Chii chinonzi Rifampin ne Isoniazid: Zvinoshandiswa, Madosi, Matambudziko, nezvimwe

Rifampin ne isoniazid mushonga unosanganisa unorwisa zvirwere zve tuberculosis (TB). Mabhakitiriya maviri aya ane simba anoshanda pamwechete kuuraya mabhakitiriya anokonzera TB, zvichiita kuti kurapwa kushande zvakanyanya pane kushandisa mushonga mumwe chete.

Kurapa uku kwave kuri dombo rekutanga rekurapa TB kwemakumi emakore. Chiremba wako anokuraira nekuti mabhakitiriya eTB akanyanya kuoma uye anoda mishonga yakawanda kudzivirira kuti asadzivise kurapwa.

Chii chinonzi Rifampin ne Isoniazid?

Rifampin ne isoniazid inosanganisa mishonga miviri inorwisa TB mupiritsi rimwe chete riri nyore. Rifampin ndeyeboka remishonga inorwisa mabhakitiriya inonzi rifamycins, nepo isoniazid iri chikamu chemhuri ye hydrazide yemishonga inorwisa TB.

Pamwechete, mishonga iyi inogadzira simba rimwe-mbiri rinorwisa mabhakitiriya eTB. Rifampin inokanganisa kugona kwemabhakitiriya kugadzira mapuroteni akakosha, nepo isoniazid ichivadzivisa kuvaka masvingo avo ekudzivirira masero.

Mubatanidzwa uyu unouya muchimiro chepiritsi uye unowanzo torwa kamwe chete pazuva. Mushonga uyu unowanikwa mumasimba akasiyana kuti uenderane nezvido zvako zvekurapa zvinoenderana nehuremu hwako uye kuoma kwehutachiona hwako.

Chii chinoshandiswa Rifampin ne Isoniazid?

Mishonga iyi inosanganisa inorapa zvirwere zve tuberculosis zvinoshanda uye inobatsira kudzivirira TB muvanhu vakabatwa nemabhakitiriya. Chiremba wako anogona kukuraira kana uine chirwere cheTB chinokanganisa mapapu ako, ma lymph nodes, kana dzimwe nhengo dzemuviri wako.

Mushonga uyu unoshanda zvakanyanya pakurapa pulmonary TB, iyo inokanganisa mapapu uye ndiyo mhando yakajairika yechirwere. Inogonawo kurapa extrapulmonary TB, iyo inoitika kana hutachiona huchipararira kupfuura mapapu kune dzimwe nhengo.

Dzimwe nguva vanachiremba vanonyora musanganiswa uyu wechirwere cheTB chakavanda, uko kwaunenge wakabata mabhakitiriya asi usati wanzwa kurwara. Kurapa TB yakavanda kunodzivirira kuti isazove chirwere chinoshanda gare gare muhupenyu.

Mupi wako wehutano angakurudzirawo mushonga uyu kana wanga uri pedyo nemunhu ane TB inoshanda, kunyanya kana uine njodzi dzinokuita kuti uwane chirwere ichi.

Rifampin neIsoniazid Zvinoshanda Sei?

Musanganiswa uyu unoshanda nekutambudza mabhakitiriya eTB kuburikidza nenzira mbiri dzakasiyana, zvichiita kuti zvive zvakaoma kuti utachiona hupone uye huwedzere. Rifampin inovhara enzyme inonzi RNA polymerase iyo mabhakitiriya eTB anoda kuti agadzire mapurotini akakosha kuti ararame.

Isoniazid inotarisa chikamu chakasiyana chehurongwa hwekurarama hwebhakitiriya nekudzivirira kuti vasagadzire mycolic acid, chikamu chakakosha chemadziro avo esero. Pasina madziro akasimba esero, mabhakitiriya anova asina simba uye anozofa.

Kushandisa mishonga yese iri miviri pamwe chete kunogadzira izvo vanachiremba vanoti

Kana uine dumbu rinokunetsa, unogona kutora mushonga uyu uine chikafu chidiki, asi izvi zvinogona kuderedza kushanda kwemushonga. Vamwe vanhu vanowana kuti kutora mushonga uyu nemakareka kana tosti kunobatsira kuderedza kusvotwa.

Edza kutora mushonga wako panguva imwe chete zuva rega rega kuti uchengetedze mazinga akagadzikana muropa rako. Kugadza alarm yezuva nezuva kunogona kukubatsira kuyeuka, kunyanya nekuti kurapwa kweTB kunoda kushandiswa kwemishonga nguva dzose kwemwedzi yakati wandei.

