Chii chinonzi Tafenoquine: Zvayinoshandiswa, Mishonga, Zvinokonzera uye Zvimwe

Tafenoquine mushonga unotorwa nemurairo wekurwisa marariya unobatsira kudzivirira nekurapa zvirwere zvemarariya. Mushonga uyu mutsva unopa sarudzo ine simba yekudzivirira marariya paunenge uchifamba kuenda kunzvimbo dzine njodzi kana uchida kurapwa kwezvirwere zvemarariya zvakasiyana.

Sechikamu cheboka remishonga inonzi 8-aminoquinolines, tafenoquine inoshanda zvakasiyana nemimwe mishonga yakawanda ye marariya. Inotarisa parasite pazvikamu zvakawanda zvehupenyu hwayo, zvichiita kuti ive inobatsira zvikuru pakudzivirira nekurapa marariya zvakakwana.

Chii chinonzi Tafenoquine?

Tafenoquine mushonga wekurwisa marariya unodzivirira nekurapa marariya inokonzerwa nePlasmodium parasites. Iyo ndeyeboka remishonga inonzi 8-aminoquinolines, iyo inozivikanwa nekugona kwavo kubvisa marariya parasites kubva mumuviri wako zvachose.

Mushonga uyu wakabvumirwa neFDA muna 2018 uye unomiririra kufambira mberi kukuru mukurapa marariya. Kusiyana nemimwe mishonga yekare yekurwisa marariya, tafenoquine inogona kutarisisa parasites dzakavanda dzakavanda muchiropa chako, kudzivirira zvikamu zvemarariya mune ramangwana.

Mushonga uyu unouya semapiritsi anotorwa nemuromo uye anowanikwa chete nemurairo. Chiremba wako achasarudza kana tafenoquine yakakunakira zvichienderana nemamiriro ako chaiwo uye nhoroondo yako yekurapa.

Chii chinonzi Tafenoquine chinoshandiswa?

Tafenoquine inoshanda zvinangwa zviviri zvikuru mukuchengetwa kwemarariya: kudzivirira nekurapa. Chiremba wako angakupa mushonga uyu kuti akudzivirire kubva pakutapukirwa nemarariya kana kurapa chirwere chiripo.

Pakudzivirira, tafenoquine inoshanda seprophylaxis ye marariya paunenge uchifamba kuenda kunzvimbo dzemarariya akajairika. Inobatsira zvikuru panguva refu kana paunoda dziviriro yakawedzerwa mushure mekudzoka kumba.

Mushonga uyu unoshandiswawo kurapa Plasmodium vivax marariya, rudzi rwakati rwunogona kukonzera zvirwere zvinodzokororwa. Hezvino apo chiremba wako angakurudzira tafenoquine:

• Kudzivirira marariya panguva yekufamba kuenda kunzvimbo dzine marariya
• Kurapa zvirwere zvemarariya zveP. vivax zvakasimbiswa
• Kudzivirira kudzoka kwemarariya kubva kumaparasite echiropa akarara
• Mushonga wekudzivirira mushure mekufamba mushure mekuwanda kwekutarisana

Mupi wako wehutano achafunga nezve zvirongwa zvako zvekufamba, nhoroondo yako yezvokurapa, uye njodzi dzemarariya dzakatarwa munzvimbo yaunoenda paachasarudza kana tafenoquine yakakodzera kwauri.

Tafenoquine Inoshanda Sei?

Tafenoquine inofungidzirwa semushonga wemarariya une simba unoshanda nekutarisana nemaparasite emarariya pamatanho akasiyana ehupenyu hwavo. Inokanganisa kugona kweparasite kurarama nekubereka mumuviri wako.

Mishonga iyi inonyanya kushanda nekuti inogona kubvisa hypnozoites, ayo ari mafomu akarara eparasite yerariya anovanda muchiropa chako. Aya maparasite akarara anogona kumutsazve masvondo kana mwedzi gare gare, zvichikonzera zviitiko zvemarariya zvinodzokorora.

Nekutarisana nemaparasite anoshanda uye akarara, tafenoquine inopa dziviriro yakazara. Mushonga unokanganisa maitiro ecellular eparasite, pakupedzisira zvichitungamira mukuparadzwa kwavo uye kuvadzivirira kubva pakukonzera kurwara.

