Chii chinonzi Raxibacumab: Zvazvinoshandiswa, Madosi, Migumisiro Yakaipa nezvimwe

Raxibacumab mushonga wemuviri wakagadzirirwa kurapa muchetura weanthrax kana mabhakitiriya atopinda muropa rako. Kurapa uku kunoponesa upenyu kunoshanda nekudzivisa muchetura unokuvadza unoburitswa nemabhakitiriya eanthrax, zvichipa muviri wako mukana wekurwa kuti upore.

Zvichida hauzombo sangani nemushonga uyu mukutarisirwa kwekurapa kwenguva dzose. Raxibacumab yakachengeterwa mamiriro ekukurumidzira ane chekuita nebioterrorism kana kusangana netsaona nemaspore eanthrax, zvichiita kuti ive imwe yeanonyanya kurapwa mumishonga yemazuva ano.

Chii chinonzi Raxibacumab?

Raxibacumab imonoclonal antibody inonyanya kutarisana neanthrax toxin. Funga nezvayo semurindi akadzidziswa zvakanyanya anoziva uye anogadzirisa imwe ngozi chaiyo mumuviri wako.

Mushonga uyu ndewechikwata chemishonga inonzi immunoglobulins, iyo iri mhando dzakagadzirwa murabhoritari dzemuviri dzemuviri wako unowanzoita. Musiyano ndewekuti raxibacumab yakagadzirirwa kuve yakanyatsojeka, ichinanga chete chikamu cheantigen chinodzivirira cheanthrax toxin.

Kusiyana neantibiotics inouraya mabhakitiriya zvakananga, raxibacumab inoshanda nekubatanidza kune muchetura uyo mabhakitiriya akatoburitsa. Izvi zvinodzivirira muchetura kubva mukukuvadza maseru ako apo mamwe marapirwo anoshanda kubvisa hutachiona pachahwo.

Chii chinonzi Raxibacumab chinoshandiswa?

Raxibacumab inorapa inhalational anthrax, iyo inoitika kana iwe ukufema mumaspores eanthrax. Iyi ndiyo mhando ine njodzi zvikuru yeanthrax infection uye inogona kuuraya pasina kurapwa nekukurumidza.

Mushonga uyu unonyanya kuratidzwa kune zviitiko apo mabhakitiriya eanthrax atanga kuburitsa muchetura muropa rako. Panguva ino, maantibiotics ega angasava akakwana nekuti muchetura wemabhakitiriya unoenderera mberi nekukonzera kukuvadza kunyangwe mabhakitiriya aurayiwa.

Vapi vezvehutano vanoshandisawo raxibacumab sechiyero chekudzivirira kana wakambobatwa nemaspore eanthrax asi usati wava nezviratidzo. Kushandiswa uku kwe prophylactic kunokubatsira kukudzivirira panguva yakakosha apo spores inogona kunge ichikura mumapapu ako.

Muzviitiko zvisingawanzoitiki, vanachiremba vanogona kufunga nezve raxibacumab ye cutaneous anthrax (hutachiona hweganda) kana hutachiona huchiratidza zviratidzo zvekupararira muropa rako kana uine immune system yakakanganiswa.

Raxibacumab Inoshanda Sei?

Raxibacumab inofungidzirwa semushonga une simba uye wakatarwa uyo unoshanda zvakasiyana kubva kumishonga inorwisa mabhakitiriya yechinyakare. Inosungirira zvakananga ku anthrax protective antigen, ichidzivirira kuumbwa kwemakomputa ane chepfu anokuvadza masero ako.

Mabhakitiriya eanthrax paanoburitsa chepfu yawo, chepfu idzi dzinowanzo sungirirwa kumasero ako uye dzinobaya mapuroteni anokuvadza mukati. Raxibacumab inoshanda semukiyi wemamorekuru, ichisungirira kune protective antigen component uye ichidzivirira kupinda kwemasero uku kuti kuitike.

