Created at:1/13/2025
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Saxagliptin uye metformin mushonga unosanganiswa unobatsira kudzora chirwere cheshuga che mhando 2 nekushanda nenzira mbiri dzakasiyana dzekudzora mazinga eshuga yeropa. Mushonga uyu unobatanidza mishonga miviri yakaratidza kubudirira yekurapa chirwere cheshuga mune piritsi rimwe riri nyore, zvichiita kuti zvive nyore kuti iwe unamate kuronga kwako kurapa.
Kana iwe wakanyorerwa mushonga uyu, ungangove uchishamisika kuti unoshanda sei uye zvekutarisira. Ngatitarisei zvese zvaunoda kuziva nezve mushonga uyu wechirwere cheshuga nenzira inoita seinodzoreka uye yakajeka.
Saxagliptin uye metformin mushonga unonyorerwa une zvinoshanda zviviri zvinoshanda pamwechete kubatsira kudzora shuga yeropa muvanhu vane chirwere cheshuga che mhando 2. Funga nezvazvo semaitiro echikwata uko mushonga wega wega unokurira shuga yeropa kubva kune imwe kona.
Saxagliptin ndeyeboka remishonga inonzi DPP-4 inhibitors, iyo inobatsira muviri wako kugadzira insulin yakawanda kana shuga yako yeropa yakwira. Metformin ndeyeboka rinonzi biguanides, uye inobatsira kuderedza huwandu hweshuga inogadzirwa nechiropa chako uku ichibatsirawo muviri wako kushandisa insulin zvakanyanya.
Mushonga uyu unosanganiswa unowanikwa setableti yaunotora nemuromo, kazhinji kaviri pazuva nezvokudya. Chiremba wako anonyora izvi kana mishonga imwe chete isingapi kutonga kwakakwana kweshuga yeropa yega.
Mushonga uyu wakagadzirirwa kurapa chirwere cheshuga che mhando 2 muvanhu vakuru kana kudya uye kurovedza muviri chete zvisina kukwana kudzora mazinga eshuga yeropa. Zvinobatsira zvikuru kune vanhu vanoda mhando imwe chete yemushonga wechirwere cheshuga kuti vasvike pazvinangwa zvavo zveshuga yeropa.
Chiremba wako angakupa mushonga uyu kana wanga uchitora metformin yoga asi uchine shuga yakawanda muropa rako. Inoshandiswawo kana uchida mishonga yese miviri asi uchida nyore yekutora piritsi rimwe panzvimbo pemapiritsi maviri akasiyana.
Mishonga iyi inoshanda zvakanyanya sechikamu chechirongwa chakazara chekudzora chirwere cheshuga chinobatanidza kudya zvakanaka, kurovedza muviri nguva dzose, uye kudzora uremu kana zvakakodzera. Haina chinangwa chekutsiva nzira idzi dzakakosha dzekurarama nadzo asi kushanda pamwe chete nadzo.
Mishonga iyi inoshanda nenzira mbiri dzakasiyana kubatsira kuchengeta shuga yako yeropa iri muchiyero chakanaka. Chikamu chesaxagliptin chinobatsira pancreas yako kuburitsa insulin yakawanda kana shuga yako yeropa yakwira mushure mekudya, ukuwo ichideredza huwandu hweglucose rinogadzirwa nechiropa chako.
Chikamu chemetformin chinonyanya kushanda nekuderedza huwandu hwe shuga inogadzirwa nechiropa chako uye inoburitswa muropa rako. Inobatsirawo maseru ako emhasuru nemafuta kuti ave sensitive kune insulin, zvinoreva kuti anogona kushandisa glucose zvakanyanya.
Pamwe chete, mishonga iyi miviri inopa izvo vanachiremba vanoti “moderate” level yekudzora shuga yeropa. Kunyangwe isiri mishonga yakasimba yechirwere cheshuga iripo, musanganiswa uyu unowanzo shanda zvakanyanya kune vanhu vazhinji uye unowanzoita mashoma mativi pane mamwe marapirwo akanyanya.