Dzivisa doro paunenge uchitora mushonga uyu, nekuti rifampin ne isoniazid zvinogona kukanganisa chiropa chako, uye doro rinowedzera njodzi iyi. Chiremba wako anogona kutarisa kushanda kwechiropa chako nekuyedzwa kweropa nguva dzose.

Ndingatora Rifampin ne Isoniazid Kwenguva Yakareba Sei?

Vanhu vazhinji vanotora musanganiswa uyu kwemwedzi mitanhatu kusvika kumapfumbamwe, zvichienderana nerudzi uye kuoma kwehutachiona hwavo hweTB. Chiremba wako achasarudza nguva chaiyo zvichienderana nemamiriro ako chaiwo uye kuti unopindura sei kurapwa.

YeTB inoshanda yemumapapu, nzira yekurapa inowanzoitwa ndeyemwedzi mitanhatu, nepo extrapulmonary TB inogona kuda kurapwa kwenguva refu. Vanhu vane TB inodzivisa mishonga kana immune system dzakakanganiswa vangangoda kurapwa kwakawedzerwa.

Zvakakosha kupedzisa nzira yese yekurapa, kunyangwe ukatanga kunzwa zviri nani mushure memavhiki mashoma. Kumira nekukurumidza kunogona kubvumira mabhakitiriya anopona kuti awande uye anogona kukudziridza kuramba mishonga.

Chiremba wako achatarisa kufambira mberi kwako nekutarisa nguva dzose uye anogona kugadzirisa nguva yekurapa zvichienderana nekuti hutachiona hunopindura sei. Vamwe vanhu vangangoda mamwe mwedzi ekurapa kana TB yavo ichinyanya kuoma.

Ndezvipi Zvakaipa zveRifampin ne Isoniazid?

Semishonga yese, rifampin ne isoniazid zvinogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachizvitsungirira zvakanaka. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakagadzirira uye uzive kuti ungataurirana riini nemupi wako wehutano.

Zvakawanda zvinokonzeresa matambudziko zvinowanzoita zvishoma uye zvinowanzoita nani muviri wako paunojaira mushonga. Hezvino zvinokonzeresa zvaungangove uine:

• Ruvara rweorenji kana tsvuku rweweti yako, misodzi, mate, uye ziya
• Kunyara zvishoma kana dumbu risinganzwe zvakanaka
• Kurasikirwa nechido
• Musoro unovava zvishoma
• Dizziness
• Kuneta kana kunzwa kuneta kupfuura zvakajairika

Ruvara rweorenji rwakajairika uye harukuvadzi, kunyangwe ruchigona kuita kuti malenzi ekubata maziso nemapfekero azare. Ichi chiitiko chichanyangarika paunomira kutora mushonga.

Nepo zvisingawanzoitika, vamwe vanhu vanowana matambudziko akakura anoda kutariswa kwechiremba. Izvi zvinoitika muzvikamu zvidiki zvevarwere asi zvakakosha kuziva:

• Kunyara nekutsvanzika zvisingamire
• Kurwadziwa kwakanyanya mudumbu
• Kusvava kweganda kana maziso (jaundice)
• Weti yeruvara rwerima kupfuura ruvara rweorenji rwaitarisirwa
• Ushoma husina kujairika kana kuneta
• Kusanzwa kana kunzwa kupisa mumaoko kana tsoka
• Fivha isingamire kana zviratidzo zvakaita sefuruwenza

Izvi zviratidzo zvinogona kuratidza matambudziko echiropa kana kukuvadzwa kwetsinga, izvo zvose zviri zvisingawanzoitiki asi matambudziko akakomba anoda kuongororwa kwechiremba nekukasira.

Kazhinji, vamwe vanhu vanogona kuwana maitiro akakomba ekuita allergic kana kukuvadzwa kwakakura kwechiropa. Nepo izvi zvakakomba zvinokanganisa isingasviki 1% yevanhu, zvinoda kutariswa kwechiremba nekukasira kana zvikaonekwa.

Ndiani Asingafaniri Kutora Rifampin uye Isoniazid?

Vamwe vanhu vanofanira kudzivisa iyi mushonga wemubatanidzwa nekuda kwenjodzi dzakawedzera dzematambudziko. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa usati wanyora mushonga uyu.

Vanhu vane chirwere chechiropa chakakomba kana nhoroondo yematambudziko echiropa havafaniri kutora iyi mubatanidzwa, sezvo mishonga yose iri miviri ichigona kukanganisa basa rechiropa. Kana uine hepatitis kana mamwe mamiriro echiropa, chiremba wako anogona kusarudza mamwe marapirwo.

