Chii chinonzi Saxagliptin uye Dapagliflozin: Zvinoshandiswa, Mishonga, Migumisiro uye Zvimwe

Saxagliptin uye dapagliflozin mushonga unosanganiswa unobatsira kudzora chirwere cheshuga che mhando 2 nekushanda munzira mbiri dzakasiyana mumuviri wako. Iyi nzira yekushanda kaviri inogona kushanda zvakanyanya pane kushandisa mushonga mumwe chete, ichikupa kutonga kwakanaka kweshuga yeropa nekureruka kwekutora piritsi rimwe chete.

Funga nezvekusanganiswa uku sekuedza kwechikwata mukati memuviri wako. Nepo saxagliptin ichibatsira pancreas yako kugadzira insulin yakawanda paunoida, dapagliflozin inobatsira itsvo dzako kubvisa shuga yakawandisa kuburikidza nemvura yako. Pamwe chete, vanobata shuga yeropa yakakwira kubva kumakona akawanda, izvo zvinowanzoita kuti vanhu vazhinji vave nekudzora kwakanaka kwechirwere cheshuga.

Chii chinonzi Saxagliptin uye Dapagliflozin?

Saxagliptin uye dapagliflozin mushonga unopiwa nachiremba unosanganisa mishonga miviri yakasiyana yechirwere cheshuga mupiritsi rimwe riri nyore. Saxagliptin ndeyeboka rinonzi DPP-4 inhibitors, nepo dapagliflozin iri chikamu cheboka idzva rinozivikanwa seSGLT2 inhibitors.

Chikamu chimwe nechimwe chinoshanda zvakasiyana asi chine chinangwa chimwe chekuderedza mazinga eshuga yeropa rako. Saxagliptin inobatsira muviri wako kugadzira insulin yakawanda kana shuga yeropa rako ikakwira uye inoderedza huwandu hweshuga hunogadzirwa nechiropa chako. Dapagliflozin inotora nzira yakasiyana nekubatsira itsvo dzako kusefa glucose yakawandisa uye kuibvisa kuburikidza nemvura yako.

Iyi musanganiswa yakagadzirirwa zvakananga vanhu vakuru vane chirwere cheshuga che mhando 2 vanoda mishonga inopfuura imwe kuti vawane zvinangwa zvavo zveshuga yeropa. Chiremba wako angakupa mushonga uyu kana kudya, kurovedza muviri, uye mushonga mumwe chete zvisiri kupa kutonga kwakakwana kwechirwere chako cheshuga.

Saxagliptin uye Dapagliflozin Zvinoshandiswa Kunei?

Mushonga uyu unonyanya kushandiswa kuvandudza kutonga kweshuga yeropa muvanhu vakuru vane chirwere cheshuga che mhando 2. Inowanzoitwa kana chirongwa chako chazvino chekudzora chirwere cheshuga chisiri kuchengeta mazinga eshuga yeropa rako mukati mehuwandu hwaunoda.

Chiremba wako angakurudzira musanganiswa uyu kana wakatotora rimwe remishonga iyi wega uye uchida kumwe kutonga shuga yeropa. Inogonawo kunyorerwa semushonga wekutanga wevanhu vachangobva kuwanikwa vane chirwere cheshuga type 2 vane mazinga akakwira zvikuru eshuga yeropa.

Kunze kwekutonga shuga yeropa, dapagliflozin mumusanganiswa uyu inogona kupa mamwe mabhenefiti. Vamwe vanhu vanowana kuderedzwa kwehuremu uye kuderedzwa kweropa, izvo zvinogona kubatsira zvikuru sezvo vanhu vazhinji vane chirwere cheshuga vachitongawo mamiriro aya. Zvisinei, mhedzisiro iyi inosiyana kubva kumunhu nemunhu.

Saxagliptin naDapagliflozin Vanoshanda Sei?

Mushonga uyu wemusanganiswa unoonekwa seune simba zvine mwero uye unoshanda kuburikidza nemaitiro maviri akasiyana kuderedza shuga yako yeropa. Chikamu chesaxagliptin chinowedzera mahomoni anonzi incretins, ayo anobatsira pancreas yako kuburitsa huwandu hwakakodzera hwe insulin paunodya uye kuratidza chiropa chako kuti chideredze kugadzirwa kweshuga.

Dapagliflozin inoshanda mumatsvo ako nekudzivisa protein inonzi SGLT2 iyo inowanzo tora shuga zvakare mumuviri wako. Kana protein iyi yakavharwa, shuga yakawandisa inosefa kuburikidza neweti yako panzvimbo yekugara muropa rako. Maitiro aya anoitika zvisinei ne insulin, zvichiita kuti ive nzira yakasiyana yekutonga chirwere cheshuga.

