Chii chinonzi Tapinarof: Zvinoshandiswa, Dosage, Side Effects uye Zvimwe
Created at:1/13/2025
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Tapinarof mushonga mutsva wepamusoro unobatsira kurapa plaque psoriasis nekushanda zvakasiyana nemishonga yechinyakare. Ikirimu yaunoshandisa zvakananga kunzvimbo dzeganda dzakakanganiswa, uye ndeyeboka remishonga inonzi aryl hydrocarbon receptor agonists. Mushonga uyu unopa tariro kune vanhu vanoda imwe nzira yekirimu ye steroid kana vasina kubudirira nemamwe marapirwo e psoriasis.
Chii chinonzi Tapinarof?
Tapinarof ikirimu yepamusoro isiri-steroidal yakagadzirirwa kurapa plaque psoriasis muvanhu vakuru. Kusiyana nekirimu ye steroid iyo inogona kutetepa ganda rako nekufamba kwenguva, tapinarof inoshanda kuburikidza nemaitiro akasiyana zvachose asingatakuri njodzi dzenguva refu.
Mushonga uyu wakabvumidzwa neFDA muna 2022, zvichiita kuti ive imwe yesarudzo itsva iripo yekurapa psoriasis. Inobva kune imwe nzira yechisikigo inowanikwa mumabhakitiriya, asi vhezheni inoshandiswa mumushonga inogadzirwa mumalaboratories kuti ive nechokwadi chekuchena uye kushanda zvakanaka.
Iwe uchawana tapinarof ichiwanika se1% kirimu inouya mumachubhu ehukuru hwakasiyana. Kirimu ine chitarisiko chakapfava, chichena uye inopararira nyore paganda rako pasina kusiya residue ine mafuta.
Chii chinonzi Tapinarof chinoshandiswa?
Tapinarof inonyanya kushandiswa kurapa plaque psoriasis, iyo ndiyo yakajairika fomu ye psoriasis inobata mamirioni evanhu pasi rose. Plaque psoriasis inogadzira nzvimbo dzakakwirira, dzvuku dzakafukidzwa nemakwande esirivha anogona kuoneka chero kupi zvako pamuviri wako.
Mushonga uyu unoshanda zvakanaka kune mild kusvika pakati nepakati plaque psoriasis. Chiremba wako angakurudzira tapinarof kana uine psoriasis patches panzvimbo dzakaita semagokora ako, mabvi, ganda remusoro, kana dzimwe nhengo dzemuviri dzisina kupindura zvakanaka kune mamwe marapirwo.
Vamwe vanachiremba vanonyorawo tapinarof kana varwere vachida kudzivisa kushandisa ma steroid kwenguva refu. Sezvo isiri steroid, unogona kuishandisa kwenguva yakareba usinganetseki nezve kutetepa kweganda kana mamwe mativi emuviri ane chekuita ne steroid.
Tapinarof Inoshanda Sei?
Tapinarof inoshanda nekumisa chimwe chinhu chinonzi aryl hydrocarbon receptor mumaseru ako eganda. Iri receptor rinoshanda semuchinjiko unobatsira kudzora kuzvimba uye kukwidziridza kukura kwemaseru eganda akajairika.
Kana psoriasis ikawedzera, maseru ako eganda anowanda nekukurumidza uye anogadzira zvikamu zvakakora, zvine makwapa. Tapinarof inobatsira kuderedza kukura uku kwemaseru nekuderedza kuzvimba kunokonzera kutsvuka uye kutsamwa.
Mishonga iyi inoonekwa seyepakati nepakati asi yakapfava kupfuura akawanda ekurapa psoriasis. Zvinowanzo tora mavhiki akati wandei kuti aratidze mhedzisiro yayo yakazara, saka kushivirira kwakakosha paunotanga kurapwa uku.
Ndingashandisa Sei Tapinarof?
Shandisa tapinarof cream kamwe chete pazuva kunzvimbo dzeganda dzakakanganiswa, zviri nani panguva imwe chete zuva rega rega. Haufaniri kuitora nechikafu kana mvura sezvo ichishandiswa zvakananga paganda rako.