Tora mushonga uyu sezvaunorairwa nachiremba wako, kazhinji kaviri pazuva nekudya kwako kwemangwanani nekwemanheru. Kuitora nekudya kunobatsira kuderedza dumbu uye kunobvumira mushonga kuti ushande zvakanyanya nekupindura kwemuviri wako kune insulin pakudya.
Medza mahwendefa ese nemvura yakawanda - usapwanya, kutsenga, kana kuapwanya. Kana uine dambudziko rekumedza mapiritsi, taura nachiremba wako nezve dzimwe nzira panzvimbo yekuedza kugadzirisa mahwendefa iwe pachako.
Edza mishonga yako panguva imwechete zuva rega rega kuti uchengetedze huwandu hwemishonga mumuviri mako. Vanhu vazhinji vanoona zvichibatsira kubatanidza kutora mishonga yavo nekudya kwenguva dzose, sekudya kwemangwanani nekudya kwemanheru, kuti vagadzire tsika inowirirana.
Usati watanga mushonga uyu, idya chikafu chakareruka kana snack kuti ubatsire kudzivirira kusagadzikana mudumbu. Zvokudya zviri nyore mudumbu mako, zvakaita setoast, crackers, kana yogurt, zvinoshanda zvakanaka kana uchinetseka nekusvotwa.
Rudzi rwechipiri rwechirwere cheshuga chirwere chenguva refu, saka vanhu vazhinji vanofanira kutora mushonga uyu kwemakore mazhinji kana kunyange nekusingaperi kuti vachengetedze kutonga kwakanaka kweshuga yeropa. Chiremba wako achatarisa nguva dzose mazinga eshuga yeropa rako uye hutano hwako hwese kuti aone kana mushonga uyu ucharamba uri sarudzo yakakunakira.
Mumwedzi yako yekutanga mishonga iyi, ungangove uine maonero ekutarisa uye bvunzo dzeropa kakawanda kuti uve nechokwadi chekuti iri kushanda zvakanaka uye haina kukonzera matambudziko. Mushure meizvozvo, vanhu vazhinji vanoongorora mishonga yavo yechirwere cheshuga mwedzi mitatu kusvika mitanhatu yega yega.
Chiremba wako anogona kugadzirisa muyero wako kana kukuchinjira kumimwe mishonga nekufamba kwenguva sezvo zvinodiwa nemuviri wako zvichichinja. Izvi zvakajairika uye hazvireve kuti mushonga haushandi - zvinongoreva kuti chirongwa chako chekurapa chiri kugadziridzwa kuti chifanane nehutano hwako hwazvino.
Semishonga yese, saxagliptin uye metformin inogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachizvitsungirira zvakanaka. Mhedzisiro yakajairika inowanzoita nyoro uye inowanzoita nani sezvo muviri wako uchigadzirisa kumishonga mumavhiki mashoma ekutanga.
Heano mhedzisiro yaungangove uine, uchifunga kuti nyaya dzine chekuita nedumbu ndidzo dzakajairika:
Izvi zvinowanzoitika zvinogona kugadziriswa uye zvinongogara kwenguva pfupi. Kutora mushonga uyu pamwe chete nechikafu uye kutanga nemadosi madiki kunogona kubatsira kuderedza matambudziko mudumbu.
Zvino, ngatitaure nezve mamwe matambudziko asingawanzoitiki asi akakomba anoda kutariswa nachiremba nekukasira:
Kunyangwe izvi zvinokonzera matambudziko akakomba zvisingawanzoitiki, zvakakosha kuzviziva nekukurumidza. Kana ukaona chero zviratidzo izvi, taura nachiremba wako nekukasira kana kutsvaga rubatsiro rwekurapa rwekukurumidza.
Pane zvakare mamiriro asingawanzoitiki asi akakomba anonzi lactic acidosis anogona kuitika nemetformin. Izvi zvinoitika kana lactic acid ichiunganidzwa muropa rako nekukurumidza kupfuura muviri wako unogona kuibvisa. Zviratidzo zvekuyambira zvinosanganisira kurwadziwa kwemhasuru kusingawanzoitiki, kutadza kufema, kurwadziwa mudumbu, dzungu, uye kunzwa usina simba kana kuneta.
