Chii chinonzi Velaglucerase Alfa: Zvazvinoshandiswa, Mushonga, Mativi eMuviri uye Zvimwe

Velaglucerase alfa mushonga unotsiva ma enzymes unopiwa kuburikidza ne IV kurapa chirwere cheGaucher mhando 1. Mushonga uyu unoshanda nekutsiva enzyme isipo kana isina kukwana iyo muviri wako unoda kuparadza mafuta akati wandei, zvichibatsira kuderedza kuwanda kunokonzera zviratidzo zvakaita semitezo yakakura uye matambudziko emapfupa.

Chii chinonzi Velaglucerase Alfa?

Velaglucerase alfa ndiyo vhezheni yakagadzirwa nemunhu ye enzyme glucocerebrosidase iyo muviri wako unogadzira zvakasikwa. Mune vanhu vane chirwere cheGaucher, enzyme iyi haishande zvakanaka kana kuti haina zvachose, zvichikonzera kuti zvinhu zvine mafuta zviwande mumasero mumuviri wese.

Mushonga uyu unogadzirwa uchishandisa mitsara yemasero evanhu murabhoritari, zvichiita kuti zvifanane ne enzyme iyo muviri wako unowanzoita. Kufanana uku kunobatsira kuderedza njodzi yekuti immune system yako irambe kurapwa. Iwe uchagamuchira mushonga uyu se infusion zvakananga muropa rako panzvimbo yekurapa.

Velaglucerase Alfa Inoshandiswa Kuti Chii?

Velaglucerase alfa inorapa chirwere cheGaucher mhando 1 muvanhu vakuru nevana vane makore anopfuura 4. Chirwere cheGaucher imamiriro ezvinhu emagenetic apo muviri wako haugone kuparadza zvakanaka chinhu chine mafuta chinonzi glucocerebroside.

Kuwedzera uku kunogona kukonzera kuti spleen yako nechiropa zvive zvakakura, kutungamira kune huwandu hweropa rakaderera, uye kugadzira matambudziko emapfupa akaita sekurwadziwa uye mabhureki. Mushonga uyu unobatsira muviri wako kugadzirisa zvinhu izvi zvine mafuta zvinobudirira, izvo zvinogona kuvandudza zviratidzo izvi nekufamba kwenguva.

Chiremba wako angangofungawo nezvekurapa uku kana uine matambudziko akati wandei kubva kuchirwere cheGaucher, senge anemia yakakomba, chirwere chakakosha chemapfupa, kana kana spleen yako yakakura iri kukonzera matambudziko akakomba. Zvisinei, mushonga uyu ndewe chirwere cheGaucher mhando 1 uye hauzobatsiri nezviratidzo zve neurological zvinoonekwa mumhando 2 ne 3.

Velaglucerase Alfa Inoshanda Sei?

Velaglucerase alfa inoshanda nekupa muviri wako enzyme yaunoshaya kuti iparadze zvinhu zvine mafuta zvakanaka. Funga nezvazvo sekupa kiyi inovhura gonhi rekugadzirisa mafuta anga achiunganidzwa mumasero ako.

Iri rinotariswa semushonga wakasimba, wakanangana nekuti unotarisana zvakananga nemudzi wechirwere cheGaucher panzvimbo yekungorapa zviratidzo. Kana yaiswa muropa rako, enzyme inofamba ichienda kumasero mumuviri wako wese, kunyanya muchiropa chako, spleen, uye muviri wemuzongoza uko kuunganidzwa kwemafuta kunowanzoitika.

Maitiro acho haasi echimbichimbi - zvinogona kutora mwedzi yakati wandei kuti uone kuvandudzwa kukuru muzviratidzo zvako. Muviri wako unoda nguva yekuchenesa zvishoma nezvishoma zvinhu zvakaunganidzwa zvine mafuta uye kuti nhengo dzako dzidzokere kuhukuru hwakajairika uye kushanda.

Ndingatora sei Velaglucerase Alfa?

Iwe uchagamuchira velaglucerase alfa seIV infusion kuchipatara kana nzvimbo yekuiswa, kwete kumba. Kurapa kunowanzo kutora maminitsi makumi matanhatu, uye uchada kuuya mumasvondo maviri ega ega kuti uwane mushonga wako wakarongeka.