Pamwe chete, maitiro aya anogadzira nzira yakazara yekutonga shuga yeropa. Saxagliptin inobatsira muviri wako kupindura zviri nani kune zvekudya, nepo dapagliflozin ichipa kubviswa kweshuga nguva dzose zuva rese. Chiito ichi kaviri chinowanzoita kuti mazinga eshuga yeropa ave akagadzikana zvakanyanya nekuderera kwakanyanya uye kudonha.

Ndinofanira Kutora Sei Saxagliptin naDapagliflozin?

Tora mushonga uyu sezvakanyorwa nachiremba wako, kazhinji kamwe pazuva mangwanani. Unogona kuitora uine kana usina chikafu, asi vanhu vazhinji vanoona zviri nyore kuyeuka kana vachiitora nekudya kwemangwanani sechikamu chetsika yavo yemangwanani.

Momedza piritsi rese nemvura yakawanda. Usadziputsanya, kutsenga, kana kupatsanura piritsi, nekuti izvi zvinogona kukanganisa nzira iyo mushonga unoburitswa mumuviri mako. Kana uine dambudziko rekumedza mapiritsi, taura nachiremba wako nezve dzimwe nzira.

Sezvo dapagliflozin inowedzera kuita weti, kutora mushonga wako mangwanani kunobatsira kuderedza kufamba kuimba yekugezera usiku. Gara uine mvura yakawanda zuva rese, kunyanya munguva yezuva rinopisa kana paunenge uri kushanda zvakanyanya kupfuura zvakajairika. Muviri wako uchabvisa shuga kuburikidza neweti, saka kuchengetedza mvura yakawanda kwakakosha.

Ramba uchitora mushonga uyu kunyangwe ukanzwa zvakanaka. Chirwere cheshuga hachiwanzo kukonzera zviratidzo zvinooneka zuva nezuva, asi kushandiswa kwemishonga nguva dzose kunobatsira kudzivirira matambudziko enguva refu. Usambomira kutora mushonga uyu kamwechete usati wambotaura nemupi wehutano wako kutanga.

Ndingatora Saxagliptin naDapagliflozin kwenguva yakareba sei?

Vanhu vazhinji vane chirwere cheshuga chetype 2 vanofanira kutora mushonga uyu kwenguva refu kuti vachengetedze kutonga kwakanaka kweshuga yeropa. Chirwere cheshuga chirwere chisingaperi chinoda kurapwa nguva dzose, uye kumisa mushonga kazhinji kunotungamira kumazinga eshuga yeropa achidzokera kumazinga akakwira ekutanga.

Chiremba wako achatarisa mhinduro yako kumushonga kuburikidza nekuongororwa kweropa nguva dzose, kazhinji mwedzi mitatu kusvika mitanhatu yega yega. Miedzo iyi, kusanganisira chiyero chako cheA1C, inobatsira kuona kana mushonga uri kushanda zvakanaka kwauri. Zvichienderana nemigumisiro iyi, chiremba wako angachinja chiyero kana kugadzirisa chirongwa chako chekurapa.

Vamwe vanhu vanogona kuda kuchinja kurapwa kwavo sezvo chirwere cheshuga chingafambira mberi nekufamba kwenguva. Izvi hazvireve kuti mushonga wakamira kushanda, asi kuti zvaunoda nemuviri wako zvachinja. Chikwata chako chehutano chichashanda newe kugadzirisa chirongwa chako chekurapa sezvinodiwa kuti uchengetedze kutonga kwakanaka kweshuga yeropa.

Ndezvipi Zvakaipa ZveSaxagliptin naDapagliflozin?

Sezvinongoita mishonga yese, saxagliptin na dapagliflozin zvinogona kukonzera matambudziko, kunyangwe vanhu vazhinji vachizvigamuchira zvakanaka. Kunzwisisa zvekutarisa zvinogona kukubatsira kuti unzwe wakasununguka nezvekurapa kwako uye kuziva nguva yekubata chiremba wako.

