Chii chinonzi Zileuton: Zvazvinoshandiswa, Mishonga, Zvazvinokonzeresa uye Zvimwe

Zileuton mushonga unopiwa nachiremba unobatsira kudzivirira kurwiswa kweasthma nekuderedza kuzvimba mumhepo yako. Iyo ndeyeboka remishonga inonzi leukotriene inhibitors, iyo inoshanda zvakasiyana kubva kune yakajairika yekununura inhalers kana steroids yaungave uchiziva.

Mushonga uyu hausi chinhu chaungashandisa panguva yekurwiswa kweasthma. Panzvimbo pezvo, yakagadzirirwa kutora zuva nezuva sechikamu chechirongwa chako chekuchengetedza asthma kwenguva refu, ichibatsira kuchengeta nzira dzako dzemhepo dzakanyarara uye dzisingaite nekufamba kwenguva.

Chii chinonzi Zileuton chinoshandiswa?

Zileuton inonyanya kupihwa kurapa zviratidzo zveasthma muvanhu vakuru nevana vane makore gumi nemaviri zvichikwira. Chiremba wako angakurudzira mushonga uyu kana uri kusangana neasthma flare-ups kazhinji kunyangwe uchishandisa mamwe marapirwo.

Mushonga uyu unoshanda zvakanaka kune vanhu vane asthma inoita seinokonzerwa nekurovedza muviri, mhepo inotonhora, kana maallergen senge pollen uye dust mites. Inogonawo kubatsira kana uine aspirin-sensitive asthma, rudzi rwakati rwunogona kukonzera matambudziko ekufema.

Vamwe vanachiremba vanopawo zileuton off-label kune mamwe mamiriro ekuzvimba, kunyangwe kudzivirira asthma ichiramba iri kushandiswa kwayo kukuru kwakabvumidzwa. Mupi wako wehutano achasarudza kana mushonga uyu wakakodzera mamiriro ako chaiwo uye zvaunoda kuhutano.

Zileuton inoshanda sei?

Zileuton inoshanda nekudzivisa enzyme inonzi 5-lipoxygenase mumuviri wako. Iyi enzyme inobatsira kugadzira makemikari anozvimba anonzi leukotrienes, ayo anogona kukonzera kuti nzira dzako dzemhepo dzisungane, kuzvimba, uye kugadzira mucus yakawanda.

Funga nezve leukotrienes sevagadziri venhamo mune yako yekufema system. Pavanenge vachishanda, vanoita kuti nzira dzako dzemhepo dzive sensitive uye dzinopindura kune zvinokonzeresa senge allergens kana irritants. Nekuderedza makemikari aya, zileuton inobatsira kuchengeta nzira dzako dzemhepo dzakanyatsozorodza uye dzisingaite kuti dzipindure zvakanyanya.

Mushonga uyu unoonekwa seune simba zvishoma kana uchienzaniswa nemamwe mapiritsi ekudzivirira asthma. Haukwanisi kuenzana nemamwe ma antihistamines, asi hauna simba se steroid yakawanda. Vanhu vazhinji vanoona kuti inoshanda kana ichishandiswa nguva dzose sechikamu chetsika yavo yezuva nezuva.

Ndingatora Sei Zileuton?

Zileuton inouya nenzira mbiri: mahwendefa anoburitswa nekukurumidza anotora kana kana pazuva uye mahwendefa anoburitswa kwenguva refu anotora kaviri pazuva. Chiremba wako achasarudza fomu rinoshanda zvakanyanya pachirongwa chako nezvido.

Unogona kutora zileuton uine kana usina chikafu, kunyangwe vamwe vanhu vachiona kuti zviri nyore mudumbu ravo kana zvichitorwa nechikafu chidiki kana chikafu. Kana ukasarudza vhezheni yekukurumidza-kuburitsa, edza kupatsanura zviyero zvako zvakaenzana zuva rese, senge maawa matanhatu ega ega.

Mahwendefa anoburitswa kwenguva refu anofanira kumedzwa ese uye asina kumbovhuna, kutsenga, kana kupatsanurwa. Kuita izvi kunogona kuburitsa mushonga wakawandisa kamwechete, izvo zvisina kuchengeteka. Tora zviyero zvako panguva imwechete zuva rega rega kuti ubatsire kuchengetedza mazinga akagadzikana muhurongwa hwako.

Usanetseka kana dzimwe nguva uchida kugadzirisa nguva yako neawa kana maviri. Chinhu chakakosha kuchengetedza tsika inowirirana yaunogona kunamatira kwenguva refu.

Ndingatora Zileuton Kwenguva Yakareba Sei?

Zileuton inowanzoita mushonga wenguva refu, zvinoreva kuti ungangotora mwedzi kana makore pane mavhiki mashoma. Vanhu vazhinji vanoda kuishandisa nguva dzose kuti vachengetedze mhedzisiro yayo yekudzivirira kurwisa zviratidzo zveasthma.