Usati waiswa, timu yako yehutano inogona kukupa mishonga yekudzivirira maitiro ekuita allergic, senge antihistamines kana acetaminophen. Hauzodi kutsanya zvisati zvaitika, uye unogona kudya zvakajairika usati watora mushonga wako uye mushure mawo. Zvisinei, zvakanaka kuti ugare uine mvura yakawanda nekunwa mvura yakawanda.

Panguva yekuiswa, iwe uchaongororwa chero maitiro. Vamwe vanhu vanonzwa vakasununguka kuunza bhuku, piritsi, kana dzimwe mabhuku akanyarara sezvo uchagara kweawa imwe. Chikwata chako chehutano chichaongorora zviratidzo zvako zvakakosha nguva dzose uye chichatarisa chero zviratidzo zvekuita allergic.

Ndingatora Velaglucerase Alfa kwenguva yakareba sei?

Velaglucerase alfa inowanzoita kurapwa kwehupenyu hwese kwechirwere cheGaucher. Sezvo iyi iri mamiriro emagenetic, muviri wako unogara uine dambudziko rekugadzira enzyme yaunoda, saka kurapwa kwekuenderera mberi kunowanzoita zvakafanira.

Chiremba wako achatarisa kufambira mberi kwako kuburikidza nemiedzo yeropa yenguva dzose uye zvidzidzo zvekuona kuti uone kuti kurapwa kuri kushanda sei. Vamwe vanhu vanogona kuona kuvandudzwa mumavara eropa mukati memwedzi mishoma, nepo shanduko muhukuru hwemuviri uye hutano hwemapfupa zvinogona kutora mwedzi mitanhatu kusvika kumakore akati wandei.

Sarudzo yekuramba kurapwa inoenderana nekuti uri kupindura sei uye kana uri kusangana nechero mativi akakosha. Chikwata chako chehutano chichashanda newe kuti uwane chiyero chakakodzera pakati pekutarisira chirwere chako cheGaucher uye kuchengetedza hupenyu hwako.

Ndezvipi Zvipingamupinyi zveVelaglucerase Alfa?

Vanhu vazhinji vanotsungirira velaglucerase alfa zvakanaka, asi semushonga chero upi zvake, unogona kukonzera mativi. Zvinhu zvakajairika zvinowanzoita zvinyoro uye zvinoitika panguva kana nguva pfupi mushure mekuiswa kwako.

Heano mativi akajairika aunogona kusangana nawo:

• Kutemwa nemusoro uye kuneta
• Nausea kana dumbu rinogumbuka
• Kurwadziwa kwemajoini kana kurwadziwa kwemhasuru
• Fivha yakapfava kana kutonhora
• Kurwadziwa, kuzvimba, kana kutsvuka panzvimbo yeIV
• Dizziness kana kunzwa lightheaded

Zviratidzo izvi zvinowanzoita zviri nani sezvo muviri wako uchijaira kurapwa. Chikwata chako chehutano chinogona kubatsira kutarisira mativi aya nemishonga kana nekugadzirisa nekukurumidza kwaunogamuchira infusion.

Zvimwe zviitiko zvakakomba hazviwanzoitiki asi zvinogona kusanganisira maitiro akakomba ekuita allergic. Zviratidzo zvekutarisa zvinosanganisira kuoma kufema, kusimba kwemupfu, rash yakakomba, kana kuzvimba kwechiso chako, miromo, kana huro. Kana iwe ukasangana nechero zviratidzo izvi, udza chikwata chako chehutano nekukurumidza.

Vamwe vanhu vanogona kukudziridza masoja ekurwisa mushonga nekufamba kwenguva, izvo zvinogona kuita kuti zvisashande zvakanyanya. Chiremba wako achatarisa izvi kuburikidza nemiedzo yeropa uye achakurukura dzimwe nzira dzekurapa kana zvichidikanwa.

Ndiani Asingafaniri Kutora Velaglucerase Alfa?