Mushonga uyu haukurudzirwi panguva yekuzvitakura, kunyanya mumwedzi mitatu yekutanga, kunze kwekunge zvakanakira zviri pachena kupfuura njodzi. Kana wakazvitakura kana kuronga kuzvitakura, taura nezve dzimwe nzira dzakachengeteka nachiremba wako.

Vanhu vane nhoroondo yekurwara zvakanyanya kune rifampin kana isoniazid havafaniri kutora musanganiswa uyu. Avo vane mamiriro akati wandei emagene anokanganisa maitiro emuviri ekugadzirisa mishonga iyi vanogonawo kuda dzimwe nzira dzekurapa.

Kana uine chirwere cheitsvo, chirwere cheshuga, kana kutora dzimwe mishonga, chiremba wako angangoda kugadzirisa mushonga wako kana kukutarisa zvakanyanya. Dzimwe nzira dzekudyidzana dzemishonga dzinogona kuva dzakakomba, saka gara uchitaurira chiremba wako nezve mishonga yese yaunotora.

Mazita emhando yeRifampin neIsoniazid

Zita rinowanzozivikanwa remusanganiswa uyu ndiRifamate, iyo inowanikwa zvakanyanya muUnited States. Mhando iyi ine rifampin neisoniazid mumadosi akagadziriswa akagadzirirwa nyore nyore kamwe chete pazuva.

Mune dzimwe nyika, unogona kuwana musanganiswa uyu pasi pemazita akasiyana emhando, kunyangwe zvinhu zvinoshanda zvichiramba zvakafanana. Muzvinemakemikari wako anogona kukubatsira kuziva zvigadzirwa zvakaenzana kana uri kufamba kana uchida kuzadza mishonga munzvimbo dzakasiyana.

Mhando dzakajairika dzemusanganiswa we rifampin ne isoniazid dziripowo uye dzinobatsira zvakanyanya semhando dzemhando. Izvi zvingasarudzwa zvakajairika zvinowanzoita mari shoma uchipa mabhenefiti akafanana ekurapa.

Dzimwe nzira dzeRifampin neIsoniazid

Kana usingakwanise kutora rifampin ne isoniazid, dzimwe nzira dzekurapa dzinogona kurapa zvirwere zveTB. Chiremba wako achasarudza sarudzo yakanakisa zvichienderana nemamiriro ako chaiwo uye nhoroondo yekurapa.

Ethambutol yakasanganiswa nemimwe mishonga yeanti-TB inopa imwe nzira inobatsira kune vanhu vasingakwanise kushivirira rifampin kana isoniazid. Musanganiswa uyu unoshanda zvakasiyana asi unogona kushanda zvakaenzana kune mhando dzakawanda dzeTB.

Kune vanhu vane TB isingaporeswi nemishonga, mishonga mitsva yakaita sebedaquiline kana linezolid inogona kuva inodiwa. Kurapa uku kunowanzo chengeterwa nyaya idzo kurapwa kwakajairika kusina kushanda kana kusina kukodzera.

Vamwe vanhu vangada kutora mishonga yega yega zvakasiyana pane muchimiro chakasanganiswa. Nzira iyi inobvumira kugadzirisa kwakanyatsojeka kwemadosi kana iwe ukawana mhedzisiro kubva kune chimwe chinhu asi kwete kune chimwe.

Ko Rifampin ne Isoniazid Zviri Nani Kupfuura Zvimwe Zvinhu Zvinorapa TB?

Rifampin uye isoniazid musanganiswa wanga uri muyero wegoridhe wekurapa TB kwemakumi emakore nekuda kwekushanda kwayo kwakaratidzwa uye mhedzisiro inodzoreka. Zvidzidzo zvekurapa zvinoratidza nguva dzose mitengo yepamusoro yekupora kana vanhu vapedza nzira yakazara yekurapa.

Kana ichienzaniswa nekutora mishonga yakawanda yakasiyana, musanganiswa uyu unopa nyore nyore mapiritsi mashoma uye zvirongwa zvakareruka zvekupa mishonga. Nyore nyore iyi inowanzoita kuti vanhu vateerere zviri nani, izvo zvakakosha kubudirira kwekurapa TB.

Zvisinei,

Rifampin inogona kukanganisa mishonga ye shuga, kunyanya iyo inogadziriswa nechiropa. Chiremba wako angangoda kugadzirisa mishonga yako yeshuga kana kukutarisa zvakanyanya panguva yekurapa TB.

