Chii chinonzi Hormone Therapy ye Kanza ye Mazamu? Chinangwa, Mhando & Mhedzisiro

Hormone therapy ye kanza ye mazamu imishonga inovharisa kana kuderedza mahomoni e estrogen ne progesterone anotsigira mamwe marudzi ekanza yemazamu. Fungidzira sekugura mafuta anobatsira makenza aya kukura. Nzira iyi yakatarwa inogona kuderedza zvakanyanya njodzi yekuti kanza idzokezve uye kubatsira kudzikisa tumor dziripo muvarwere vazhinji.

Chii chinonzi hormone therapy ye kanza yemazamu?

Hormone therapy inoshanda nekuti inovharisa ma hormone receptors pamaseru ekanza kana kuderedza huwandu hwemahomoni anogadzirwa nemuviri wako. Anenge 70% ekanza yemazamu ane hormone receptor-positive, zvinoreva kuti anoshandisa estrogen kana progesterone kukura nekuzviparadzanisa.

Mishonga iyi yakasiyana zvachose ne hormone replacement therapy iyo vamwe vakadzi vanoshandisa kune zviratidzo zvemenopause. Panzvimbo pekuwedzera mahomoni, kanza hormone therapy inobvisa kana kuvavharisa kuti inyime maseru ekanza zvavanoda kuti vararame.

Mishonga iyi inouya mumapiritsi aunotora zuva nezuva kana semajekiseni emwedzi, zvichienderana nerudzi racho rinokurudzirwa nachiremba wako. Vanhu vazhinji vanoenderera mberi nemishonga iyi kwemakore 5 kusvika ku10 kuti vawane dziviriro yakanaka pakudzoka kwekanza.

Nei hormone therapy ye kanza yemazamu ichiitwa?

Chiremba wako anokurudzira hormone therapy kudzivirira maseru ekanza kubva pakutora mahomoni avanoda kukura. Zvakafanana nekubvisa kiyi inobvumira kanza kuvhura nekuzviparadzanisa mumuviri wako.

Zvinangwa zvikuru zvinosanganisira kuderedza njodzi yako yekuti kanza idzokezve mushure mekuvhiyiwa, kudzikisa tumor pamberi pekuvhiyiwa kuti kubviswa kuve nyore, uye kunonotsa kukura kwekanza kana yakapararira kune dzimwe nhengo dzemuviri wako.

Mishonga iyi inoshanda chete kune hormone receptor-positive breast cancers. Chirevo chako chepathology mushure mebiopsy kana kuvhiyiwa chicharatidza kana kanza yako iine estrogen receptors (ER-positive) kana progesterone receptors (PR-positive).

Ndeipi nzira ye hormone therapy?

Mishonga yakawanda yema hormone inosanganisira kutora piritsi zuva nezuva kumba, zvichiita kuti zvive nyore zvakanyanya kupfuura chemotherapy inoda kushanya kuchipatara. Chiremba wako achasarudza mushonga chaiwo unoshanda zvakanyanya kune mamiriro ako.

Kune vakadzi vasati vapinda mu menopause, kurapwa kazhinji kunotanga nekudzivirira kwemwedzi nemwedzi kumisa mazai ako kubva pakugadzira estrogen, yakasanganiswa nemapiritsi ezuva nezuva. Vakadzi vakapinda mu menopause vanowanzo tora mapiritsi ezuva nezuva anovharisa kugadzirwa kwe estrogen mune mamwe matishu emuviri.

Chikwata chako chekurapa chichakutarisa nguva dzose kuburikidza nemiedzo yeropa uye kuongororwa kuti uve nechokwadi chekuti kurapwa kuri kushanda nemazvo uye kubata chero mhedzisiro. Misangano iyi inowanzoitika mwedzi mitatu kusvika kumwedzi mitanhatu panguva yekurapa kwako.

Maitiro ekugadzirira kurapwa kwako kwema hormone?

Kugadzirira kurapwa kwema hormone kunotanga nekunzwisisa zvekutarisira uye kuunganidza rutsigiro kubva kuchikwata chako chehutano. Chiremba wako achatarisa nhoroondo yako yekurapa uye mishonga iripo kudzivirira chero kusangana kunotyisa.

Iwe uchada bvunzo dzekutanga dzinosanganisira kuongororwa kwepfupa, mazinga echolesterol, uye bvunzo dzebasa rechiropa usati watanga kurapwa. Izvi zvinobatsira chiremba wako kutarisa kuti kurapwa kunokanganisa sei muviri wako nekufamba kwenguva.