Matambudziko anowanzoitika anowanzoita akapfava uye anowanzoita nani muviri wako paunojaira mushonga:

• Kuwedzera kuita weti, kunyanya mumavhiki mashoma ekutanga
• Kuwedzera nyota sezvo muviri wako uchijaira shanduko yemvura
• Zvirwere zvemugwagwa weti, zvakajairika muvakadzi
• Zvirwere zvembiriso munzvimbo yezvombo zvepabonde
• Mhino yakavharika kana inoyerera
• Huro inorwadza
• Musoro

Izvi zvinowanzoitika zvinowanzoita zvishoma sezvo muviri wako uchijaira mushonga. Kugara wakanyatsodiridzwa uye kuchengeta hutsanana hwakanaka kunogona kubatsira kuderedza mamwe ematambudziko aya.

Matambudziko akakomba haawanzoitiki asi anoda kutariswa kwechiremba nekukasira. Izvi zvinosanganisira zviratidzo zve ketoacidosis (kurutsa, kurutsa, kurwadziwa mudumbu, matambudziko ekufema), kupera mvura mumuviri zvakanyanya, kana kurwadziwa kusinganzwisisike kumusana kana padivi pako zvinogona kuratidza matambudziko eitsvo.

Vamwe vanhu vanogona kuona shuga yakaderera yeropa, kunyanya kana vachitora mamwe mishonga yeshuga. Tarisa zviratidzo zvakaita sekudedera, kutukutira, kurova kwemoyo nekukurumidza, kana kuvhiringidzika. Nguva dzose takura sosi yekukurumidza yeshuga senge mahwendefa eglucose kana muto.

Ndiani Asingafaniri Kutora Saxagliptin uye Dapagliflozin?

Mushonga uyu hauna kukodzera munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa usati wanyora. Vanhu vane chirwere cheshuga che rudzi rwekutanga havafaniri kutora musanganiswa uyu, sezvo wakagadzirirwa kunyanya manejimendi eshuga yerudzi rwechipiri.

Unofanira kudzivisa mushonga uyu kana uine chirwere cheitsvo chakakomba, sezvo dapagliflozin ichitsamira pabasa reitsvo kuti rishande nemazvo. Chiremba wako achaongorora basa reitsvo yako nemiedzo yeropa usati watanga mushonga uyu uye achaiongorora nguva dzose paunenge uchiiita.

Vanhu vane nhoroondo ye diabetic ketoacidosis vanofanira kushandisa mushonga uyu nekuchenjerera kukuru, sezvo SGLT2 inhibitors senge dapagliflozin dzimwe nguva dzinogona kuwedzera njodzi yechirwere ichi chakakomba. Chiremba wako achakurukura njodzi iyi newe kana ichikushanda iwe.

Zivisa chiremba wako kana wakazvitakura, uchironga kuzvitakura, kana kuyamwisa. Mushonga uyu hauna kudzidzwa zvakanyanya mumamiriro ezvinhu aya, uye chiremba wako anogona kukurudzira mamwe marapirwo akadzidzwa zviri nani panguva yekuzvitakura nekuyamwisa.

Zivisa mupi wako wehutano nezve chero allergies dzaunadzo, kunyanya ku saxagliptin, dapagliflozin, kana mishonga yakafanana. Taurawo kana uine matambudziko emoyo, chirwere chechiropa, kana nhoroondo ye pancreatitis, sezvo izvi zvingakanganisa kana mushonga uyu wakakunakira.

Mazita eSaxagliptin uye Dapagliflozin Brand

Mubatanidzwa we saxagliptin uye dapagliflozin unowanikwa pasi pezita remhando yeQtern. Zita remhando iyi rinomiririra piritsi remubatanidzwa re fixed-dose rine mishonga yese iri mune zviyero zvakatarwa.

Unogonawo kusangana nezvikamu zvega zvega pasi pemazita avo akasiyana emhando. Saxagliptin yega inotengeswa seOnglyza, nepo dapagliflozin pachayo inowanikwa seFarxiga. Zvisinei, chigadzirwa chemubatanidzwa Qtern chinopa nyore nyore yemishonga yese iri mupiritsi rimwe chete rezuva nezuva.

Vagadziri vakasiyana vanogona kugadzira shanduro dzakajairika dzemubatanidzwa uyu, une zvinhu zvakafanana zvinoshanda asi zvinogona kutaridzika zvakasiyana kubva kushanduro yezita remhando. Murapi wako wemishonga anogona kutsanangura chero misiyano mukuonekwa achisimbisa kuti simba remushonga uye zvinoshandiswa zvinoramba zvakafanana.

Saxagliptin uye Dapagliflozin Zvimwe Zvinhu

Mishonga yakati wandei inogona kubatsira kudzora chirwere cheshuga che rudzi rwechipiri kana saxagliptin uye dapagliflozin isiri iyo yakakodzera kwauri. Chiremba wako angatarisa mamwe mishonga yakasanganiswa inobatanidza makirasi akasiyana emishonga yeshuga zvichienderana nezvido zvako zvakakosha uye hutano hwako.

