Chii chinonzi Secretin (Nzira yeIntravenous): Zvinoshandiswa, Dosage, Side Effects uye Zvimwe

Secretin mushonga wehormone we synthetic unopiwa kuburikidza ne IV unobatsira vanachiremba kuongorora matambudziko nepancreas yako uye gallbladder. Muviri wako unogadzira secretin pachisikigo mudumbu rako diki, asi vhezheni yekurapa yakagadzirwa zvakakosha kuti ikurudzire pancreas yako kuti ibudise majusi ekugaya kuti vanachiremba vaone kuti nhengo idzi dziri kushanda sei.

Mushonga uyu unonyanya kushandiswa panguva yekuedzwa kwekurapa kwakakosha, kwete sekurapa kwenguva dzose kwaungatora kumba. Funga nezvazvo sechishandiso chekuongorora chinobatsira timu yako yehutano kuwana mufananidzo wakajeka wehutano hwegadziriro yako yekugaya.

Chii chinonzi Secretin chinoshandiswa?

Secretin inoshanda semubatsiri wekuongorora kubatsira vanachiremba kuongorora kuti pancreas yako ne gallbladder yako inoshanda sei. Chinangwa chikuru ndechekukurudzira pancreas yako kuti ibudise uye ibudise ma enzymes ayo ekugaya uye mvura yakapfuma mu bicarbonate.

Vanachiremba vanowanzo shandisa secretin panguva yechirongwa chinonzi secretin-enhanced magnetic resonance cholangiopancreatography (MRCP). Zita iri rinoyevedza rinotsanangura MRI scan yakakosha inotora mifananidzo yakadzama yemabhairi ako uye pancreatic ducts. Kana secretin ikapiwa panguva yekuedzwa uku, inoita kuti zvivakwa izvi zviwedzere kuoneka pamifananidzo, zvichibatsira vanachiremba kuona mabhuroki, kuzvimba, kana mamwe matambudziko.

Vapi vehutano vanoshandisawo secretin kuyedza mamiriro anonzi Zollinger-Ellison syndrome. Chirwere ichi chisingawanzoitiki chinokonzera bundu mupancreas yako kana mudumbu diki rinoburitsa acid yakawandisa mudumbu. Iyo secretin test inogona kubatsira kusimbisa kuongororwa uku nekuyera kuti muviri wako unopindura sei kuhomoni.

Secretin inoshanda sei?

Secretin inoshanda nekutevedzera hormone yako yechisikigo inoudza pancreas yako kuti ibatikane. Paunodya, dumbu rako diki rinowanzo budisa secretin kuti riratidze pancreas yako kuti ibudise majusi ekugaya anobatsira kuputsa chikafu.

Mhando yekugadzirwa inoshanda basa rimwe chete asi munzvimbo inodzorwa, yekurapa. Mukati memaminitsi mashoma ekugamuchira jekiseni reIV, pancreas yako inotanga kuburitsa mvura yakajeka, alkaline yakapfuma mubicarbonate. Mvura iyi inobatsira kudzora acid yemudumbu uye ine ma enzymes anogaya mafuta, mapuroteni, uye makabhohaidhireti.

Mishonga iyi inoonekwa semushonga wekuongorora wepakati nepakati. Haina kunyanya kunaka semamwe madhayi ekusiyanisa, asi haina kusimba semishonga yechemotherapy zvakare. Mhedzisiro yacho inowanzoita yenguva pfupi uye inopera mukati memaawa mashoma sezvo muviri wako uchigadzirisa uye kubvisa hormone yekugadzirwa.

Ndingatora Sei Secretin?

Secretin inongopihwa nevashandi vehutano munzvimbo yekurapa kuburikidza nemutsara weintravenous (IV). Hauzotore mushonga uyu kumba kana kuzvipa iwe pachako.

Usati waita maitiro ako, chiremba wako anogona kukukumbira kuti utsanye kwemaawa 8 kusvika ku12. Izvi zvinoreva kuti hapana chikafu kana zvinwiwa kunze kwemvura shoma. Dumbu risina chinhu rinobatsira kuona kuti mhedzisiro yebvunzo ndeyechokwadi uye inoderedza njodzi yekunzwa kusvotwa panguva yemaitiro.

Panguva yebvunzo, mukoti kana tekiniki achaisa catheter diki reIV mutsinga muruoko rwako. Iyo secretin inobva yajekeswa zvishoma nezvishoma kuburikidza nemutsara uyu weIV. Unozofanira kurara wakanyarara panguva yekufananidza chikamu chebvunzo, iyo inowanzo tora maminitsi makumi matatu kusvika makumi matanhatu.

