Sapropterin (inorapwa nemumuromo)
Mhando dzinowanikwa
Kuvan
Nezve mushonga uyu
Sapropterin inoshandiswa kuderedza phenylalanine muropa revanhu vane phenylketonuria (PKU). Kuwanda kwe phenylalanine (amino acid) muropa kunogona kukonzera kukuvara kwakanyanya kwepfungwa, kusanganisira kushaya pfungwa kwakanyanya, kuita zvikwata, kufamba-famba, kana kuderedza kukwanisa kudzidza. Mushonga uyu kazhinji unopiwa pamwe chete nechikafu chakasarudzika. Mushonga uyu unowanikwa chete nechirongo chakabva kuna chiremba. Chigadzirwa ichi chinowanikwa mumaitiro anotevera ekurapa:
Usati washandisa mushonga uyu
Pakusarudza kushandisa mushonga, njodzi dzekutora mushonga unofanirwa kuyerwa nemabhenefiti awo. Iyi sarudzo iwe nesachiremba wenyu muchaita. Kune mushonga uyu, zvinotevera zvinofanirwa kufungwa: Udza chiremba wako kana iwe wakambonzwa chero mhinduro isingawanzoitika kana chirwere cheallergy kumushonga uyu kana mimwe mishonga. Uyewo udza nyanzvi yako yehutano kana iwe uine mamwe marudzi eallergies, senge zvekudya, dyes, preservatives, kana mhuka. Nezvigadzirwa zvisingadi kuraira, verenga zvinyorwa zvepakiti kana zvinosanganiswa zvakanaka. Ongororo dzakakodzera hadzina kuitwa pane hukama hwezera nemigumisiro yesapropterin muvana vane makore asingasviki mwedzi mumwe chete. Kuvimbika uye kushanda hazvina kusimbiswa.. Ongororo dzakakodzera pane hukama hwezera nemigumisiro yesapropterin hazvina kuitwa muvanhu vakwegura. Kuvimbika uye kushanda hazvina kusimbiswa. Hapana ongororo dzakakwana muvakadzi dzekuona njodzi yemwana pakuita mushonga uyu panguva yekuyamwisa. Yera mabhenefiti anogona kuitika pamwe nenjodzi dzinogona kuitika usati watora mushonga uyu panguva yekuyamwisa. Kunyangwe mimwe mishonga isingafanirwe kushandiswa pamwe chete, mune mamwe mamiriro mishonga miviri yakasiyana inogona kushandiswa pamwe chete kunyangwe kuwirirana kungangoitika. Mumativi aya, chiremba wako angada kuchinja chiyero, kana mamwe matanho angave achidiwa. Paunenge uchitora mushonga uyu, zvakakosha kuti nyanzvi yako yehutano izive kana uri kutora chero mishonga iri pazasi. Kuwirirana kunotevera kwakasarudzwa zvichienderana nechinangwa chavo uye hazvisi zvese zvinosanganisirwa. Kushandisa mushonga uyu nechero mishonga inotevera kazhinji hakusi kukurudzirwa, asi kunogona kudiwa mune zvimwe zviitiko. Kana mishonga yese ikanyorwa pamwe chete, chiremba wako angachinja chiyero kana kuti ungashandisa sei imwe kana ese mishonga. Mimwe mishonga haifaniri kushandiswa panguva yekudya kana pedyo nekurima kana kudya marudzi akati wandei ezvokudya sezvo kuwirirana kungangoitika. Kushandisa doro kana fodya nemimwe mishonga kunogona zvakare kukonzera kuwirirana kuitika. Kurukurai nehutano hwako hwenyanzvi kushandiswa kwemushonga wako nezvokudya, doro, kana fodya. Kuvapo kwemamwe matambudziko ehutano kunogona kukanganisa kushandiswa kwemushonga uyu. Ita shuwa kuti unoudza chiremba wako kana iwe uine mamwe matambudziko ehutano, kunyanya:
Mashandisirwo aungaita mushonga uyu
Tora mushonga uyu chete sezvakarayirwa nachiremba wako. Usatore zvakawanda, usatore kazhinji, uye usatore kwenguva yakareba kupfuura zvakarayirwa nachiremba wako. Kuita izvozvo kunogona kuwedzera mukana wezvinhu zvinokanganisa. Mushonga uyu unofanira kuuya nechiratidzo chemashoko kumurwere. Verenga utevedzere mirairo iyi zvakanyatsonaka. Bvunza chiremba wako kana uine mibvunzo ipi neipi. Zviri nani kutora mushonga uyu nechikafu panguva imwe chete zuva rega rega. Tevedzera zvakanyatsonaka mirairo yechiremba wako nezvekudya kwakasarudzika. Zvakakosha kuti uchengetedze kudya kwakaderera phenylalanine. Varwere vanorema kupfuura makirogiramu gumi vari kushandisa poda yekumwa: Dururira zviri mukati me 100 mg- kana 500 mg-paket mu 4 kusvika ku 8 ounces (1/2 kusvika ku 1 kapu) yemvura kana muto weapuro. Sanganisa zvakanaka. Inwa musanganiswa uyu mukati memaminitsi makumi matatu. Unogona kuwedzerawo mune chikafu chidiki, sekunge applesauce kana pudding usati watora. Varwere vanorema kupfuura makirogiramu gumi vari kushandisa mahwendefa: Unogona kumira mahwendefa ese kana kuasanganisa mu 4 kusvika ku 8 ounces (1/2 kusvika ku 1 kapu) yemvura kana muto weapuro usati watora. Zvinogona kutora maminitsi mashoma kuti mahwendefa anyungudike. Kuti uite kuti mahwendefa anyungudike nekukurumidza, unogona kuasanganisa kana kuapwanya. Inwa musanganiswa uyu mukati memaminitsi gumi nemashanu. Unogona kupwanyawo mahwendefa uye kusanganisa mune chikafu chidiki chinyoro, sekunge applesauce kana pudding usati watora. Doses yemushonga uyu ichave yakasiyana kune varwere vakasiyana. Tevedzera mirairo yechiremba wako kana mirairo iri parineni. Ruzivo runotevera rinosanganisira chete avhareji doses yemushonga uyu. Kana dose yako yakasiyana, usachinje kunze kwekunge chiremba wako akakuudza kuti uite izvozvo. Huwandu hwemushonga waunotora hunotsamira pakusimba kwemushonga. Uyewo, nhamba ye doses yaunotora zuva rega rega, nguva inobvumirwa pakati pe doses, uye nguva yaunotora mushonga zvinoenderana nedambudziko remuviri rauri kushandisa mushonga. Kana ukasapotsa dose yemushonga uyu, itora nekukurumidza sezvinobvira. Nekudaro, kana iri nguva yekutora dose yako inotevera, siya dose yakarasika uye dzoka kune yako dosing schedule yakajairwa. Usatore doses kaviri. Chengetera kure nevana. Usachengetere mushonga wakapfuura zuva rayo kana mushonga usingachadiwi. Bvunza nyanzvi yako yehutano maitiro aunofanira kubvisa mushonga iwo wauri kusashandisa. Chengeta mushonga muhari yakavharwa pane tembiricha yekamuri, kure nekupisa, hunyoro, uye chiedza chakananga. Chengeta kuti urege kuvhunduka. Chengeta bhodhoro rakasimba. Chengeta mushonga mubhodhoro rayo rekutanga rawakapihwa pa pharmacy.