Chii chinonzi Remimazolam: Zvinoshandiswa, Mishonga, Mativi eMuviri uye Zvimwe

Remimazolam mushonga unokurumidza kushanda wekudzikamisa uyo vanachiremba vanoshandisa panguva yezvinhu zvekurapa kuti vakubatsire kuzorora uye kugara wakadzikama. Iwo wekirasi yemishonga inonzi benzodiazepines, iyo inoshanda nekuderedza basa rehuropi kuti igadzire runyararo, mamiriro ekurara.

Mushonga uyu unopiwa kuburikidza neIV (intravenous) mutsetse zvakananga muropa rako. Chinoita kuti remimazolam ive yakakosha ndeyekuti inoshanda nekukurumidza sei uye nekukurumidza sei muviri wako unoiisa pachena, zvichiita kuti ive yakanakira maitiro mapfupi apo iwe unofanirwa kumuka uchinzwa wakajeka.

Chii chinonzi Remimazolam?

Remimazolam imhando itsva ye benzodiazepine yakagadzirirwa kunyanya sedation yekurapa. Kusiyana nemamwe ma sedatives ekare anogona kugara mumuviri wako kwemaawa, mushonga uyu unoputsika nekukurumidza mumuviri wako kuburikidza nemaitiro echisikigo.

Mishonga inoshanda nekuwedzera kemikari yehuropi inonzi GABA, iyo inoita semuviri wako wechisikigo "kudzikama" chiratidzo. Kana remimazolam ichisimudzira chiratidzo ichi, inogadzira manzwiro akazorora, akarara ayo anokubatsira kuti upfuure maitiro ekurapa zvakanaka.

Vapi vehutano vanosarudza remimazolam nekuti inovapa kutonga kwakaringana pamusoro pehuwandu hwako hwe sedation. Vanogona kugadzirisa muyero zviri nyore uye vanotarisira kuti umuke nekukurumidza kana maitiro apera.

Chii chinonzi Remimazolam chinoshandiswa?

Vanachiremba vanoshandisa remimazolam kunyanya kune procedural sedation panguva yezvinhu zvekurapa zvinoda kuti uzorore asi kwete kusaziva zvachose. Inowanzo shandiswa kune maitiro ekuongorora senge colonoscopies, endoscopies, uye mamwe maitiro ekuvhiya.

Mushonga uyu unobatsira zvakanyanya kune maitiro ekunze kwaunoda kuenda kumba zuva rimwe chete. Nekuti inobviswa mumuviri wako nekukurumidza, haunganyanyi kunzwa uchinetseka kana kuvhiringidzika kwemaawa mushure mekuita kwako.

Zvimwe zvipatara zvinoshandisawo remimazolam mumayuniti ekuchengeta zvakanyanya (ICU) kune varwere vanoda kurara kwenguva pfupi vachishandisa michina yekufema. Nguva yekukurumidza kupora inoita kuti zvive nyore kuti vanachiremba vaongorore kuti varwere vari sei.

Remimazolam Inoshanda Sei?

Remimazolam inoonekwa semushonga wepakati-kati unoshanda nekunangana nemareceptors chaiwo muuropi hwako. Inowedzera mhedzisiro yeGABA, neurotransmitter inononoka basa reuropi uye inosimudzira kuzorora.

Kana mushonga wapinda muropa rako, unosvika muuropi hwako mukati memaminitsi. Mhedzisiro yekuzorodza inowanzo kutanga mukati me1-3 maminitsi ekutonga, zvichikonzera kuti unzwe uine hope uye wakasununguka usingarasikirwi zvachose nekuziva.

Chinonyanya kusiyanisa remimazolam ndeyekuti muviri wako unoishandisa sei. Maenzayemu akakosha anoputsa mushonga nekukurumidza, kazhinji mukati me30-60 maminitsi. Kuparara uku nekukurumidza kunoreva mhedzisiro shoma inogara ichienzaniswa nemamwe ma sedatives anogona kukonzera kuti unzwe wakaremara kwemaawa.

Ndingatora Sei Remimazolam?

Hauzozvitore remimazolam iwe pachako - inogara ichipiwa nevashandi vehutano vakadzidziswa munzvimbo yekurapa. Mushonga uyu unouya semvura yakajeka inosanganiswa nemvura yemunyu uye inopiwa kuburikidza nemutsara weIV muruoko rwako.

Usati waita maitiro ako, chikwata chako chekurapa chichaisa chubhu diki yepurasitiki (IV catheter) mutsinga muruoko rwako kana ruoko. Vachabva vanyatsojekesa remimazolam kuburikidza nemutsara uyu vachitarisa kufema kwako, kumhanya kwemoyo, uye kudzvinyirirwa kweropa.