Heano maitiro ekushandisa tapinarof nemazvo:
- Geza maoko ako zvakakwana usati waisa kirimu
- Chenesa nzvimbo yeganda yakakanganiswa zvinyoro-nyoro uye uipukute yakaoma
- Isa rukoko rutete rwekirimu kuti uvhare zvikamu zvepsoriasis zvakakwana
- Pukuta kirimu zvinyoro-nyoro kusvikira yanyangarika muganda rako
- Geza maoko ako zvakare mushure mekushandisa kunze kwekunge uchirapa maoko ako
Unogona kushandisa tapinarof kune kusvika ku20% yenzvimbo yako yemuviri. Usashandise kirimu rakawanda kupfuura rinokurudzirwa, sezvo izvi zvisingazoiita kuti ishande nekukurumidza uye inogona kuwedzera njodzi yako yemigumisiro.
Kirimu rinoshanda zvakanyanya kana richishandiswa paganda rakachena, rakaoma. Haufaniri kudzivisa kudya chikafu chakati wandei kana kutora chero matanho akakosha nezvekudya sezvo tapinarof ichishandiswa topically.
Ndingashandisa Tapinarof Kwenguva Yakareba Sei?
Vanhu vazhinji vanoshandisa tapinarof kwemwedzi yakati wandei kuti vaone kuvandudzwa kukuru muzviratidzo zvavo zvepsoriasis. Zvidzidzo zvekurapa zvakaratidza kuti varwere vazhinji vakawana zvakanakira zvinooneka mushure memavhiki gumi nemaviri ekushandisa zuva nezuva.
Chiremba wako anogona kukurudzira kushandisa tapinarof kwemwedzi mitatu kusvika kumatanhatu kuti uipe nguva yekushanda nemazvo. Vamwe vanhu vangangoda kuishandisa kwenguva refu, zvichienderana nekuti ganda ravo rinopindura sei kurapwa.
Kusiyana nemakrimu e steroid anoda kuzorora kudzivirira mhedzisiro, tapinarof inogona kushandiswa nguva dzose kwenguva yakareba. Chiremba wako achatarisa kufambira mberi kwako uye anogona kugadzirisa chirongwa chako chekurapa zvichienderana nekuti ganda rako rinovandudzika sei.
Ndezvipi Zvakaipa zveTapinarof?
Vanhu vazhinji vanotsungirira tapinarof zvakanaka, asi semushonga chero upi zvake, unogona kukonzera mhedzisiro. Mashoko akanaka ndewekuti mhedzisiro yakakomba haisi yakajairika nekirasi iyi yekurapa.
Mhedzisiro yakajairika yaungasangana nayo inosanganisira:
- Kutsamwa kweganda kana kutsvuka panzvimbo yekushandisa
- Kukwenya kana kupisa paunotanga kushandisa
- Ganda rakaoma munzvimbo dzakabatwa
- Kupisa kwakapfava kunowanzoita nani nekufamba kwenguva
- Folliculitis (zvimedu zvidiki zvakatenderedza bvudzi follicles)
Mhedzisiro iyi inowanzoita nyoro uye inowanzoita nani sezvo ganda rako richijaira mushonga. Vanhu vazhinji vanowana kuti chero kutsamwa kwekutanga kunoderera mushure memavhiki mashoma ekutanga ekushandisa.
Mhedzisiro isingawanzoitiki asi yakakomba inogona kusanganisira maitiro akakomba ekuita allergic. Kana iwe ukasangana nekupararira kwemavanga, kuoma kufema, kana kuzvimba kwechiso chako, miromo, kana huro, tsvaga rubatsiro rwekurapa nekukurumidza.
Vamwe vanhu vanogona kukudziridza contact dermatitis, iyo inokonzera kutsamwa kweganda kukuru kupfuura zvakajairika. Izvi hazviwanzowanikwi asi zvinoda kumisa mushonga uye kubvunza chiremba wako kuti uwane dzimwe nzira dzekurapa.
