Chii chinonzi Deutetrabenazine: Zvinoshandiswa, Dosage, Migumisiro uye Zvimwe

Deutetrabenazine mushonga unopiwa nachiremba unobatsira kudzora kufamba kusingadiwi muvanhu vane mamwe mamiriro ekuona tsinga. Inoshanda nekuderedza zvinyoro nyoro basa remakemikari ehuropi anogona kukonzera kufamba kwemhasuru kusingadiwi, ichipa tariro uye kuvandudzwa kwemhando yehupenyu kune avo vanobata nezvirwere zvekufamba.

Chii chinonzi Deutetrabenazine?

Deutetrabenazine ndeyeboka remishonga inonzi VMAT2 inhibitors. Funga nezvayo semabhureki emabhureki echinyoro chekudzora kufamba kwehuropi hwako. Mushonga unobatsira kudzora dopamine, kemikari yehuropi inotamba basa rakakosha mukudzora kufamba kwemhasuru.

Mushonga uyu wakagadzirirwa kuve wakareba uye kukonzera mashoma mativi emigumisiro kupfuura mishonga yekare yakafanana. Inotorwa nemuromo semapiritsi uye inoda kunyatso tariswa nachiremba wako kuti awane chiyero chakakodzera zvaunoda.

Deutetrabenazine Inoshandiswa Kunei?

Deutetrabenazine inonyanya kunyorerwa mamiriro maviri makuru anokonzera kufamba kusingadiwi. Chiremba wako anogona kukurudzira mushonga uyu kana uri kubata ne chorea ine hukama nechirwere cheHuntington kana tardive dyskinesia.

Huntington's disease chorea inosanganisira kufamba-famba, kusina kutaurwa kunogona kukanganisa maoko ako, makumbo, chiso, uye hunde. Kufamba uku kazhinji kunowedzera kuoneka kana wakaneta kana kuyedza kuisa pfungwa. Deutetrabenazine inogona kubatsira kuderedza kuoma kwekufamba uku, zvichiita kuti mabasa ezuva nezuva ave nyore kubata nawo.

Tardive dyskinesia inowanzoitika mushure mekushandisa kwenguva refu mamwe mishonga yepfungwa. Mamiriro aya anokonzera kudzokorora, kufamba kusingadiwi, kazhinji kuchikanganisa chiso, rurimi, uye shaya. Unogona kuona kunanzva miromo, kubuda rurimi, kana kugunun'una kwechiso chausingakwanise kudzora.

Deutetrabenazine Inoshanda Sei?

Deutetrabenazine inoshanda nekudzivisa protein inonzi VMAT2 muuropi mako. Protein iyi ndiyo inotakura dopamine munzvimbo dzekuchengetera mukati memaseru etsinga. Nekuderedza mabasa e dopamine munzvimbo dzakasiyana dzeuropi, mushonga uyu unobatsira kudzikamisa zviratidzo zvekufamba zvakanyanya.

Uyu unoonekwa semushonga une simba repakati nepakati rinoda kugadziriswa kwemadosi zvishoma nezvishoma. Chiremba wako achakutangisa nemadosi mashoma uye achiwedzera zvishoma nezvishoma kwemavhiki akati wandei. Iyi nzira yekuchenjerera inobatsira muviri wako kuti ujairane uye inoderedza mhedzisiro inogona kuitika.

Mushonga hauporesi chirwere chiri pasi asi unopa rubatsiro rwakakura rwezviratidzo. Vanhu vazhinji vanoona kuvandudzwa mukudzora kwavo kufamba mukati memavhiki mashoma ekutanga kurapwa, kunyangwe kubatsirwa kwakazara kungatora mwedzi yakati wandei kuti ikure.

Ndingatora sei Deutetrabenazine?

Tora deutetrabenazine sezvakanyorwa nachiremba wako, kazhinji kaviri pazuva nechikafu. Kuitora nezvokudya kunobatsira muviri wako kutora mushonga zviri nani uye kunoderedza mukana wekuti dumbu rigumbuke. Unogona kuitora nechero rudzi rwechikafu, asi kuenderana nenguva kunobatsira kuchengetedza mazinga akagadzikana mumuviri wako.

Medza mahwendefa ese nemvura yakawanda. Usapwanya, kutsenga, kana kuputsa mahwendefa, sezvo izvi zvinogona kukanganisa nzira iyo mushonga unoburitswa mumuviri wako. Kana uine dambudziko rekumedza mapiritsi, taura nemu pharmacist wako nezveimwe nzira.

