Chii chinonzi Terlipressin: Zvayakashandiswa, Madosi, Migumisiro Yakaipa nezvimwe

Terlipressin mushonga une simba we synthetic hormone unopiwa kuburikidza nemutsara we IV muzvipatara kurapa mamiriro anotyisa ehupenyu anosanganisira kudzikira kwakanyanya kweropa. Mushonga uyu unoshanda nekusimbisa tsinga dzeropa mumuviri wako wese, uchibatsira kudzorera kuyerera kweropa kwakajairika kana hurongwa hwako hwemoyo huri munjodzi.

Iwe unowanzoona terlipressin mumayuniti ekuchengetedza akanyanya kana madhipatimendi ekukurumidzira, uko zvikwata zvekurapa zvinoshandisa sekuvhiya kwakakosha. Mushonga unoda kunyatso tariswa nekuda kwemigumisiro yawo ine simba pahurongwa hwako hwekufambisa ropa.

Chii chinonzi Terlipressin?

Terlipressin ishanduro ye synthetic ye vasopressin, hormone iyo muviri wako unogadzira zvakasikwa kubatsira kudzora ropa uye chiyero chemvura. Mushonga uyu ndewechikamu chemishonga inonzi vasopressors, zvinoreva kuti inosimbisa tsinga dzeropa kuti iwedzere ropa.

Muviri wako unowanzoita vasopressin mu hypothalamus yeuropi hwako, asi panguva yekukurumidzira kwakanyanya kwekurapa, unogona kuda huwandu hwakawanda kupfuura muviri wako unogona kugadzira. Ndipo panopinda terlipressin sekuvhiya kwekurapa.

Mushonga uyu unoonekwa sevasopressor yakasimba, zvinoreva kuti ine simba rakakura pahurongwa hwako hwemoyo. Nekuda kwesimba rayo, vanachiremba vanongoi shandisa muzvipatara uko vanogona kunyatso tarisa mhinduro yako.

Chii chinonzi Terlipressin chinoshandiswa?

Terlipressin inorapa mamiriro maviri makuru anotyisa ehupenyu: hepatorenal syndrome uye septic shock ine kudzikira kwakanyanya kweropa. Mamiriro ese ari maviri anosanganisira kusakwanisa kwemuviri wako kuchengetedza ropa rakakwana uye basa remuviri.

Mu hepatorenal syndrome, chirwere chako chechiropa chakafambira mberi kusvika padanho apo itsvo dzako dzinotanga kutadza nekuda kwekuyerera kweropa kushoma. Izvi zvinogadzira kutenderera kunotyisa uko chepfu inovaka mumuviri wako apo nhengo dzako hadziwani ropa rakakwana rine okisijeni.

Pamusoro pe septic shock, terlipressin inobatsira kana muviri wako uchipindura kune hutachiona zvichikonzera kuti tsinga dzeropa dzizorore zvakanyanya zvekuti ropa rako rinoderera kusvika panjodzi. Mamiriro aya anogona kukurumidza kutungamira kukukundikana kwenhengo kana zvisina kurapwa nekukurumidza.

Dzimwe nguva vanachiremba vanoshandisawo terlipressin kubuda ropa rakanyanya mu esophagus yako rinokonzerwa netsinga dzakakura, mamiriro anonzi esophageal varices. Mushonga unobatsira kuderedza kuyerera kweropa kunzvimbo idzi dzine matambudziko.

Terlipressin Inoshanda Sei?

Terlipressin inoshanda nekubatanidza kune zvakakosha zvinogamuchira mumadziro etsinga dzeropa rako, zvichikonzera kuti dzibvumirane uye dzidzikiswe. Chiito ichi chinowedzera kuramba mumuviri wako wekutenderera, izvo zvinobatsira kusundira ropa rako kumusoro kumatanho akachengeteka.

Mushonga unokanganisawo itsvo dzako nekugadzirisa kuyerera kweropa kunhengo idzi dzakakosha. Kuyerera kweropa kwakanaka kwetsvo kunobatsira muviri wako kubvisa chepfu zvinobudirira uye kuchengetedza chiyero chemvura chakakodzera.

