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Chii chinonzi Zidovudine: Zvayakashandiswa, Madosi, Migumisiro Yakaipa nezvimwe

Created at:1/13/2025

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Zidovudine mushonga unopesana nehutachiona unobatsira kurwisa HIV, hutachiona hunokonzera AIDS. Kana ichipiwa kuburikidza neIV (intravenous nzira), inopa mushonga zvakananga muropa rako kuti uwane kurapwa nekukurumidza uye kunodzorwa.

Mushonga uyu ndeweboka rinonzi nucleoside reverse transcriptase inhibitors, rinoshanda nekudzivirira HIV kubva pakuzvinyora mumuviri wako. Kunyange zvazvo isingagoni kurapa HIV, zidovudine inobatsira kunonotsa hutachiona uye kudzivirira immune system yako kubva mukukuvadzwa zvakanyanya.

Chii chinonzi Zidovudine?

Zidovudine ndemumwe wemishonga yekutanga yeHIV yakambogadzirwa, uye inoramba iri chishandiso chakakosha mukurapa HIV nhasi. Fomu reintravenous rinoreva kuti mushonga unoenda zvakananga mutsinga yako kuburikidza netube diki kana tsono.

Vashandi vehutano vanowanzo shandisa IV zidovudine kana iwe usingakwanise kutora mapiritsi nemuromo kana pavanoda kuona mazinga chaiwo emishonga muropa rako. Izvi zvinogona kuitika kana uri muchipatara, uchiitirwa kuvhiyiwa, kana uchibata nekurwadziwa kwakanyanya kunokutadzisa kuchengeta mishonga yemuromo pasi.

Fomu reIV rinoshanda nekukurumidza kupfuura mapiritsi nekuti rinopfuura zvachose hurongwa hwako hwekugaya. Iyi nzira yakananga inogona kubatsira zvakanyanya panguva dzekurapa dzakakosha kana pakutanga kurapwa kweHIV kekutanga.

Chii chinonzi Zidovudine Chinoshandiswa?

Zidovudine IV inonyanya kushandiswa kurapa hutachiona hweHIV sechikamu chekurapa pamwe chete nemimwe mishonga yeHIV. Inoshandiswawo kudzivirira kupararira kweHIV kubva kumai kuenda kumwana panguva yekuzvitakura nekuzvara.

Chiremba wako angakurudzira IV zidovudine kana iwe uchangobva kuongororwa uine HIV uye uchida kurapwa nekukurumidza, kana kana uchichinja kubva kumishonga yemuromo kwenguva pfupi. Zvipatara zvinowanzoishandisa kune varwere vasingakwanise kumedza mapiritsi nekuda kwekurwara kana maitiro ekurapa.

Mune dzimwe nguva, vanopa hutano vanoshandisa zidovudine IV kudzivirira hutachiona hweHIV mushure mekusangana netsaona, senge kukuvara nekubaiwa netsono kuvashandi vehutano. Kurapa uku, kunonzi post-exposure prophylaxis, kunoshanda zvakanaka kana kwatanga mukati meawa mashoma ekusangana.

Zidovudine Inoshanda Sei?

Zidovudine inoshanda nekunyengedza HIV kuti ishandise zvivakwa zvekunyepedzera painoedza kuzvinyoresa. Fungidzira sekupa hutachiona zvikamu zvakaremara painoedza kuvaka makopi matsva ayo pachayo.

HIV inoda enzyme inonzi reverse transcriptase kuti ibereke mukati memaseru ako. Zidovudine inoita seyakaenzana neimwe yezvivakwa zvakasikwa zvinodiwa neHIV, saka hutachiona hunoishandisa netsaona panzvimbo payo. Kana hutachiona hwakabatanidza zidovudine, haigoni kupedzisa maitiro ekukopa uye inofa.

Mishonga iyi inoonekwa seyepakati pesimba munyika yekurapa HIV. Haisi iyo itsva kana iyo ine simba rakawanda iripo, asi yakaratidza kushanda kana ichishandiswa nemimwe mishonga yeHIV. Nzira yekubatanidza inobatsira kudzivirira hutachiona kubva pakugadzira kuramba kumishonga imwe chete.

Ndinofanira Kutora Sei Zidovudine?

