo udza nyanzvi yehutano hwako kana uine mamwe marudzi eallergies, akadai sekudya, dyes, preservatives, kana mhuka. Kune zvigadzirwa zvisinganyorwi, verenga zvinyorwa zvepakeji kana zvinhu zvakanyatsonaka. Kudzidza kwakakodzera kwakaitwa kusvika pari zvino hakuzive matambudziko chaiwo epediatric aizoita kuti kushandiswa kwe ravulizumab-cwvz injection kurapa paroxysmal nocturnal hemoglobinuria (PNH) uye atypical hemolytic uremic syndrome (aHUS) muvana vane mwedzi mumwe chete uye vakuru. Zvisinei, kuchengetedzeka uye kushanda hazvina kusimbiswa kurapa PNH uye aHUS muvana vane makore pasi pemwedzi mumwe chete, kana kurapa generalized myasthenia gravis (gMG) uye neuromyelitis optica spectrum disorder (NMOSD) muvana. Kudzidza kwakakodzera kwakaitwa kusvika pari zvino hakuzive matambudziko chaiwo egeriatric aizoita kuti kushandiswa kwe ravulizumab-cwvz injection muvakuru. Hapana zvidzidzo zvakakwana muvakadzi zvekuona ngozi yemwana pakushandisa mushonga uyu panguva yekuyamwisa. Yera mabhenefiti anogona kuitika pamwe nengozi dzinogona kuitika usati watora mushonga uyu panguva yekuyamwisa. Kunyange zvazvo mimwe mishonga isingafaniri kushandiswa pamwe chete, mune mamwe mamiriro mishonga miviri yakasiyana inogona kushandiswa pamwe chete kunyange kana kuwirirana kungavepo. Mumativi aya, chiremba wako angada kuchinja dose, kana mamwe matanho angave akakosha. Paunenge uchitora mushonga uyu, zvakakosha kuti nyanzvi yehutano hwako izive kana uri kutora chero mishonga iri pazasi. Kuwirirana kunotevera kwakasarudzwa zvichienderana nekuwanda kwavo uye hazvisi zvese zvinosanganisirwa. Kushandisa mushonga uyu nechero mishonga inotevera kazhinji hakuzombofungidzirwi, asi kungave kwakakosha mune zvimwe zviitiko. Kana mishonga yose ikanyorwa pamwe chete, chiremba wako angachinja dose kana kuti ungashandisa sei imwe kana ese mishonga. Mimwe mishonga haifaniri kushandiswa panguva kana pedyo nenguva yekudya kana kudya marudzi akati wandei ezvokudya sezvo kuwirirana kungavepo. Kushandisa doro kana fodya neimwe mishonga kunogona zvakare kukonzera kuwirirana kuitika. Kurukurai nehutano hwako hwenyanzvi kushandiswa kwemushonga wako nezvokudya, doro, kana fodya. Kuvapo kwemamwe matambudziko ehutano kunogona kukanganisa kushandiswa kwemushonga uyu. Ita shuwa kuti unoudza chiremba wako kana uine mamwe matambudziko ehutano, kunyanya:
Mashandisirwo aungaita mushonga uyu
Mufambiri kana mumwe munyanzvi wehutano akarovedzwa achakupa iwe kana mwana wako mushonga uyu muchipatara. Inopihwa kuburikidza ne catheter ye-IV inoiswa mumutsinga yako. Mushonga uyu unofanira kupihwa zvishoma nezvishoma. IV inowanzo gara kwenguva inosvika awa imwe kana isingasviki. Muzvimwe zviitiko, IV inogona kudiwa kuti igare kwenguva inosvika maawa mana. Chiremba wako achakurinda kweanenge awa imwe mushure mekuiswa kwemushonga chero zvipingamupinyi zvisingadiwi. Zvakakosha kuti unzwisise zvinodiwa nechirongwa cheUltomiris® REMS, uye uzive bhuku reMishonga yeUltomiris® nemirayiridzo yevagari venyika. Verenga utevedzere mirairo iyi zvakanyatsonaka. Bvunza chiremba wako kana uine mibvunzo. Bvunza mushonga wako kuti uwane bhuku reMishonga kana usina. Kana uri kuchinja kurapwa kubva kuSoliris® kuenda kuUltomiris®, unofanira kugamuchira chikamu chako chekutanga cheUltomiris® panguva yako inotevera yakarongwa yeSoliris®. Fonera chiremba wako kana mushonga wako kuti uwane mirairo.