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Chii chinonzi Upadacitinib: Zvazvinoshandiswa, Madosi, Migumisiro Yakaipa nezvimwe

Created at:1/13/2025

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Upadacitinib mushonga unotarisa uyo unobatsira kudzikamisa immune system yako kana yakanyanya kushanda. Mushonga uyu unopiwa nachiremba unobva kuboka rinonzi JAK inhibitors, iro rinoshanda nekudzivisa mapurotini akati wandei anokonzera kuzvimba mumuviri wako.

Funga nezvazvo sechishandiso chakarurama chinobatsira kudzikisa ruzha pamhinduro yekuzvimba ye immune system yako. Chiremba wako angakupa upadacitinib kana muviri wako wekudzivirira wakatanga kurwisa matishu ane hutano, zvichikonzera kuzvimba kunorwadza uye kukuvara.

Chii chinonzi Upadacitinib chinoshandiswa?

Upadacitinib inorapa mamiriro akati wandei e autoimmune uko immune system yako inokanganisa muviri wako. Mushonga uyu unonyanya kupiwa rheumatoid arthritis, psoriatic arthritis, uye mamwe mamiriro eganda senge atopic dermatitis.

Chiremba wako angakurudzira mushonga uyu kana dzimwe nzira dzekurapa dzisina kupa rubatsiro rwakakwana kubva kuzviratidzo zvako. Zvinobatsira zvikuru kune vanhu vane fomu repakati nepakati yezvinhu izvi vanoda kupindira kwakasimba kupfuura izvo zvinorapwa zvekumusoro kana mishonga yakajairika inogona kupa.

Mushonga uyu unoshandiswawo ankylosing spondylitis, rudzi rwe arthritis runonyanya kukanganisa musana wako. Mune zvimwe zviitiko, vanachiremba vanozvipa ulcerative colitis, mamiriro ekuzvimba mudumbu anokonzera kuzvimba kunoenderera mberi munzira yako yekugaya.

Upadacitinib inoshanda sei?

Upadacitinib inodzivisa mapurotini anonzi JAK enzymes anotumira zviratidzo zvekuzvimba mumuviri wako wese. Kana ma enzymes aya akanyanya kushanda, anokonzera kuzvimba kunorwadza uye kukuvara kwematishu kwaunoona nemamiriro e autoimmune.

Nekukanganisa nzira idzi dzekuzvimba, mushonga unobatsira kuderedza kuzvimba, kurwadziwa, uye kufambira mberi kwekukuvara kwemajoini. Inoonekwa semushonga wakasimba zvishoma unopa chiito chakatarisa kupfuura zvinodhaka zvekare zvinodzvinyirira immune.

Mushonga unoshanda pamwero wecellular kudzivirira maseru ako ekudzivirira kubva pakugadzira huwandu hwakanyanya hwezvinhu zvinopisa. Iyi nzira yakatarwa zvinoreva kuti inogona kushanda uku ichikonzera mashoma mativi emuviri pane vanodzvinyirira immune system.

Ndingatora sei Upadacitinib?

Tora upadacitinib sezvakanyorwa nachiremba wako, kazhinji kamwe pazuva uine kana pasina chikafu. Medza piritsi rose nemvura uye usapwanye, kupatsanura, kana kuitsenga, sezvo izvi zvinogona kukanganisa nzira iyo mushonga unosunungurwa mumuviri wako.

Unogona kuitora chero nguva yezuva, asi edza kuitora panguva imwechete zuva rega rega kuti uchengetedze mazinga akagadzikana muhurongwa hwako. Kuitora nechikafu kunogona kubatsira kuderedza dumbu kana uine kusagadzikana kwekudya.

Chiremba wako achakutanga pane chiyero chakati wandei zvichienderana nemamiriro ako uye maitiro ako kumushonga. Vanogona kugadzirisa chiyero chako nekufamba kwenguva, saka zvakakosha kutevera gwara ravo uye usachinje huwandu hwega.

Ndingatora Upadacitinib kwenguva yakareba sei?

Kureba kwekurapa kweupadacitinib kunosiyana zvichienderana nemamiriro ako chaiwo uye kuti unopindura sei kumushonga. Vanhu vazhinji vane mamiriro e-autoimmune echronic vanoiita kwenguva refu kuti vachengetedze kutonga kwezviratidzo zvavo.

Chiremba wako achagara achitarisa kufambira mberi kwako uye anogona kugadzirisa chirongwa chako chekurapa zvichienderana nekuti unonzwa sei uye mibairo yako yelab. Vamwe vanhu vanoona kuvandudzwa mukati memavhiki mashoma, nepo vamwe vachigona kuda mwedzi yakati wandei kuti vawane mabhenefiti akazara.

Usambomira kutora upadacitinib kamwechete usati wataura nachiremba wako kutanga. Vanogona kuda kuderedza zvishoma nezvishoma chiyero chako kana kukuchinjira kune mumwe mushonga kudzivirira zviratidzo zvako kubva pakudzoka.

Ndezvipi Zvakaipa zveUpadacitinib?