Sezvo zidovudine IV ichipiwa zvakananga muropa rako, haufanire kunetseka nezvekuitora nechikafu kana mvura semishonga yemuromo. Chikwata chako chehutano chichabata ruzivo rwese rwekutonga iwe.

Mishonga inowanzo kupiwa se infusion inononoka kwemaawa 1-2 kuburikidza neIV line. Mukoti wako achakutarisa panguva ye infusion kuti atarise chero maitiro ekukasira kana mhedzisiro.

Haufanire kudzivisa chero chikafu chakati wandei uchigamuchira zidovudine IV, kunyangwe kuchengetedza chikafu chakanaka kunobatsira kutsigira hutano hwako hwese panguva yekurapa HIV. Kunwa mvura yakawanda kunogona kubatsira itsvo dzako kugadzirisa mishonga zvakanyanya.

Ndinofanira Kutora Zidovudine Kwenguva Yakareba Sei?

Kureba kwemishonga ye zidovudine IV kunoenderana zvachose nemamiriro ako chaiwo uye zvaunoda zvekurapa. Vamwe vanhu vanoiwana kwemazuva mashoma chete pavanenge vari muchipatara, asi vamwe vangada kuishandisa kwemavhiki akati wandei.

Kana uri kushandisa zidovudine IV nekuti haugone kutora mishonga yemuromo kwenguva pfupi, ungangodzokera kumapiritsi kana wanzwa zviri nani. Chiremba wako achasarudza nguva yakakodzera zvichienderana nekupora kwako uye kugona kuchengeta mishonga yemuromo pasi.

Kudzivirira kutapurirana kweHIV kubva kuna amai kuenda kumwana, kurapwa kunowanzoenderera mberi kuburikidza nekushanda nekuzvara. Post-exposure prophylaxis inowanzoita mazuva makumi maviri nemasere ekurapa, kunyangwe izvi zvingatanga nemadosi eIV vasati vachinja kumishonga yemuromo.

Ndezvipi Zvakaipa zveZidovudine?

Semishonga yese, zidovudine inogona kukonzera mhedzisiro, kunyangwe kwete munhu wese anoiziva. Fomu reIV rinogona kukonzera mamwe maitiro akasiyana kana richienzaniswa ne zidovudine yemuromo sezvo ichipinda muropa rako zvakananga.

Heano mhedzisiro yakajairika yaungacherechedza panguva kana mushure mekuiswa kweIV yako:

  • Kutadza uye kurutsa
  • Kutemwa nemusoro
  • Kuneta kana kunzwa kuneta zvisingaite
  • Dizziness
  • Kutambudzika kurara
  • Kurwadziwa kwemhasuru kana kusimba
  • Kutsamwa kana kurwadziwa panzvimbo yeIV

Izvi zvinowanzoitika zvinowanzoita nani sezvo muviri wako uchigadzirisa kumishonga. Chikwata chako chehutano chinogona kubatsira kubata chero kusagadzikana kwaunowana.

Vamwe vanhu vanowana mhedzisiro yakakomba inoda kutariswa kwekurapa nekukasira. Kunyangwe izvi zvisingawanzoitiki, zvakakosha kuzviziva:

  • Kushaya ropa kwakanyanya (kuwanda kwemaseru matsvuku eropa) kunokonzera kuneta kukuru neganda rakachenuruka
  • Kushaya maseru machena eropa zvichiita kuti uve nyore kutapukirwa nezvirwere
  • Lactic acidosis (chirwere chisingawanzoitiki asi chakakomba chinokonzera kurwadziwa kwemhasuru nekufema kwakaoma)
  • Matambudziko akakomba echiropa ane zviratidzo zvakaita seruvara yeganda kana maziso
  • Maitiro akakomba ekuita allergic ane rash, kuzvimba, kana kufema kwakaoma

Chikwata chako chekurapa chichatarisa kuwanda kweropa rako nebasa rechiropa nguva dzose kuti ubate chero matambudziko akakomba nekukurumidza. Vanhu vazhinji vanotsungirira zidovudine zvakanaka, kunyanya kana iri chikamu chechirongwa chekurapa chinotariswa zvakanyanya.

Ndiani Asingafaniri Kutora Zidovudine?

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Zidovudine haina kuchengeteka kumunhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akuraira. Vanhu vane mamiriro akati wandei vanoda kungwarira zvakanyanya kana vangada kudzivisa mushonga uyu zvachose.

