Chii chinonzi Stool DNA Test? Chinangwa, Miviri/Maitiro & Mhedzisiro

Stool DNA test chishandiso chakareruka chekuongorora chinotsvaga shanduko dzemajini uye zviratidzo zveropa mumuyenzaniso wako we stool zvinogona kuratidza gomarara remukati kana kukura kusati kwave negomarara. Unogona kuunganidza muyenzaniso kumba uchishandisa kit yakakosha, zvichiita kuti ive imwe nzira iri nyore kune dzimwe nzira dzekuongorora dzinopinda zvakanyanya senge colonoscopy.

Muedzo uyu unoshanda nekutsvaga maitiro eDNA asina kujairika ayo maseru egomarara uye mapolyps makuru anodonhedzera mumatoo ako. Iyo vhezheni yakajairika inonzi Cologuard, iyo inobatanidza DNA kuyedzwa nekuyedzwa kweropa rakavanzika kuti ipe vanachiremba mufananidzo wakajeka wehutano hwemukati mako.

Chii chinonzi stool DNA test?

Stool DNA test inoongorora kufamba kwako kwematumbo kuti uwane zviratidzo zvidiki zvematerial yemajini isingafanirwe kunge iripo. Kana maseru mumukati mako akava negomarara kana kukura kuita mapolyps makuru, anoburitsa DNA isina kujairika uye dzimwe nguva huwandu hudiki hweropa mumugwagwa wako wekugaya.

Muedzo unotora zviratidzo izvi zvekuyambira usati waziva chero zviratidzo. Yakagadzirirwa zvakananga vanhu vari panjodzi yepakati pegomarara remukati, kazhinji avo vane makore 45 zvichikwira vasina nhoroondo yemhuri kana zviratidzo zvemunhu.

Funga nezvazvo semupurisa wemamorekuru anogona kuona matambudziko ari kubika mumukati mako. Muedzo unotsvaga shanduko dzemajini dzakajairika dzinowanikwa mumagomarara emukati, pamwe inotarisa hemoglobin, iyo inoratidza kubuda ropa maziso ako asingakwanise kuona.

Nei stool DNA test ichiitwa?

Chiremba wako anogona kukurudzira muedzo uyu sechikamu chekuongorora gomarara remukati, kunyanya kana usiri kuda kupinda mu colonoscopy. Inoshanda seyakakosha pakati pemiedzo yeropa-mu-stool iri nyore uye maitiro anopinda zvakanyanya.

Chinangwa chikuru ndechokubata gomarara remukati rekuti rikwanise kurapika nekukurumidza, kana kuwana mapolyps makuru asati ava gomarara. Zvidzidzo zvinoratidza kuti kana gomarara remukati rekuti raonekwa nekukurumidza, mwero wekupona kwemakore mashanu unodarika zvikamu makumi mapfumbamwe kubva muzana.

Kutarisa uku kunokosha zvikuru kana uine hanya nekugadzirira colonoscopy, sedation, kana nguva yekuzorora kubasa. Zvinokutendera kuti utore kutarisira kuongororwa kwako kwehutano kubva kunyaradzwa kwemba yako uchiri kuwana mhedzisiro yakavimbika.

Ndeipi nzira yekuedzwa kweDNA yechituru?

Nzira yacho inotanga apo chiremba wako anoraira bvunzo uye kit yekutora inosvika kumba kwako. Iwe uchagamuchira mirairo yakadzama, zvirongo zvekutora, uye zvinhu zvekutumira zvakabhadharwa kuti utumire sampuli yako kulaboratory.

Hezvino zvaunogona kutarisira panguva yekutora:

1. Tora kufamba kwakakwana kwematumbo muchirongo chakapihwa
2. Shandisa probe yakakosha kuunganidza masampuli kubva kunzvimbo dzakasiyana dzechituru
3. Isa sampuli mumhinduro yekuchengetedza inosanganisirwa mukiti
4. Sunga zvese zvinoenderana nemirairo
5. Tumira sampuli kumashure kulabhu mukati menguva yakatarwa

Nzira yose inotora maminitsi mashoma enguva yako. Vanhu vazhinji vanoiwana iri nyore uye isina kunetseka zvakanyanya kupfuura kugadzirira mamwe bvunzo dzekutarisa.

Vashandi velaboratory vachaongorora sampuli yako vachishandisa tekinoroji yepamberi yeDNA sequencing. Mhedzisiro inowanzo svika mukati memavhiki maviri mushure mekunge labhu yagamuchira sampuli yako.

Maitirwo ekugadzirira bvunzo yako yeDNA yechituru?