Mushonga hauurayi mabhakitiriya zvakananga, ndosaka uchigara uchishandiswa pamwe chete nemishonga inorwisa mabhakitiriya. Panzvimbo pezvo, inodzima chepfu apo mishonga inorwisa mabhakitiriya inobvisa hutachiona hwebhakitiriya, ichigadzira nzira yekudzivirira ine mativi maviri.

Nzira iyi yakakosha zvikuru nekuti anthrax toxins inogona kuramba ichikonzera kukuvadza kunyangwe mabhakitiriya afa. Nekudzima chepfu idzi, raxibacumab inobatsira kudzivirira cascade yekukuvadzwa kwemasero kunoita kuti anthrax ive njodzi.

Ndinofanira Kutora Sei Raxibacumab?

Raxibacumab inopiwa chete se intravenous infusion muchipatara kana nzvimbo yekurapa yakakosha. Hauzivi kutora mushonga uyu kumba, uye unoda kunyatsotariswa nevashandi vezvehutano.

Mushonga unopiwa kuburikidza nemuviri kwemaminitsi anenge 2 maawa nemaminitsi gumi nemashanu. Chikwata chako chehutano chichakutarisa zvakanyanya panguva uye mushure mekuiswa chero maitiro asina kunaka.

Hamufaniri kutsanya musati mapiwa raxibacumab, uye hapana zvekudya zvinotaurwa. Zvisinei, timu yako yezvokurapa ichaona kuti mune mvura yakakwana uye makasununguka musati matanga kuisa mushonga.

Nguva yekupa mushonga yakakosha. Kana muri kupiwa raxibacumab nekuda kwehutachiona hweanthrax, kurapwa kunofanira kutanga nekukurumidza mushure mekuongororwa. Kune prophylaxis mushure mekuratidzwa, mushonga unowanzo piwa mumazuva mashoma ekutanga mushure mekusangana kunofungidzirwa.

Ndingatora Raxibacumab Kwenguva Yakareba Sei?

Raxibacumab inowanzo piwa sedosi imwe chete, kunyangwe mune dzimwe nguva chiremba wenyu angakurudzira mamwe madosi. Sarudzo inoenderana nekukomba kwekuratidzwa kwenyu uye mhinduro yenyu pachako kumushonga.

Kune hutachiona hweanthrax, dosi rimwe rinowanzoita kuti zvinokuvadza zvisashande. Zvisinei, kana muine anthrax yakakomba kana kana mazinga ezvinokuvadza achiramba akakwira, timu yenyu yezvokurapa ingafunga nezveimwe dosi.

Kana ichishandiswa kune post-exposure prophylaxis, dosi rimwe rinowanzoita kuti muve nekudzivirirwa apo muviri wenyu unovaka ma antibodies awo. Zvazvinoitwa nemushonga zvinogona kugara kwemavhiki akati wandei, zvichipa muviri wenyu nguva yekuvaka mhinduro yechisikigo yekudzivirira.

Timu yenyu yehutano icharamba ichikutarisa kwemavhiki mushure mekuwana raxibacumab kuti ive nechokwadi chekuti mushonga uri kushanda nemazvo uye kuti ione chero mhedzisiro yakareba.

Ndezvipi Zvazvinoitwa neRaxibacumab?

Vanhu vazhinji vanotsungirira raxibacumab zvakanaka, asi semishonga yese, inogona kukonzera mhedzisiro. Zvinhu zvakajairika zvinowanzoita zvinyoro uye zvinogoneka nekuchengetedza.

Hezvino zvazvinoitwa zvaungasangana nazvo, kubva kune zvakajairika kusvika kune zvishoma:

• Kushatirwa panzvimbo yekuisirwa mushonga semuenzaniso kutsvuka, kuzvimba, kana kurwadziwa kudiki panzvimbo yeIV
• Kurwadziwa nemusoro kunowanzo pera mukati memaawa mashoma
• Kuneta kana kunzwa kuneta zvisingaite kwemazuva 1-2
• Nyonganyonga kana kusagadzikana mudumbu
• Kurwadziwa kwemhasuru kana kusagadzikana mumajoini
• Fivha shoma inowanzo pera nekukurumidza

Izvi zvinowanzoitika zvinowanzoitika kwenguva pfupi uye hazvidi kurapwa kunze kwekuzorora uye matanho ekunyaradza.