Ndinofanira Kutora Sei Tafenoquine?

Tora tafenoquine sezvinorayirwa nachiremba wako, kazhinji uine chikafu kuderedza dumbu. Mushonga unofanirwa kutorwa negirazi rakazara remvura panguva kana mushure mekudya.

Kudzivirira marariya, iwe unowanzo tora piritsi rimwe pavhiki, kutanga 1-2 mavhiki usati wafamba uye uchienderera mberi kwevhiki rimwe mushure mekudzoka. Chiremba wako achakupa mirairo chaiyo yenguva zvichienderana nezvirongwa zvako zvekufamba.

Pakurapa marariya, chirongwa chekuyera chinogona kunge chakasiyana uye kazhinji chinosanganisira kutora mushonga zuva rega rega kwenguva pfupi. Heano matungamiri akakosha ekutevera:

• Torai pamwe chete nechikafu kana mukaka kuti muvandudze kunyudzwa uye kuderedza kusvotwa
• Momedzai mahwendefa ese nemvura yakawanda
• Torai panguva imwe chete zuva rega rega kuti muve nemazinga akaenzana
• Musapwanye, kutsenga, kana kupatsanura mahwendefa
• Rambai muchitora kunyange mukanzwa zviri nani

Kana muine dambudziko rekumedza mahwendefa, taurai nachiremba wenyu nezvemimwe mishonga. Musamboshandura dose yenyu pasina kutungamirirwa nachiremba, sezvo izvi zvinogona kukanganisa kushanda kwemushonga.

Ndinofanira Kutora Tafenoquine Kwenguva Yakareba Sei?

Kureba kwemushonga we tafenoquine kunoenderana nekuti muri kuishandisa kudzivirira kana kurapa. Chiremba wenyu achakupa mirairo yakatarwa zvichienderana nemamiriro enyu ega ega.

Kudzivirira malaria panguva yekufamba, munowanzo tora tafenoquine kwenguva yechikamu chenyu pamwe chete nenguva yakawedzerwa musati maenda uye mushure. Izvi zvinowanzoita kuti mutange 1-2 mavhiki musati maenda uye muchienderera mberi kwevhiki rimwe mushure mekudzoka kumba.

Pakurapa hutachiona hwe malaria hunoshanda, nzira yacho inowanzoita ipfupi asi inowedzera. Kureba kwekurapa kunogona kubva kumazuva mashoma kusvika kumavhiki akati wandei, zvichienderana nerudzi rwe malaria uye mhinduro yenyu kumushonga.

Musambomira kutora tafenoquine nekukurumidza, kunyange mukanzwa zvakanaka zvachose. Kurapa kusina kukwana kunogona kukonzera hutachiona hunodzoka kana kuramba kwemishonga, zvichiita kuti malaria remangwana rive rakaoma kurapa.

Ndezvipi Zvakaipa ZveTafenoquine?

Semishonga yese, tafenoquine inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anoiziva. Mazhinji emhedzisiro idiki uye inogoneka, asi mamwe anogona kuve akakomba.

Mhedzisiro yakajairika iyo vanhu vazhinji vanoona inosanganisira kusvotwa, kurutsa, uye kusagadzikana mudumbu. Nyaya idzi dzekugaya dzinowanzoita nani kana muchitora mushonga pamwe chete nechikafu.

Heano mhedzisiro inonyanya kuziviswa yaungave uchiita:

• Kunyara nekutsvuka
• Kurwadziwa mudumbu kana mumatumbu
• Musoro
• Dizziness
• Kuneta kana kushaya simba
• Kutadza kurara
• Kushaya chido chekudya

Zvimwe zvinokonzera zvinogona kuitika, kunyanya muvanhu vane mamwe mamiriro emagene. Izvi zvinosanganisira anemia yakakomba, zviratidzo zvepfungwa zvakaita sekushushikana kana kuora mwoyo, uye shanduko dzemoyo.

