Chii chinonzi Teriparatide: Zvinoshandiswa, Dosage, Side Effects uye Zvimwe

Teriparatide imhando yekugadzirwa ye parathyroid hormone inobatsira kuvaka nyowani bone tissue mumuviri wako. Imushonga unopiwa nechiremba semujeko wezuva nezuva pasi peganda kurapa osteoporosis yakakomba kana mamwe marapirwo asina kushanda zvakanaka. Mushonga uyu unokosha zvikuru nokuti unokurudzira muviri wako kuti ugadzire mapfupa matsva, pane kungononotsa kurasikirwa kwemapfupa semamwe mishonga yakawanda ye osteoporosis.

Chii chinonzi Teriparatide?

Teriparatide ikopi yakagadzirwa nemunhu ye hormone iyo parathyroid glands yako inogadzira zvakasikwa kubatsira kudzora calcium uye hutano hwemapfupa. Parathyroid glands yako ndiyo mana madiki glands mumutsipa wako anoshanda pamwe chete nethyroid yako kuti mapfupa ako arambe akasimba uye mazinga ako e calcium akaringana. Kana magland aya akaburitsa parathyroid hormone mumaburst mapfupi, inoratidza masero ako ekuvaka mapfupa kuti atange kushanda.

Mushonga uyu unouya semvura yakajeka mune pre-filled pen injector yaunoshandisa kamwe chete pazuva. Kusiyana ne hormone yemuviri wako inoburitswa muzvinhu zvidiki zuva rese, teriparatide inokupa chiyero chinodzorwa chinonyanya kutariswa pakuumbwa kwemapfupa. Iyi nzira yakatarwa inoita kuti ive inonyanya kushanda kune vanhu vane mapfupa avo akava asina simba zvakanyanya.

Chii chinonzi Teriparatide chinoshandiswa?

Teriparatide inorapa osteoporosis yakakomba muvanhu vakuru vane njodzi huru yekutyora mapfupa. Chiremba wako anowanzo kupa mushonga uyu kana wakatotora mamwe marapirwo e osteoporosis pasina kubudirira zvakakwana, kana kana bvunzo dzako dzemapfupa dzichiratidza kuti mapfupa ako akapfava zvakanyanya. Zvinobatsira zvikuru kune vanhu vakambove nemapfupa kubva mukudonha kudiki kana mabasa ezuva nezuva.

Mushonga uyu unoshanda zvakanaka kuvakadzi vakapfuura menopause nevarume vane osteoporosis vanotarisana nenjodzi huru yekutyoka musana kana chiuno. Vamwe vanhu vanogashirawo teriparatide kana vakawana osteoporosis kubva mukushandisa steroid kwenguva refu, izvo zvinogona kuita kuti mapfupa asakare simba nekufamba kwenguva. Chiremba wako angangofungawo nezvekurapa uku kana uine zvinhu zvakawanda zvinokonzera kutyoka, zvakadai senhoroondo yemhuri ye osteoporosis, kutyoka kwakapfuura, kana mamwe mamiriro ezvinhu anokanganisa hutano hwemapfupa.

Teriparatide Inoshanda Sei?

Teriparatide inoshanda nekutevedzera maitiro emuviri wako ekuvaka mapfupa, asi nenzira yakatarwa uye ine simba. Paunobaya mushonga, inoshandisa maseru akakosha anonzi osteoblasts ayo ane basa rekugadzira nyama itsva yemapfupa. Funga nezvemaseru aya sevashandi vemuviri wako vanovaka nekugadzirisa chimiro chako chemapfupa.

Mushonga uyu unoonekwa sekurapa kwakasimba kwekuvaka mapfupa nekuti haingononotsi kurasikirwa kwemapfupa semamwe madhiragi e osteoporosis. Panzvimbo pezvo, inokurudzira zvakanyanya kuumbwa kwenyama itsva, ine hutano hwemapfupa uku ichivandudzawo mhando nesimba remapfupa aripo. Kubaya kwezuva nezuva kunopa dose yakanyanya iyo osteoblasts yako inogona kushandisa nekukasira kutanga basa ravo rekugadzirisa.

