Created at:1/13/2025
Question on this topic? Get an instant answer from August.
Zafirlukast mushonga unopiwa nachiremba unobatsira kudzivirira kurwiswa kweasthma nekudzivisa makemikari akati wandei mumuviri mako anokonzera kuzvimba mumhepo yako. Ndizvo zvinonzi vanachiremba leukotriene receptor antagonist, zvinoreva kuti inoshanda zvakasiyana nemainhalers anokurumidza kubatsira aunogona kushandisa panguva yekurwiswa kweasthma.
Mushonga uyu wakagadzirirwa kudzora asthma kwenguva refu, kwete mamiriro ekukurumidzira. Funga nezvazvo sechikamu chetsika yako yezuva nezuva kuchengetedza nzira dzako dzemhepo dzakanyarara uye kuderedza mukana wezviratidzo zveasthma zvinoputika.
Zafirlukast inonyanya kunyorerwa kudzivirira zviratidzo zveasthma muvanhu vakuru nevana vane makore mashanu zvichikwira. Zvinonyanya kubatsira vanhu vanowana asthma inokonzerwa neallergens senge pollen, dust mites, kana pet dander.
Chiremba wako anogona kukurudzira zafirlukast kana uri kubata neasthma inoramba ichida manejimendi ezuva nezuva. Inogona kunyanya kubatsira vanhu vane allergic rhinitis (hay fever) pamwe chete neasthma yavo, sezvo ichigadzirisa dzimwe nzira dzakafanana dzekuzvimba.
Vamwe vanachiremba vanonyorawo zafirlukast off-label ye exercise-induced asthma, kunyangwe izvi zvisiri zvaro rekutanga rakabvumirwa. Mushonga unoshanda zvakanyanya kana uchitorwa nguva dzose sechikamu chechirongwa chakazara cheasthma manejimendi.
Zafirlukast inoshanda nekudzivisa leukotrienes, ayo ari makemikari echisikigo anogadzirwa nemuviri wako panguva yekugadzirisa allergic uye kuzvimba. Makemikari aya anoita kuti tsandanyama dzemhepo yako dzisungane uye dzinowedzera kugadzirwa kwemucus, zvichiita kuti zvinyanye kufema.
Nekudzivisa ma leukotrienes aya, zafirlukast inobatsira kuchengetedza nzira dzako dzemhepo dzakanyanya kuzorora uye dzisina kuzvimba. Izvi zvakasiyana nebronchodilators (senge albuterol) anokurumidza kuvhura nzira dzemhepo panguva yekurwiswa, kana corticosteroids inoderedza kuzvimba zvakanyanya.
Mushonga uyu unoonekwa seunoshanda zvine mwero pakudzora asthma. Kunyange zvisina simba semishonga inofemwa ye corticosteroids, inogona kuva sarudzo yakanaka kune vanhu vane matambudziko ne inhalers kana vanoda rubatsiro rwakawedzerwa kupfuura kurapwa kwavo kwazvino.
Tora zafirlukast sezvinorayirwa nachiremba wako, kazhinji kaviri pazuva maawa anenge gumi nemaviri akasiyana. Chinhu chakakosha kurangarira kutora mudumbu risina chinhu, awa rimwe risati rasvika kudya kana maawa maviri mushure mekudya.
Chikafu chinogona kuderedza zvakanyanya kuti muviri wako unotora sei mushonga, saka nguva yekudya inokosha. Kana uchizvitora kaviri pazuva, unogona kutora dose imwe mangwanani musati madya uye imwe manheru musati madya dinner kana panguva yekurara.
Medza mahwendefa ese nemvura yakawanda. Usapwanye, kutsenga, kana kuapwanya. Kana uine dambudziko rekumedza mahwendefa, taura nachiremba wako nezve dzimwe nzira pane kuedza kuagadzirisa iwe pachako.
Ramba uchitora zafirlukast kunyangwe ukanzwa zvakanaka. Sezvo iri mushonga wekudzivirira, kuumisa paunonzwa zviri nani kunogona kutungamira kudzoka kwezviratidzo zveasthma mukati memazuva mashoma kusvika kumavhiki.
Zafirlukast kazhinji mushonga wenguva refu waunozotora kwenguva yakareba sezvaunoda kudzora asthma. Vanhu vazhinji vanozvitora kwemwedzi kana makore, zvichienderana nekukomba kweasthma yavo uye kuti dzimwe nzira dzekurapa dzinoshanda sei.
Unogona kuona kumwe kuvandudzwa muzviratidzo zvako zveasthma mukati memazuva mashoma kusvika kumavhiki maviri ekutanga kurapwa. Zvisinei, zvinogona kutora kusvika kumavhiki mana kuti uwane zvizere zvemushonga.
Chiremba wako achatarisa nguva dzose kana zafirlukast ichiri sarudzo yakakodzera kwauri. Vanogona kugadzirisa dose yako, kuwedzera mamwe mishonga, kana kuchinjira kune dzimwe nzira dzekurapa zvichienderana nekuti asthma yako inodzorwa sei uye chero mhedzisiro yaunosangana nayo.