Kugadzirira bvunzo iyi kuri nyore zvakanyanya kana tichienzanisa nemamwe maitiro ekuongorora colorectal. Haufaniri kutevera kudya kwakakosha, kumisa mishonga, kana kuchinja tsika dzako dzekudya usati watora sampuli yako.

Asi, nguva inokosha kuti uwane mhedzisiro yakarurama. Tora sampuli yako kubva pakufamba kwemukati kunoitika zvakasikwa pane kushandisa laxatives kana enemas, izvo zvinogona kukanganisa kururama kwebvunzo.

Ita shuwa kuti une mudziyo wakachena, wakaoma wekubata sampuli yako yechimbuzi. Vanhu vazhinji vanowana zvichibatsira kuisa plastic wrap pamusoro pechimbuzi kana kushandisa mudziyo unoraswa kuti zviite nyore kuunganidza.

Dzivisa kuunganidza sampuli panguva yekuenda kumwedzi, sezvo ropa kubva kumukana iwoyo rinogona kukanganisa mhedzisiro. Kana uri kusangana nekurutsa kana wanga uchitora maantibiotics nguva pfupi yadarika, kurukurai nguva nachiremba wako.

Ungaverenga sei bvunzo yako yeDNA yechimbuzi?

Mhedzisiro yako yebvunzo yeDNA yechimbuzi inodzoka seyakaita positive kana negative, zvichiita kuti zvinzwisisike zvakanyanya. Mhedzisiro isina kunaka zvinoreva kuti bvunzo haina kuwana mazinga anokosha eDNA isina kujairika kana ropa musampuli yako.

Mhedzisiro yakanaka inoratidza kuti bvunzo yakawana shanduko dzemajini kana ropa rinoda kumwe kuongororwa. Izvi hazvirevi otomatiki kuti une gomarara, asi zvinoreva kuti unoda mamwe bvunzo, kazhinji colonoscopy, kuti uone zviri kukonzera izvi.

Bvunzo iyi ine chiyero chekuona cheanenge 92% yegomarara remukati uye rinenge 69% yemapolyps makuru anogona kuita gomarara. Zvisinei, dzimwe nguva inogona kuburitsa false positives, zvinoreva kuti inoona kusagadzikana kunozoratidza kusina njodzi.

Chiremba wako achatsanangura mhedzisiro yako chaiyo uye achakurukura matanho anotevera zvichienderana nemamiriro ako ega. Vachafungawo nezvezviratidzo zvako, nhoroondo yemhuri, uye hutano hwako hwese pakuongorora mhedzisiro yako.

Ungagadzirisa sei chiyero chako chebvunzo yeDNA yechimbuzi?

Haugone chaizvo

Kana bvunzo yako ikabuda yakanaka, danho rinokosha nderekutevera nemamwe bvunzo dzinokurudzirwa nachiremba wako. Izvi zvinowanzoita kuti uronge colonoscopy kuti utarise zvakananga ura hwako uye uone zviri kukonzera zvinhu zvisina kujairika.

Kuti uve neutano hwakanaka hweura kwenguva refu, funga nzira idzi dzehupenyu dzinogona kubatsira kuderedza njodzi yako:

\n
• Idya zvakawanda zvekudya zvine fiber yakawanda senge michero, miriwo, uye zviyo zvakazara
\n
• Ganhurira kudya kwenyama yakagadzirwa uye nyama tsvuku
\n
• Rovedza muviri nguva dzose kuti urambe uine hutano hwekugaya
\n
• Dzivisa kusvuta uye ganhurira kunwa doro
\n
• Chengeta uremu hune hutano
\n

Maitiro aya anotsigira hutano hwekugaya hwehuwandu uye anogona kubatsira kudzivirira kukura kwepolyps uye gomarara rekolorectal. Zvisinei, havagone kuchinja mhedzisiro yebvunzo yakatogadziriswa.

Ndeipi nhanho yakanakisisa yebvunzo yeDNA yechigaro?

Bvunzo yeDNA yechigaro haipimi mazinga mune tsika yechinyakare, saka hapana nhanho

Zvimwe zvinhu zvinogona kuwedzera mukana wako wekuva nemhedzisiro isina kujairika yebvunzo yeDNA yechigaro. Zera ndicho chinhu chikuru chine njodzi, nekuti mazhinji ekenza yeguru inoitika muvanhu vane makore anopfuura 50, kunyangwe nhungamiro zvino inokurudzira kuongorora kutanga pa45.