Vanhu vazhinji vanotanga kuona kuvandudzwa mukukora kwemapfupa avo mukati memwedzi mitanhatu yekutanga kurapwa. Mushonga uyu unoenderera mberi nekusimbisa mapfupa panguva yekurapa, iyo inowanzoita kusvika kumakore maviri. Mushure mekumisa teriparatide, chiremba wako anowanzo kurudzira kuchinja kune mumwe mushonga we osteoporosis kuti uchengetedze kuvandudzwa kwemapfupa awana.

Ndingatora Sei Teriparatide?

Muchinjika teriparatide kamwe chete pazuva, zviri nani panguva imwe chete zuva rega rega kuti zvikubatsire kuyeuka uye kuchengetedza mazinga akagadzikana mumuviri wako. Muchinjika unoenda munyama ine mafuta iri pasi peganda rako, kazhinji muzvidya zvako kana dumbu. Murapi wako wehutano achakudzidzisa nzira yakakodzera yekujova uye achakubatsira kusarudza nzvimbo dzakanakisa dzekujova dzekuchinjana pakati.

Unogona kutora mushonga uyu uine kana usina chikafu, asi vanhu vazhinji vanoona zvichibatsira kubatanidza nguva yavo yekujova nezuva nezuva senge kukwesha mazino avo kana kudya kwemangwanani. Iyo peni injector inoita kuti maitiro acho ave akareruka, uye vanhu vazhinji vanonyatsoita self-injection mukati memazuva mashoma. Chengeta mushonga wako mufiriji uye uregere kuuya kutembiricha yemumba kwemaminitsi mashoma usati wajova kuti zviite zvakanyanya kunaka.

Zvakakosha kugara pasi kana kurara pasi kwemadosi mashoma ekutanga nekuti vamwe vanhu vanonzwa dzungu kana musoro mushure mejekiseni. Izvi zvinowanzoita nani mushure memazuva mashoma ekutanga sezvo muviri wako uchigadzirisa kumushonga. Kana iwe uchinzwa usina kunaka mushure mejekiseni, zorora kwemaminitsi gumi nemashanu kusvika makumi maviri usati wamira kana kutangazve mabasa ako akajairika.

Ndingatora Teriparatide Kwenguva Yakareba Sei?

Vanhu vazhinji vanotora teriparatide kwemakore maviri, ndiyo nguva yakanyanya kurapwa inokurudzirwa yemushonga uyu. Muganho wenguva uyu uripo nekuti kurapwa kwenguva refu hakuna kudzidzwa zvakanyanya, uye mapfupa ako anowanzoita zvakanyanya kuvandudzwa mukati menguva iyi. Chiremba wako achatarisa kufambira mberi kwako nemiedzo yenguva dzose yekukora kwemapfupa kuti ateedzere kuti mushonga uri kushanda sei.

Mushure mekupedza kurapwa kwako kwe teriparatide, chiremba wako anogona kukutamisira kumushonga wakasiyana we osteoporosis kuti ubatsire kuchengetedza simba remapfupa raunowana. Pasina kurapwa kwekutevera, mabhenefiti e teriparatide anogona kudzikira zvishoma nezvishoma nekufamba kwenguva. Iyi nzira yekuchinja inokubatsira kuchengetedza shanduko dzakanaka uchivimbisa kuti mapfupa ako anoramba akachengetedzwa kwenguva refu.

Ndezvipi Zvipingamupinyi zveTeriparatide?

Semishonga yese, teriparatide inogona kukonzera zvipingamupinyi, kunyangwe vanhu vazhinji vachizvigamuchira zvakanaka kana muviri wavo wajaira. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakagadzirira uye kuziva nguva yekubata chiremba wako.