Vanhu vazhinji vanotsungirira zafirlukast zvakanaka, asi semishonga yese, inogona kukonzera matambudziko. Kunzwisisa zvaunotarisira kunogona kukubatsira kuti unzwe wakavimbika pamusoro pekurapa kwako.
Matambudziko anowanzoitika ayo vanhu vazhinji vanowana anosanganisira:
Matambudziko aya anowanzoita akapfava uye anowanzoita nani muviri wako paunojaira mushonga mumavhiki mashoma ekutanga.
Matambudziko asingawanzoitiki asi akakomba anoda kutariswa kwekurapa nekukurumidza. Izvi zvinosanganisira:
Kazhinji, vamwe vanhu vanowana mamiriro anonzi Churg-Strauss syndrome, iyo inosanganisira kuzvimba kwemidzi yeropa. Zviratidzo zvekutanga zvinosanganisira kuwedzera kweasthma, matambudziko e sinus, rash, kana kupera mitezo mumaoko netsoka.
Kana ukaona chero zviratidzo zvinokunetsa, usazeza kubata chiremba wako. Vanogona kubatsira kuona kana zviratidzo zvacho zvichikonzerwa nemushonga uye matanho ekutora anotevera.
Zafirlukast haisi yemunhu wese, uye chiremba wako achanyatso funga nezve nhoroondo yako yekurapa asati akuraira. Hau faniri kutora mushonga uyu kana uine allergic ku zafirlukast kana chero zvinhu zvaro.
Vanhu vane chirwere chechiropa vanoda kufungwa zvakakosha, sezvo zafirlukast kazhinji inogona kukonzera matambudziko echiropa. Chiremba wako anogona kuraira bvunzo dzeropa kuti aongorore basa rechiropa chako usati watanga kurapwa uye nguva nenguva paunenge uchitora.
Kana wakaita pamuviri kana kuti uri kuyamwisa, kurukurai njodzi nemabhenefiti nachiremba wenyu. Kunyange zvazvo zafirlukast isina kuratidzwa zvachose kuti inokuvadza panguva yekuzvitakura, hapana tsvakurudzo yakakwana yekusimbisa kuchengeteka kwayo kwakakwana.
Vana vari pasi pemakore mashanu havafaniri kutora zafirlukast, sezvo kuchengeteka kwayo nekushanda kwavo zvisina kumiswa muboka rezera iri. Kune vana vane makore mashanu zvichikwira, vanachiremba vachaverenga zvakanyatsonaka muyero wakakodzera zvichienderana nezvinodiwa nemwana nekupindura kwavo.
Zafirlukast inowanikwa pasi pezita rebrand Accolate muUnited States. Iyi ndiyo fomu yemushonga inonyanya kunyorerwa uye inouya mumahwendefa e10mg ne20mg.
Mhando dzegeneric dzezafirlukast dziripowo, dzine chinhu chimwe chete chinoshanda sevhersi yebrand name. Izvi zvingasarudzwa zvegeneric zvinogona kuve zvakachipa uku vachipa mabhenefiti akafanana ekurapa.
Kunyangwe iwe wakanyorerwa zita rebrand kana vhezheni yegeneric, mushonga unoshanda nenzira imwechete. Murapi wako wemishonga anogona kukubatsira kunzwisisa chero misiyano mukuonekwa kana kurongedza pakati pevagadziri vakasiyana.
Kana zafirlukast isingashande zvakanaka kwauri kana kukonzera mhedzisiro inonetsa, dzimwe nzira dzinogona kubatsira kudzora asthma yako. Chiremba wako achashanda newe kuti uwane sarudzo yakakodzera.
Zvimwe zvinogadzirisa leukotriene zvinosanganisira montelukast (Singulair), iyo inoshanda zvakafanana nezafirlukast asi inotorwa kamwe chete pazuva uye inogona kutorwa nechikafu. Vamwe vanhu vanowana montelukast iri nyore kana kuti inotsungirirwa zviri nani.
Corticosteroids inofemwa sefluticasone (Flovent) kana budesonide (Pulmicort) inowanzoonekwa seyakajairika yegoridhe yekudzora asthma. Ivo vanowanzo shanda zvakanyanya kupfuura leukotriene modifiers asi vanoda hunyanzvi hwakakodzera hwe inhaler.
Mishonga inoshanda kwenguva refu ye beta-agonists yakabatanidzwa nemishonga inofemwa ye corticosteroids, yakaita se fluticasone/salmeterol (Advair) kana budesonide/formoterol (Symbicort), inopa zvese zvinopesana nekuzvimba uye bronchodilator mhedzisiro mune imwe inhaler.
Kune vanhu vane allergic asthma, sarudzo itsva dzakaita se omalizumab (Xolair) kana mamwe mishonga yebiological inogona kufungwa, kunyangwe izvi zvinowanzo chengeterwa severe asthma isingapinduri kune mamwe marapirwo.