Nhoroondo yemhuri yako inotamba basa rakakosha mukati me njodzi yako. Kuva nemubereki, hama, kana mwana ane kenza yeguru kunowedzera mikana yako yekuva nechirwere iwe pachako, zvichikonzera mhedzisiro yebvunzo yakanaka.

Heano zvinhu zvine njodzi zvikuru zvinogona kubatsira kumhedzisiro isina kujairika:

• Nhoroondo yako pachako yezvinhu zvisina kujairika zveguru kana chirwere chinopisa ura
• Zvirwere zvemajini zvakaita seLynch syndrome kana familial adenomatous polyposis
• Kudya kwakanyanya nyama yakagadzirwa uye isina fiber
• Kuputa uye kunwa doro zvakanyanya
• Kufutisa uye mararamiro ekugara
• Type 2 diabetes

Kunzwisisa izvi zvinhu zvine njodzi kunobatsira iwe nachiremba wako kuona nguva dzakakodzera dzekuongorora uye kududzira mhedzisiro mune zvakakodzera. Zvisinei, kenza yeguru inogona kukura muvanhu vasina chero zvinhu zvine njodzi, ndosaka kuongorora nguva dzose kuchiramba kuchikosha kune munhu wese.

Zviri nani kuva nemhedzisiro yakakwira kana yakaderera yebvunzo yeDNA yechigaro here?

Mubvunzo uyu unoratidza kusanzwisisana kwakajairika pamusoro pekuti bvunzo dzeDNA yechigaro dzinoshanda sei. Kusiyana nebvunzo dzeropa dzinoyera mazinga ezvinhu mumuviri wako, bvunzo dzeDNA yechigaro dzinopa mhedzisiro yakanaka kana yakaipa zvichienderana nekuti dzinoona here mamaki akasiyana emajini uye zviratidzo zveropa.

Mhedzisiro yakaipa ndiyo yaunoda kuwana. Izvi zvinoreva kuti bvunzo haina kuwana mazinga anokosha eDNA isina kujairika kana ropa rakavanzika mumuyenzaniso wako, zvichiratidza kuti ura hwako hunoita sehutsika panguva yekuedzwa.

Mhedzisiro yakanaka hairevi kuti "yakakwira" kana "yakaderera" asi inoratidza kuti bvunzo yakaona shanduko dzemajini kana ropa rinoda kumwe kuferefetwa. Bvunzo haina kupa chiyero kana nhanho inogona kuenzaniswa neyakajairika.

Funga nezvazvo semuchina wekuona utsi mumba mako. Hauyere mazinga akasiyana eutsi, unongokuzivisa chete kana paine utsi hwakawanda hunoda kutariswa. Saizvozvowo, bvunzo yeropa remudumbu inozivisa chiremba wako kana paine zvinhu zvakawanda zvinonetsa zvekukurudzira kumwe kuyedzwa.

Ndezvipi zvingaitika kana bvunzo yeropa remudumbu isina kujairika?

Mhedzisiro yebvunzo yeropa remudumbu isina kujairika pachayo haina kukonzera matambudziko emuviri, asi inogona kukonzera kushushikana kwemoyo nekuzvidya mwoyo iwe uchimirira kumwe kuyedzwa. Vanhu vazhinji vanonetseka nekukasira nezvekuva nekenza, kunyangwe mhedzisiro yakanaka kazhinji iine tsananguro dzisina njodzi.

Kunetseka kukuru nemhedzisiro yakanaka ndezvazvingaratidza pane mhedzisiro yebvunzo pachayo. Kana bvunzo yakaona kenza yemudumbu yakatanga kana mapolyps makuru, mamiriro ezvinhu anoda kurapwa nekukurumidza kudzivirira kufambira mberi.

Zvisinei, mhedzisiro yenhema inogona kutungamirira kukuzvidya mwoyo kusingadiwi uye kumwe kuyedzwa. Zvidzidzo zvinoratidza kuti anenge 13% ekuongororwa kweropa remudumbu anobuda semhedzisiro yenhema, zvinoreva kuti colonoscopy inotevera hairatidzi kenza kana mapolyps akakosha.

Matambudziko asingawanzoitiki anogona kubuda kubva mumaitiro ekutevera pane bvunzo yemudumbu pachayo. Kana mhedzisiro yako yakanaka ikakonzera colonoscopy, maitiro iwayo anotakura njodzi diki dzekubuda ropa, kuboora, kana kuita zvisina kunaka kumishonga yekuzorodza, kunyangwe matambudziko akakomba anoitika mune vashoma vanopfuura 1 mune 1,000 kesi.

Ndezvipi zvingaitika kana bvunzo yeropa remudumbu isina kunaka?