Velaglucerase alfa haikodzere munhu wese ane chirwere cheGaucher. Haufaniri kugamuchira mushonga uyu kana wakambove ne allergic reaction yakakomba kwauri munguva yakapfuura kana uine allergic kune chero zvinhu zvawo.

Chiremba wako achava akanyatso chenjerera kana uine nhoroondo ye allergies dzakakomba kana kana wakambove ne reactions kune mamwe marapirwo ekutsiva enzyme. Vanhu vane mamwe mamiriro emoyo vangada kuongororwa zvakakosha panguva yekuiswa sezvo allergic reactions inogona kukanganisa kumhanya kwemoyo wako uye kudzvanywa kweropa.

Mushonga uyu unobvumirwa chete chirwere cheGaucher mhando 1, saka hauzobatsiri kana uine mhando 2 kana 3, iyo inokanganisa tsinga dzemuviri. Vana vari pasi pemakore mana havana kudzidzwa zvakakwana kuti vaone kana kurapwa uku kwakachengeteka uye kuchibatsira kwavari.

Kana uri nepamuviri kana kuyamwisa, kurukura njodzi nemabhenefiti nachiremba wako. Kunyange zvazvo paine data shoma pakushandiswa panguva yekuzvitakura, mabhenefiti anogona kukunda njodzi kana uine chirwere chakakomba cheGaucher.

Zita reBrand reVelaglucerase Alfa

Velaglucerase alfa inotengeswa pasi pezita rebrand VPRIV. Iri ndiro zita rimwe chete rebrand rinowanikwa kune iyi chaiyo enzyme replacement therapy.

Paunenge uchironga misangano kana uchitaura nekambani yako yeinishuwarenzi, unogona kunzwa ichirehwa nezita rimwe chete. Zvese velaglucerase alfa uye VPRIV zvinoreva mushonga mumwe chete.

Velaglucerase Alfa Zvimwe Zvingasarudzwa

Kana velaglucerase alfa isingashande zvakanaka kwauri kana kukonzera matambudziko akawanda, pane dzimwe nzira dzekurapa chirwere cheGaucher mhando 1. Zvimwe zvikuru zvinosanganisira mamwe marapirwo ekutsiva enzyme uye mishonga yemuromo.

Imiglucerase (Cerezyme) imwe enzyme replacement therapy yakashandiswa kwenguva refu kupfuura velaglucerase alfa. Inopiwawo seIV infusion mazuva ese maviri uye inoshanda nenzira yakafanana. Vamwe vanhu vanogona kupindura zviri nani kune imwe enzyme therapy pane imwe.

Taliglucerase alfa (Elelyso) imhando itsva yekutsiva ma enzyme inopiwawo ne IV infusion. Inogadzirwa vachishandisa maseru emuti panzvimbo pemasero evanhu, izvo zvingave sarudzo kana ukaumba ma antibodies kune mamwe marapirwo e enzyme.

Kune vanhu vanosarudza kudzivisa IV infusions, kune mishonga yemuromo inonzi substrate reduction therapies. Izvi zvinosanganisira eliglustat (Cerdelga) uye miglustat (Zavesca), iyo inoshanda nekuderedza kugadzirwa kwezvinhu zvine mafuta zvinovaka muGaucher disease.

Ko Velaglucerase Alfa Ari Nani Kudarika Imiglucerase?

Vose velaglucerase alfa uye imiglucerase vanorapa zvakanaka Gaucher disease mhando 1, uye zvidzidzo zvinoratidza kuti vanoshanda zvakafanana. Sarudzo pakati pavo inowanzouya pasi kune zvinhu zvemunhu pane imwe iri pachena kupfuura.

Velaglucerase alfa inogona kuva nekubatsira kudiki maererano ne allergic reactions sezvo ichigadzirwa vachishandisa maseru evanhu, zvichiita kuti ive yakafanana ne enzyme yako yechisikigo. Izvi zvinogona kureva vanhu vashoma vanoita ma antibodies anogona kuderedza kushanda kwemushonga nekufamba kwenguva.

Zvisinei, imiglucerase yakashandiswa kwemakore mazhinji, saka vanachiremba vane ruzivo rwakawanda rwe nguva refu nayo. Vamwe vanhu vanogona kupindura zviri nani kumushonga mumwe pane mumwe, uye kuchinjana pakati pavo kunogoneka kana zvichidikanwa.