Zvisingawanzoitiki asi zvakakomba zvinokonzeresa zvinoda kutariswa kwekurapa nekukasira zvinosanganisira maitiro akakomba ekuita allergic, kurutsa kusingaperi, kuneta kusinganzwisisike, kuita yero yeganda kana maziso, uye shanduko dzakakosha dzemafungiro. Bata chiremba wako nekukasira kana ukaona chero zviratidzo zvinonetsa.

Ndiani Asingafaniri Kutora Tafenoquine?

Tafenoquine haina kuchengeteka kune vese, uye vamwe vanhu vanofanirwa kudzivisa mushonga uyu zvachose. Chiremba wako achakutarisai kuti muone mamiriro chaiwo musati makanyorerwa tafenoquine.

Vanhu vane G6PD kushomeka, mamiriro emagene anokanganisa maseru matsvuku eropa, havafaniri kutora tafenoquine. Mushonga uyu unogona kukonzera anemia yakakomba muvanhu vane mamiriro aya, izvo zvinogona kuisa hupenyu panjodzi.

Musati makanyorerwa tafenoquine, chiremba wako anogona kuraira bvunzo yeropa kuti aone G6PD kushomeka. Heano mamwe mamiriro apo tafenoquine ingasava yakakodzera:

• Kuzivikanwa G6PD kushomeka
• Kukomba kweitsvo kana chiropa chirwere
• Nhoroondo yezvirwere zvepfungwa
• Kuzvitakura kana kuyamwisa
• Mamwe matambudziko emoyo
• Maitiro akakomba ekuita allergic kumishonga yakafanana

Chiremba wako achanyatsoongorora nhoroondo yako yekurapa uye anogona kuraira mamwe maedzo kuti ave nechokwadi chekuti tafenoquine yakachengeteka kwauri. Nguva dzose udza mupi wako wehutano nezve mishonga yese yaunotora uye chero mamiriro ekurapa aunayo.

Mazita eTafenoquine Brand

Tafenoquine inowanikwa pasi pezita rekuti Arakoda yekudzivirira malaria uye Krintafel yekurapa malaria. Zvose zvine chinhu chimwe chete chinoshanda asi zvinogona kuva nemarongerwo akasiyana ekushandisa.

Arakoda inobvumirwa zvakananga kudzivirira malaria muvanhu vakuru vanofamba vachienda kunzvimbo dzakajairika malaria. Krintafel inoshandiswa pamwe chete nemimwe mishonga inorwisa malaria kurapa P. vivax malaria.

Chiremba wako achanyora zita rakakodzera zvichienderana nekuti unoda kudzivirira kana kurapwa. Zvose zvinoda mushonga uye zvinofanira kushandiswa chete pasi pekutariswa kwechiremba.

Zvimwe Zvinogona Kushandiswa Pane Tafenoquine

Mishonga yakati wandei inorwisa malaria inowanikwa kana tafenoquine isingakukodzere. Chiremba wako anogona kukurudzira zvimwe zvinhu zvichienderana nezvido zvako zvakakosha uye nhoroondo yako yekurapa.

Zvimwe zvinhu zvinowanzo shandiswa kudzivirira malaria zvinosanganisira atovaquone-proguanil (Malarone), doxycycline, uye mefloquine. Imwe neimwe ine mabhenefiti akasiyana uye mhedzisiro.

Pakurapa malaria, zvimwe zvingasanganisira chloroquine, artemisinin-based combination therapies, kana primaquine. Sarudzo inoenderana nerudzi rwe malaria, kwaunogara, uye maitiro ekuramba emuno.

Mupi wako wehutano achafunga nezvezvinhu zvakaita sekwauri kuenda, nguva yerwendo, nhoroondo yekurapa, uye mimwe mishonga paanenge achisarudza sarudzo yakanakisa yekurwisa malaria kwauri.

Ko Tafenoquine Ari Nani Kudarika Primaquine Here?

Tafenoquine ne primaquine zvose zvinorwisa malaria zve8-aminoquinoline, asi tafenoquine inopa zvimwe zvakanakira pamusoro pe primaquine. Chinhu chikuru ndechekuti tafenoquine inoda madosi mashoma nekuda kwemigumisiro yayo inogara kwenguva refu mumuviri wako.