Zvipingamupinyi zvakajairika zvaungasangana nazvo zvinosanganisira:

• Kurwadziwa mudumbu, kunyanya mumavhiki mashoma ekutanga ekurapa
• Dizziness kana kunzwa lightheaded mushure mejekiseni
• Musoro unowanzoita nyoro uye wenguva pfupi
• Leg cramps kana kurwadziwa kwemhasuru
• Kurwadziwa kudiki kana kutsvuka panzvimbo yejekiseni
• Kuneta kana kunzwa kuneta kupfuura zvakajairika

Izvi zvipingamupinyi zvakajairika zvinowanzoita nani sezvo muviri wako uchijaira mushonga, kazhinji mukati memwedzi wekutanga wekurapa.

Vamwe vanhu vanogona kusangana nezvipingamupinyi zvakakomba zvinoda kutarisirwa kwekurapa nekukurumidza:

• Dizziness yakakomba kana fainting spells
• Kurwadziwa mudumbu kana kurutsa kunodzivirira kudya
• Zviratidzo zveakakwirisa calcium mazinga senge kuvhiringidzika, nyota yakanyanya, kana kuwanda kweweti
• Kurwadziwa kwemapfupa kusingajairiki kana nzvimbo nyowani dzekusagadzikana
• Allergic reactions yakakomba ine rash, kuzvimba, kana kuoma kufema

Kunyange zvichishamisa, vamwe vanhu vanogona kukudziridza osteosarcoma, rudzi rwegomarara remapfupa, kunyangwe izvi zvakaonekwa zvakanyanya muzvidzidzo zvemhuka nemadosi akakwirisa. Chiremba wako achakurukura njodzi iyi newe uye akubatsire kunzwisisa kuti inoshanda sei kumamiriro ako chaiwo.

Ndiani Asingafaniri Kutora Teriparatide?

Teriparatide haina kuchengeteka kune vese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa usati wairaira. Mamiriro akati wandei uye mamiriro anoita kuti mushonga uyu usakodzere kana kuita njodzi kune vamwe vanhu.

Haufaniri kutora teriparatide kana uine:

• Nhoroondo yegomarara remapfupa kana mamwe magomarara akapararira kumapfupa ako
• Chirwere chaPaget, chimiro chinokonzera kusagadzirika kwemapfupa
• Mazinga epamusoro ecalcium muropa rako
• Chirwere chakakomba cheitsvo
• Kurapa kwemwaranzi kwemapfupa ako kare
• Zvimwe zvirwere zvemapfupa zvemetabolic kupfuura osteoporosis

Chiremba wako achavawo akangwarira nezvekupa teriparatide kana iwe wakazvitakura, uchiyamwisa, kana uri pasi pemakore gumi nemasere, sezvo kuchengeteka mumamiriro ezvinhu aya kusina kumiswa.

Mukuwedzera, vanhu vane mamwe mamiriro emwoyo, matambudziko echiropa, kana avo vari kutora mishonga yakati wandei vanogona kuda kuongororwa kwakakosha kana mamwe marapirwo. Mupi wako wehutano achatarisa zvese izvi kuti aone kana teriparatide iri sarudzo yakakodzera yemamiriro ako ezvinhu.

Mazita eBrand eTeriparatide

Teriparatide inowanikwa pasi pezita rebrand Forteo munyika zhinji, kusanganisira United States. Iyi ndiyo vhezheni inonyanya kupihwa uye inouya mune pre-filled pen injector ine mazuva makumi maviri nemasere emushonga. Pen yakagadzirirwa kuti ive nyore kushandisa uye inobatsira kuona kuti unowana dose chaiyo nguva imwe neimwe.

Mune dzimwe nzvimbo, unogona zvakare kuwana teriparatide pasi pemamwe mazita ebrand kana semavhezheni ebiosimilar, ayo ari mishonga inenge yakafanana inoshanda nenzira imwechete. Murapi wako wemishonga anogona kukubatsira kunzwisisa kuti ndeipi vhezheni yaunogamuchira uye kuona kuti uri kushandisa nzira yekujekesa yakarurama yechishandiso chako chepeni.