Unogona kutanga kuona kumwe kuvandudzwa mukati memazuva mashoma, asi zvinogona kutora kusvika kumavhiki maviri kuti unzwe mabhenefiti akazara. Kuvandudzwa uku zvishoma nezvishoma kwakajairika uye hazvireve kuti mushonga haushandi.

Chiremba wako achatarisa nguva dzose kufambira mberi kwako uye anogona kugadzirisa chirongwa chako chekurapa zvichienderana nekuti asthma yako inodzorwa sei. Vamwe vanhu vanogona pakupedzisira kuderedza chiyero chavo kana kuchinjira kune mamwe mishonga, nepo vamwe vachibatsirwa nekugara pa zileuton kwenguva refu.

Usambomira kutora zileuton kamwe kamwe usina kutanga wataura nachiremba wako. Kumira kamwe kamwe kungaita kuti zviratidzo zveasthma zvidzoke kana kutokonzera kupisa kwakanyanya.

Ndezvipi Zvakaipa Zvinoitika ZveZileuton?

Semishonga yese, zileuton inogona kukonzera zvakaipa zvinotaurika, kunyangwe vanhu vazhinji vachizvigamuchira zvakanaka. Zvakaipa zvinowanzoitika zvinowanzoita zvinyoro uye zvinowanzovandudzika sezvo muviri wako uchigadzirisa kumishonga.

Hezvino zvakaipa zvinogona kuitika, zvakakamurwa nekuti zvinowanzoitika sei:

Zvakaipa zvinowanzoitika (zvinokanganisa vanhu vanopfuura 1 muna 10):

• Kutemwa nemusoro
• Kusvotwa kana dumbu kusagadzikana
• Manyoka
• Kurwadziwa kwemhasuru kana kusava nesimba
• Dizziness

Zvakaipa zvisingawanzoitiki (zvinokanganisa 1 muna 100 vanhu):

• Kutsvuka kweganda kana kukwenya
• Matambudziko ehope kana kusarara
• Kurwadziwa muchipfuva
• Fivha
• Kuchinja mukuravira

Zvakaipa zvisingawanzoitiki asi zvakakomba (zvinokanganisa vashoma vanopfuura 1 muna 1,000 vanhu):

• Matambudziko echiropa (kushanduka yeganda kana maziso, weti yakasviba, kuneta kwakanyanya)
• Maitiro akakomba ekuita allergic (kunetsa kufema, kuzvimba kwechiso kana huro)
• Kuchinja kwemafungiro asingawanzoitiki kana kuora mwoyo
• Kurwadziwa mudumbu kwakanyanya
• Zviratidzo zveutachiona (fivha inoramba iripo, kusava nesimba kusingawanzoitiki)

Zvakaipa zvine chekuita nechiropa zvinofanirwa kutariswa zvakanyanya nekuti chiremba wako achada kuongorora kushanda kwechiropa chako nekuedzwa kweropa nguva dzose. Kuongorora uku kunowanzoitwa uye kunobatsira kubata chero matambudziko nekukurumidza kana achigadziriswa zvakanyanya.

Zvakaipa zvakawanda zvinogadzirisika uye hazvidi kumisa mishonga. Zvisinei, taura nachiremba wako kana uine zviratidzo zvinoramba zviripo kana zvinonetsa.

Ndiani Asingafaniri Kutora Zileuton?

Zileuton haikodzeri munhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yezvokurapa asati akuraira. Mushonga uyu ungave usingakodzere kwauri kana uine mamwe mamiriro ehutano kana kutora mishonga yakati wandei.

Haufanire kutora zileuton kana uine chirwere chechiropa chiri kushanda kana ma enzymes echiropa akakwira zvakanyanya. Sezvo mushonga uyu unogona kukanganisa basa rechiropa, kutanga nechiropa chakatoita dambudziko zvinogona kuva njodzi.

Vanhu vane nhoroondo yekugadzirisa kwakanyanya kune zileuton kana chero chimwe chezvinhu zvayo vanofanira kudzivisa mushonga uyu. Uyezve, kana iwe wakazvitakura kana kuyamwisa, kurukura njodzi nemabhenefiti zvakanyatsonaka nachiremba wako, sezvo data rekuchengeteka mumamiriro ezvinhu aya rakaganhurirwa.

Zileuton inogona kuita pamwe chete nemimwe mishonga, kusanganisira warfarin (mutete weropa), theophylline (imwe mishonga yeasthma), uye mamwe mishonga yekubata mapundu. Chiremba wako achada kugadzirisa zviyero kana kukutarisa zvakanyanya kana ukatora chero izvi.