Chiremba wako achagadzirisa chiyero zvichienderana nezera rako, uremu, nhoroondo yako yekurapa, uye maitiro ako kumushonga. Vanhu vazhinji vanoda huwandu hudiki - kazhinji milligrams shoma - kuti vawane chiyero chakakodzera chekurara.

Unofanirwa kudzivisa kudya kana kunwa kwemaawa akati wandei usati waita maitiro ako, sezvakaratidzwa nechikwata chako chekurapa. Iyi nguva yekutsanya inobatsira kudzivirira matambudziko uye inovimbisa kuti mushonga unoshanda nemazvo.

Ndingatora Remimazolam Kwenguva Yakareba Sei?

Remimazolam rinoshandiswa chete kwenguva pfupi panguva yezvipatara, kazhinji richigara chero kubva pamaminitsi gumi nemashanu kusvika kumaawa mashoma. Kureba kunoenderana zvachose nekuti maitiro ako chaiwo anotora nguva yakareba sei kuti apedzwe.

Mupi wako wehutano achaenderera mberi nekukupa zvidimbu zvidiki panguva yese yekuita sezvinodiwa kuti uchengetedze chiyero chako chekunyaradzwa. Vachamisa mushonga kana maitiro apedzwa, uye iwe uchavhura mukati memaminitsi.

Kusiyana nemishonga yaunotora kumba, remimazolam haina kuitirwa kushandiswa kwenguva refu. Nguva imwe neimwe yaunoda sedation yekuita, timu yako yezvipatara ichaiona seyakatanga itsva, ichigadzirisa muyero zvichienderana nemamiriro ako ehutano azvino.

Ndezvipi Zvipingamupinyi zveRemimazolam?

Semishonga yese, remimazolam inogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachizvitsungirira zvakanaka kana vakapihwa nevapi vehutano vane ruzivo. Mhedzisiro yakajairika chikamu chekuti mushonga unoshanda sei - kurara uye kusavapo kwenguva pfupi kweyeuchidzo kutenderedza maitiro.

Heano mhedzisiro yakajairika yaungangove nayo:

• Kurara kunogona kugara 1-2 maawa mushure mekuita
• Kurasikirwa kweyeuchidzo kwenguva pfupi kutenderedza nguva yekuita
• Dizziness yakapfava kana kunzwa kusagadzikana
• Nausea kana dumbu rakatsamwa
• Musoro
• Kunzwa kuvhiringidzika kana kusagadzikana paunenge uchitanga kumuka

Mhedzisiro iyi inowanzoita nyoro uye inogadzirisa yega sezvo mushonga uchibuda mumuviri wako. Kuva nemumwe munhu anokutyaira kumba uye kugara newe kwemaawa mashoma kunobatsira kuona kuchengeteka kwako panguva yekupora.

Mhedzisiro yakakomba haisi kazhinji asi inogona kusanganisira matambudziko ekufema, shanduko yeropa, kana maitiro ekugadzirisa. Chikwata chako chekurapa chinokutarisa zvakanyanya panguva uye mushure mekuita kuti utarise chero zviratidzo zvinonetsa.

Muzviitiko zvisingawanzoitiki, vamwe vanhu vanogona kusangana nekupinduka kwemaitiro uko vanova nemafungiro kana kushushikana panzvimbo yekunyarara. Kana izvi zvikaitika, chiremba wako anogona kukurumidza kubvisa mhedzisiro nemumwe mushonga.

Ndiani Asingafaniri Kutora Remimazolam?

Remimazolam haikodzeri munhu wese, uye timu yako yezvokurapa ichanyatsoongorora nhoroondo yako yehutano usati washandisa mushonga uyu. Vanhu vane matambudziko ekufema akakomba, mamwe mamiriro emoyo, kana kuziva allergies kune benzodiazepines vanowanzo shandisa dzimwe nzira dzekuzorodza.

Chiremba wako achanyatso chenjerera kana uine chero mamiriro aya:

• Chirwere chemapapu chakakomba kana matambudziko ekufema
• Sleep apnea isina kunyatso kutarisirwa
• Chirwere chechiropa kana itsvo chakakomba
• Nhoroondo yekushandisa zvinodhaka kana doro
• Myasthenia gravis (chirwere chetsandanyama)
• Matambudziko emoyo akakomba
• Kuziva allergy kune benzodiazepines

Vakadzi vane pamuviri nevamwe vanoyamwisa vanoda kutariswa zvakakosha, sezvo mushonga unogona kuyambuka placenta uye kuoneka mumukaka wemazamu. Chiremba wako achayera mabhenefiti achipesana nenjodzi dzinogona kuitika mumamiriro ezvinhu aya.