Zvimwe Zvinhu zveTeriparatide

Kana teriparatide isiri yakakunakira, mamwe mishonga yeosteoporosis anogona kubatsira kusimbisa mapfupa ako. Chiremba wako angangofunga nezve bisphosphonates senge alendronate kana risedronate, iyo inoshanda nekumisa kuputsika kwemapfupa panzvimbo yekuvaka mapfupa matsva. Mishonga iyi inowanzoedzwa kutanga nekuti inotorwa nemuromo uye yave ichishandiswa zvakachengeteka kwemakore mazhinji.

Imwe nzira ndeye denosumab, jekiseni rinopiwa mwedzi mitanhatu yega yega iro rinononotsawo kurasikirwa kwemapfupa asi rinoshanda nenzira yakasiyana ne bisphosphonates. Kune vamwe vanhu, hormone replacement therapy kana selective estrogen receptor modulators zvingave zvakakodzera, kunyanya kuvakadzi vakapfuura menopause vanogona kubatsirwa nekudzivirirwa kwemapfupa ane hukama nehomoni.

Romosozumab mushonga mutsva uyo, kufanana ne teriparatide, unovaka chaizvo nyowani mapfupa. Inopiwa sejekiseni remwedzi nemwedzi kwegore rimwe uye inogona kufungwa kana iwe uchida kurapwa kwekuvaka mapfupa asi usingakwanise kutora teriparatide. Chiremba wako achakubatsira kuyera mabhenefiti nenjodzi dzeimwe neimwe sarudzo zvichibva pazvido zvako zvehutano.

Ko Teriparatide Zviri Nani Pane Zvimwe Zvinhu Zvekudzivirira Osteoporosis?

Teriparatide inopa zvakanakira zvakasiyana nekuti ndechimwe chezvinhu zvishoma zvinovaka mapfupa matsva panzvimbo yekungodzivirira kurasikirwa kwemapfupa. Izvi zvinoita kuti zvive zvakakosha kune vanhu vane osteoporosis yakakomba vanoda kusimbisa mapfupa avo nekukurumidza. Zvidzidzo zvinoratidza kuti teriparatide inogona kuwedzera zvakanyanya kuwanda kwemapfupa uye kuderedza njodzi yekutyoka nekukurumidza kupfuura dzimwe nzira dzakawanda dzekurapa.

Zvisinei,

Ko Teriparatide Yakachengeteka Here Kune Vanhu vane Chirwere Chemoyo?

Teriparatide inogona kushandiswa zvakachengeteka kune vanhu vane chirwere chemoyo, asi chiremba wako achada kukutarisa zvakanyanya. Vamwe vanhu vanowana kuwedzera kudiki kwemoyo kana ropa mushure mejekiseni, kunyanya panguva yekutanga mishoma. Kana uine matambudziko emoyo, chiremba wako angakurudzira kutanga nekutarisa kwakawanda kana kugadzirisa maitiro aunoita mushonga.

Chinhu chakakosha kugara kana kurara pasi kwemaminitsi gumi nemashanu kusvika makumi maviri mushure mejekiseni rega rega uye kudzivisa kufamba kamwe kamwe kunogona kukonzera dzungu. Vanhu vazhinji vane matambudziko emoyo vanotsungirira teriparatide zvakanaka kana muviri wavo wagadzirisa mushonga. Chiremba wako wemoyo uye endocrinologist vanogona kushanda pamwechete kuti vave nechokwadi chekuti kurapwa uku kunokodzera zvakachengeteka muhurongwa hwako hwese hwehutano hwemoyo.

Ndoitei Kana Ndikashandisa Zvakanyanya Teriparatide Netsaona?

Kana ukaisa jekiseni netsaona kupfuura chiyero chako chakatemwa, taura nachiremba wako kana wezve mishonga nekukasira kuti uwane gwara. Kutora teriparatide yakawandisa kunogona kukonzera mazinga ako ecalcium kukwira zvakanyanya, izvo zvingakonzera kuti unzwe kusvotwa, kuvhiringidzika, kana kunzwa nyota zvakanyanya. Usaedze kutsiva nekusvetuka chiyero chako chinotevera kunze kwekunge mupi wako wehutano achikuudza zvakananga kuti uite kudaro.