Kusiyana nemamwe ma vasopressors, terlipressin ine mhedzisiro inogara kwenguva refu mumuviri wako. Izvi zvinoreva kuti vanachiremba havafaniri kuipa kazhinji, asi zvinorevawo kuti mhedzisiro inotora nguva yakareba kuti ipere kana kurapwa kwapera.

Uyu mushonga une simba unokanganisa zvakanyanya muviri wako wemoyo. Mhedzisiro ine simba inoita kuti ive inobudirira mumamiriro ezvinhu akakosha asi inodawo kutarisirwa kwakanyanya kwekurapa.

Ndingatora Sei Terlipressin?

Haugone kutora terlipressin nemuromo kana kuzvipa iwe pachako kumba. Mushonga uyu unongopihwa chete kuburikidza ne IV line nevashandi vehutano vakadzidziswa munzvimbo yechipatara.

Chikwata chako chekurapa chichaisa chubhu diki mutsinga yako, kazhinji muruoko rwako kana ruoko. Vachabva zvishoma nezvishoma vachibaya mushonga zvakananga mumuviri wako kwemaminitsi akati wandei.

Nguva yekutora mishonga inoenderana nemamiriro ako chaiwo uye kuti muviri wako unopindura sei. Vanachiremba vako vachatarisa ropa rako, kurova kwemoyo, uye kushanda kwenhengo nguva dzose kuti vaone nguva yakakodzera yekupa mishonga.

Haufanire kunetseka nezvekudyidzana kwechikafu kana zvinwiwa sezvo uchizogamuchirawo rubatsiro rwekurapa muchipatara. Chikwata chako chekurapa chichabata zvese zvekupa mishonga.

Ndingatora Terlipressin Kwenguva Yakareba Sei?

Kureba kwekurapa kwe terlipressin kunosiyana zvakanyanya zvichienderana nemamiriro ako uye nekukurumidza kwemuviri wako unopindura. Vamwe vanhu vanoda mishonga iyi kwemazuva mashoma chete, asi vamwe vangada kurapwa kwemavhiki akati wandei.

Kune hepatorenal syndrome, kurapwa kunowanzoenderera kusvika basa reitsvo rako ravandudzwa kana kusvika vanachiremba vaona kuti mushonga haubatsiri. Iyi nzira inogona kutora chero kubva kumazuva mashoma kusvika kumavhiki akati wandei.

Muzviitiko zve septic shock, iwe unowanzo gamuchira terlipressin kusvika ropa rako ragadzikana uye muviri wako unogona kuchengetedza kutenderera kwakakwana wega. Chikwata chako chekurapa chichaderedza zvishoma nezvishoma mushonga panzvimbo yekumisa kamwe kamwe.

Vanachiremba vako vachagara vachiongorora kana mushonga uchibatsira uye vachigadzirisa chirongwa chekurapa zvinoenderana. Vachatarisawo chero zviratidzo zvekuti ungave uri kusangana nemhedzisiro inodarika mabhenefiti.

Ndezvipi Zvakaipa zveTerlipressin?

Terlipressin inogona kukonzera mhedzisiro yakati wandei nekuda kwemhedzisiro yayo ine simba pamidzi yeropa nhengo dzako. Chikwata chako chekurapa chichakutarisa zvakanyanya kuti uone izvi zvinopindura panguva yekurapa kwako.

Mhedzisiro yakajairika yaungasangana nayo inosanganisira shanduko mukurova kwemoyo wako, kuwedzera kweropa, uye kuderedzwa kweropa kumunwe wako netsoka. Ungaona maoko ako netsoka achitonhora kana achiita seakapfava.

Heano mhedzisiro yakajairika iyo zvikwata zvekurapa zvinoona:

• Kurova kwemoyo kusina kugadzikana kana shanduko mune rhythm yemoyo
• Kuvhiringidzika kweropa kwakanyanya
• Kuderera kweropa kumawoko netsoka
• Kurwadziwa mudumbu kana mumatumbu
• Kusvotwa kana kurutsa
• Kurwadziwa nemusoro
• Kutukirwa

Izvi zvinowanzoitika zvinowanzoita zviri nani sezvo muviri wako uchigadzirisa mushonga kana vanachiremba vachigadzirisa dose.