Mamwe masanganiswa eSGLT2 inhibitor anosanganisira empagliflozin ine linagliptin (Glyxambi) kana empagliflozin ine metformin (Synjardy). Izvi zvinoshanda zvakafanana ne saxagliptin uye dapagliflozin asi zvinogona kunge zvakakodzera mamiriro ako ega kana kugona kwako.

Kana mahwendefa akasanganiswa asina kukodzera, chiremba wako anganyora mishonga yega yega zvakasiyana. Iyi nzira inobvumira kugadzirisa kwakanyatsojeka kwemadosi uye inogona kubatsira kana iwe uine mhedzisiro kubva kune imwe chikamu asi uchishivirira imwe zvakanaka.

Mamwe makirasi emishonga yeshuga anosanganisira GLP-1 receptor agonists senge semaglutide (Ozempic) kana insulin preparations yevanhu vanoda kuwedzera manejimendi yeshuga yeropa. Chikwata chako chehutano chichashanda newe kuti uwane nzira yekurapa inonyatso shanda uye inoshivirirwa yemamiriro ako akasiyana.

Ko Saxagliptin uye Dapagliflozin Zviri Nani Kudarika Metformin?

Saxagliptin uye dapagliflozin hazvifanirwe kunge zviri nani pane metformin, asi panzvimbo pezvo inoshanda basa rakasiyana mukudzora chirwere cheshuga. Metformin inowanzoita mishonga yekutanga yakanyorwa ye rudzi rwechipiri rwechirwere cheshuga nekuti yakanyatso dzidzwa, inoshanda, uye inowanzo shivirirwa.

Iyi mishonga yakasanganiswa inowanzo shandiswa kana metformin yega isingape kutonga kwakakwana kweshuga yeropa, kana mukubatana ne metformin yevanhu vanoda mishonga yakawanda. Vanhu vazhinji vanotora ese ari maviri metformin uye iyi musanganiswa, sezvo vachishanda kuburikidza nemaitiro akasiyana.

Sarudzo pakati pemishonga inoenderana nemamiriro ako ega, kusanganisira mazinga ako e shuga yeropa, mamwe mamiriro ehutano, kushivirira kwemishonga, uye zvinangwa zvekurapa. Chiremba wako anofunga zvese izvi zvikonzero paanenge achisarudza nzira yakanakisa yemishonga kwauri.

Vamwe vanhu vanogona kubatsirwa zvakanyanya kubva mukubatanidzwa uku kana vachida mhedzisiro yekuwedzera iyo dapagliflozin inogona kupa, senge kuderedzwa kwehuremu kana kuderedzwa kweropa. Zvisinei, metformin inoramba iri mushonga wakanaka wekutanga wevanhu vazhinji vane chirwere cheshuga che mhando 2.

Mibvunzo Inowanzo Bvunzwa Nezve Saxagliptin uye Dapagliflozin

Saxagliptin uye Dapagliflozin Zvakachengeteka Here Kune Chirwere Chemoyo?

Kubatanidzwa uku kunogona kubatsira vanhu vane chirwere chemoyo, kunyanya nekuda kwechikamu che dapagliflozin. Zvidzidzo zvakaratidza kuti SGLT2 inhibitors senge dapagliflozin inogona kubatsira kuderedza njodzi yekuvharirwa muchipatara nekuda kwekutadza kwemoyo uye zviitiko zve cardiovascular muvanhu vane chirwere cheshuga.

Kubatsirwa kwe cardiovascular kunoita sekunopfuura kungodzora shuga yeropa. Dapagliflozin inogona kubatsira kuderedza kuchengetwa kwemvura uye kudzvanywa kweropa, izvo zvinogona kubatsira vanhu vanodzora zvese chirwere cheshuga uye mamiriro emoyo.

Zvisinei, chiremba wako wemoyo uye chiremba wechirwere cheshuga vanofanira kushanda pamwe chete kuti vave nechokwadi chekuti mushonga uyu unoenderana nemimwe mishonga yako yemoyo. Zvimwe zvigadziriso zvinogona kudiwa kudzivirira kudyidzana kana kuvandudza chirongwa chako chekurapa.

Ndoita Sei Kana Ndikatora Zvakawandisa Saxagliptin uye Dapagliflozin Netsaona?