Zvimwe zvinokuvadza asi zvisingawanzoitiki zvinogona kuitika, uye chikwata chako chekurapa chichakutarisa zvakanyanya izvi:

• Kusagadzikana kwakanyanya kwemuviri kusanganisira kuoma kufema, kuzvimba kwechiso kana pahuro, kana kuputika kwakapararira
• Kusagadzikana kwakakosha kwekuiswa kwemushonga ne fivha yakanyanya, kutonhora, kana shanduko yeropa
• Kubuda ropa kusingaite kana kupwanya kusingaperi nekukurumidza
• Kurwadziwa kwemusoro kwakanyanya nekuchinja kwekuona
• Zviratidzo zvehutachiona zvinomuka mazuva mushure mekurapwa

Chikwata chekurapa chiri kupa kurapwa kwako chakadzidziswa kuziva nekugadzirisa izvi zvinogumbura nekukurumidza, ndosaka raxibacumab ichipiwa chete munzvimbo dzakakosha dzekutarisira hutano.

Ndiani Asingafaniri Kutora Raxibacumab?

Vanhu vashoma vanogona kusagamuchira raxibacumab pavanenge vachisangana neanthrax, sezvo hutachiona pachahwo huchipa njodzi huru kupfuura mushonga. Zvisinei, mamiriro akati wandei anoda kufungwa kwakakosha uye kutarisa.

Chikwata chako chehutano chichanyatso kuyera njodzi nemabhenefiti kana uine chero mamiriro aya:

• Kuziva kusawirirana kwakanyanya nemishonga ye monoclonal antibodies kana mishonga yakafanana
• Kuzvitakura kwazvino, kunyangwe mushonga ungapiwe kana mabhenefiti achikunda njodzi
• Kutadza kwakanyanya kweitsvo kana chiropa kunokanganisa maitiro emuviri wako ekugadzirisa mishonga
• Mamiriro ezvinhu e autoimmune ari kushanda anogona kukanganiswa nekuchinja kwemaitiro emuviri ekudzivirira zvirwere
• Kubaiwa kwemajekiseni achangobva kuitwa nemajekiseni mhenyu mumavhiki mashoma apfuura
• Kurapa kwazvino nemishonga inoderedza ropa kana mishonga inokanganisa kuumbwa kweropa

Kunyangwe nemamiriro ezvinhu aya, vanachiremba vanowanzoenderera mberi nekurapa raxibacumab nekuti anthrax isina kurapwa inowanzoita njodzi kupfuura njodzi dzemushonga. Chikwata chako chekurapa chichachinja kuongorora nekuchengetedza zvichienderana nemamiriro ako ega.

Mazita eBrand eRaxibacumab

Raxibacumab inotengeswa pasi pezita rebrand Raxibacumab for Injection. Kusiyana nemishonga yakawanda, mushonga uyu hauna mazita akawanda ebrand nekuti unogadzirwa nekambani imwe chete yekushandiswa kwemamiriro ekukurumidza.

Mishonga iyi inopihwa seupfu hwakachena hunofanirwa kugadzirwazve uye kuderedzwa isati yapiwa. Izvi zvinovimbisa kugadzikana uye simba kana mushonga uchidiwa pakurapa kwemamiriro ekukurumidza.

Sezvo raxibacumab iri chikamu cheStrategic National Stockpile muUnited States, inowanikwa zvakanyanya kuburikidza nemasangano ehutano ehurumende panguva yekukurumidza kwehutano hweveruzhinji panzvimbo yekuburikidza nemachannel epharmacy enguva dzose.

