Chii chinonzi Zoster Vaccine (Shingrix): Zvazvinoshandiswa, Mishonga, Migumisiro, nezvimwe zvakawanda

Mushonga wezoster, unozivikanwa seShingrix, mushonga unoshanda zvakanyanya unokudzivirira kubva kushingles uye matambudziko ayo. Mushonga uyu unoshandisa chidimbu chidiki chevaricella-zoster virus yakasanganiswa ne adjuvant yekusimudzira immune response yako, ichibatsira muviri wako kuziva nekurwisa hutachiona hunokonzera shingles.

Kana uri pamusoro pe50 kana uine mamwe mamiriro ehutano anokanganisa immune system yako, mushonga uyu unogona kuderedza zvakanyanya njodzi yako yekuvandudza shingles neanopfuura 90%. Inoonekwa seimwe yemishonga inoshanda zvakanyanya iripo nhasi yekudzivirira mamiriro aya anorwadza.

Chii chinonzi Zoster Vaccine (Shingrix)?

Shingrix imushonga we recombinant, adjuvanted wakagadzirirwa kudzivirira shingles (herpes zoster) uye matambudziko ayo. Kusiyana nemishonga mhenyu, mushonga uyu une chete protein diki kubva kuvaricella-zoster virus, kwete hutachiona chaihwo.

Mushonga uyu unosanganisira adjuvant inonzi AS01B, iyo inoita semubatsiri anoita kuti immune system yako ipindure zvakanyanya kumushonga. Iyi musanganiswa inogadzira immune response yakasimba inogona kukudzivirira kwemakore mazhinji, kunyangwe immune system yako ichideredzwa zvakasikwa nezera.

Mushonga unopiwa sejojo mumusoro wako weruoko uye unoda zvikamu zviviri zvakaparadzirwa 2-6 mwedzi kuti uwane dziviriro yakazara.

Chii chinonzi Zoster Vaccine chinoshandiswa?

Chinangwa chikuru cheShingrix ndeche kudzivirira shingles, mamiriro eganda anorwadza anovandudzwa kana chickenpox virus ichidzokazve mumuviri wako. Mushonga uyu unokurudzirwa kuvanhu vakuru vane makore 50 zvichikwira, zvisinei nekuti vanoyeuka here kuva nechickenpox.

Kunze kwekudzivirira zvirwere zve shinguru pachazvo, mushonga uyu unodzivirirawo kubva ku postherpetic neuralgia (PHN), dambudziko rakakomba apo kurwadziwa kwemitsipa kunoramba kwenguva refu mushure mekunge rash ye shinguru yapera. Iri dambudziko rekurwadziwa kusingaperi rinogona kutora mwedzi kana makore, zvichikanganisa zvakanyanya hupenyu hwako.

Mushonga uyu unokurudzirwawo kune vanhu vakuru vane makore 19 zvichikwira vane immune systems dzakashatiswa nekuda kwezvirwere zvakaita se HIV, kurapwa kwekenza, kana kutamiswa kwemuviri. Kunyangwe uine shinguru kare, mushonga uyu unogona kubatsira kudzivirira zviitiko zveramangwana.

Mushonga we Zoster Unoshanda Sei?

Shingrix inoshanda nekudzidzisa immune system yako kuti izive uye kurwisa varicella-zoster virus zvinobudirira. Mushonga uyu une protein chaiyo (glycoprotein E) kubva kuvirus iyo immune system yako inodzidza kuziva seyekunze.

Kana yakasanganiswa ne adjuvant AS01B, iyi protein inokonzeresa mhinduro yakasimba ye immune inosanganisira antibodies uye T-cells. Dziviriro iyi mbiri yakakosha zvikuru nekuti T-cell immunity inowanzoita kudzikira nekufamba kwemakore, ndosaka vanhu vakuru vachinyanya kutapukirwa ne shinguru.

Mushonga uyu unoonekwa sewakasimba zvikuru uye unoshanda, uchipa dziviriro inodarika 90% kubva ku shinguru mumiedzo yekiriniki. Dziviriro iyi inoramba yakakwira kunyangwe muvanhu vane makore anopfuura 70, zvichiita kuti ive inoshanda zvakanyanya kupfuura mushonga wekare we live zoster usisiri kurudzirwa.

Ndingatora Sei Mushonga we Zoster?

Shingrix inopiwa sejojo mumhasuru yeruoko rwako rwekumusoro nachiremba. Haufaniri kutora nemukati mezvokudya kana mvura sezvo iri jojo, kwete mushonga wekamuromo.