Funga nezvekukurukura nzira dzekugadzirisa mhedzisiro nechikwata chako chehutano usati watanga. Kuva nechirongwa chezvinhu zvakajairika zvakaita semoto unopisa, kurwadziwa kwemajoini, kana shanduko dzemanzwiro zvinogona kukubatsira kuti unzwe wakagadzirira uye wakavimbika nezvekufamba kwako kwekurapa.

Maitiro ekuverenga mhedzisiro yako yekurapa kwema hormone?

Chiremba wako anotevera kubudirira kwekurapa kwema hormone kuburikidza nekuongororwa kwemifananidzo nguva dzose, bvunzo dzeropa, uye bvunzo dzemuviri panzvimbo yemhedzisiro imwe chete yebvunzo. Chinangwa ndechekuona bundu rakagadzikana kana kudzikira kana uine gomarara rinoshanda, kana kungoramba usina gomarara kana uri mumaitiro ekudzivirira.

Miedzo yeropa inotarisa mazinga ako emahormone kuti ave nechokwadi chekuti mushonga uri kuvharisa estrogen ne progesterone zvinobudirira. Chiremba wako achatarisawo kushanda kwechiropa sezvo mishonga iyi ichigadziriswa nechiropa chako.

Kutariswa kwemafupa kunokosha nekuti kurapwa nemahormone kunogona kuita kuti mapfupa asakare simba nekufamba kwenguva. Chiremba wako anogona kukurudzira calcium uye mavitamini D supplements kana mishonga yekusimbisa mapfupa kana zvichidikanwa.

Nzira yekugadzirisa mativi emishonga ye hormone therapy?

Kugadzirisa mativi emishonga kunosanganisira kushanda pedyo nechikwata chako chehutano kuti uwane mhinduro dzinokuchengeta wakasununguka uchiramba uchirapa kenza yako yakakosha. Mazhinji emativi emishonga anogadziriswa nekushandisa nzira yakarurama.

Mativi emishonga akajairika uye nzira dzekugadzirisa dzinosanganisira:

• Kupisa kwemuviri: Pfeka mbatya dzakaturikidzana, shandisa mafeni ekutonhodza, edza nzira dzekuzorora, kana kubvunza nezvemishonga inogona kubatsira
• Kurwadziwa mumajoini uye kuoma: Kujairika kurovedza muviri zvinyoro-nyoro, physiotherapy, mabhazi anodziya, kana mishonga inorwisa kuzvimba
• Kuchinja kwemanzwiro: Counseling, mapoka ekutsigira, nzira dzekugadzirisa kushushikana, kana antidepressants kana zvichidikanwa
• Kuneta: Kufamba-famba, nguva yekurara yakajairika, kurovedza muviri zvishoma, uye nzira dzekuchengetedza simba
• Kuoma kwevagina: Moisturizers, lubricants, kana kurapwa kwemishonga chiremba wako anogona kukurudzira

Usambomira kurapwa kwako nemahormone usati wataura nachiremba wako kutanga, kunyangwe mativi emishonga achiita seanodenha. Chikwata chako chekurapa chinowanzo gadzirisa kurapwa kwako kana kuwedzera mishonga yekutsigira kuti ikubatsire kunzwa zviri nani.

Ndeipi nzira yakanakisa yekurapa mahormone?

Kurapa kwakanakisa kwemahormone kunoenderana nekuti wakapfuura here menopause, hunhu hwakananga hwekenza yako, uye hutano hwako hwese. Hapana nzira imwechete yakakodzera munhu wese nekuti mamiriro emunhu wese akasiyana.

Vakadzi vasati vapinda mu menopause vanowanzo budirira nekudziviswa kwemazai pamwe chete nemishonga yakaita se tamoxifen kana aromatase inhibitors. Vakadzi vakapinda mu menopause vanowanzoita zvakanaka ne aromatase inhibitors chete, kunyangwe vamwe vachigona kushandisa tamoxifen.

Oncologist wako anofunga nezvezvinhu zvakaita se nhanho yekenza yako, mamwe mamiriro ehutano, nhoroondo yemhuri, uye zvaunofarira iwe pachako paunenge uchigadzira chirongwa chako chekurapa. Kurapa kwakanakisa ndiko kunobata kenza yako zvakanaka uchichengetedza hupenyu hwako.

Ndezvipi zvinhu zvine njodzi zvekuda kurapwa nemahomoni?