Zvimwe zvingashandiswa panzvimbo peRaxibacumab

Kune zvishoma zvingashandiswa panzvimbo pe raxibacumab pakurapa anthrax toxin exposure, ndosaka mushonga uyu wakakosha mukugadzirira mamiriro ekukurumidza. Zvisinei, dzimwe nzira dzinogona kushandiswa pamwe chete kana panzvimbo pe raxibacumab mumamiriro ezvinhu akati wandei.

Kurapa kukuru kunosanganisira:

• Anthrax Immune Globulin (AIG), iyo inopa ma antibodies kubva kuvanhu vakabaiwa anthrax
• Kurapa kwakanyanya kwe antibiotic chete, kunyangwe izvi zvisingashande kana ma toxins atanga kutenderera
• Kuchengetwa kunotsigira nekufema kwemuchina uye kutsigira nhengo dzemuviri mumatambudziko akakomba
• Kurapa kwe experimental kunogona kuwanikwa kuburikidza ne compassionate use programs

Sarudzo pakati pezvisarudzo izvi zvinoenderana nekuwanikwa, nguva yekurapa, uye mamiriro ako ehutano. Muzviitiko zvakawanda, raxibacumab inosarudzwa kana ichiwanika nekuda kweiyo chaiyo nzira yekuita inopesana ne anthrax toxins.

Raxibacumab iri nani pane Anthrax Immune Globulin here?

Raxibacumab uye Anthrax Immune Globulin (AIG) zvese zvinoshanda pakurapa anthrax, asi zvinoshanda kuburikidza nemaitiro akasiyana. Kuenzanisa zvakananga kwakaoma nekuti anowanzo shandiswa mumamiriro akasiyana.

Raxibacumab inopa zvakanakira zvakawanda pamusoro pe AIG. Iri mushonga wakagadzirwa zvakanaka uyo unotarisa anthrax toxin zvakananga, zvichigona kupa simba rakawanda uye mashoma mativi emuviri pane AIG, iyo inobva kuvanhu vanopa.

AIG, zvisinei, yakashandiswa zvakabudirira mumatambudziko chaiwo e anthrax uye inopa huwandu hwakawanda hwema antibodies. Vamwe nyanzvi dzezvekurapa vanosarudza AIG kana ichiwanika nekuti inomiririra mhinduro yekudzivirira muviri yevanhu vakabaiwa anthrax zvakabudirira.

Mukuita, sarudzo inowanzoenderana nezviri kuwanikwa panguva yekurapa. Mishonga yese miviri inogona kuponesa hupenyu, uye kugamuchira imwe yacho nekukurumidza kwakakosha kupfuura kumirira sarudzo chaiyo.

Mibvunzo Inowanzo Bvunzwa Nezve Raxibacumab

Raxibacumab yakachengeteka kuvakadzi vane pamuviri here?

Raxibacumab inogona kupiwa kuvakadzi vane pamuviri kana mabhenefiti achikunda njodzi, izvo zvinowanzoitika kana munhu akabatwa neanthrax. Zvidzidzo zvemhuka hazvina kuratidza mhedzisiro inokuvadza pavana vari kukura, asi data rekuzvitakura kwevanhu rakaganhurirwa.

Kana iwe une pamuviri uye wakabatwa neanthrax, timu yako yezvokurapa ichanyatso funga nezvenguva yekuzvitakura kwako uye kuoma kwekurwara. Anthrax isina kurapwa inounza njodzi huru kwauri nemwana wako, kazhinji ichiita kuti kurapwa ne raxibacumab ive sarudzo yakachengeteka.

Vanachiremba vako vachapa imwe monitoring panguva uye mushure mekurapa kuti vave nechokwadi chekuti iwe nemwana wako munoramba muri vapenyu. Vanogona zvakare kubatana nenyanzvi dzekuzvitakura kuti vakwanise kutarisirwa kwako.

Ndoita Sei Kana Ndikawana Raxibacumab Yakawandisa Netsaona?