Vamwe vanhu vanowana mhedzisiro yakakomba inoda kutariswa kwekurapa nekukurumidza. Izvi zvisingawanzoitiki asi zvinonetsa zvinogona kukanganisa moyo wako, kutenderera, kana zvimwe zvikamu zvakakosha.

Mhedzisiro yakakomba inoda kutariswa nekukurumidza inosanganisira:

• Kurwadziwa kwakanyanya muchipfuva kana zviratidzo zvekurwisa kwemoyo
• Kurwadziwa kwemusoro kwakanyanya kana zviratidzo zve stroke
• Zviratidzo zvekuderera kweropa kumitezo (kusagadzikana, kurwadziwa mudumbu kwakanyanya)
• Maitiro akakomba ekugadzirisa muviri ane matambudziko ekufema kana kuzvimba
• Zviratidzo zverufu rwetishu mumunwe kana zvigunwe

Chikwata chako chekurapa chakadzidziswa kuziva izvi zviitiko zvakakomba nekukurumidza uye chichagadzirisa kurapwa kwako nekukurumidza kana zvikaonekwa.

Ndiani Asingafaniri Kutora Terlipressin?

Vamwe vanhu havagone kugamuchira terlipressin zvakachengeteka nekuda kwekuwedzera njodzi yematambudziko akakomba. Chikwata chako chekurapa chichanyatsoongorora nhoroondo yako yekurapa usati watanga kurapwa uku.

Haufanire kugamuchira terlipressin kana uine chirwere chemoyo chakakomba, kunyanya mamiriro anokanganisa ropa remoyo wako. Mushonga unogona kuderedza kuyerera kweropa kumhasuru dzemoyo wako, izvo zvinogona kuva njodzi.

Vanhu vane matambudziko ekutenderera ropa vanotarisanawo nenjodzi yepamusoro. Kana uine zvipingamupinyi zvakakomba mumidziyo yako yeropa kana nhoroondo yekuderera kweropa kumitezo yakakosha, terlipressin ingasava yakachengeteka kwauri.

Heano mamiriro anowanzo kudzivirira kushandiswa kwe terlipressin:

• Kutambudzika kwakanyanya kwetsinga dzemoyo kana kurwisa kwemoyo kwemazuva ano
• Matambudziko akakomba ekurira kwemoyo
• Kutambudzika kwakanyanya kwetsinga dzeropa dzemumakumbo
• Kuziva allergy ku terlipressin kana mishonga yakafanana
• Mhando dzakasiyana dzeropa rakakwira zvakanyanya
• Kuvhiyiwa kukuru kwemazuva ano patsinga dzeropa

Vanachiremba vako vachayerera njodzi nemabhenefiti zvakanyatsonaka, kunyanya kana uine chero mamiriro ezvinhu aya asi wakatarisana nekukurumidzira kunotyisa upenyu.

Mazita eBrand eTerlipressin

Terlipressin inowanikwa pasi pemazita akati wandei ebrand zvichienderana nenzvimbo yako uye maitiro chaiwo. MuUnited States, unogona kusangana nayo seTerlivaz, iro zita rebrand rakatenderwa neFDA.

Mune dzimwe nyika, terlipressin inoenda nemazita akasiyana ebrand akadai seGlypressin, Haemopressin, kana Variquel. Mushonga unoshanda ndewakafanana zvisinei nezita rebrand.

Chikwata chako chekurapa chichashandisa chero maitiro anowanikwa muchipatara chako. Ese akatenderwa mhando dze terlipressin anopfuura nemuyedzo wakafanana wakaoma wekuchengeteka uye kushanda.