Chiremba wako achafunga nezvezvinhu zvakaita sezviratidzo zvako zvakananga, chero kupindura kwakamboitika kune enzyme therapies, uye kupindura kwako kwemunhu paanokurudzira kuti ndeupi murapi angashanda zvakanyanya kwauri.

Mibvunzo Inowanzo Bvunzwa Nezve Velaglucerase Alfa

Ko Velaglucerase Alfa Akachengeteka Kune Vanhu vane Chirwere Chemoyo?

Velaglucerase alfa inogona kushandiswa kune vanhu vane chirwere chemoyo, asi inoda kunyatso tariswa. Sezvo allergic reactions inogona kukanganisa kumhanya kwemoyo wako uye ropa, timu yako yehutano ichakutarisa zvakanyanya panguva ye infusions.

Kana uine matambudziko emoyo, chiremba wako angakurudzira mishonga yekutanga kuderedza njodzi yekuitika, kana kuti vangapa infusion zvishoma nezvishoma. Vanhu vazhinji vane matambudziko emoyo vanogamuchira kurapwa uku zvakachengeteka nekuchenjerera kwakakodzera.

Ndingaita Sei Kana Ndikagamuchira Zvakawandisa Velaglucerase Alfa Netsaona?

Sezvo velaglucerase alfa ichipiwa nenyanzvi dzezvehutano munzvimbo yekurapa, overdoses netsaona hazviwanzoitiki. Mushonga unoyereswa nekuchenjerera uye unotarisiswa panguva ye infusion yega yega.

Kana uine hanya nekugamuchira dose isiriyo, usazeza kubvunza timu yako yehutano nezvehuwandu hwauri kugamuchira. Vanogona kukuratidza kuti vanoverenga sei uye vanosimbisa dose yako zvichibva pauremu hwako uye mamiriro ako.

Ndingaita Sei Kana Ndikakanganwa Dose yeVelaglucerase Alfa?

Kana ukakanganwa infusion yako yakarongwa, taura nemupi wako wehutano nekukurumidza sezvinobvira kuti urongezve. Zvakakosha kuchengetedza kurapwa nguva dzose kuti urambe uine chirwere chako cheGaucher chichidzora.

Edza kudzokera pachirongwa nekukurumidza sezvinobvira, asi usanetseka kana uchida kukanganwa dose dzimwe nguva nekuda kwekurwara kana zvimwe zviitiko. Timu yako yehutano inogona kukubatsira kuronga pazororo, zvirongwa zvebasa, kana zvimwe zvisungo.

Ndingamira Rini Kutora Velaglucerase Alfa?

Haufanire kumbomira velaglucerase alfa usati wataurirana nachiremba wako kutanga. Sezvo chirwere cheGaucher chiri mamiriro emagenetic ehupenyu hwese, kumisa kurapwa zvingangokonzera zviratidzo zvako kudzoka nekufamba kwenguva.

Chiremba wako angatarisa zororo rekurapa mumamiriro ezvinhu asingawanzoitiki, sekunge panguva yemamwe maitiro ekurapa kana ukagadzira mhedzisiro yakakomba. Zvisinei, chero chisarudzo chekumisa kana kumisa kurapwa chinofanira kuitwa pamwe chete netimu yako yehutano uchinyatso tarisa mamiriro ako.

Ndingafamba Here Ndichitora Velaglucerase Alfa?

Hongu, unogona kufamba uchigamuchira kurapwa kwevelaglucerase alfa, asi zvinoda kuronga. Unozofanira kuronga infusions pazvipatara zvakabvumirwa pedyo nenzvimbo yaunoenda, kana unogona kufanira kuchinja mazuva ako ekufamba zvichienderana nechirongwa chako chekurapa.

Chikwata chako chehutano chinogona kukubatsira kuwana nzvimbo dzakakodzera dzekuisa dzimwe nzvimbo uye kuona kuti marekodhi ako ekurapa anotamiswa zvakakodzera. Vanhu vazhinji vanobudirira kutarisira kufamba vachiri pakurapa uku nekubatana kwakakodzera.