Vana vari pasi pemakore gumi nemaviri havafaniri kutora zileuton, sezvo kuchengeteka kwayo nekushanda kwavo zvisina kumiswa muboka rezera iri. Chiremba wako wevana anogona kukurudzira dzimwe nzira dzakakodzera kuvana vadiki vane asthma.

Mazita eZileuton Brand

Zileuton inowanikwa pasi pezita rekuti Zyflo, ine vhezheni yakawedzerwa-kusunungurwa inonzi Zyflo CR. Zvose zvine chinhu chimwe chete chinoshanda asi zvakagadzirirwa zvakasiyana zvemaitiro akasiyana ekushandisa.

Mavhezheni eGeneric eziileuton anowanikwawo, ayo ane chinhu chimwe chete chinoshanda asi anogona kutaridzika zvakasiyana kana kubva kune vagadziri vakasiyana. Murapi wako wemishonga anogona kukubatsira kunzwisisa kuti ndeipi vhezheni yaunogamuchira uye kuona kuti uri kuitora nemazvo.

Kunyangwe iwe ukashandisa zita remhando kana vhezheni ye generic, mushonga unoshanda nenzira imwechete. Vamwe vanhu vanosarudza imwe pane imwe zvichienderana nemutengo, inishuwarenzi, kana zvaunofarira pachako maererano nehukuru hwepiritsi kana chimiro.

Zileuton Zvimwe Zvinhu

Kana zileuton isingashandi zvakanaka kwauri kana kukonzera matambudziko, mishonga yakati wandei inogona kukubatsira kudzivirira zviratidzo zveasthma. Chiremba wako anogona kukubatsira kuongorora sarudzo idzi zvichienderana nezvido zvako.

Zvimwe zvinodzivirira leukotriene zvinosanganisira montelukast (Singulair) uye zafirlukast (Accolate). Izvi zvinoshanda zvakafanana ne zileuton asi zvinogona kuva nemigumisiro yakasiyana kana nguva yekushandisa iyo inokodzera mararamiro ako.

Mishonga inofemwa ye corticosteroids yakaita se fluticasone (Flovent) kana budesonide (Pulmicort) inowanzoonekwa seyekutanga kurapa kudzivirira asthma. Mishonga iyi inotumirwa zvakananga kumapapu ako uye inogona kushanda zvakanyanya nemigumisiro mishoma.

Kune vanhu vane asthma yakakomba, mishonga mitsva yebiological yakaita se omalizumab (Xolair) kana dupilumab (Dupixent) inogona kuva sarudzo. Izvi zvinowanzo chengeterwa zviitiko uko kumwe kurapwa kusina kupa kutonga kwakakwana.

Zvinobatanidza inhalers zvine steroid uye bronchodilator inoshanda kwenguva refu inogona zvakare kuva dzimwe nzira dzinoshanda, ichipa nyore uye yakazara asthma manejimendi muchishandiso chimwe chete.

Zileuton Zviri Nani Pane Montelukast Here?

Zvese zileuton uye montelukast zvinodzivirira leukotriene, asi zvinoshanda zvishoma zvakasiyana uye zvine zvakanakira zvakasiyana. Sarudzo yakanaka inoenderana nemamiriro ako ega, kushivirira kwemigumisiro, uye zvaunofarira.

Montelukast inotorwa kamwe chete pazuva, zvichiita kuti zvive nyore kupfuura mazhinji ezuva nezuva e zileuton. Inowanikwawo kuvana vane makore 6 mwedzi uye ine kushamwaridzana kushoma nemimwe mishonga.

Zvisinei, zileuton inogona kushanda zvakanyanya kune vamwe vanhu, kunyanya avo vane aspirin-sensitive asthma. Zvimwe zvidzidzo zvinoratidza kuti zileuton inogona kupa kutonga kuri nani kwezvimwe zviratidzo zveasthma, kunyangwe mhinduro dzemunhu dzichisiyana zvakanyanya.

Chinhu chikuru chinokanganisa zileuton kana ichienzaniswa nemontelukast ndiko kuda kuongororwa chiropa nguva dzose uye kushandisa mushonga kakawanda. Montelukast yakabatana nekuchinja kwemafungiro kune vamwe vanhu, nepo zvinhu zvikuru zvinonetesa zve zileuton zvichibatanidzwa nebasa rechiropa.

Chiremba wako achafunga nezve nhoroondo yako yezvokurapa, mararamiro ako, uye kuoma kweasthma paanenge achisarudza pakati pemishonga iyi. Dzimwe nguva, chinhu chinoshanda zvakanaka kune mumwe munhu chingasava chakanaka kune mumwe, kunyangwe aine maitiro easthma akafanana.

Mibvunzo Inowanzo Bvunzwa Pamusoro peZileuton

Zileuton Yakachengeteka Here Kune Zvirwere Zvemwoyo?