Unoda zvikamu zviviri zve mushonga, nechikamu chechipiri chichipiwa 2-6 mwedzi mushure mechikamu chekutanga. Zvakakosha kupedzisa zvikamu zvese zviviri kuti uve nechokwadi chekudzivirirwa kwakanyanya. Kana iwe ukamirira kwenguva refu kupfuura mwedzi mitanhatu pakati pezvikamu, haufaniri kutangazve akateedzana - ingowana chikamu chako chechipiri nekukurumidza sezvinobvira.

Usati waenda kunosangana nachiremba, pfeka hembe dzine maoko anogona kupetwa nyore nyore. Unogona kudya zvakajairika usati wapiwa mushonga wejekiseni uye mushure mawo, uye hapana zvirambidzo zvakakosha zvekudya zvine chekuita nemushonga uyu.

Ndingatora Mushonga weZoster Kwenguva Yakareba Sei?

Mushonga wezoster imushonga unopiwa kaviri waunopedzisa mumwedzi yakati wandei, kwete mushonga unotorwa zuva nezuva. Paunogamuchira dose dzese dziri mbiri, unoonekwa seakanyatsojekeswa kurwisa shingles.

Tsvagiridzo yazvino inoratidza kuti dziviriro kubva kuShingrix inoramba yakasimba kwemakore angangoita 7 mushure mejekiseni. Zvidzidzo zviri kuenderera mberi kuti zviwane kuti hutachiona hunogara kwenguva yakareba sei, asi ungangoda majekiseni ekuwedzera kwemakore mazhinji, kana zvachose.

Kusiyana nemamwe majekiseni anoda majekiseni ekuwedzera gore negore, mhinduro yakasimba yekudzivirira inogadzirwa neShingrix inoita seinoita dziviriro inogara kwenguva refu. Mupi wako wehutano achakuchengeta uchiziva nezvekukurudzirwa kwemajekiseni ekuwedzera ramangwana sezvo tsvagiridzo yakawanda ichiwanika.

Ndezvipi Zvipingamupinyi zveMushonga weZoster?

Vanhu vazhinji vanowana zvimwe zvidiki kusvika pakati nepakati zvipingamupinyi mushure mekuwana Shingrix, izvo chaizvo zvinoratidza kuti immune system yako iri kupindura zvakanaka kumushonga. Zvipingamupinyi izvi zvinowanzo gara mazuva 2-3 uye zvinowanzo manejwa nemishonga yekurwadziwa inotengeswa pasina mushonga.

Heano zvipingamupinyi zvakajairika zvaungasangana nazvo, zvakarongeka kubva kune zvakanyanya kuenda kune zvishoma:

• Kurwadziwa, kutsvuka, kana kuzvimba panzvimbo yekujekiseni (kunobata vanhu vanenge 8 kubva pa10)
• Kurwadziwa kwemhasuru nekuneta (kunobata vanhu vanenge 4-5 kubva pa10)
• Kutemwa nemusoro (kunobata vanhu vanenge 4 kubva pa10)
• Fivha nekutonhora (kunobata vanhu vanenge 2-3 kubva pa10)
• Kusvotwa uye dumbu rinogumbuka (rinobata vanhu vanenge 1-2 kubva pa10)

Mhinduro idzi dzinowanzo kuve dzakasimba mushure mejekiseni rechipiri uye dzinowanzoonekwa muvanhu vakuru vadiki. Kunyangwe zvisinganzwisisike, izvi zviratidzo zvekuti immune system yako iri kuvaka dziviriro kubva kuzvirwere zveshingles.

Mhedzisiro yakakomba haisi kazhinji asi inogona kusanganisira mhinduro dzakakomba dzekurwara. Kana iwe ukawana dambudziko rekufema, kuzvimba kwechiso chako kana huro, kana hives yakakomba, tsvaga rubatsiro rwekurapa nekukurumidza. Vamwe vanhu vanogonawo kuwana kukuvara kwepafudzi kunoenderana nekupa jekiseni (SIRVA), kunyangwe izvi zvisingawanzoitiki kana jekiseni richipihwa nemazvo.

Ndiani Asingafaniri Kutora Mushonga weZoster?

Vanhu vakuru vazhinji vanogona kugamuchira Shingrix zvakachengeteka, asi pane zvimwe zvakakosha. Hau faniri kuwana mushonga uyu kana wakambove nemhinduro yakakomba yekurwara kune chero chikamu chemushonga kana kune imwe dose yeShingrix.

Unofanirwawo kudzivisa mushonga uyu kana iwe uchinetseka nekurwara kwepakati nepakati nekupisa. Kunyangwe kutonhora kudiki kusingadzivise kubaiwa jekiseni, zviri nani kumirira kusvikira wanzwa zviri nani kuti uve nechokwadi chekuti unogona kuongorora nemazvo chero mhedzisiro inokonzerwa nemushonga.