Ndiani Asingafaniri Kutora Tapinarof?
Tapinarof haikodzeri munhu wese, kunyangwe vanhu vakuru vazhinji vane plaque psoriasis vanogona kuishandisa zvakachengeteka. Unofanira kudzivisa mushonga uyu kana uine allergic ku tapinarof kana chero zvinhu zviri mukirimu.
Vana vari pasi pemakore gumi nemasere havafaniri kushandisa tapinarof sezvo zvidzidzo zvisina kusimbisa kuchengeteka kwayo nekushanda kwavo muvarwere vevana. Vakadzi vane pamuviri vanofanira kukurukura njodzi nemabhenefiti nachiremba wavo vasati vashandisa mushonga uyu.
Vanhu vane mamwe mamiriro eganda anoita kuti vanyanye kunzwa kumishonga yepamusoro vangangoda kudzivisa tapinarof. Chiremba wako anogona kukubatsira kuona kana mushonga uyu wakakodzera mamiriro ako chaiwo.
Mazita eTapinarof Brand
Tapinarof inotengeswa pasi pezita rekuti Vtama muUnited States. Iri ndiro zita rimwe chete remhando iripo parizvino remushonga uyu, sezvo ichiri itsva kumusika.
Vtama ine 1% tapinarof sechikamu chayo chinoshanda. Kirimu inouya mumatepi e30-gram uye 60-gram, zvichienderana nekuti unoda kurapa nzvimbo yakawanda sei yeganda.
Mhando dzakajairika dze tapinarof hadzisati dziripo sezvo mushonga uchiri pasi pekudzivirirwa kwepatent. Izvi zvinoreva kuti Vtama ndiyo chete sarudzo yako yekuwana kurapwa kwe tapinarof izvozvi.
Zvimwe Zvinhu Zviri Kutsiva Tapinarof
Mishonga yakati wandei yepamusoro inogona kurapa plaque psoriasis kana tapinarof isingashande kwauri kana isina kukodzera. Zvimwe zvinotsiva izvi zvinoshanda kuburikidza nemaitiro akasiyana uye zvinogona kunge zviri sarudzo dziri nani zvichienderana nezvido zvako chaiwo.
Topical corticosteroids dzinoramba dziri dzakanyanya kunyorerwa kurapwa kwe psoriasis. Izvi zvinosanganisira mishonga yakaita se clobetasol, betamethasone, uye triamcinolone, iyo inoderedza kuzvimba nekukurumidza asi inoda kunyatso tarisa kushandiswa kwenguva refu.
Vitamin D analogues senge calcipotriene (Dovonex) inopa imwe sarudzo isiri steroid. Mishonga iyi inobatsira kujairika kukura kwemasero eganda uye inogona kushandiswa kwenguva refu pasina njodzi dzakabatana ne steroids.
Zvimwe zvinotsiva zvitsva zvinosanganisira roflumilast (Zoryve), rimwe mushonga wepamusoro usiri we steroid unoshanda nekudzivirira enzyme inonzi PDE4. Mushonga uyu wakabvumidzwa panguva imwechete se tapinarof uye unopa mabhenefiti akafanana.
Ko Tapinarof Ari Nani Kudarika Clobetasol?
Tapinarof na clobetasol vanoshanda zvakasiyana uye vane zvakanakira zvakasiyana zvichienderana nemamiriro ako ezvinhu. Clobetasol i steroid yepamusoro ine simba inoshanda nekukurumidza asi inotakura njodzi dzenguva refu.
Clobetasol inowanzo ratidza mhedzisiro mukati memazuva kusvika kumavhiki, nepo tapinarof inogona kutora mavhiki akati wandei kusvika kumwedzi kuti ishande zvizere. Zvisinei, clobetasol inogona kukonzera kuonda kweganda, mavanga, uye zvimwe zvinokonzeresa nekushandiswa kwenguva refu.
Tapinarof inopa mukana wekuchengeteka kushandiswa kwenguva refu pasina matambudziko ane hukama ne steroids ine simba. Inowanzoonekwa seiri nani yekuchengetedza kurapa kana psoriasis yako ichidzorwa.