Mushure mekuwana secretin, unogona kunzwa kunzwa kudziya kana kureruka. Izvi zvakajairika uye zvinowanzoenda nekukurumidza. Chikwata chako chehutano chichakutarisa panguva yese yemaitiro kuti uone kuti unonzwa wakasununguka uye uchipindura zvakanaka kumushonga.

Ndingatora Secretin Kwenguva Yakareba Sei?

Secretin inoshandiswa kamwe chete pamaitiro ekuongorora, kwete sekurapa kuri kuenderera mberi. Mushonga unopihwa sejecction imwe chete inoshanda kwenguva yebvunzo yako.

Mhedzisiro ye secretin inowanzo gara maawa 2 kusvika ku4 mushure mejekiseni. Munguva iyi, pancreas yako icharamba ichigadzira mvura yekugaya iyo inobatsira vanachiremba kuti vaone zviri mukati memuviri wako zvakajeka pazvidzidzo zvekuongorora.

Kana uchida kudzokorora bvunzo mune ramangwana, chiremba wako anogona kuraira imwe nzira inowedzerwa secretin. Zvisinei, kazhinji hapana chikonzero chekuti uwane madosi akawanda panguva yebvunzo imwe chete kunze kwekunge zvichikurudzirwa zvakananga nachiremba wako.

Ndezvipi Zvakaipa zveSecretin?

Vanhu vazhinji vanotsungirira secretin zvakanaka, asi semushonga chero upi zvake, unogona kukonzera mhedzisiro yakaipa. Mashoko akanaka ndewekuti mhinduro dzakakomba hadziwanzowanikwi, uye mhedzisiro yakaipa yakawanda inenge iri nyoro uye yenguva pfupi.

Heano mhedzisiro yakaipa inowanzoitika yaungasangana nayo panguva kana nguva pfupi mushure mekuwana secretin:

• Kunyara kana kusagadzikana mudumbu
• Kunzwira kupisa kana kupisa kumeso kwako nemutsipa
• Kutadza musoro kana kunzwa uchinetseka
• Kuwedzera kwenguva pfupi kwemoyo
• Kutambudzika mudumbu rako

Mhedzisiro iyi inowanzo tanga mukati memaminitsi ekugamuchira jekiseni uye inowanzo pera mukati memaminitsi 30 kusvika ku60. Chikwata chako chehutano chichakutarisa zvakanyanya uye chinogona kupa zviyero zvekunyaradza kana zvichidikanwa.

Mhedzisiro yakaipa isingawanzoitiki asi yakakomba inogona kusanganisira mhinduro dzakakomba dzekurwara, kunyangwe izvi zvisingawanzoitiki. Zviratidzo zvekurwara kwakakomba zvinosanganisira kutadza kufema, kuzvimba kwakanyanya kumeso kwako kana pahuro, kuputika kwakapararira, kana kutadza musoro kwakanyanya. Kana chero izvi zvikaitika, chikwata chako chekurapa chichapindura nekukurumidza nekutarisirwa kwakakodzera.

Vamwe vanhu vanogona kusangana nekuderera kweropa mushure mekuwana secretin, izvo zvinogona kukonzera kunzwa kusimba kana kufenda. Ichi ndicho chikonzero nei uchizotarwa panguva yese yebasa uye kwenguva pfupi mushure.

Ndiani Asingafaniri Kutora Secretin?

Secretin haisi yakachengeteka kune munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akurudzira bvunzo iyi. Vanhu vane mamiriro akati wandei kana allergies vanofanira kudzivisa secretin kana kuishandisa nekuchenjerera kwakanyanya.

Haufaniri kugamuchira secretin kana uine allergy kune secretin pachayo kana chero chimwe chezvinhu zvayo. Kana wakambove nekuita kune mushonga uyu, ita shuwa kuti unoudza mupi wako wehutano usati waita chero maitiro.

Vanhu vane matambudziko emoyo akakomba, high blood pressure isingadzoreki, kana kurwisa kwemoyo kwemazuva ano vangave vasiri vakanaka vekuedzwa kwe secretin. Mushonga uyu unogona kukanganisa zvishoma nezvishoma kurova kwemoyo wako uye blood pressure, izvo zvinogona kuva njodzi kana uine matambudziko emoyo aripo.

Kana uri nepamuviri kana kuyamwisa, kurukura njodzi nemabhenefiti nachiremba wako. Kunyange secretin isina kuratidzwa kukuvadza vana vari kukura, inowanzo shandiswa chete kana ruzivo rwekuongorora rwakakosha kuhutano hwako.

Varwere vane chirwere cheitsvo kana chiropa chakakomba vangangoda kugadzirisa dose kana dzimwe nzira dzekuyedza. Nhengo idzi dzinobatsira kugadzirisa uye kubvisa mishonga mumuviri wako, saka matambudziko ane itsvo kana chiropa anogona kukanganisa mashandiro anoita secretin kana kuti inogara kwenguva yakareba sei mumuviri wako.