Majekiseni mazhinji epens anogadzirirwa kudzivirira overdoses netsaona, asi kana iwe uchifunga kuti wakagamuchira mushonga wakawandisa, zvinogara zviri nani kutarisa nechikwata chako chekurapa. Vanogona kukupa zano pamusoro pezviratidzo zvekutarisa uye kana iwe uchida chero bvunzo dzekutarisa mazinga ako ecalcium. Chengeta kurongedza kwemushonga newe paunofona kuti ugone kupa ruzivo rwakajeka nezve zvakaitika.

Ndoitei Kana Ndikarasikirwa neDose yeTeriparatide?

Kana ukakanganwa mushonga, tora paunorangarira, kunze kwekunge yava nguva yekutora mushonga unotevera. Kana zvakadaro, siya mushonga wakakanganwa wotora mushonga wako wenguva dzose zuva rinotevera. Usambofa wakatora mishonga miviri panguva imwe chete kuti ugadzirise mushonga wakakanganwa, sezvo izvi zvinogona kuwedzera njodzi yako yekuwana mhedzisiro yakaipa.

Edza kuchengetedza maitiro ako ezuva nezuva sezvinobvira, asi usanetseka kana ukakanganwa mushonga dzimwe nguva. Kukanganwa mushonga mumwe kana miviri hakuzokanganisi kufambira mberi kwekurapa kwako zvakanyanya. Vamwe vanhu vanoona zvichibatsira kumisa alarm yezuva nezuva kana kubatanidza nguva yavo yekujekesa kune imwe chiitiko chezuva nezuva kuti vabatsire kurangarira. Kana uchikanganwa mishonga kakawanda, taura nachiremba wako nezve nzira dzekukubatsira kuti urambe uri munzira.

Ndingamira Rini Kutora Teriparatide?

Unowanzo mira kutora teriparatide mushure memakore maviri, ndiyo nguva yakareba yekurapa inokurudzirwa. Zvisinei, chiremba wako anogona kukurudzira kumira kare kana ukaona mhedzisiro yakaipa inodarika mabhenefiti, kana bvunzo dzako dzekukora kwemapfupa dzichiratidza kuvandudzwa kukuru, kana kana mamwe mamiriro ehutano achiita kuti kuramba kurapwa kusina njere.

Usamira kutora teriparatide wega usina kutaurirana nachiremba wako kutanga. Kumira kamwechete hakuzokonzeri zviratidzo zvinotyisa zvekubvisa, asi iwe ucharasikirwa nemabhenefiti ekuvaka mapfupa nekufamba kwenguva pasina kurapwa kunotevera. Chiremba wako anowanzo kuronga shanduko kune rimwe mushonga we osteoporosis usati wapedza kosi yako ye teriparatide kuti ubatsire kuchengetedza kuvandudzwa kwawakawana.

Ndingafamba NeTeriparatide Here?

Hongu, unogona kufamba ne teriparatide, asi uchada kuronga mberi kuti uchengetedze mushonga wacho zvakanaka uye kubata zvinodiwa zvekuchengetedza zvengarava. Tora mushonga wako mumutoro wako wekufambisa panzvimbo yemabhegi akaongororwa kudzivirira kutonhora kana kupisa kwakanyanya. Uya netsamba kubva kuna chiremba wako ichitsanangura kudiwa kwako kwemushonga unojekeswa uye masirinji.

Pakuenda rwendo rurefu, ungada kutora chifiriji chidiki kana bhegi rine insulation rine ice packs kuti uchengetedze tembiricha yakakodzera. Mabhuruku mazhinji anotengesa mabhokisi ekufambisa akagadzirirwa mishonga inojekeswa. Kana uri kufamba uchipfuura nzvimbo dzenguva, edza kuchengetedza chirongwa chako chekushandisa mushonga chemaawa makumi maviri nemana sezvinobvira, uye usanetseka kana uchida kugadzirisa neawa kana maviri kuti zvienderane netsika yako itsva.