Mhedzisiro yakaipa yebvunzo yeDNA yematumbo inowanzoita kuti munhu anzwe kugadzikana, asi zvakakosha kunzwisisa kuti hapana bvunzo yekutarisa yakakwana 100%. Kunetseka kukuru nemhedzisiro yakaipa ndiko kukwanisa kwezvakaipa zvenhema, uko bvunzo inokundikana kuona kenza iripo kana mapolyps.

Zvidzidzo zvinoratidza kuti bvunzo dzeDNA yematumbo dzinogona kukundikana kuona anenge 8% ekenza yematumbo uye anenge 31% emapolyps makuru. Izvi zvinoreva kuti vamwe vanhu vane mhedzisiro yakaipa vangave vachiri nemamiriro ezvinhu anoda kutariswa.

Njodzi yezvakaipa zvenhema inowanzoita yakakwira kune mapolyps madiki uye kenza yematanho ekutanga. Mamiriro aya angasaburitsa DNA isina kujairika kana ropa rakakwana kuti riite mhedzisiro yakanaka, zvichikwanisa kunonotsa kuongororwa.

Imwe nyaya inogona kuitika ndeyekuti mhedzisiro yakaipa inogona kupa vamwe vanhu pfungwa yenhema yekuchengeteka, zvichivatungamirira kuti varegeredze zviratidzo kana kusvetuka misangano yekutarisa yemberi. Kunyangwe nebvunzo yakaipa, iwe unofanirwa kuchine kubata chiremba wako kana iwe ukaita zviratidzo zvinonetsa zvakaita sekuchinja kwenguva refu mumaitiro ematumbo, ropa mumatope, kana kurasikirwa uremu kusingatsanangurike.

Ndingatarisana nechiremba rini nekuda kwebvunzo yeDNA yematumbo?

Unofanira kubata chiremba wako nekukasira kana ukagamuchira mhedzisiro yakanaka yebvunzo yeDNA yematumbo. Vachakubatsira kunzwisisa zvinorehwa nemhedzisiro uye kuronga bvunzo dzakakodzera dzekutevera, kazhinji colonoscopy, kuti uone chikonzero chezvakawanikwa zvisina kujairika.

Usamirira kana kuedza kududzira mhedzisiro wega. Nguva inogona kukosha kana bvunzo yakawana kenza yekutanga kana mapolyps makuru, uye kutevera nekukurumidza kunokupa mukana wakanaka wekurapa kubudirira kana zvichidikanwa.

Kunyangwe nemhedzisiro yakaipa, unofanirwa kuona chiremba wako kana ukaita chero zviratidzo zvinonetsa. Zviratidzo izvi zvinoda kutariswa kwekurapa nekukasira zvisinei nemhedzisiro yako yebvunzo ichangoburwa:

• Ropa mumatsvina yako kana matsvina matema, ane tar
• Kuchinja kunoramba kuripo mumaitiro emudumbu kunotora mavhiki anopfuura mashoma
• Kurasikirwa uremu kusingatsanangurwi
• Kurwadziwa mudumbu kunoramba kuripo kana kupeta
• Kunzwa sekunge haugone kubvisa matumbu ako zvachose

Uyezve, rongedza nguva dzose dzekutarisa kuti ukurukure chirongwa chako chekuongorora chiri kuenderera mberi. Chiremba wako achabatsira kuona kuti unoda riini bvunzo yako inotevera yeDNA yematsvina kana kuti dzimwe nzira dzekuongorora dzingave dzakakodzera zvakanyanya zvichienderana nezvinhu zvako zverisiko.

Mibvunzo inowanzo bvunzwa nezve bvunzo yeDNA yematsvina

Mubvunzo 1: Bvunzo yeDNA yematsvina yakanaka pakuona gomarara remukati here?

Hongu, bvunzo dzeDNA yematsvina dzishandiso dzinoshanda pakuona gomarara remukati, nekudzidza kunoratidza kuti vanobata anenge 92% yegomarara riripo. Izvi zvinoita kuti vave vanonyanya kunzwisisa kupfuura bvunzo dzekare dzematsvina dzaingotarisa ropa.

Bvunzo iyi inonyanya kunaka pakuwana gomarara rakakura, rakaoma iro rinoburitsa DNA yakawanda isina kujairika mumatsvina. Zvisinei, haina kushanda zvishoma pakuona mapolyps maduku uye gomarara rematanho ekutanga zvichienzaniswa necolonoscopy.

