Chii chinonzi Saxagliptin: Zvazvinoshandiswa, Mishonga, Mativi eMuviri, nezvimwe zvakawanda

Saxagliptin mushonga unopiwa nachiremba unobatsira vanhu vane chirwere cheshuga che rudzi rwechipiri kudzora mazinga eshuga yeropa ravo. Iwo wekirasi yemishonga inonzi DPP-4 inhibitors, iyo inoshanda nekubatsira muviri wako kugadzira insulin yakawanda kana shuga yeropa rako yakwira uye kuderedza huwandu hweshuga inogadzirwa nechiropa chako.

Mushonga uyu unowanzo piwa kana kudya uye kurovedza muviri chete zvisina kukwana kudzora shuga yeropa, kana kana mimwe mishonga yeshuga ichida rubatsiro rwekuwedzera. Vanhu vazhinji vanowana saxagliptin sekuwedzera kunononoka asi kunobudirira kuronga kwavo chirwere cheshuga.

Chii chinonzi Saxagliptin?

Saxagliptin mushonga wekushandisa muromo wechirwere cheshuga waunotora nemuromo, kazhinji kamwe pazuva. Yakagadzirirwa kushanda nehurongwa hwekuita insulin yemuviri wako pachinzvimbo chekumanikidza shanduko huru mushuga yeropa rako.

Funga nezve saxagliptin semubatsiri anobatsira kune pancreas yako. Kana shuga yeropa rako yakwira mushure mekudya, inoratidza pancreas yako kuti ibudise insulin yakawanda. Panguva imwecheteyo, inoudza chiropa chako kuti chinonoke kugadzirwa kweshuga, ichigadzira nzira yakanyanya kuenzana yekudzora shuga yeropa.

Mushonga uyu unoonekwa semushonga wechirwere cheshuga wepakati nepakati. Haina hukasha sejekiseni re insulin, asi yakatarwa zvakanyanya pane shanduko dzemaitiro chete. Vanhu vazhinji vanoishivirira zvakanaka nekuti inoshanda zvinyoro nyoro nemasisitimu emuviri wako aripo.

Saxagliptin inoshandiswa nei?

Saxagliptin inonyanya kushandiswa kurapa chirwere cheshuga che rudzi rwechipiri muvanhu vakuru. Chiremba wako angangokupa mushonga uyu kana urongwa hwako hwekudzora chirwere cheshuga huchida rubatsiro rwekuwedzera kuti usvike pazvinangwa zvako zveshuga yeropa.

Heano mamiriro makuru apo saxagliptin inobatsira:

• Kana kudya uye kurovedza muviri zvoga zvisiri kudzora shuga yeropa rako zvakakwana
• Sezvinowedzerwa kune metformin kana metformin yoga isingakwani
• Mukubatanidzwa nemimwe mishonga yechirwere cheshuga senge insulin kana sulfonylureas
• Kana uchida mushonga usingazokonzeri kuwedzera uremu zvakanyanya
• Kana uri kutsvaga sarudzo yekutora kamwe chete pazuva inokodzera nyore nyore muroutine yako

Mupi wako wehutano achasarudza kana saxagliptin yakakodzera mamiriro ako chaiwo. Vachafunga nezve mazinga ako eshuga yeropa aripo, mimwe mishonga yaunotora, uye mufananidzo wako wehutano hwese.

Saxagliptin Inoshanda Sei?

Saxagliptin inoshanda nekudzivisa enzyme inonzi DPP-4 mudumbu rako. Iyi enzyme inowanzoita kuti mahomoni anobatsira anodzora shuga yeropa aparadzwe, saka nekuivharira, saxagliptin inobvumira mahomoni aya echisikigo kuti ashande kwenguva refu uye zvinobudirira.

Paunodya, matumbu ako anoburitsa mahomoni anonzi incretins ayo anoratidza pancreas yako kuti ibudise insulin. Saxagliptin inobatsira mahomoni aya kuti arambe achishanda kwenguva refu, izvo zvinoreva kuti muviri wako unogona kupindura zvakakodzera kumazinga eshuga yeropa ari kukwira.