Zvese zva zafirlukast uye montelukast zvinopesana ne leukotriene receptor antagonists zvinoshanda nenzira dzakafanana, asi zvine misiyano yakakosha inogona kuita kuti imwe ive yakakodzera kwauri pane imwe.
Montelukast ine mukana wekushandisa kamwe chete pazuva uye inogona kutorwa iine kana isina chikafu, zvichiita kuti zvive nyore kune vanhu vazhinji. Zafirlukast inoda kushandiswa kaviri pazuva uye inofanira kutorwa mudumbu risina chinhu, izvo vamwe vanhu vanowana zvakaoma kuyeuka.
Panyaya yekushanda, mishonga yese iri miviri inoonekwa seyakanyatso shanda pakudzora asthma. Zvimwe zvidzidzo zvinoratidza kuti zvinoshanda zvakaenzana pakudzivirira zviratidzo zveasthma uye kuderedza kudiwa kwe rescue inhalers.
Sarudzo pakati pavo inowanzoenderana nezvinhu zvemunhu mumwe nemumwe zvakaita sezuva rako rega rega, mamwe mishonga yaunotora, uye kuti unotsungirira sei imwe neimwe. Chiremba wako anogona kukubatsira kusarudza kuti ndeipi sarudzo inokodzera mararamiro ako uye zvinangwa zvekurapa.
Zafirlukast inowanzoonekwa seyakachengeteka kune vanhu vane chirwere chemoyo, sezvo isingakanganisi zvakananga basa remoyo semamwe mishonga yeasthma. Kusiyana nemamwe ma bronchodilators anogona kuwedzera kurova kwemoyo, zafirlukast inoshanda kuburikidza nemumwe muchina uyo usingawanzo kukanganisa basa remoyo.
Asi, kana uine chirwere chemoyo, chiremba wako achada kukutarisa zvakanyatsonaka paunotanga mushonga mutsva. Vachafunga kuti zafirlukast ingashanda sei nemishonga yako yemoyo uye kana hurongwa hwako hwese hwekurapa huchida kugadziriswa.
Kana netsaona ukatora zafirlukast yakawanda kupfuura yakarairwa, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira. Kunyange zvazvo kuwandisa kuchiwanzika, kutora zvakawanda kunogona kuwedzera njodzi yako yemigumisiro, kunyanya dumbu rinogumbuka uye kurwadziwa nemusoro.
Usaedze kutsiva kuwandisa nekusvetuka mushonga wako unotevera. Pane kudaro, dzokera kuhurongwa hwako hwekurapa sezvakarairwa nachiremba wako. Chengeta bhodhoro remushonga newe paunotsvaga rubatsiro kuitira kuti nyanzvi dzezvekurapa dzizive chaizvo zvawakatora uye zvakawanda sei.
Kana ukakanganwa kutora mushonga wezafirlukast, tora paunorangarira, chero zvakadaro uri mudumbu risina chinhu. Kana yava nguva yekutora mushonga wako unotevera, svetuka mushonga wakakanganwa uye uenderere mberi nehurongwa hwako hwenguva dzose.
Usambofa wakatora mishonga miviri panguva imwe chete kuti utsigire mushonga wakakanganwa, sezvo izvi zvinogona kuwedzera njodzi yako yemigumisiro. Kana uchikanganwa mishonga kazhinji, funga nezvekuseta zviyeuchidzo zvefoni kana kushandisa chirongwa chemapiritsi kuti zvikubatsire kuti urambe uri munzira.
Unofanira kungomira kutora zafirlukast pasi pekutungamirirwa nachiremba wako. Sezvo iri mushonga wekudzivirira, kuumisa kamwe kamwe kunogona kukonzera zviratidzo zveasthma kudzoka mukati memazuva mashoma kusvika kumavhiki, kunyangwe kana wanga uchinzwa zvakanaka.
Chiremba wako angakurudzira kumisa zafirlukast kana asthma yako yakadzorwa zvakanaka kwenguva yakareba, kana uri kusangana nemigumisiro inonetsa, kana vachida kuyedza imwe nzira yekurapa. Vangangove vachakuitisa kuti umire zvishoma nezvishoma vachitarisa zviratidzo zvako zvakanyanya.
Hongu, zafirlukast inowanzo shandiswa pamwe chete nemimwe mishonga yeasthma sechikamu chechirongwa chakazara chekurapa. Inogona kushandiswa zvakachengeteka pamwe chete nemishonga inofemwa ye corticosteroids, bronchodilators inoshanda kwenguva pfupi yekushandisa pakununura, uye mazhinji emimwe mishonga yeasthma.
Zvisinei, mimwe mishonga inogona kuita interaction ne zafirlukast, kunyanya mishonga inotetesa ropa yakaita se warfarin. Nguva dzose udza chiremba wako nemu pharmacist nezve mishonga yose yaunotora, kusanganisira mishonga isingatengeswe nechiremba uye zvinowedzerwa, kudzivirira kusangana kunogona kuitika.