Chiremba wako angakurudzira kutanga ne clobetasol kuti uwane rubatsiro rwekukurumidza, wobva watsvaga tapinarof yekutungamira kwenguva refu. Iyi nzira inobatanidza chiito chekukurumidza che steroids neiyo safety profile ye tapinarof.
Mibvunzo Inowanzo Bvunzwa Nezve Tapinarof
Ko Tapinarof Akachengeteka Here Kune Chirwere cheShuga?
Hongu, tapinarof inowanzochengeteka kune vanhu vane chirwere cheshuga sezvo ichishandiswa pamusoro uye haina kukanganisa zvakanyanya mazinga eshuga yeropa. Mushonga unoshanda munzvimbo paganda rako uye haukanganisi mishonga yechirwere cheshuga kana insulin.
Zvisinei, vanhu vane chirwere cheshuga vanofanira kutarisa ganda ravo zvakanyanya pavanenge vachishandisa chero mushonga mutsva wepamusoro. Chirwere cheshuga chinogona kunonotsa kupora kwemavanga uye kuwedzera njodzi yekutapukirwa, saka shuma chero shanduko dzisinganzwisisike dzeganda kuchiremba wako nekukurumidza.
Ndoita Sei Kana Ndikashandisa Tapinarof Yakawandisa Netsaona?
Kushandisa tapinarof yakawandisa dzimwe nguva hakuna njodzi, asi hazviite kuti mushonga ushande zviri nani. Ingo pukuta chero kirimu yakawandisa uye uenderere mberi neiyo yakajairika application routine zuva rinotevera.
Kana ukashandisa kirimu yakawanda nguva dzose, unogona kuona ganda rako richitsamwa kupfuura zvakajairika. Deredza huwandu hwaunoshandisa uye shandisa chete rukoko rutete runovhara nzvimbo dzakakanganiswa zvizere.
Ndingaita Sei Kana Ndakanganwa Kushandisa Tapinarof?
Kana ukakanganwa kushandisa tapinarof, shandisa pakarepo paunoyeuka pazuva rimwe chete. Usashandisa kirimu yakawanda zuva rinotevera kuti ugadzirise dose yakarasika.
Kukanganwa dose dzimwe nguva hakuzokukuvadzi, asi kushandisa zuva nezuva nguva dzose kunokupa mhedzisiro yakanaka. Funga nezvekuisa chiyeuchidzo chezuva nezuva pafoni yako kuti ikubatsire kuyeuka nguva yako yekushandisa.
Ndingamira Rini Kushandisa Tapinarof?
Unogona kumira kushandisa tapinarof kana chiremba wako aona kuti psoriasis yako yakadzorwa zvakanaka kana ukaona mhedzisiro inopfuura mabhenefiti. Usamira kamwe kamwe usina kutaurirana nechiremba wako kutanga.
Vamwe vanhu vangada kushandisa tapinarof kwenguva refu kuti vachengetedze ganda rakajeka, nepo vamwe vachigona kuchinjira kune imwe nzira yekurapa yekuchengetedza. Chiremba wako achakubatsira kugadzira nzira yakanaka yekugadzirisa psoriasis yako kwenguva refu.
Ndingashandisa Tapinarof pamwe chete nemamwe marapirwo ePsoriasis?
Tapinarof inogona kazhinji kusanganiswa nemamwe marapirwo epsoriasis, asi unofanirwa kutanga wataurirana nachiremba wako. Dzimwe nzira dzinoshanda zvakanaka pamwe chete, nepo dzimwe dzichigona kuwedzera njodzi yako yekutsamwa kweganda.
Chiremba wako anogona kukurudzira kushandisa tapinarof pamwe chete nemoisturizers, zvicheneso zvinyoro, kana kunyange mamwe mishonga yepamusoro. Vachakubatsira kugadzira chirongwa chekurapa chakazara chinowedzera mabhenefiti uchideredza mhedzisiro.