Mushonga uyu hauna kukodzera munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa usati wamupa. Vanhu vane mamwe mamiriro ehutano kana mamiriro vanofanirwa kudzivisa mushonga uyu wemubatanidzwa zvachose.
Haufanire kutora mushonga uyu kana uine chirwere cheshuga chetype 1 kana diabetic ketoacidosis, sezvo yakagadzirirwa zvakananga manejimendi echirwere cheshuga chetype 2. Izvo zvakare hazvikurudzirwe kana uine allergic ku saxagliptin, metformin, kana chero zvimwe zvinosanganiswa mumushonga.
Heano mamiriro ehutano chaiwo anoita kuti mushonga uyu usakodzere kana kuda kungwarira kwakakosha:
Chiremba wako achavawo akangwarira nezvekupa mushonga uyu kana wakarongerwa kuvhiyiwa kana mamwe maitiro ekurapa anoda ruvara rwekupesana, sezvo ungada kumisa mushonga kwenguva pfupi panguva idzi.
Kana uri nepamuviri, kuronga kuva nepamuviri, kana kuyamwisa, taura izvi nachiremba wako. Nepo metformin dzimwe nguva ichishandiswa panguva yekuzvitakura, kuchengeteka kwe saxagliptin panguva yekuzvitakura hakuna kumiswa zvizere, saka mamwe marapirwo angave akakodzera.
Zita rinowanzozivikanwa remushonga uyu mubatanidzwa ndiKombiglyze XR, iyo ndiyo vhezheni yakawedzerwa-kusunungurwa yaunowanzo tora kamwe pazuva. Kune zvakare vhezheni yekusunungurwa nguva dzose inotorwa kaviri pazuva.
Unogonawo kuona mavhezheni e generic emubatanidzwa uyu, ane zvinhu zvakafanana zvinoshanda asi zvinogadzirwa nemakambani akasiyana emishonga. Generic versions inoshanda sezvakaita mishonga yemhando uye kazhinji inodhura zvishoma.
Pharmacy yako inogona kutsiva vhezheni ye generic kunze kwekunge chiremba wako achinyatsokumbira zita remhando. Izvi zvakajairika uye zvakachengeteka - zvinoshanda zvinoshanda uye kushanda zvinoramba zvakafanana.
Kana mubatanidzwa uyu usingashande zvakanaka kwauri kana kukonzera mhedzisiro inonetsa, akati wandei ekurapa anowanikwa. Chiremba wako anogona kukubatsira kuwana mushonga wakakodzera kana mubatanidzwa unoshanda zvakanyanya kune yako chaiyo mamiriro.
Dzimwe nzira dzekubatanidza DPP-4 inhibitor uye metformin dzinosanganisira sitagliptin uye metformin (Janumet) kana linagliptin uye metformin (Jentadueto). Izvi zvinoshanda zvakafanana asi zvinogona kushandiswa zviri nani nevamwe vanhu.
Kana usingakwanise kutora metformin nekuda kwematambudziko eitsvo kana mhedzisiro, chiremba wako anogona kuraira saxagliptin ega kana kuibatanidza nemimwe mishonga yechirwere cheshuga senge insulin kana SGLT2 inhibitors.
Kune vanhu vanoda mishonga inojekiswazve, GLP-1 receptor agonists senge semaglutide kana liraglutide inogona kuve dzimwe nzira dzakanaka dzinowanzoita kuti shuga yeropa idzoreke zviri nani uye inogona kubatsira mukurasikirwa nehuremu.
Ose ari maviri saxagliptin uye metformin (Kombiglyze) uye sitagliptin uye metformin (Janumet) mishonga yakafanana inoshanda nenzira dzakafanana. Vese vari DPP-4 inhibitors vakabatanidzwa ne metformin, uye tsvagiridzo inoratidza kuti vane kushanda kwakafanana mukudzikisa mazinga eshuga yeropa.