Zvimwe Zvinhu zveTerlipressin

Mishonga yakati wandei inogona kurapa mamiriro akafanana ne terlipressin, kunyangwe vanachiremba vachisarudza zvichienderana nemamiriro ako chaiwo uye zvaunoda zvekurapa. Izvi zvimwe zvinoshanda kuburikidza nemaitiro akasiyana asi zvinovavarira kuwana mhedzisiro yakafanana.

Norepinephrine ndiyo inogona kunge iri imwe vasopressor inoshandiswa zvakanyanya ye septic shock. Inoshanda nekukurumidza kupfuura terlipressin asi inoda kuenderera mberi infusion, zvinoreva kuti iwe unozoda constant IV drip panzvimbo yemadosi anopindirana.

Ye hepatorenal syndrome kunyanya, vanachiremba vanogona kushandisa albumin infusions yakasanganiswa nemimwe mishonga yakaita se midodrine uye octreotide. Iyi nzira yekusanganisa dzimwe nguva inogona kuwana mhedzisiro yakafanana ne terlipressin.

Dzimwe nzira dzekushandisa vasopressor dzinosanganisira vasopressin, epinephrine, uye dopamine. Imwe neimwe ine simba rayo rakasiyana uye inosarudzwa zvichienderana nemamiriro ako chaiwo uye kuti muviri wako unopindura sei kurapwa.

Ko Terlipressin Ari Nani Pane Norepinephrine?

Kana terlipressin iri nani pane norepinephrine zvinoenderana nemamiriro ako chaiwo uye kupindura kwemunhu kumishonga. Mishonga yese miviri inoshanda vasopressors, asi inoshanda zvakasiyana uye ine zvakanakira zvakasiyana.

Terlipressin inogara kwenguva refu mumuviri wako, saka vanachiremba vanogona kuipa kazhinji kushoma pane norepinephrine. Izvi zvinogona kuve mukana mune mamwe mamiriro, kunyanya kana kuchengetedza ropa rinogara richinetsa.

Norepinephrine inoshanda nekukurumidza uye inopa vanachiremba kutonga kwakanyanya pamusoro peropa rako. Vanogona kugadzirisa muyero miniti neminiti, izvo zvinogona kukosha panguva yekukurumidza kuchinja kwekurapa.

Kune hepatorenal syndrome kunyanya, terlipressin yakaratidza kushanda zvakanyanya uye inowanzo sarudzwa. Kune septic shock, norepinephrine inowanzoita yekutanga-mutsara kurapwa, ne terlipressin inoshandiswa kana norepinephrine isina kukwana.

Chikwata chako chekurapa chichasarudza sarudzo yakanakisa zvichienderana nemamiriro ako chaiwo, mamwe mishonga yaunogamuchira, uye nekukurumidza kwaunoda kutsigirwa kweropa.

Mibvunzo Inowanzo Bvunzwa Nezve Terlipressin

Ko Terlipressin Akachengeteka Kune Vanhu vane Chirwere Chemoyo?

Terlipressin inoda kungwarira zvakanyanya muvanhu vane chirwere chemoyo uye inogona kusachengeteka kune avo vane chirwere chakakomba checoronary artery. Mushonga unogona kuderedza kuyerera kweropa kumhasuru dzemoyo wako, izvo zvinogona kuwedzera matambudziko emoyo.

Kana uine chirwere chemoyo chinyoro kusvika pakati nepakati, vanachiremba vako vachayerera njodzi dzinotyisa dzeupenyu dzemamiriro ako azvino pamusoro penjodzi dzemoyo dze terlipressin. Vachatarisa basa remoyo wako zvakanyanya panguva yekurapa.

Vanhu vane chirwere chemoyo chakakomba, kurwisa kwemoyo kuchangobva kuitika, kana kurwadziwa muchipfuva kusina kugadzikana kazhinji havagone kugamuchira terlipressin zvakachengeteka. Chikwata chako chekurapa chichafunga nezve mamwe marapirwo anopa njodzi shoma kumoyo wako.

Ndingaita Sei Kana Ndikagamuchira Terlipressin Yakawandisa Netsaona?