Vanhu vakuru vanogona kunge vachinyanya kunzwisisa mhedzisiro ye remimazolam uye vanowanzo gamuchira madosi akaderera. Mushonga unogonawo kuita nemimwe mishonga, saka ita shuwa kuti unoudza timu yako yezvokurapa nezve mishonga yese, zvinowedzera, uye mishonga yemakwenzi yaunotora.

Remimazolam Mazita eBrand

Remimazolam inowanikwa pasi pezita rebrand Byfavo muUnited States nedzimwe nyika. Iri ndiro zita rekutanga rebrand raunosangana naro munzvimbo zhinji dzekurapa.

Mune dzimwe nzvimbo, unogona kuona ichitengeswa pasi pemazita akasiyana, asi chinhu chinoshanda chinoramba chakafanana. Chiremba wako achaziva mushonga nezita rake re generic (remimazolam) zvisinei nezita rebrand rinoshandiswa panzvimbo yavo.

Sezvo iyi iri mushonga mutsva, wakabvumidzwa neFDA muna 2020, hapana mhando dzemajenari dziripo. Remimazolam yese parizvino inobva kumugadziri wekutanga.

Zvimwe Zvinhu Zvokutsiva Remimazolam

Kana remimazolam isiri yakanaka kwauri, dzimwe nzira dzakawanda dzokuzorodza nadzo dziripo zvichienderana nezvido zvako zvakakosha uye nhoroondo yako yezvokurapa. Murapi wako wezvehutano anogona kusarudza kubva kune dzimwe nzira dzakasiyana dzinotora nzira dzakasiyana asi dzinowana mhedzisiro yakafanana.

Zvimwe zvinhu zvakajairika zvinosanganisira:

• Midazolam - imwe benzodiazepine yakashandiswa kwemakumi emakore
• Propofol - imwe mhando yekuzorodza inoshanda nekukurumidza
• Dexmedetomidine - mushonga unopa kuzorodzwa usingakanganisi kufema zvakanyanya
• Ketamine - dzimwe nguva inoshandiswa kune nzira dzinoda kuzorodzwa kwakadzama
• Nitrous oxide - "gasi rekuseka" rekuzorodzwa kwakareruka

Imwe neimwe nzira ine mabhenefiti ayo uye zvinhu zvokufunga nezvazvo. Anesthesiologist wako kana timu yenzira ichasarudza sarudzo yakanakisisa zvichienderana nenhoroondo yako yezvokurapa, mhando yenzira, uye kuti inotarisirwa kutora nguva yakareba sei.

Sarudzo iyi inowanzoenderana nezvinhu zvakaita sezera rako, mamwe mishonga yaunotora, uye kana uine chero mamiriro ehutano ari pasi anoita kuti imwe sarudzo ive yakachengeteka kune vamwe.

Ko Remimazolam Ari Nani Kupfuura Midazolam?

Remimazolam na midazolam zvose zviri benzodiazepines zvinoshandiswa pakuzorodzwa, asi zvine misiyano yakakosha inoita kuti imwe neimwe ive yakakodzera mamiriro akasiyana. Hapana kana imwe iri "iri nani" zvachose - zvinoenderana nezvido zvako zvakakosha uye mamiriro ako.

Chinhu chikuru chinobatsira Remimazolam ndiyo nguva yayo yekupora inotarisirwa, nekukurumidza. Nekuti muviri wako unoiisa pasi nekukurumidza kuburikidza nemaitiro echisikigo e-enzyme, unogona kunzwa uchinyanya kuziva nekukurumidza mushure mekuita kwako zvichienzaniswa ne midazolam.

Midazolam yakashandiswa zvakachengeteka kwemakumi emakore uye inowanzoita isingadhuri. Zvisinei, inogona kuunganidza mumuviri wako, kunyanya kana wakura kana uine matambudziko echiropa, zvichikonzera nguva refu yekupora uye kurara kwenguva refu.

Kune nzira dzekurapa dzekunze dzaunoda kuenda kumba zuva rimwe chete, kubviswa nekukurumidza kwe remimazolam kunogona kuve mukana wakakura. Kune nzira refu kana mutengo uri chinhu chikuru, midazolam inogona kuve sarudzo iri nani.

Mibvunzo Inowanzo Bvunzwa Nezve Remimazolam

Remimazolam Yakachengeteka Here Kune Vanhu vane Chirwere Chemoyo?

Remimazolam inogona kushandiswa zvakachengeteka muvanhu vazhinji vane chirwere chemoyo, asi chiremba wako wemoyo uye timu yeanesthesia vachada kushanda pamwechete kuti vave nechokwadi chekuti ndiyo sarudzo yakakunakira. Mushonga uyu unowanzoita shanduko shoma mumuviri mukuenzanisa nedzimwe sedatives.