Uyu mushonga unoonekwa semushonga wechirwere cheshuga wepakati nepakati. Iwo munyoro kupfuura insulin kana sulfonylureas nekuti inoshanda chete kana shuga yako yeropa yakakwira. Kana shuga yako yeropa yakajairika, saxagliptin haina zvayakaita, izvo zvinoderedza njodzi yezviitiko zvine njodzi zveshuga yeropa yakaderera.

Runako rwemaitiro aya nderekuti anoshanda nerwiyo rwemuviri wako. Hauvamanikidzi pancreas yako kuti ishande nguva dzese, ingoipa maturusi ari nani ekuita basa rayo kana zvichidikanwa.

Ndingatora Sei Saxagliptin?

Saxagliptin inowanzo torwa kamwe chete pazuva, uine kana pasina chikafu. Vanhu vazhinji vanozviwana zviri nyore kuti vatore panguva imwe chete zuva rega rega kuti vachengetedze mazinga akagadzikana muhurongwa hwavo.

Unogona kutora saxagliptin nemvura, mukaka, kana muto. Kusiyana nemimwe mishonga, haidi nguva yakakosha nemadyiro. Zvisinei, kuitora nechikafu kungabatsira kana ukawana chero dumbu rinogumbura, kunyange izvi zvisingawanzoitiki.

Hezvino zvakanakira vanhu vazhinji:

• Sarudza nguva imwechete zuva rega rega, senge nekudya kwemangwanani kana kudya kwemanheru
• Misa piritsi rose negirazi remvura izere
• Usapwanya kana kutsenga piritsi
• Kana uchiitora nechikafu, chero chikafu chipi zvacho chakajairika chakanaka
• Ramba uchiitora kunyangwe ukanzwa zvakanaka, sezvo manejimendi echirwere cheshuga achienderera mberi

Chiremba wako achakutanga padosi yakakodzera zvichienderana nebasa rako reitsvo nezvimwe zvinhu zvehutano. Vanhu vazhinji vanotanga ne2.5 mg kana 5 mg kamwe pazuva, uye izvi zvinowanzoita dosi yenguva refu.

Ndingatora Saxagliptin Kwenguva Yakareba Sei?

Saxagliptin inowanzoita mushonga wenguva refu waunozoramba uchitora chero bedzi ichibatsira kudzora chirwere chako cheshuga zvinobudirira. Type 2 chirwere cheshuga chirwere chisingaperi chinoda manejimendi anoenderera mberi, saka vanhu vazhinji vanoramba vachitora mishonga yavo yechirwere cheshuga kwenguva isingagumi.

Chiremba wako achatarisa mazinga eshuga yeropa rako uye hutano hwako hwese nguva dzose kuti ave nechokwadi chekuti saxagliptin inoramba iri sarudzo yakakunakira. Ivo vanowanzoongorora mazinga ako eA1C mwedzi mitatu kusvika kumatanhatu ega ega kuti vaone kuti chirongwa chako chekudzora chirwere cheshuga chiri kushanda sei.

Vamwe vanhu vangada kugadzirisa mishonga yavo yechirwere cheshuga nekufamba kwenguva. Izvi hazvireve kuti saxagliptin yakamira kushanda, asi kuti chirwere cheshuga chinogona kuchinja nekushanduka. Chikwata chako chehutano chichashanda newe kuti uite chero kugadzirisa kunodiwa kuti uchengetedze shuga yako yeropa mumwero wehutano.

Usambomira kutora saxagliptin kamwechete usina kutaura nachiremba wako kutanga. Kunyangwe iwe uchinzwa zvakanaka, shuga yako yeropa inogona kukwira kumazinga ane njodzi pasina manejimendi akakodzera emishonga.

Ndezvipi Zvipingamupinyi zveSaxagliptin?

Vanhu vazhinji vanogona kushandisa saxagliptin zvakanaka, asi semishonga yese, inogona kukonzera mhedzisiro. Mashoko akanaka ndewekuti mhedzisiro yakakomba haisi yakajairika, uye vanhu vazhinji havana mhedzisiro zvachose.