Unogona kuda kurapwa nemahomoni kana kenza yako yemazamu ikawanikwa iine ma hormone receptors, zvisinei nezvimwe zvinhu. Izvi zvinotora anenge 70% yezvose zviitiko zvekenza yemazamu.

Zvimwe zvinhu zvinoita kuti chirongwa chako chekurapa chishande:

• Nhanho yekenza uye saizi payakaonekwa
• Kana kenza yakapararira kumaguru e lymph
• Zera rako uye mamiriro ako e menopause
• Nhoroondo yemhuri yekenza yemazamu kana yezai
• Kushandiswa kwemahomoni ekutsiva kare
• Mamwe mamiriro ehutano akaita se osteoporosis kana chirwere chemoyo

Vakadzi vane kenza ine njodzi yakanyanya vanowanzoenderera mberi nekurapwa nemahomoni kwenguva refu, dzimwe nguva kusvika kumakore gumi. Chiremba wako achagara achiongorora kana kuenderera mberi nekurapa kuchipa zvakawanda zvakanaka kupfuura njodzi.

Zviri nani here kuva nekenza yemazamu ine mahomoni kana isina mahomoni?

Kenza yemazamu ine mahomoni inowanzoita zvakanaka kwenguva refu nekuti inopindura zvakanaka kurapwa nemahomoni. Kuva nezvinhu zvekushandisa zviripo zvinokupa iwe nachiremba wako maturusi akawanda ekurwisa kenza zvakanaka.

Kenza ine mahomoni inowanzo kukura zvishoma nezvishoma kupfuura iyo isina mahomoni, izvo zvinogona kureva nguva yakawanda yekuona nekuzvibata zvakabudirira. Iwo 5-gore mazinga ekupona anowanzoita akakwira kune kenza yemazamu ine mahomoni.

Asi, gomarara risina mahomoni rinowanzoita zviri nani kumishonga yekemikari uye rinogona kubviswa zvachose nemishonga. Mhando dzese dziri mbiri dzinogona kurapwa zvakabudirira kana dzabatwa nekukurumidza, saka tarisa pakutevera chirongwa chako chekurapa chakakurudzirwa nachiremba wako pane kunetseka nezve rudzi rwaunaro.

Ndezvipi zvipingamupinyi zvinogona kuitika zvekurapa mahomoni?

Vanhu vazhinji vanotsungirira kurapa mahomoni zvakanaka, asi semishonga yese, inogona kukonzera mhedzisiro inobva pakureruka kusvika kune yakakomba. Kunzwisisa izvi kunokubatsira kuziva zvekutarisa uye kana uchifanira kubata chiremba wako.

Zvipingamupinyi zvakajairika zvinokanganisa varwere vazhinji zvinosanganisira:

• Kutetepa kwemapfupa (osteoporosis) kunowedzera njodzi yekutyoka
• Kurwadziwa mumajoini uye kuoma, kunyanya mumaoko nemabvi
• Kupisa kwemuviri uye dikita rehusiku
• Kuchinja kwemanzwiro kusanganisira kuora mwoyo kana kushushikana
• Kuwedzera uremu uye shanduko mumuviri
• Kukanganiswa kwehope uye kuneta

Zvisingawanzoitiki asi zvipingamupinyi zvakakomba zvinosanganisira:

• Mavhiri eropa, kunyanya ne tamoxifen
• Njodzi yegomarara reEndometrial nekushandiswa kwenguva refu kwe tamoxifen
• Shanduko yekushanda kwechiropa inoda kuongororwa
• Kurasikirwa kwakanyanya kwemapfupa kunotungamira mukutyoka
• Kushanduka kwemoyo nemimwe mishonga

Chiremba wako anokutarisa zvakanyatso panguva yekurapa kuti abate chero zvipingamupinyi nekukurumidza. Kuongororwa nguva dzose uye bvunzo dzeropa dzinobatsira kuona kuti kurapwa kwako kunoramba kuri kwakachengeteka uye kunoshanda.

Ndinofanira kuona chiremba rini panguva yekurapa mahomoni?

Unofanira kubata chiremba wako nekukurumidza kana ukaona kurwadziwa muchipfuva, kufema kwemhepo, kurwadziwa kwakanyanya kwemakumbo, kana zviratidzo zvemavhiri eropa. Zviratidzo izvi zvinoda kutariswa kwekurapa nekukurumidza uye hazvifaniri kumirira kusvikira musangano wako unotevera.