Mazita eSecretin Brand

Secretin inowanikwa pasi pezita remhando ChiRhoStim muUnited States. Iyi ndiyo fomu inonyanya kushandiswa ye synthetic secretin yekuongorora maitiro.

ChiRhoStim inogadzirwa zvakananga kushandiswa kwekurapa uye inouya seupfu hunosanganiswa nemvura yakachena isati yabayiwa. Mushonga uyu unowanikwa chete kuburikidza nevapi vehutano uye haugone kutengwa kuti ushandiswe kumba.

Zvimwe zvivakwa zvekurapa zvinogona kureva maitiro nemazita akasiyana, senge "secretin-enhanced MRCP" kana "secretin stimulation test," asi izvi zvese zvinowanzo shandisa mushonga mumwe chete.

Secretin Alternatives

Miedzo dzakawanda dzekuongorora mabasa epancreas dzinogona kushandiswa, kunyangwe imwe neimwe iine zvainobatsira nezvipingamupinyi zvayo. Chiremba wako achasarudza sarudzo yakanakisa zvichienderana nezviratidzo zvako uye nhoroondo yako yekurapa.

Endoscopic ultrasound (EUS) inopa mifananidzo yakadzama ye pancreas yako pasina kudiwa kwekusimudzira mahomoni. Iyi nzira inoshandisa chubhu yakatetepa, inochinjika ine ultrasound probe kuti iongorore pancreas yako kubva mukati memugwagwa wako wekudya.

Standard MRI kana CT scans inogonawo kuratidza kusagadzikana kwe pancreatic, kunyangwe isingape ruzivo rwakawanda nezve basa se secretin-enhanced studies. Miedzo iyi inowanzo shandiswa kana secretin isina kukodzera kana isingawanikwe.

Miedzo yeropa inoyera ma enzymes epancreatic senge lipase uye amylase inogona kuratidza matambudziko epancreatic, asi haipe ruzivo rwakadzama rwemaitiro ayo miedzo yekufungidzira inopa. Izvi zvinowanzo shandiswa senzira dzekutanga dzekutarisa.

Kune vanofungidzirwa Zollinger-Ellison syndrome, vanachiremba vanogona kushandisa mamwe miedzo yekusimudzira mahomoni kana kuyera mamwe mabhuku eropa panzvimbo pe secretin testing.

Ko Secretin Zviri Nani Pane Zvimwe Zviedzo Zvebasa rePancreatic?

Secretin-enhanced imaging inopa zvakanakira zvakasiyana zvinoita kuti ive sarudzo inofarirwa kune mamwe mamiriro ekuongorora. Bhenefiti huru ndeyekuti inopa ruzivo rwemaitiro uye rwemabasa nezve pancreas yako mumuedzo mumwe chete.

Kusiyana nemiedzo yakajairika yekufungidzira, secretin stimulation inoratidza kuti pancreas yako inoshanda sei, kwete kungoita sei. Ruzivo urwu rwemabasa rwakakosha pakuongorora mamiriro akaita se chronic pancreatitis, uko pancreas inogona kutaridzika zvakajairika asi isingashande zvakanaka.

Ichienzaniswa nemaitiro anopinda zvakanyanya se endoscopic retrograde cholangiopancreatography (ERCP), secretin-enhanced MRCP inotakura njodzi shoma. ERCP inosanganisira kuisa scope nemuromo wako mumugwagwa wako wekudya, uyo une njodzi yakakwirira yematambudziko akaita se pancreatitis kana kubuda ropa.

Asi, kuongorora secretin hakusi nguva dzose sarudzo yakanaka. Kune mamwe mamiriro, bvunzo dzemuviri dzakareruka kana mufananidzo wakajairika zvinogona kupa ruzivo rwakakwana. Chiremba wako achatarisa zviratidzo zvako, nhoroondo yako yezvokurapa, uye ruzivo rwakakosha runodiwa kuti uite kuongororwa kwakakodzera.

Mibvunzo Inowanzo Bvunzwa Pamusoro peSecretin

Secretin Yakachengeteka Here Kune Vanhu vane Chirwere cheShuga?

Secretin inowanzo chengeteka kune vanhu vane chirwere cheshuga, asi mazinga eshuga yeropa rako achada kuongororwa zvakanyanya panguva uye mushure mekuita. Mushonga unogona kukanganisa kwenguva pfupi kuti muviri wako unogadzirisa sei glucose.