Sezvinongoita mishonga yese inokanganisa immune system yako, upadacitinib inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anoiona. Mhedzisiro zhinji inogoneka, uye chiremba wako achakutarisa zvakanyanya kuti abate chero matambudziko ekutanga.

Heano mhedzisiro yakajairika yaungasangana nayo paunenge uchitora mushonga uyu:

  • Zvirwere zvepamusoro zvekufema zvakaita sema colds kana sinus infections
  • Nausea kana kusagadzikana mudumbu
  • Kuwedzera njodzi yezvirwere nekuda kwe immune system suppression
  • Kuwedzera kwechiropa enzymes inoratidzwa mumiedzo yeropa
  • Kutemwa nemusoro
  • Acne kana ganda reactions
  • Kuwedzera cholesterol mazinga

Zvizhinji zvezvinhu izvi zvakapfava uye zvinowanzoita nani muviri wako paunojaira mushonga. Chiremba wako achaita bvunzo dzeropa nguva dzose kuti atarise chiropa chako uye hutano hwese.

Kune zvakare mamwe akakomba asi asingawanzoitika mhedzisiro inoda kutariswa kwekurapa nekukurumidza. Kunyangwe izvi zvisingaitike kazhinji, zvakakosha kuziva nezvazvo:

  • Zvirwere zvakakomba zvinogona kuisa hupenyu panjodzi
  • Blood clots mumakumbo, mapapu, kana dzimwe nhengo dzemuviri
  • Kuchinja kukuru mukuverenga maseru eropa
  • Matambudziko akakomba echiropa
  • Kuwedzera njodzi yemamwe marudzi ekenza
  • Zviitiko zve cardiovascular zvakaita sechirwere chemoyo kana sitiroko

Kana ukaona fivha, kukosora kunoramba kuripo, kuneta kusinganzwisisike, kana chero zviratidzo zvechirwere, taura nachiremba wako nekukurumidza. Matambudziko aya asingawanzoitika ndicho chikonzero nei kuongorora nguva dzose kwakakosha.

Ndiani Asingafaniri Kutora Upadacitinib?

Upadacitinib haina kukodzera munhu wese, uye chiremba wako achanyatsoongorora kana yakakukodzera. Vanhu vane zvirwere zvakakomba zviripo havafaniri kutanga mushonga uyu kusvikira chirwere chacho chabatwa zvizere.

Unofanira kudzivisa upadacitinib kana uchiziva kuti une allergy kumushonga uyu kana chero zvimwe zvawo. Vanhu vane matambudziko makuru echiropa kana avo vakambova nemhando dzakasiyana dzekenza vanogonawo kuda kudzivisa kurapwa uku.

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Chiremba wako achava akanyatso chenjerera kana uine nhoroondo yegwamba reropa, matambudziko emoyo, kana sitiroko. Vanhu vane makore anopfuura 65, avo vanopfungaira, kana vanhu vane njodzi yezvirwere zve cardiovascular vanoda kufunga zvakakosha vasati vatanga kurapwa.

Kana uri nepamuviri, uchironga kuva nepamuviri, kana kuyamwisa, kurukura mamiriro aya nachiremba wako. Mhedzisiro ye upadacitinib panguva yekuzvitakura nekuyamwisa hazvizivikanwe zvakakwana, saka dzimwe nzira dzekurapa dzinogona kuva dzakachengeteka.

Mazita eBrand eUpadacitinib

Upadacitinib inowanikwa pasi pezita rebrand Rinvoq munyika zhinji. Iri ndiro zita rekutanga rebrand rauchaona pabhodhoro rako remishonga uye kurongwa kwemishonga.

Mishonga iyi inogadzirwa neAbbVie uye inouya mumahwendefa ekuburitswa kwenguva refu emasimba akasiyana. Pharmacy yako inowanzo kupa mhando yeRinvoq kunze kwekunge chiremba wako achinyora zvakananga vhezheni yegeneric, iyo ingasawanikwe zvakanyanya.

Zvimwe Zvinhu Zviri Kufanana neUpadacitinib

Mishonga yakati wandei inoshanda zvakafanana ne upadacitinib kana kurapwa uku kusina kukodzera iwe. Zvimwe zvinodzivirira JAK zvinosanganisira tofacitinib (Xeljanz) uye baricitinib (Olumiant), iyo inovhara nzira imwechete yekuzvimba asi inogona kuva nemhedzisiro yakasiyana.

Mishonga yebiologic senge adalimumab (Humira), etanercept (Enbrel), kana infliximab (Remicade) inopa nzira dzakasiyana dzekurapa mamiriro eautoimmune. Izvi zvinoshanda nekunangana nemapuroteni chaiwo anobatanidzwa mukuzvimba pane kuvhara ma enzyme eJAK.

Mishonga yechinyakare yekuchinja zvirwere zve rheumatic (DMARDs) senge methotrexate kana sulfasalazine inogona kuve sarudzo kune vamwe vanhu. Chiremba wako achatarisa mamiriro ako chaiwo, nhoroondo yako yezvokurapa, uye zvinangwa zvekurapa paanokurudzira dzimwe nzira.