Kana netsaona ukatora zvakawanda kupfuura chiyero chako chakatemwa, taura nemupi wako wehutano kana nzvimbo yekudzora chepfu nekukasira. Kutora zvakawanda kunogona kuwedzera njodzi yako yemhedzisiro, kunyanya shuga yeropa yakaderera uye kurasikirwa kwemvura yakawandisa.

Zvizvitarise iwe pachako kuti uone zviratidzo zvakaita sedzungaire, kuwanda kwemvura, nyota isinganzwisisike, kusvotwa, kana zviratidzo zve shuga yakaderera yeropa zvakaita sekudedera kana kuvhiringidzika. Kana ukaona zviratidzo zvakakomba, tsvaga rubatsiro rwekurapa nekukurumidza.

Usaedze kutsiva nekusvetuka mushonga wako unotevera. Pane kudaro, dzokera kuchirongwa chako chekushandisa mushonga sezvakarairwa nachiremba wako. Chengeta bhodhoro remushonga newe paunenge uchitsvaga rubatsiro rwekurapa kuitira kuti vanachiremba vaone chaizvo zvawatora uye zvakawanda sei.

Ndingaita Sei Kana Ndikakanganwa Dose yeSaxagliptin uye Dapagliflozin?

Kana ukakanganwa dose, itore paunenge uchiziva, kunze kwekunge yava nguva yechirongwa chako chinotevera. Muchiitiko ichocho, svetuka dose yakakanganwa uye uenderere mberi nechirongwa chako chese. Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yakakanganwa.

Kukanganwa dose dzimwe nguva hakuna njodzi, asi edza kuchengetedza kuenderana kuti uwane kutonga kwakanaka kweshuga yeropa. Funga nezvekuseta alarm yezuva nezuva kana kushandisa murongi wepiritsi kuti akubatsire kuyeuka maitiro ako emushonga.

Kana iwe uchikanganwa madosi kazhinji, taura nachiremba wako nezve nzira dzekuvandudza kutevedzera mushonga. Vanogona kukurudzira kutora dose yako panguva yakasiyana yezuva inokodzera maitiro ako, kana kukurukura mamwe masisitimu ekuyeuchidza anogona kubatsira.

Ndingamira Rini Kutora Saxagliptin uye Dapagliflozin?

Unofanira kungomira kutora mushonga uyu pasi pekutungamirirwa kwakananga kwechiremba wako. Kumira kamwe kamwe kunogona kukonzera kuti mazinga ako eshuga yeropa akwire nekukurumidza, zvichikonzera matambudziko akakomba.

Chiremba wako angangofunga kumisa kana kuchinja mushonga wako kana ukaona mativi akakosha, kana basa rako reitsvo richichinja, kana zvinangwa zvako zvekutarisira chirwere cheshuga zvichichinja zvakanyanya. Zvisarudzo izvi zvinogara zvichiitwa nekuchenjerera nekutarisa pedyo.

Vamwe vanhu vanogona kuchinja kumishonga yakasiyana sezvo chirwere chavo cheshuga chichienderera mberi kana zvinodiwa zvavo zvehutano zvichichinja. Ichi chikamu chakajairika chekutungamira chirwere cheshuga, uye chikwata chako chekuchengetedza hutano chichakutungamira kuburikidza nekuchinja kwese kuti uve nechokwadi chekurapa kunoenderera mberi, kunobudirira.

Ndinganwa Doro Ndichitora Saxagliptin uye Dapagliflozin here?

Unogona kunwa doro zvine mwero uchitora mushonga uyu, asi zvinoda kufunga nekugadzirira zvakanyanya. Doro rinogona kukanganisa mazinga ako eshuga yeropa uye rinogona kuwedzera njodzi yekushaya mvura kana yakasanganiswa ne dapagliflozin.

Ganhurira kunwa doro kusvika kune chinwiwa chimwe chete pazuva chevakadzi uye zvinwiwa zviviri pazuva zvevarume, uye nguva dzose unwa doro nechikafu kubatsira kudzivirira shuga yeropa yakaderera. Tarisa shuga yako yeropa kakawanda paunenge uchinwa, sezvo doro rinogona kuviga zviratidzo zve shuga yeropa yakaderera.

Chenjerera zvakanyanya kugara uine mvura paunenge uchidya doro, sezvo doro uye dapagliflozin zvose zvinogona kuita kuti mvura ibude. Taura nemupi wako wehutano nezve tsika dzako dzekunwa doro kuti vakwanise kupa gwara rakagadzirirwa zvinoenderana nehutano hwako hwese uye chirongwa chekutungamira chirwere cheshuga.