Heano mhedzisiro yakajairika iyo vamwe vanhu vanowana:

• Kutemwa nemusoro
• Zvirwere zvepamusoro zvekufema (sekutonhora)
• Zvirwere zvemudzira
• Kurwadziwa mudumbu kana kusagadzikana
• Kusvotwa

Mhedzisiro iyi yakajairika inowanzoita nyoro uye inowanzoita nani sezvo muviri wako uchigadzirisa kumishonga. Kana ikaramba kana kuva inoshungurudza, zivisa chiremba wako.

Kune dzimwe mhedzisiro isingawanzoitiki asi yakakomba iyo inoda kutariswa kwekurapa nekukurumidza:

• Kurwadziwa kwakanyanya mumajoini kusingavandudzi
• Zviratidzo zvepancreatitis (kurwadziwa kwakanyanya mudumbu kunogona kupararira kumusana wako)
• Maitiro ekuita allergic (rash, kukwenya, kuzvimba, kuoma kufema)
• Zviratidzo zvekukundikana kwemoyo (kuzvimba mumakumbo, kufema zvishoma, kuneta kusinganzwisisike)
• Maitiro akakomba eganda kana kuita mablister

Kunyangwe mhedzisiro iyi yakakomba isingawanzoitiki, zvakakosha kuziva nezvayo uye taura nachiremba wako nekukurumidza kana uine chero zviratidzo izvi.

Ndiani Asingafaniri Kutora Saxagliptin?

Saxagliptin haikodzeri munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akuisa. Kune mamiriro chaiwo apo mushonga uyu unofanirwa kudzivirirwa kana kushandiswa nekuchenjerera kwakanyanya.

Haufanire kutora saxagliptin kana uine:

• Type 1 diabetes (inongobvumidzwa chete ye type 2)
• Nhoroondo yemaitiro akakomba ekuita allergic ku saxagliptin kana mishonga yakafanana
• Diabetic ketoacidosis (dambudziko rakakomba re shuga)
• Zvirwere zvakakomba zveitsvo (chiremba wako angangoda kugadzirisa muyero kana kusarudza mushonga wakasiyana)

Chiremba wako achashandisa saxagliptin nekuchenjerera kwakanyanya kana uine:

• Nhoroondo yekukundikana kwemoyo
• Matambudziko eitsvo (kunyangwe matambudziko madiki anogona kuda kugadziriswa kwemishonga)
• Nhoroondo ye pancreatitis
• Matombo emumudzi we nduru kana matambudziko emumudzi we nduru
• Nhoroondo yematambudziko akakomba emajoini

Nguva dzose udza chiremba wako nezve mamiriro ako ese ehutano nemishonga usati watanga saxagliptin. Izvi zvinovabatsira kuti vaone kana iri sarudzo yakachengeteka uye inoshanda zvakanyanya pakurapa chirwere chako cheshuga.

Zita reSaxagliptin Brand

Saxagliptin inowanikwa pasi pezita rekuti Onglyza. Unogona zvakare kuiwana ichibatanidzwa nemimwe mishonga yechirwere cheshuga pasi pemazita akasiyana emhando.

Kubatanidzwa kwe saxagliptin ne metformin kunotengeswa seKombiglyze XR. Iri piritsi rinobatanidzwa rinogona kuve nyore kune vanhu vanoda mishonga yese, sezvo ichideredza huwandu hwemapiritsi aunofanirwa kutora zuva rega rega.

Kunyangwe iwe ukagamuchira zita remhando kana vhezheni yakajairika, chinhu chinoshanda uye kushanda zvakafanana. Chirongwa chako cheinishuwarenzi uye pharmacy zvinogona kukanganisa kuti ndeipi vhezheni yaunogamuchira, asi ese ari maviri anoshanda zvakaenzana pakudzora shuga yeropa.

Zvimwe Zvinhu Zvokutsiva Saxagliptin

Kana saxagliptin isiri iyo yakakunakira, kune mamwe mishonga yechirwere cheshuga inoshanda nenzira dzakafanana kana dzakasiyana. Chiremba wako anogona kukubatsira kuti uongorore sarudzo idzi zvichibva pazvido zvako zvakananga uye mamiriro ehutano.