Zileuton inowanzofungidzirwa kuva yakachengeteka kune vanhu vane zvirwere zve mwoyo, sezvo isingawanzo kukanganisa rhythm yemwoyo kana blood pressure. Zvisinei, cardiologist yako ne pulmonologist vanofanira kubatana mukutarisira kwako kuti vave nechokwadi chekuti mishonga yako yose inoshanda zvakanaka pamwe chete.

Vamwe vanhu vane zvirwere zve mwoyo vanotora blood thinners, iyo inogona kushamwaridzana ne zileuton. Chiremba wako achatarisa nguva dzako dzekuumbwa kweropa zvakanyanya uye anogona kuda kugadzirisa madosi emishonga yako zvinoenderana.

Kana uine asthma uye chirwere chemwoyo, kudzora asthma yako nemishonga yakaita se zileuton kunogona kubatsira mwoyo wako nekuderedza kushushikana kunokonzerwa nematambudziko ekufema pane yako cardiovascular system.

Ndingaita Sei Kana Ndikashandisa Zileuton Yakawandisa Netsaona?

Kana netsaona ukatora zileuton yakawanda kupfuura yakarairwa, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira. Kunyange zvazvo overdoses dzisingawanzoitiki, kutora yakawanda kunogona kuwedzera njodzi yako yezvinetso, kunyanya matambudziko echiropa.

Usaedze "kugadzirisa" overdose nekusvetuka dose yako inotevera. Pane kudaro, tevera gwara remupi wako wehutano panguva yekutangazve chirongwa chako chekushandisa mushonga.

Zviratidzo zvaungave wakatora zvakawanda zvinosanganisira kusvotwa kwakanyanya, kurutsa, kuneta zvakanyanya, kana kuvhiringidzika. Tsvaga rubatsiro rwekurapa nekukasira kana uine chero zviratidzo izvi mushure mekutora mushonga wakawedzerwa.

Ndingaita Sei Kana Ndakanganwa Mushonga weZileuton?

Kana ukakanganwa kutora mushonga wezileuton, tora paunorangarira, kunze kwekunge yava nguva yekutora mushonga unotevera. Kana zvakadaro, siya mushonga wakakanganwa wotora wako wenguva dzose.

Usambofa wakatora mishonga miviri panguva imwe chete kuti ugadzirise wakakanganwa, nekuti izvi zvinogona kuwedzera njodzi yekuwana mhedzisiro. Kana uri kutora mushonga unotora nguva refu kuti ushande, izvi zvinonyanya kukosha kuti uzvidzivise.

Kana uchikanganwa mishonga kazhinji, funga nezvekuisa zviyeuchidzo pafoni yako kana kushandisa chirongwa chemishonga. Kushandisa zuva nezuva nguva dzose kwakakosha kuti zileuton ishande zvakanaka mukudzivirira zviratidzo zveasthma.

Ndingamira Rini Kutora Zileuton?

Unofanira kungomira kutora zileuton pasi pekutariswa kwachiremba wako. Vanhu vazhinji vanoda kuenderera mberi nemushonga kwenguva refu kuti vachengetedze mhedzisiro yayo yekudzivirira zviratidzo zveasthma.

Chiremba wako anogona kufunga kumisa kana kuderedza zileuton kana asthma yako yakadzorwa zvakanaka kwenguva yakareba, kana ukawana mhedzisiro isingashiviriki, kana kana mamwe marapirwo achiratidza kushanda zvakanyanya mumamiriro ako ezvinhu.

Sarudzo yekumisa ichavakirwa pakudzora kwako asthma, mamwe mishonga yaunotora, uye njodzi dzako dzega. Usambomira kamwe kamwe, nekuti izvi zvinogona kukonzera kudzoka kwezviratidzo kana kukonzera kuputika kweasthma.

Ndingatora Zileuton Panguva Yekuzvitakura Here?

Kuchengeteka kweZileuton panguva yekuzvitakura hakuna kunyatsojekeswa, saka chiremba wako achayerera zvakanaka mabhenefiti pamwe nenjodzi dzinogona kuitika. Asthma isingadzorwi panguva yekuzvitakura inogona kuva nenjodzi kwauri nemwana wako, saka kuchengetedza kutonga kwakanaka kweasthma kwakakosha.

Kana uri kuronga kuva nepamuviri kana kuona kuti une pamuviri uchitora zileuton, kurukura sarudzo dzako nachiremba wako weobstetrician uye pulmonologist. Vanogona kukurudzira kuchinja kumushonga une rumwe ruzivo rwekuchengetedza pamuviri.

Chikwata chako chehutano chichashanda newe kuti chiwane nzira yakachengeteka uye inoshanda yekurapa asthma yako panguva yekuzvitakura kwako, vachivimbisa hutano hwako nehuvandirwe hwemwana wako zvakachengetedzwa.