Kupfuura muyero netsaona ne raxibacumab hazviite zvakanyanya nekuti mushonga unongopiwa munzvimbo dzakadzorwa dzekurapa nevashandi vakadzidziswa. Dosing inoverengwa zvakanyatsoenderana nehuremu hwako uye inopiwa zvishoma nezvishoma kwemaawa anopfuura maviri.

Kana iwe nenzira yakati wani wakawana yakawanda kupfuura muyero waunofanira kuwana, timu yako yezvokurapa ingawedzera monitoring yezvinhu zvinokonzeresa uye inopa rutsigiro rwekutarisira sezvinodiwa. Hapana mushonga chaiwo we raxibacumab, asi mhedzisiro yakawanda yekupfuura muyero inogona kubatwa nekutarisirwa kwekurapa kwakajairika.

Kugadzirwa kwemushonga kunoita kuti zvive zvakachengeteka kunyangwe pamadosi akakwirisa, kunyangwe kuwedzera monitoring yezvinhu zvinokonzeresa allergic reactions nemamwe mhedzisiro yaizodiwa.

Ndoita Sei Kana Ndikakanganwa Dose ye Raxibacumab?

Kukanganwa dose ye raxibacumab kazhinji hakusi kunetsekana nekuti inowanzo kupiwa seimwe chete kurapwa mumamiriro ezvinhu ekukurumidzira. Kana iwe uchifanira kuwana dose yechipiri sechikamu chechirongwa chako chekurapa, taura nechikwata chako chekurapa nekukasira.

Nguva yekurapa anthrax yakakosha, saka kunonoka kupi nekupi kunofanira kukurukurwa nevanoona nezvehutano vako nekukasira. Vanogona kuona kana uchiri kuda mushonga kana kana chirongwa chako chekurapa chichifanira kuchinjwa.

Usayedze kugadzirisa mushonga wakarasika wega. Raxibacumab inoda kutarisirwa kwechiremba uye inogona kungopihwa munzvimbo dzakakodzera dzekutarisira hutano.

Ndingamira Rini Kutora Raxibacumab?

Hauwanzo "kumira" kutora raxibacumab nekuti inowanzo kupihwa semushonga mumwe chete kana nzira pfupi yekurapa. Mushonga uyu unoenderera mberi uchishanda mumuviri wako kwemavhiki akati wandei mushure mekutarisirwa.

Chikwata chako chekurapa chichakutarisa kwemavhiki mushure mekutambira raxibacumab kuti uve nechokwadi chekuti kurapwa kuri kushanda uye kuti utarise chero mhedzisiro yakazara. Unogona kuva nemisangano yekutevera uye bvunzo dzekurabhoritari kuti utarise kupora kwako.

Kana iwe wakagamuchira raxibacumab yekudzivirira mushure mekuratidzwa, ungangoda kuenderera mberi uchitora maantibayoti kwemavhiki akati wandei kunyangwe mushure mekunge kurapwa kwe raxibacumab kwapera. Vanachiremba vako vachapa mirairo yakajeka nezve zvese zvekutarisirwa kwako kuri kuenderera mberi.

Ndingagamuchira Majekiseni Mushure meRaxibacumab Kurapa?

Unogona kazhinji kugamuchira majekiseni mazhinji mushure mekurapwa kwe raxibacumab, asi nguva uye rudzi rwejekiseni zvinokosha. Chikwata chako chekurapa chichakupa zano panguva yakanakisa yekujekisisa zvichienderana nemamiriro ako ega.

Majekiseni mhenyu anogona kunge achida kunonoka kwemavhiki akati wandei mushure mekurapwa kwe raxibacumab nekuti mushonga unogona kukanganisa mhinduro yako yekudzivirira majekiseni aya. Majekiseni asina simba anowanzo chengeteka kugamuchira nekukurumidza.

Kana iwe wakaratidzwa ku anthrax uye ukagamuchira raxibacumab, unogonawo kupihwa jekiseni re anthrax sechikamu chekutarisirwa kwako mushure mekuratidzwa. Izvi zvinobatsira kupa dziviriro yenguva refu kubva mukuratidzwa kwemangwana.