Zvimwe zvinodzora DPP-4 zvinoshanda zvakafanana ne saxagliptin zvinosanganisira:

• Sitagliptin (Januvia)
• Linagliptin (Tradjenta)
• Alogliptin (Nesina)

Makirasi akasiyana emishonga yechirwere cheshuga iyo chiremba wako angangofunga kusanganisira:

• Metformin (kazhinji kurapwa kwekutanga)
• GLP-1 receptor agonists (se semaglutide kana liraglutide)
• SGLT-2 inhibitors (se empagliflozin kana canagliflozin)
• Sulfonylureas (se glipizide kana glyburide)
• Insulin (yekurapa chirwere cheshuga chakanyanya)

Nzira yakanakisa inobva pamamiriro ako ehutano, mishonga yaunotora, uye zvinangwa zvako zvekudzora chirwere cheshuga. Chiremba wako achashanda newe kuti awane sarudzo inoshanda zvakanyanya uye inotsungirirwa zvakanaka.

Ko Saxagliptin iri nani pane Sitagliptin?

Ose ari maviri saxagliptin uye sitagliptin ndiDPP-4 inhibitors anoshanda zvakanyanya kufanana nekudzora chirwere cheshuga chetype 2. Hapana mushonga wakanyatso "kuti uri nani" pane mumwe, sezvo ese ari sarudzo dzinoshanda dzine zvakafanana zvinobatsira uye mhedzisiro yezvinhu.

Musiyano mukuru pakati pemishonga iyi unonyengera. Sitagliptin yanga iripo kwenguva refu uye ine ruzivo rwakawanda rwekutsvaga. Saxagliptin inogona kunge iine mhedzisiro yakasiyana zvishoma, nedzimwe zvidzidzo zvichiratidza mhedzisiro yakasiyana pamoyo, kunyangwe ese ari maviri achionekwa seakachengeteka.

Sarudzo yachiremba wako pakati pemishonga iyi inowanzoenderana ne:

• Mabasa ako eitsvo (kugadzirisa dosing kunogona kusiyana)
• Mishonga mimwe yaunotora
• Inishuwarenzi yako uye mari yemishonga
• Mamiriro ako ehutano chaiwo uye njodzi
• Kuti wakanaka sei pakupindura kune mamwe mishonga yechirwere cheshuga

Mishonga yese iri miviri inotorwa kamwe chete pazuva uye inoshanda zvakanaka pamwe chete nemamwe marapirwo echirwere cheshuga. Sarudzo "yakanaka" ndiyo inonyatso shanda zvakanyanya kumamiriro ako ega uye inokubatsira kuti uwane zvinangwa zvako zve shuga yeropa nemhedzisiro shoma.

Mibvunzo Inowanzo Bvunzwa Nezve Saxagliptin

Saxagliptin Yakachengeteka Kune Vanhu vane Chirwere Chemoyo Here?

Saxagliptin inoda kufunga zvakanyanya kana uine chirwere chemoyo, kunyanya kukundikana kwemoyo. Zvimwe zvidzidzo zvakaratidza kuwedzera kushoma kwekuvharirwa kwevanhu vane kukundikana kwemoyo pakutora saxagliptin, kunyanya avo vane matambudziko emoyo aripo.

Asi, izvi hazvirevi kuti saxagliptin haina kuchengeteka otomatiki kune vanhu vane chirwere chemoyo. Chiremba wako achayerera mabhenefiti ekudzora shuga yeropa achienzanisa nenjodzi dzinogona kuitika kumoyo. Vachakutarisa zvakanyanya uye vanogona kukurudzira kuongororwa kwemoyo nguva dzose kana uine chero matambudziko emoyo.

Kana uine chirwere chemoyo, ita shuwa kuti unokurukura izvi zvakadzama nemupi wako wehutano. Vanogona kusarudza mushonga wechirwere cheshuga wakasiyana kana kutora matanho ekuwedzera ekutarisa hutano hwemoyo wako paunenge uchitora saxagliptin.

Ndingaita Sei Kana Ndikatora Saxagliptin Yakawandisa Netsaona?

Kana netsaona ukatora saxagliptin yakawanda kupfuura yakarairwa, usavhunduka. Kutora dose kaviri dzimwe nguva hazvingakonzere kukuvadza zvakanyanya, asi unofanirwa kuchine kubata mupi wako wehutano kana nzvimbo yekudzora chepfu kuti uwane gwara.