Unofanira kuudza mupi wako wehutano kana uine chero mamiriro aya usati watanga zidovudine IV:

  • Kushaya ropa kwakanyanya kana zvimwe zvirwere zveropa
  • Chirwere cheitsvo kana basa reitsvo rakaderedzwa
  • Chirwere chechiropa kana hepatitis
  • Nhoroondo ye pancreatitis (kuputika kwepancreas)
  • Zvirwere zvemuviri kana kusimba kwemhasuru kusingatsananguriki
  • Maitiro ekare ekuita allergic ku zidovudine kana mishonga yakafanana

Vakadzi vane pamuviri vanogona kugamuchira zidovudine IV zvakachengeteka pasi pekutariswa kwechiremba, sezvo zvichikurudzirwa kudzivirira kupararira kweHIV kumwana. Zvisinei, chiremba wako achakutarisa iwe nemwana wako pedyo panguva yekurapa.

Kana uri kutora mamwe mishonga, kunyanya ayo anokanganisa maseru ako eropa kana chiropa, chiremba wako angada kugadzirisa zviyero kana kusarudza mamwe marapirwo. Nguva dzose ita runyorwa rwakakwana rwemishonga yese uye zvinowedzera zvauri kutora.

Zita reZidovudine Brand

Zidovudine inowanikwa pasi pemazita akati wandei emhando, Retrovir ndiyo inonyanya kuzivikanwa. Unogonawo kuiona yakanyorwa seAZT, iyo ipfupiso yezita rayo remakemikari azidothymidine.

Vagadziri vakasiyana vanogadzira mhando dze generic dze zidovudine, saka kurongedza uye chitarisiko zvinogona kusiyana zvichienderana nekuti ndeipi vhezheni inoshandiswa nechipatara chako kana kiriniki. Mushonga uri mukati unogara wakafanana zvisinei nezita remhando kana mugadziri.

Chikwata chako chehutano chichashandisa chero vhezheni iripo panzvimbo yako yekurapa. Ese maFDA-akabvumidzwa mhando dze zidovudine anosangana nemhando imwechete uye mitemo yekushanda, saka unogona kuvimba kuti uri kuwana kurapwa kwakakodzera.

Zvimwe Zvinhu Zvinotsiva Zidovudine

Mishonga yakati wandei yeHIV inogona kushanda senzira yekutsiva zidovudine, zvichienderana nezvido zvako zvakatarwa uye mamiriro ako ekurapa. Chiremba wako angangofunga nezvezvisarudzo izvi kana zidovudine isina kukodzera iwe kana kana uine matambudziko emigumisiro.

Zvimwe zvinodzivirira reverse transcriptase inhibitors zvinosanganisira emtricitabine, tenofovir, uye lamivudine. Izvi zvinoshanda zvakafanana ne zidovudine asi vane akasiyana side effect profiles uye kuramba maitiro.

Kurapa kweHIV kwemazuva ano kunowanzo shandisa makirasi akasiyana emishonga zvachose, senge integrase inhibitors kana protease inhibitors. Izvi zvingasarudzwa zvitsva zvingave zviri nyore kutora uye zvine mashoma side effects, kunyangwe sarudzo yakanakisa ichienderana nemamiriro ako ega.

Zidovudine Zviri Nani Pane Zvimwe Zvinhu Zvinorapa HIV?

Zidovudine haisi nani kana kuipa pane mamwe mishonga yeHIV - ingori imwe chishandiso mukurapa kwakazara.

Kana tichienzanisa nemishonga mitsva yeHIV, zidovudine yakagara kwenguva refu, saka vanachiremba vane ruzivo rwakawanda pamusoro pemigumisiro yayo nekudyidzana. Zvisinei, mishonga mitsva inowanzoita matambudziko mashoma uye nguva dzakakodzera dzekushandisa.

Vashandi vehutano vachafunga nezvezvinhu zvakaita sebasa remapapu ako, mamwe mamiriro ehutano, kudyidzana kwemishonga, uye rudzi rweHIV rwaunaro paunenge uchisarudza mishonga. Chinangwa nguva dzose ndechokuwana musanganiswa unoshanda zvakanyanya kwauri uine matambudziko mashoma.