Ko Upadacitinib Zviri Nani Kupfuura Adalimumab?

Vese upadacitinib uye adalimumab ndiyo kurapwa kunoshanda kune autoimmune mamiriro, asi anoshanda kuburikidza nemaitiro akasiyana. Upadacitinib inotorwa semupiritsi wezuva nezuva, nepo adalimumab ichida majekiseni enguva dzose pasi peganda.

Vamwe vanhu vanosarudza nyore nyore kutora piritsi rezuva nezuva pane kuzvipa majekiseni. Zvisinei, adalimumab yakashandiswa kwemakore mazhinji uye ine yakagadzwa zvakanaka kuchengeteka kwemaitiro ayo vanachiremba vanojairana nawo.

Sarudzo pakati pemishonga iyi inoenderana nemamiriro ako chaiwo, maitiro ako kumamwe marapirwo, uye zvaunofarira. Chiremba wako achatarisa zvinhu zvakaita se njodzi yako yekutapukirwa, hutano hwemoyo, uye mararamiro paanoita sarudzo iyi.

Mibvunzo Inowanzo bvunzwa Nezve Upadacitinib

Mubvunzo 1. Ko Upadacitinib Yakachengeteka Kune Vanhu vane Chirwere cheShuga?

Upadacitinib inogona kushandiswa zvakachengeteka muvanhu vane chirwere cheshuga, asi chiremba wako achakutarisa zvakanyanya. Mushonga hauna zvakananga kukanganisa mazinga eshuga yeropa, asi mamwe mativi emhedzisiro senge kuwedzera njodzi yekutapukirwa inogona kunge ichinetesa kune vanhu vane chirwere cheshuga.

Chiremba wako achada kuona kuti chirwere chako cheshuga chiri kudzora zvakanaka usati watanga upadacitinib. Vanogona zvakare kubatana nechikwata chako chekuchengetedza chirwere cheshuga kuti vagadzirise hurongwa hwekuongorora uye tarisa chero matambudziko.

Mubvunzo 2. Ndoitei Kana Ndikangoerekana Ndatora Upadacitinib Yakawandisa?

Kana iwe ukangoerekana watora upadacitinib yakawanda kupfuura yakarairwa, taura nachiremba wako kana nzvimbo yekudzora chepfu nekukasira. Usamirire kuti uone kana uchinzwa kurwara, sezvo kuwana zano nekukurumidza kwakakosha kuchengeteka kwako.

Chengetai bhodhoro remushonga nemi kana muchifona kuti muvazivise zvakananga zvamatorwa uye rini. Vakawanda vanopa hutano vanoda kuongorora zvakanyanya zvinogona kuitika zvekupfuurisa mushonga nekukurumidza pane kumirira zviratidzo kuti zviitike.

Q3. Ndoitei Kana Ndakakanganwa Kudya Mushonga weUpadacitinib?

Kana makanganwa kudya mushonga weupadacitinib, udyei nekukurumidza pamunorangarira pazuva rimwe chetero. Zvisinei, kana yava nguva yekutora mushonga unotevera, regai kudya mushonga wamakanganwa uye rambai muchidya mushonga wenyu nguva dzose.

Musambofa makatora mishonga miviri panguva imwe chete kuti muzadze mushonga wamakanganwa, sezvo izvi zvinogona kuwedzera njodzi yezvinhu zvisina kunaka. Kana muchikanganwa kudya mishonga nguva zhinji, fungai kuisa alarm yezuva nezuva kana kushandisa chirongwa chemishonga kuti zvikubatsirei kurangarira.

Q4. Ndingamira Rini Kudya Upadacitinib?

Mungamira kudya upadacitinib chete kana chiremba wenyu akakurairai kudaro. Kumira kamwe kamwe kunogona kukonzera kuti zviratidzo zvenyu zvidzoke, dzimwe nguva zvakanyanya kupfuura zvisati zvaitika kuti mutange kurapwa.

Chiremba wenyu achagara achiongorora kana muchiri kuda mushonga zvichienderana nezviratidzo zvenyu, mibairo yelabhu, uye hutano hwose. Vanogona kuderedza zvishoma nezvishoma mushonga wenyu kana kukuchinjirai kumushonga wakasiyana kana kuchinja kuchidiwa.

Q5. Ndingabaiwa Majekiseni Here Ndichidya Upadacitinib?

Munofanira kudzivisa majekiseni mhenyu muchidya upadacitinib, asi majekiseni akawanda enguva dzose akachengeteka uye anowanzo kurairwa. Chiremba wenyu achada kuti muve muchidya majekiseni akaita semajekiseni eflu nemajekiseni e pneumonia musati matanga kurapwa.

Taura nachiremba wenyu musati mabaiwa jekiseni ripi zvaro kuti muve nechokwadi chekuti rakachengeteka nemushonga wenyu wazvino. Vanogona kuraira nguva yemamwe majekiseni akapoteredza chirongwa chenyu chemushonga kuti muve nechokwadi chekudzivirirwa kwakanaka.

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