Zvitarise iwe pachako kuti uone zviratidzo zvakaita sekuvhunduka, kurutsa, kurwadziwa mudumbu, kana kuneta kusinganzwisisike. Kunyange saxagliptin kazhinji haikonzeri shuga yeropa yakaderera ine njodzi yega, kutora yakawanda zvakanyanya kunogona kukonzera zviratidzo izvi, kunyanya kana uchitora mamwe mishonga yechirwere cheshuga.

Fonera chiremba wako, muzvinamutsa, kana nzvimbo yekudzora chepfu (1-800-222-1222 muUS) kana uine hanya nekutora yakawanda. Vanogona kupa gwara rakatarwa zvichienderana nekuti wakatora yakawanda sei uye mamiriro ako ehutano ega. Usaedze "kugadzirisa" dose yekuwedzera nekusvetuka dose yako inotevera yakarongwa.

Ndingaita Sei Kana Ndikakanganwa Dose yeSaxagliptin?

Kana ukakanganwa dose ye saxagliptin, itore paunorangarira, kunze kwekunge yava nguva yechikamu chako chinotevera chakarongeka. Muchiitiko ichocho, svetuka dose yakakanganwa uye uenderere mberi nechirongwa chako chetsika.

Usambofa wakatora madosi maviri panguva imwe chete kuti ugadzirise dose yakakanganwa. Izvi zvinogona kuwedzera njodzi yako yemigumisiro isingadiwi pasina kupa imwe mhinduro yekudzora shuga yako yeropa.

Kukanganwa mushonga dzimwe nguva hakuna njodzi, asi edza kuchengetedza nguva dzose kuti utarise zvakanaka chirwere cheshuga. Funga nezvekuisa chiyeuchidzo pafoni yako zuva rega rega kana kushandisa chirongwa chemishonga kuti zvikubatsire kuyeuka nguva yako yemishonga.

Ndingamira Rini Kutora Saxagliptin?

Unofanira kungomira kutora saxagliptin pasi pekutungamirirwa nachiremba wako. Kunyangwe mazinga eshuga yeropa ako akavandudzika zvakanyanya, izvi zvinogona kunge zviri nekuti mushonga uri kushanda, kwete nekuti hauchadi.

Chiremba wako angangofunga kuderedza kana kumisa saxagliptin kana wakaita shanduko huru muhupenyu hwako dzakavandudza kutonga kwako chirwere cheshuga, kana uri kusangana nemigumisiro inonetsa, kana kana vachida kuyedza imwe nzira yemishonga.

Vamwe vanhu vanogona kukwanisa kuderedza mishonga yavo yechirwere cheshuga kuburikidza nekurasikirwa kukuru uremu, kudya kwakavandudzwa, uye kurovedza muviri nguva dzose. Zvisinei, chisarudzo ichi chinofanira kugara chichiitwa pamwe chete nechikwata chako chehutano, nekutarisa zvakanyanya mazinga eshuga yeropa ako panguva yekuchinja kwemishonga.

Ndinganwa Doro Ndiri Kutora Saxagliptin?

Kunwa doro zvine mwero kunogamuchirwa zvakajairika uchi tora saxagliptin, asi unofanira kukurukura izvi nachiremba wako. Doro rinogona kukanganisa mazinga eshuga yeropa, uye kusanganiswa nemishonga yechirwere cheshuga kunoda kungwarira.

Kana ukasarudza kunwa doro, ita zvine mwero uye nguva dzose uchiita kudya. Doro rinogona kuderedza mazinga eshuga yeropa, kunyanya kana rakasanganiswa nemishonga yechirwere cheshuga, saka tarisa shuga yako yeropa zvakanyanya mumazuva aunonwa.

Ziva kuti doro rinogona kuvhara zviratidzo zvepasi shuga yeropa, zvichiita kuti zvive zvakaoma kuziva kana shuga yako yeropa ichidzika zvakanyanya. Kana uri kutora mimwe mishonga yechirwere cheshuga pamwe chete ne saxagliptin, njodzi yeshuga yakaderera yeropa nedoro inogona kunge yakakwira.