Kana uine chirwere cheshuga, zivisa chiremba wako usati watanga musanganiswa uyu. Vanogona kukubatsira kugadzira chirongwa chekutarisa kuti uve nechokwadi chekuti kurapwa kwako TB nekutarisirwa kweshuga zvinoramba zviri munzira.

Ndingaita Sei Kana Ndakatora Rifampin ne Isoniazid zvakanyanya netsaona?

Kana netsaona ukatora zvakawanda kupfuura chiyero chawakapiwa, fonera chiremba wako kana nzvimbo yekudzora muchetura nekukasira. Kutora zvakawanda kunogona kuwedzera njodzi yako yemigumisiro yakakomba, kunyanya kukuvadzwa kwechiropa.

Usaedze kuzviita kuti urutse kunze kwekunge wakanzi nevanachiremba. Pane kudaro, inwa mvura yakawanda uye tsvaga rubatsiro rwekurapa nekukasira, kunyanya kana uine kusvotwa kwakanyanya, kurutsa, kana kurwadziwa mudumbu.

Uya nebhodhoro remushonga newe kuimba yekukurumidzira kuti vashandi vezvehutano vagone kuona chaizvo zvawakatora uye zvakawanda sei. Rubatsiro rwekurapa nekukasira runogona kubatsira kudzivirira kana kuderedza matambudziko kubva pakudya zvakanyanya.

Ndingaita Sei Kana Ndikakanganwa Dose ye Rifampin ne Isoniazid?

Kana ukakanganwa dose, itore paunorangarira, kunze kwekunge yava nguva yechiyero chako chinotevera. Muchiitiko ichocho, siya dose yakakanganwa uye uenderere mberi nechirongwa chako chetsika.

Usambofa wakatora zviyero zviviri panguva imwe chete kuti ugadzirise dose yakakanganwa, sezvo izvi zvinogona kuwedzera njodzi yako yemigumisiro. Kana iwe uchikanganwa zviyero kazhinji, funga kumisa maalarm efoni kana kushandisa chirongwa chemushonga kuti zvikubatsire kurangarira.

Kukanganwa zviyero dzimwe nguva hakuzokanganisi kurapwa kwako, asi kuenderana kwakakosha kurapa TB. Kana ukakanganwa zviyero zvinopfuura zvishoma, fonera chiremba wako kuti ukurukure maitiro ekudzoka munzira zvakachengeteka.

Ndingamira Rini Kutora Rifampin ne Isoniazid?

Usambomira kutora mushonga uyu usina kubvumidzwa nachiremba wako, kunyangwe ukanzwa zvakanaka zvachose. Mabhakitiriya eTB anogona kurarama mumuviri mako kwemwedzi, uye kumisa kurapwa nekukurumidza kunogona kukonzera kutadza kurapwa kana kuramba mishonga.

Chiremba wako achasarudza kana zvakachengeteka kumisa zvichibva pamhinduro yako kumishonga, bvunzo dzekutevera, uye rudzi rweTB rwaunaro. Vanhu vazhinji vanoda kupedzisa angangoita mwedzi mitanhatu yekurapwa.

Kana mhedzisiro yezvakaipa ikava isingashiviririki, taura nachiremba wako nezvekugadzirisa kurapwa kwako pane kumira wega. Vanogona kukwanisa kuchinja muyero wako kana kukuchinjira kumishonga imwe nzira vachive nechokwadi chekuti kurapwa kwako TB kunoramba kuchishanda.

Ndinganwa Doro Ndiri Kutora Rifampin uye Isoniazid?

Zvinokurudzirwa zvakasimba kudzivisa doro zvachose uchitora musanganiswa wemishonga iyi. Zvese rifampin uye isoniazid zvinogona kukanganisa chiropa chako, uye doro rinowedzera zvakanyanya njodzi yekukuvadzwa kwakakomba kwechiropa.

Kunyangwe huwandu hudiki hwedoro hunogona kuve hunonetsa kana hwakabatana nemishonga iyi. Njodzi haina kukosha, kunyanya sezvo kurapwa kweTB kazhinji kunotora mwedzi yakati wandei.

Kana uine zvinokunetsa nezvekushandisa doro kana uchida rubatsiro rwekudzivisa doro panguva yekurapwa, kurukura izvi pachena nemupi wako wehutano. Vanogona kupa zviwanikwa uye nzira dzekukubatsira kuti urambe usina doro panguva yekurapwa kwako TB.