Mibvunzo Inowanzo Bvunzwa Pamusoro peZidovudine

Zidovudine Yakachengeteka Kune Vanhu vane Chirwere cheItsvo Here?

Zidovudine inogona kushandiswa kune vanhu vane chirwere cheitsvo, asi inoda kunyatsoongororwa uye pamwe kugadzirisa dosi. Itsvo dzako dzinobatsira kubvisa zidovudine mumuviri wako, saka basa remapapu rakaderedzwa rinogona kukonzera kuti mushonga uwedzere kusvika kumazinga epamusoro.

Chiremba wako achatarisa basa remapapu ako nemiedzo yeropa usati watanga kurapwa uye achaironda nguva dzose paunenge uchigamuchira zidovudine IV. Vanogona kugadzirisa dosi rako kana kuwedzera nguva pakati pemadosi kudzivirira kuwanda kwemishonga.

Ndingaita Sei Kana Ndikagamuchira Zvakawanda zveZidovudine Netsaona?

Sezvo zidovudine IV ichipiwa nenyanzvi dzehutano munzvimbo inodzorwa, kuwandisa netsaona hakusi kwakajairika. Chikwata chako chekurapa chinonyatsoverenga uye chinotarisa dose yega yega kuti uve nechokwadi chekuti unogamuchira huwandu hwakakodzera.

Kana uine hanya nedosi yako kana uine zviratidzo zvisingawanzoitiki panguva yekuiswa kwako, udza mukoti wako kana chiremba wako nekukasira. Vanogona kutarisa mirairo yako yemishonga uye kugadzirisa kurapwa kwako kana zvichidikanwa. Zviratidzo zvekuwandisa zidovudine zvinogona kusanganisira kusvotwa kwakanyanya, kuneta kwakanyanya, kana kusimba kusingawanzoitiki.

Ndingaita Sei Kana Ndikakanganwa Dosi yeZidovudine?

Kusavapo kwemushonga wezidovudine IV hakuiti sezvo vashandi vezvehutano vachiuisa maererano nechirongwa chakatarwa. Zvisinei, kana kupinzwa kwako kuchinonoka kana kukanganiswa nezvikonzero zvekurapa, chikwata chako chezvehutano chichasarudza nzira yakanakisisa yekupfuurira nayo.

Vanogona kukupa mushonga wakarasika nekukurumidza sezvinobvira, kugadzirisa chirongwa chako chekupa mishonga, kana kuita dzimwe shanduko kuti uve nechokwadi chekuti unogamuchira kurapwa kwakakwana. Usambofa wakaedza "kubata" nekukumbira mishonga yakawanda - chikwata chako chekurapa chichabata chero kugadzirisa chirongwa zvakachengeteka.

Ndingamira Rini Kutora Zidovudine?

Haufanire kumira zidovudine IV wega - sarudzo iyi inofanira kugara ichiitwa nechikwata chako chezvehutano. Kumisa mishonga yeHIV kamwe kamwe kunogona kubvumira hutachiona kuti huwedzere nekukurumidza uye zvichida kuita kuramba kurapwa.

Chiremba wako achasarudza nguva yekumisa zidovudine IV zvichienderana nezvinangwa zvako zvekurapa uye mamiriro ako ehutano azvino. Kana iwe uchichinja kubva kuIV kuenda kumishonga yemuromo, vachabatana nguva kuti vave nechokwadi chekurapwa kunoenderera mberi pasina mikaha.

Ndingatyaira Here Mushure meKugamuchira Zidovudine IV?

Zidovudine inogona kukonzera dzungu uye kuneta, kunyanya paunotanga kurapwa. Hauzofaniri kutyaira kana kushandisa michina kana uchinzwa dzungu, kuneta, kana kukanganiswa mushure mekuiswa kwako.

Vanhu vazhinji vanogamuchira zidovudine IV vari muchipatara kana kiriniki zvakadaro, saka kutyaira kazhinji hakusi kunetseka kwakakurumidza. Usati waenda kunzvimbo yekurapa, ita shuwa kuti unonzwa wakangwarira uye wakatsiga patsoka dzako. Kana usina chokwadi nezvekukwanisa kwako kutyaira zvakachengeteka, kumbira mumwe munhu kuti akupe rwendo rwekuenda kumba.

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