Kana iwe uri nepamuviri kana kuyamwisa, unofanirwa kumirira kuti ugamuchire Shingrix kusvikira mushure mekupera kwepamuviri nekuyamwisa. Kunyangwe pasina humbowo hwekukuvadza, hapana data rakakwana rekuchengetedza muvakadzi vane pamuviri kuti vakurudzire kushandiswa kwenguva dzose.

Vanhu vari kutora mishonga inodzvinyirira zvakanyanya immune system vanofanirwa kukurukura nguva nachiremba wavo. Kunyangwe mushonga uchikurudzirwa kune vanhu vane immune system isina simba, chiremba wako anogona kuda kugadzirisa nguva zvichienderana nechirongwa chako chekurapa.

Mazita eZita reZoster Vaccine

Shingrix ndiro zita remhando yemushonga wezoster recombinant wakagadzirwa neGlaxoSmithKline (GSK). Iyi ndiyo chete mushonga wezoster unokurudzirwa neCDC kune vanhu vakuru vane makore 50 nemakore.

Unganzwawo nezve Zostavax, iyo yaive mushonga wekare wezoster wakabayiwa, asi haichawanikwi muUnited States kubva muna 2020. Kana wakambobayiwa Zostavax kare, unofanira kuramba uchibayiwa Shingrix kuti uwane dziviriro iri nani.

Paunenge uchironga nguva yako yekubayiwa, ingobvunza kuti "mushonga wezvirwere zvemapundu" kana "Shingrix" - vanachiremba vachaziva chaizvo zvauri kureva. Mafarimasi mazhinji, mahofisi evanachiremba, uye makiriniki ehutano anopa mushonga uyu.

Zvimwe Zvingashandiswa Panzvimbo ye Zoster Vaccine

Parizvino, hapana mimwe mishonga yekubayiwa panzvimbo ye Shingrix yekudzivirira zvirwere zvemapundu. Shingrix ndiyo chete mushonga wezvirwere zvemapundu unowanikwa uye unokurudzirwa muUnited States kubva Zostavax payakaregedzwa.

Kana usingakwanise kubayiwa Shingrix nekuda kweallergy kana zvimwe zvikonzero zvekurapa, hapana mimwe mishonga yekudzivirira inowanikwa. Zvisinei, kana ukawana zvirwere zvemapundu, mishonga inorwisa mavhairasi yakaita se acyclovir, valacyclovir, kana famciclovir inogona kubatsira kuderedza kuoma uye nguva yezviratidzo kana yatanga kare.

Vamwe vanhu vanobvunza nezve zvimwe zvakasikwa kana zvinowedzerwa, asi hapana zvigadzirwa zvakasikwa zvakaratidzwa kuti zvinodzivirira zvirwere zvemapundu zvine kushanda kwakafanana neShingrix. Kuchengetedza hutano hwakanaka, kubata kushushikana, uye kurara zvakakwana zvinogona kutsigira immune system yako, asi matanho aya ega haagone kupa dziviriro chaiyo inopiwa nemushonga wekubayiwa.

Ko Shingrix iri Nani Kudarika Zostavax?

Hongu, Shingrix inoshanda zvakanyanya kupfuura mushonga wekare weZostavax. Nepo Zostavax yaipa dziviriro inenge 50% kubva kuzvirwere zvemapundu muvanhu vane makore 60-69, Shingrix inopa dziviriro inopfuura 90% mumapoka ese ezera, kusanganisira avo vane makore anopfuura 70.

Shingrix inopawo dziviriro iri nani kubva ku postherpetic neuralgia, mamiriro ekurwadziwa kwenguva refu anogona kutevera zvirwere zvemapundu. Zvidzidzo zvinoratidza kuti Shingrix inoderedza njodzi yePHN neanopfuura 90%, ichienzaniswa nekuderedzwa kwe67% neZostavax.

Kudzivirirwa kubva kuShingrix kunogarawo kwenguva refu. Nepo kushanda kweZostavax kwakaderera zvakanyanya mushure memakore mashanu, Shingrix inochengetedza kushanda kwakanyanya kwemakore angangoita 7 uye zvichida kwenguva refu. Kudzivirirwa uku kwakanyanya uye kwenguva refu ndicho chikonzero nei vakuru vehutano vakatsiva Zostavax neShingrix.

Kunyangwe iwe wakambogamuchira Zostavax munguva yakapfuura, iwe unofanirwa kuwana Shingrix kuti uwane dziviriro iri nani. Unogona kugamuchira Shingrix chero nguva mushure mekuwana Zostavax - hapana nguva yekumirira inodiwa.

Mibvunzo Inowanzo Bvunzwa Nezve Zoster Vaccine

Shingrix Yakachengeteka Kune Vanhu vane Chirwere cheShuga here?