Ronga musangano mukati memazuva mashoma kana uine kupisa kwakanyanya kunoramba kuripo, kurwadziwa mumajoini kunokanganisa mabasa ezuva nezuva, shanduko dzemanzwiro dzinokunetsa, kana kubuda ropa kwevagina kusinganzwisisike.

Mishonga yekutarisa inowanzoitika mwedzi mitatu kusvika mitanhatu panguva yekurapa. Chiremba wako anodawo kukuona kana uchifunga kumisa mishonga yako kana kana mativi emishonga achikanganisa zvakanyanya hupenyu hwako.

Mibvunzo inowanzo bvunzwa pamusoro pekurapa mahomoni ekenza yemazamu

Mubvunzo 1. Kurapa mahomoni kunoshanda kune ese mhando dzekenza yemazamu here?

Kurapa mahomoni kunoshanda chete kune hormone receptor-positive breast cancers, iyo inomiririra anenge 70% yematambudziko ese ekenza yemazamu. Chirevo chako chepathology chicharatidza kana kenza yako iine estrogen receptors (ER-positive) kana progesterone receptors (PR-positive).

Kana kenza yako iri hormone receptor-negative, kurapwa uku hakuzoshandi nekuti maseru ekenza iwayo haavimbi nemahomoni kuti akure. Chiremba wako achakurudzira mamwe marapirwo senge chemotherapy kana targeted therapies panzvimbo.

Mubvunzo 2. Kurapa mahomoni kunokonzera kuwedzera uremu here?

Vanhu vazhinji vanowana kuwedzera uremu panguva yekurapa mahomoni, kazhinji mapaundi mashanu kusvika gumi panguva yekurapa. Izvi zvinoitika nekuti kurapa kunogona kuderedza metabolism yako uye kuchinja maitiro emuviri wako ekuchengeta mafuta.

Kuwedzera uremu kunowanzoita zvishoma nezvishoma uye kunogoneka nekudya kwakanaka uye kurovedza muviri nguva dzose. Vamwe vanhu vanowana uremu hunogadzikana mushure megore rekutanga rekurapa sezvo muviri wavo uchigadzirisa kumishonga.

Mubvunzo 3. Ndingava nepamuviri ndiri pamishonga yekurapa mahomoni here?

Kurapa mahomoni kunogona kukanganisa kubereka, asi haisi nzira yakavimbika yekudzivirira kubata pamuviri. Kana iwe usati wava kutanga kuenda kumwedzi uye uchishanda pabonde, unofanirwa kushandisa nzira dzekudzivirira kubata pamuviri dzisiri dzemahomoni senge makondomu kana mhangura IUDs.

Kuzvitakura panguva yekurapa mahomoni hakukurudzirwi nekuti zvinogona kukanganisa kurapwa kwako kenza uye zvinogona kukanganisa mwana ari kukura. Kurukurai kuronga mhuri zvakadzama nachiremba wako weoncologist usati watanga kurapwa.

Mubvunzo 4. Ndingade kutora mishonga yekurapa mahomoni kwenguva yakareba sei?

Vanhu vazhinji vanotora mushonga wemahomoni kwemakore 5 kusvika ku10, zvichienderana nemaitiro avo egomarara uye njodzi. Chiremba wako achakurudzira nguva yakakodzera zvichienderana nemamiriro ako chaiwo uye tsvakurudzo yazvino.

Vamwe vanhu vane gomarara rine njodzi yakakwirira vanogona kubatsirwa nenguva refu yekurapa, nepo vamwe vangapedza kurapwa kwavo mumakore 5. Chiremba wako achadzokorora nguva dzose kana kuramba kurapwa kuchipa zvimwe zvikomborero kupfuura njodzi.

Mubvunzo 5. Ndingamira kurapwa nemahomoni here kana mhedzisiro yacho yava kuoma?

Usambomira kurapwa nemahomoni usina kuzvikurukura nechiremba wako weoncologist kutanga, kunyangwe kana mhedzisiro yacho ichiita seyakaoma. Chiremba wako anogona kugadzirisa mushonga wako, kuchinja dose, kana kuwedzera kurapwa kunotsigira kubatsira kubata nemhedzisiro.

Kana usingakwanise zvachose kutsungirira mushonga wako wazvino, chiremba wako anogona kukuchinjira kune imwe sarudzo yekurapa mahomoni. Chinhu chakakosha kushanda pamwechete kuti uwane mhinduro inokuchengeta pakurapa uchichengetedza hupenyu hwako.