Kune vanhu vari panjodzi yepakati avo vanosarudza kuongorora kusina kupinda, bvunzo yeDNA yematsvina inopa chiyero chakanaka chekururama uye nyore. Zvinokosha zvikuru kune avo vangadzivisa kuongororwa zvachose nekuda kwekufunganya nezve colonoscopy.

Mubvunzo 2: Mhedzisiro yepamusoro yebvunzo yeDNA yematsvina inokonzera gomarara here?

Kwete, mhedzisiro yebvunzo yeDNA yematsvina haina kukonzera gomarara. Bvunzo iyi inongowana shanduko dzemajini uye zviratidzo zveropa zvingaratidza kuti gomarara kana mamiriro ekutanga-gomarara aripo kare mumukati mako.

Funga nezve bvunzo iyi semutumwa anoshuma zvaanowana, kwete sechinhu chinogadzira dambudziko. Kana bvunzo yako iri yakanaka, zvinoreva kuti bvunzo yakawana shanduko dzinokosha dzinoda kumwe kuongororwa kuti dzizive chikonzero chavo.

Mamiriro akakonzera mhedzisiro yakanaka, sekunge mapolyps kana kenza, akakura ega pasina chokuita nebvunzo. Kuonekwa kwekutanga kuburikidza nekuedzwa kunovandudza mikana yako yekubudirira kurapwa kana mamiriro akakomba akawanikwa.

Q3: Ndingadzokorora sei bvunzo yeDNA yechigaro kakawanda?

Mirairo yezvokurapa inokurudzira kudzokorora bvunzo dzeDNA yechigaro makore matatu oga oga kana mhedzisiro yako isina kunaka uye iwe uchiramba uri panjodzi yepakati pekukura kenza yemukati. Iyi nguva inogadzirisa kuongorora kunobudirira nekufunga kunoshanda.

Nguva yemakore matatu yakavakirwa patsva tsvakurudzo inoratidza kuti kenza dzemukati dzinokura nekukurumidza sei uye kuti zvinotora nguva yakareba sei kuti mapolyps ave kenza. Iyi purogiramu inobatsira kubata matambudziko nekukurumidza uchidzivirira kuongorora kusingakoshi.

Zvisinei, chiremba wako angakurudzira nguva yakasiyana zvichienderana nezvinhu zvako zvaunotarisira, nhoroondo yemhuri, kana iwe ukaita zviratidzo pakati pebvunzo dzakarongwa. Nguva dzose tevera mazano chaiwo echiremba wako ezvinhu zvako.

Q4: Mishonga inogona kukanganisa mhedzisiro yebvunzo yeDNA yechigaro here?

Mishonga yakawanda haikanganisi zvakanyanya mhedzisiro yebvunzo yeDNA yechigaro, icho chimwe chakanakira nzira iyi yekutarisa. Iwe haufanire kumisa kutora mishonga yako yenguva dzose usati watora sampuli yako.

Zvisinei, kushandiswa kwemishonga inorwisa mabhakitiriya munguva pfupi yapfuura kunogona kukanganisa kururama kwebvunzo nekuchinja nharaunda yemabhakitiriya mumukati mako. Kana iwe wakatora mishonga inorwisa mabhakitiriya mumavhiki mashoma apfuura, kurukurai nguva nachiremba wako.

Mishonga inotapudza ropa yakaita seaspirin kana warfarin haikanganisi chikamu cheDNA chebvunzo, asi inogona kuwedzera mikana yekuwana ropa muchigaro chako. Chiremba wako anogona kubatsira kududzira mhedzisiro maererano nemishonga yako.

Q5: Bvunzo yeDNA yechigaro iri nani pane colonoscopy here?

Miedzo yeDNA mumashure nemacoscopy imwe neimwe ine zvainobatsira, zvichiita kuti zvive zvakakodzera kune mamiriro akasiyana pane imwe iri nani zvachose. Colonoscopy inoramba iri iyo goridhe standard yekutsvaga kenza yemukati nekuti inogona kuona nekubvisa polyps mune imwechete nzira.

Chinhu chikuru chinobatsira chekuedzwa kweDNA mumashure ndiko kuita nyore uye kunyaradza. Unogona kuunganidza sampuli kumba pasina kugadzirira, nguva yekubva kubasa, kana sedation. Izvi zvinoita kuti ive sarudzo yakanaka kune vanhu vangadzivise kuongororwa.

Zvisinei, colonoscopy yakanyatsoongororwa, ichibata anenge 95% ye polyps hombe ichienzaniswa ne69% yemiedzo yeDNA mumashure. Kana uri panjodzi yakakwirira kana uine zviratidzo zvinonetsa, chiremba wako anogona kukurudzira colonoscopy kuti uwane ongororo yakazara.