Sarudzo pakati pemishonga iyi inowanzoenderana nezvinhu zvakaita semhedzisiro, nyore kwekuisa mushonga, mutengo, uye inishuwarenzi. Vamwe vanhu vanoshivirira imwe zviri nani pane imwe, kunyangwe vanhu vazhinji vachifara nechero sarudzo.
Chiremba wako achafunga nezve mamiriro ako ehutano, mimwe mishonga yaunotora, uye zvaunofarira iwe pachako paunenge uchisarudza pakati pezvisarudzo izvi. Zvese zvinoonekwa sezvakachengeteka uye zvinoshanda kurapa kwekutanga kwechirwere cheshuga che2.
Kazhinji, iyi musanganiswa inoonekwa seyakachengeteka kune vanhu vane chirwere chemoyo, uye metformin inogona kunyange kupa mamwe mabhenefiti ekudzivirira moyo. Zvisinei, chiremba wako achada kukutarisa zvakanyanya kana uine moyo kukundikana kana mamwe mamiriro emoyo akakomba.
Mishonga iyi haiwanzo kukonzera matambudziko emoyo muvanhu vane hutano, asi zvakakosha kuti uudze chiremba wako nezve chero matambudziko emoyo aunavo. Vanogona kuchinja mushonga wako kana kusarudza mishonga yakasiyana kana uine kutadza kwemoyo kwakanyanya.
Kana netsaona ukatora zvakawandisa zve mushonga uyu, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasika, kunyangwe ukanzwa zvakanaka. Kutora metformin yakawandisa kunogona kukonzera mamiriro akakomba anonzi lactic acidosis, iyo inoda kutariswa kwekurapa nekukasika.
Tarisa zviratidzo zvakaita se kurwadziwa kwemhasuru kusinganzwisisike, matambudziko ekufema, kurwadziwa mudumbu, dzungu, kana kunzwa usina simba zvakanyanya. Usamirira kuti zviratidzo zviitike usati watsvaga rubatsiro - fonera chiremba wako nekukasika kana wakatora zvakawanda kupfuura zvakarairwa.
Kana ukakanganwa dose, itore paunorangarira, asi chete kana isiri pedyo nedose yako inotevera yakarongwa. Kana yava nguva yechikamu chako chinotevera, skip iyo yakarasika uye uenderere mberi nechirongwa chako chetsika.
Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yakarasika, sezvo izvi zvinogona kuwedzera njodzi yako yemigumisiro. Kana iwe uchikanganwa madosi kazhinji, funga nezvekuseta zviyeuchidzo zvefoni kana kushandisa chirongwa chemapiritsi kuti zvikubatsire kuti urambe uri munzira.
Unofanirwa kungomira kutora mushonga uyu pasi pekutungamirirwa nachiremba wako. Type 2 diabetes imamiriro ehupenyu hwese, saka vanhu vazhinji vanoda kuramba vachitora mishonga ye diabetes zvachose kuti vachengetedze kutonga kwakanaka kweshuga yeropa.
Chiremba wako anogona kuchinja mishonga yako nekufamba kwenguva zvichienderana nemazinga eshuga yeropa, migumisiro, kana shanduko muhutano hwako. Kana iwe uchinetseka nezve kutora mushonga kwenguva refu, kurukura manzwiro ako nachiremba wako - vanogona kukubatsira kunzwisisa mabhenefiti uye kugadzirisa chero zvinokunetsa.
Unogona kunwa doro zvishoma, zvine mwero uchitora mushonga uyu, asi zvakakosha kungwarira. Doro rinogona kuwedzera njodzi yako yekuva ne lactic acidosis, kunyanya kana ukanwa zvakanyanya kana kunwa zvakanyanya.
Paunonwa, ita doro nechikafu uye zvigumire kunwa kamwe chete pazuva kana uri mukadzi kana zvinwiwa zviviri pazuva kana uri murume. Nguva dzose kurukura kunwa kwako doro nachiremba wako, sezvo vachigona kupa gwara rakagadzirirwa zvinoenderana nehutano hwako hwese.