Hongu, Shingrix yakachengeteka uye yakakosha kunyanya kune vanhu vane chirwere cheshuga. Chirwere cheshuga chinogona kuita kuti immune system yako isashande zvakanaka, zvichikuita kuti utambure zvakanyanya ne shingles uye matambudziko ayo.

Vanhu vane chirwere cheshuga vanowana shingles vanogona kusangana nezviratidzo zvakanyanya uye nguva refu yekupora. Mushonga uyu unopa dziviriro yakanaka mumunhu ane chirwere cheshuga sezvazvinoita kune avo vasina, zvichiita kuti kubaiwa jekiseni rive chiyero chekudzivirira chakachenjera. Mazinga eshuga yeropa rako haafanire kukanganiswa zvakanyanya nemushonga, kunyangwe iwe uchida kuatarisa zvakanyanya kwemazuva mashoma mushure mekubaiwa jekiseni kana iwe uchiziva kuti une glucose control.

Ndoita Sei Kana Ndikagamuchira Dosi dzakawanda dzeShingrix netsaona?

Kana netsaona ukagamuchira imwe dosi yeShingrix, usavhunduka - izvi hazvikonzere kukuvadza kukuru. Bata chiremba wako kuti utaure nezve dosi yakawedzerwa uye kukurukura chero zvaunonetseka nazvo.

Unogona kusangana nemigumisiro yakanyanya kupfuura yakajairika, senge kuwedzera kurwadziwa panzvimbo yekubaiwa jekiseni kana zviratidzo zvakasimba zvakaita sefuru. Izvi zvinofanirwa kugadzirisa mukati memazuva mashoma. Chengeta rekodhi rekuti wakagamuchira rini dosi rega rega kuti uve nechokwadi chekuti pane nzvimbo yakakodzera yekubaiwa jekiseni remunguva yemberi. Chiremba wako anogona kukubatsira kuona kana chero shanduko dzichidikanwa kuchirongwa chako chekubaiwa jekiseni.

Ndoita Sei Kana Ndikarasikirwa neDosi yangu yechipiri yeShingrix?

Kana ukasavaka jekiseni rako rechipiri reShingrix, ronga kuti riitwe nekukurumidza sezvinobvira. Haufaniri kutangazve akatevedzana - ingoita jekiseni rako rechipiri chero paunogona, kunyangwe zvave kwenguva refu kupfuura mwedzi mitanhatu kubva pajekiseni rako rekutanga.

Nepo nguva yakakurudzirwa iri mwedzi miviri-6 pakati pejekiseni, kuwana jekiseni rechipiri gare gare kupfuura zvakarongwa hakuzoderedzi kushanda kwayo. Muromo wako wekudzivirira muviri uchiri kupindura zvakanaka kujekiseni rechipiri rakazengereka. Zvisinei, hauzovi nekudzivirirwa kwakakwana kubva kuzvirwere zvemapfupa kusvikira wapedza jekiseni rese, saka usanonoke zvisina kufanira.

Ndingamira Rini Kunetseka Nezve Zvirwere Zvemapfupa Mushure meKuwana Shingrix?

Unogona kunzwa uine chivimbo nezvekudzivirirwa kwako kwezvirwere zvemapfupa mumasvondo maviri-4 mushure mekuwana jekiseni rako rechipiri reShingrix. Uyu ndiwo muviri wako wekudzivirira muviri pawakanyatso pindura jekiseni uye wakavaka dziviriro yakanyanya.

Jekiseni rinopa dziviriro inodarika 90%, izvo zvinoreva kuti njodzi yako yekuvandudza zvirwere zvemapfupa inova yakaderera kwazvo. Zvisinei, yeuka kuti hapana jekiseni rinoshanda 100%, saka mukana mudiki wezvirwere zvemapfupa uchiripo. Kana ukavandudza zvirwere zvemapfupa mushure mejekiseni, zvinogona kunge zviri nyoro uye zvipfupi kupfuura zvaizove zvisina jekiseni.

Ndingawana Shingrix here kana ndichitora zvinoderedza ropa?

Hongu, unogona kuwana Shingrix zvakachengeteka kana uchitora zvinoderedza ropa zvakaita sewarfarin, apixaban, kana aspirin. Jekiseni rinopiwa sejekiseni remumuviri, uye kunyangwe painogona kunge paine kupwanya zvishoma panzvimbo yekujekesa, izvi hazvina njodzi.

Zivisa mupi wako wehutano nezve mishonga yako yekuderedza ropa usati wajekeswa. Vanogona kushandisa kumanikidza panzvimbo yekujekesa kwenguva yakareba kupfuura zvakajairika kuderedza kupwanya. Zvakanakira kudzivirira zvirwere zvemapfupa zvinopfuura njodzi diki yekuwanda kwemavanga, kunyanya sezvo vanhu vari pamishonga yekuderedza ropa vangave vari panjodzi huru yezvinetso zvemapfupa.