Nepo primaquine inowanzo daidza kushandiswa zuva nezuva kwemazuva gumi nemana, tafenoquine inogona kupiwa dose imwe chete kana pfupi. Izvi zvinoita kuti zvive nyore kupedzisa kurapwa uye zvinoderedza njodzi yekurasikirwa nemadosi.

Mishonga yese miviri ine njodzi dzakafanana, kunyanya kune vanhu vane G6PD kushomeka. Zvisinei, nguva refu yekushanda kwe tafenoquine zvinoreva kuti inogara mumuviri wako kwenguva refu, izvo zvinogona kuva zvakanakira uye kunetseka.

Chiremba wako achafunga nezve mamiriro ako chaiwo, kusanganisira kugona kwako kutora mishonga yezuva nezuva uye njodzi dzako, pakusarudza pakati pezvisarudzo izvi.

Mibvunzo Inowanzo Bvunzwa Nezve Tafenoquine

Tafenoquine Yakachengeteka Kune Vanhu Vane Chirwere Chemoyo Here?

Tafenoquine inogona kukanganisa rhythm yemoyo kune vamwe vanhu, saka inoda kufungwa zvakanyanya kana uine chirwere chemoyo. Chiremba wako achaongorora mamiriro ako chaiwo emoyo uye anogona kuraira mamwe maedzo asati anyora mushonga uyu.

Kana uine nhoroondo yematambudziko erhythm yemoyo, mupi wako wehutano angangokurudzira mamwe mishonga yekurwisa malaria. Nguva dzose kurukura nhoroondo yako yakazara yemoyo nachiremba wako usati watanga tafenoquine.

Ndoita Sei Kana Ndikatora Tafenoquine Yakawandisa Netsaona?

Kana netsaona ukatora tafenoquine yakawandisa, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira. Kutora zvakawanda kupfuura zvakarairwa kunogona kuwedzera njodzi yako yemigumisiro yakakomba, kunyanya kana uine G6PD kushomeka.

Usayedze kuzvirapa iwe pachako. Tsvaga rubatsiro rwekurapa rwehunyanzvi nekukasira, kunyangwe ukaita zvakanaka. Uya nebhodhoro remushonga newe kubatsira vanopa hutano kunzwisisa zvawakatora uye zvakawanda sei.

Ndoita Sei Kana Ndikakanganwa Dose ye Tafenoquine?

Kana ukakanganwa dose ye tafenoquine, itore paunorangarira, kunze kwekunge yava nguva yechikamu chako chinotevera. Usatore zvikamu zviviri panguva imwe chete kuti ugadzirise dose yakarasika.

Kuti udzivise, kana ukakanganwa dose yevhiki, itore nekukasira sezvinobvira wobva watora chirongwa chako chesevhisi. Taura nachiremba wako kana ukakanganwa zvikamu zvakawanda, sezvo izvi zvinogona kukanganisa dziviriro yako kubva kumalaria.

Ndingamira Rini Kutora Tafenoquine?

Regai kumwa tafenoquine chete kana chiremba wako akuudza, kunyangwe ukanzwa zvakanaka zvachose. Kumira kutanga kunogona kukonzera kutadza kurapa kana hutachiona hwe malaria hunodzoka.

Kuti udzivise, unozofanira kuramba uchitora tafenoquine kwenguva yakatarwa yese, kusanganisira mushure mekudzoka kubva parwendo. Kuti urapwe, pedzisa nzira yese sezvakarairwa kuti uve nechokwadi chekuti maparasite ese abviswa.

Ndinganwe Doro Ndiri Kumwa Tafenoquine Here?

Zvakanaka kuderedza kunwa doro uchitora tafenoquine, sezvo zvese zviri zviviri zvinogona kukanganisa chiropa chako uye zvinogona kuwedzera mhedzisiro. Doro rinogonawo kuwedzera mhedzisiro yekugaya chikafu senausea uye dumbu rinogumbuka.

Kana ukasarudza kunwa, ita zvine mwero uye teerera kuti unonzwa sei. Taura nachiremba wako nezvekushandisa doro, kunyanya kana uine matambudziko echiropa kana kutora mamwe mishonga.