Haugone netsaona kugamuchira terlipressin yakawandisa nekuti nyanzvi dzekurapa dzakadzidziswa dzinodzora zvese zvekuyera mumamiriro ezvinhu echipatara. Zvisinei, kana iwe ukawana zviratidzo zvekurapa kwakawandisa, chikwata chako chekurapa chichapindura nekukasira.

Zviratidzo zve terlipressin yakawandisa zvinosanganisira kuwedzera kwakanyanya kweropa, kurwadziwa muchipfuva, kurwadziwa kwemusoro kwakanyanya, kana zviratidzo zvekuwedzera kweropa kumuviri wako. Chikwata chako chekurapa chinotarisa zviratidzo izvi nguva dzose.

Kana overdose ikaitika, vanachiremba vachamisa mushonga nekukasira uye vopa rutsigiro. Vanogona kukupa mishonga yekurwisa mhedzisiro kana kubatsira kubata chero matambudziko anomuka.

Ndingaita Sei Kana Ndikakanganwa Dose yeTerlipressin?

Haufanire kunetseka nezvekukanganwa madosi nekuti chikwata chako chekurapa chinotungamira zvese zvekupa terlipressin. Vanotevera chirongwa chakatarwa zvichienderana nemamiriro ako uye kupindura kurapwa.

Kana chikwata chako chekurapa chikanonoka dose nechikonzero chipi zvacho, vachagadzirisa chirongwa chako chekurapa zvinoenderana. Vanogona kupa dose yakarasika kana zvakachengeteka kuita kudaro, kana vanogona kuchinja nguva yemadosi emunguva yemberi.

Vanachiremba vako vanoramba vachitarisa mamiriro ako uye vachave nechokwadi chekuti unogamuchira huwandu hwemushonga panguva dzakakodzera. Vachaita chero kugadzirisa kwakakodzera kuti vakuchengetedze uye vawedzere kurapwa kwako.

Ndingamira Rini Kutora Terlipressin?

Chikwata chako chekurapa chichasarudza kana kumisa terlipressin zvichienderana nekupindura kwako kurapwa uye kuvandudzwa mumamiriro ako ezvinhu. Sarudzo iyi inoda kutonga kwekurapa kwakanyatsojeka uye haigone kuitwa nevarwere kana nhengo dzemhuri.

Kazhinji, vanachiremba vanomisa terlipressin kana ropa rako richidzika, basa remapapu ako richivandudzika, kana mushonga wacho usingachabatsiri mamiriro ako. Vachaderedza zvishoma nezvishoma mushonga wacho pane kumisa kamwechete.

Maitiro ekumisa mushonga uyu akasiyana-siyana kubva kumunhu nemunhu. Vamwe vanhu vanogona kumisa terlipressin mumazuva mashoma, asi vamwe vanoda kuderedzwa zvishoma nezvishoma kwemavhiki. Chikwata chako chekurapa chichakutarisa zvakanyanya panguva iyi yekuchinja.

Ko Terlipressin Inogona Kukonzera Matambudziko Enguva Refu Here?

Matambudziko mazhinji e terlipressin anopera kana kurapwa kwapera, asi vamwe vanhu vanogona kusangana nemigumisiro inogara kwenguva refu zvichienderana neutano hwavo hwese uye nguva yekurapwa. Chikwata chako chekurapa chichakutarisa chero matambudziko ari kuenderera mberi.

Mhedzisiro inonyanya kukosha yenguva refu ndeyekuderera kweropa kumunwe kana zvigunwe, izvo mune zviitiko zvisingawanzoitiki zvinogona kukonzera kukuvadzwa kwematishu. Chikwata chako chekurapa chinonyatso tarisa zviratidzo zvekutanga zvematambudziko ekutenderera kweropa.

Vanhu vazhinji vanopora zvizere kubva mukurapwa kwe terlipressin vasina migumisiro inogara. Zvisinei, vanachiremba vako vacharamba vachitarisa moyo wako, mapapu, uye basa rekutenderera ropa kunyange mushure mekunge kurapwa kwapera kuti vave nechokwadi chekupora kwakakwana.