Kana iwe uchitora mishonga yechirwere cheshuga, chiremba wako anogona kugadzirisa chirongwa chako chekushandisa mushonga wezuva rekuongorora, kunyanya sezvo uchizofanira kutsanya pamberi. Ita shuwa kuti ukurukure chirongwa chako chekugadzirisa chirwere cheshuga nechikwata chako chehutano pamberi pekuita.

Vanhu vane chirwere cheshuga chinodzorwa zvakanaka vanowanzo shivirira secretin pasina matambudziko. Zvisinei, kana shuga yako yeropa yanga isina kugadzikana munguva pfupi yapfuura, chiremba wako angada kumisa bvunzo kusvikira chirwere chako cheshuga chichigadziriswa zviri nani.

Ndoita Sei Kana Ndikagamuchira Secretin Yakawandisa Netsaona?

Secretin overdose haina kujairika zvakanyanya nekuti mushonga unongopihwa nevashandi vehutano vakadzidziswa munzvimbo dzekurapa dzakadzorwa. Dosing inoverengwa zvakanyatsoenderana nehuremu hwemuviri wako uye bvunzo chaiyo iri kuitwa.

Kana secretin yakawandisa yaipiwa netsaona, unogona kusangana nemigumisiro yakanyanya yakadai senausea yakanyanya, shanduko yakakosha yeropa, kana kurwadziwa kwepamuviri kwenguva refu. Chikwata chako chekurapa chaizopa rubatsiro rwekuchengetedza uye kukutarisa zvakanyanya.

Mashoko akanaka ndewekuti secretin inogadziriswa uye inobviswa mumuviri wako nekukurumidza, saka kunyangwe overdose ikaitika, mhedzisiro yaizova yenguva pfupi. Vapi vehutano vako vane mishonga uye kurapwa zviripo kuti vagadzirise chero maitiro akakomba.

Ndoita Sei Kana Ndikarasikirwa neDose yeSecretin?

Mubvunzo uyu haushande zvakanyanya kune secretin sezvo isiri mushonga waunotora nguva dzose kumba. Secretin inongopiwa kamwe chete panguva yezvinhu zvakakosha zvekuyera zvirwere muzvipatara.

Kana ukasaenda kumusangano wako wakarongeka wekuyedzwa kwe secretin, ingofonera hofisi yachiremba wako kuti urongezve. Hapana njodzi mukunonotsa bvunzo kwemazuva mashoma kana mavhiki, kunze kwekunge uine zviratidzo zvakakomba zvinoda kuongororwa nekukurumidza.

Chiremba wako achakuzivisa kuti bvunzo inofanira kupedzwa nekukurumidza sei zvichienderana nemamiriro ako ezvinhu chaiwo. Muzviitiko zvakawanda, kuronga zvakare hakuzokanganisi kururama kwemigumisiro kana chirongwa chako chekurapa.

Ndingamira Rini Kutora Secretin?

Haufaniri kunetseka nezvekumira kutora secretin nekuti haisi mushonga unopfuurira. Mhedzisiro yacho inopera zvakasikwa mukati memaawa mashoma mushure mejekiseni rimwe chete rinopiwa panguva yekuongorora kwako.

Muviri wako uchabvisa mahomoni ekugadzira kuburikidza nematsvo ako nechiropa, sekungobata mamwe mishonga. Hapana tapering kana kuderedzwa zvishoma nezvishoma kunodiwa.

Kana iwe uchida kuongororwa kutevera mune ramangwana, maitiro ega ega e secretin anobatwa sechinhu chakasiyana, chimwe chete. Hapana mhedzisiro yekuwedzera kana chikonzero chekufunga nezve zvikamu zvakapfuura pakuronga bvunzo dzemangwana.

Ndingatyaira Here Mushure meKugamuchira Secretin?

Vanhu vazhinji vanogona kutyaira mushure mekutambira secretin, asi unofanira kumirira kusvikira chizuru kana lightheadedness zvachose zvapera. Mushonga unogona kukanganisa zvishoma kumanikidzwa kweropa rako uye kurova kwemoyo, izvo zvingakuitira kuti usagadzikane.

Ronga kugara panzvimbo yekurapa kwemaminitsi angangoita 30 mushure mekuita kwako kuitira kuti vashandi vagone kuona kuti uri kunzwa wakagadzikana uye wakangwarira. Kana iwe uine chero chizuru chinoramba chiripo, kusvotwa, kana kusava nesimba, ronga kuti mumwe munhu akutyairire kumba.

Vamwe vanhu vanonzwa vaneta mushure mekuvhiyiwa, kunyanya kana vaifanira kutsanya zvisati zvaitika kana kana bvunzo yacho yaive inonetsa. Teerera muviri wako uye usazeze kukumbira rubatsiro rwekufambisa kana usinganzwe zvakajairika zvachose.