Timu yako yezvokurapa ichatarisa rhythm yemoyo wako uye BP nguva dzose panguva yechirongwa. Vachatarisawo mamiriro ako chaiwo emoyo, mishonga iripo, uye hutano hwese usati waenderera mberi vachisarudza kana remimazolam yakakodzera.

Vanhu vane kukundikana kwemoyo kwakanyanya kana rhythm yemoyo isina kugadzikana vangangoda dzimwe nzira dzekurapa. Vapi vehutano vachagara vachisarudza sarudzo yakachengeteka yemamiriro ako ega.

Ndingaita Sei Kana Ndikagamuchira Zvakawandisa Remimazolam Netsaona?

Haufanire kunetseka nezve kugamuchira zvakawandisa remimazolam netsaona nekuti nyanzvi dzehutano dzakadzidziswa dzinodzora zvese zvekupa mishonga yako. Vanotarisa mhinduro yako nguva dzose uye vanogadzirisa muyero sezvinodiwa panguva yechirongwa chako.

Kana iwe wakagamuchira zvakawanda kupfuura zvaitarisirwa, timu yako yezvokurapa ine nzira dzakawanda dzekukubatsira kupora zvakachengeteka. Vanogona kukupa mushonga unonzi flumazenil uyo unokurumidza kubvisa mhedzisiro ye remimazolam, kukubatsira kumuka nekukurumidza.

Vapi vako vezvehutano vakadzidziswa kuziva zviratidzo zvekunyanyisa kunyorerwa uye vanopindura nekukasira. Vachatsigira kufema kwako kana zvichidikanwa uye vachatarisa zviratidzo zvako zvakakosha zvakanyanya kusvika waziva zvizere uye wakamira zvakanaka.

Ndingaita Sei Kana Ndakarasikirwa neDose yeRemimazolam?

Mubvunzo uyu haushande kune remimazolam nekuti haisi mushonga waunotora kumba pane chirongwa. Vashandi vehutano vanongopa remimazolam panguva yezvinhu zvekurapa munzvimbo dzekurapa dzakadzorwa.

Kana uine maitiro akarongeka anoda kunyorerwa uye ukakanganwa kugadzwa kwako, uchafanirwa kuronga zvakare nemupi wako wehutano. Vachakupa mushonga mutsva panguva yezvawakarongeka zvakare.

Nguva imwe neimwe yaunoda kunyorerwa, timu yako yekurapa inoiona semamiriro matsva, ichinyatsoongorora hutano hwako hwazvino uye ichigadzirisa mushonga zvinoenderana.

Ndingamira Rini Kutora Remimazolam?

Haufanire kuita chero zvisarudzo zvekumisa remimazolam nekuti timu yako yehutano inodzora kana kutanga uye kumisa mushonga panguva yezvawaita. Vachamisa kana maitiro ako apera.

Mushonga uyu unozobviswa kubva muhurongwa hwako mukati memaminitsi makumi matatu kusvika makumi matanhatu mushure mekunge mupi wako wehutano amira kukupa. Zvishoma nezvishoma uchava akangwarira sezvo mushonga uchibva mumuviri wako.

Kupora kwako kunotungamirirwa nechikwata chako chekurapa, icho chichakutarisa kusvikira waziva zvakakwana kuti uende kumba zvakachengeteka. Vachakuzivisa kana wagadzirira kuenda uye zvaunotarisira panguva yekupora kwako kumba.

Ndingatyaira Here Mushure meKugamuchira Remimazolam?

Haufanire kutyaira kana kushandisa michina kwemaawa makumi maviri nemana mushure mekutambira remimazolam, kunyangwe iwe uchigona kunzwa wakangwarira nekukurumidza. Mushonga uyu unogona kukanganisa nguva yako yekupindura uye kutonga nenzira dzakapfava dzaungasaziva.

Rongedza kuti mumwe munhu akuendesere kumba mushure mekuvhiwa kwako uye agare newe kwemaawa akati wandei. Izvi hazvisi kungo chengetedza - izvi zvinodiwa zvekuchengetedza izvo nzvimbo zhinji dzemishonga dzichaita usati wabvumidzwa kuenda.

Kunyangwe iwe uchinzwa zvakajairika zvachose, uropi hwako huchiri kugadzirisa mhedzisiro yemishonga. Zviitiko zvinoda kuratidza nekukurumidza kana kuita zvisarudzo zvakakosha zvinofanirwa kumirira kusvika mangwana paunenge wadzokera zvizere kune yako yekutanga.