Chiremba wako achakutangisa nemadosi mashoma uye achiwedzera zvishoma nezvishoma vhiki rega rega kana maviri. Kuwedzera uku zvishoma nezvishoma kunobatsira muviri wako kuti ujairane uye kunobvumira timu yako yehutano kuti iongorore chero mhedzisiro. Usambofa wakagadzirisa dosi yako wega, kunyangwe ukafunga kuti mushonga haushandi sezvawaida.

Ndingatora Deutetrabenazine kwenguva yakareba sei?

Deutetrabenazine inowanzoita mushonga wenguva refu waungada kutora kwemwedzi kana makore. Kureba kwenguva kunoenderana nemamiriro ako chaiwo uye kuti unopindura sei kumushonga. Chiremba wako achagara achiongorora kana mabhenefiti achienderera mberi achikunda chero njodzi dzinogona kuitika.

Kune chirwere cheHuntington, unogona kuda kutora mushonga uyu kwemakore mazhinji sezvo mamiriro acho achienderera mberi. Chiremba wako achagadzirisa mushonga wako nekufamba kwenguva zvichienderana nezviratidzo zvako uye hutano hwako hwese. Kuongororwa nguva dzose kunobatsira kuona kuti mushonga unoramba uchishanda uye wakachengeteka kwauri.

Kana uine tardive dyskinesia, nguva yako yekurapa inogona kusiyana. Vamwe vanhu vanoona kuvandudzwa kwezviratidzo zvavo nekufamba kwenguva uye vanogona kukwanisa kuderedza mushonga wavo kana kumisa mushonga pasi pekutariswa kwechiremba. Usambomira kutora deutetrabenazine kamwe kamwe, sezvo izvi zvinogona kukonzera kuti zviratidzo zvako zvidzokere kana kuwedzera.

Ndezvipi Zvakaipa ZveDeutetrabenazine?

Semishonga yese, deutetrabenazine inogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachizvitsungirira zvakanaka. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakagadzirira uye uzive kuti ungataurirana riini nemupi wako wehutano.

Mhedzisiro yakajairika inowanzoita nyoro uye inowanzoita nani sezvo muviri wako uchigadzirisa kumushonga:

• Kuzara kana kuneta
• Dhiarrhea kana kusvotwa
• Muromo wakaoma
• Kutambudzika kurara
• Kuzvidya mwoyo kana kusagadzikana

Izvi zvinowanzoitika mhedzisiro zvinowanzoita zvishoma zvinonetsa mushure memavhiki mashoma ekurapa. Kugara uine mvura yakakwana, kudya chikafu chinogara chiripo, uye kuchengetedza tsika dzakanaka dzekurara zvinogona kubatsira kuderedza mhedzisiro iyi.

Vamwe vanhu vanogona kusangana nemhedzisiro inonyanya kukosha iyo inoda kutariswa kwechiremba nekukasira. Izvi zvinosanganisira zviratidzo zvekuora mwoyo, pfungwa dzekuzvikuvadza, kuneta kwakanyanya kunokanganisa mabasa ezuva nezuva, kana matambudziko matsva ekufamba senge kuoma kwemhasuru kana kudengenyeka.

Kazhinji, deutetrabenazine inogona kukonzera mamiriro akakomba anonzi neuroleptic malignant syndrome. Izvi zvinosanganisira fivha yakanyanya, kuoma kwemhasuru, kuvhiringidzika, uye shanduko mumoyo kana ropa. Kunyange zvazvo zvisingawanzoitiki, izvi zvinoda rubatsiro rwekurapa rwechimbichimbi kana zvaitika.

Ndiani Asingafaniri Kutora Deutetrabenazine?

Vanhu vakati wandei vanofanira kudzivisa deutetrabenazine nekuda kwekuwedzera njodzi yematambudziko akakomba. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa asati akuraira mushonga uyu kuti ave nechokwadi chekuti wakachengeteka kwauri.

Haufaniri kutora deutetrabenazine kana uine matambudziko akakomba echiropa, sezvo muviri wako ungasaite kugadzirisa mushonga zvakanaka. Vanhu vane nhoroondo yekushushikana kana pfungwa dzekuzviuraya vanoda kufungwa zvakakosha, sezvo mushonga unogona kuwedzera mamiriro aya mune vamwe vanhu.

Kana uri kutora mishonga yakati wandei, deutetrabenazine ingasava yakakodzera kwauri. Izvi zvinosanganisira MAO inhibitors, mamwe maantidepressants, uye mishonga inogona kukonzera kusagadzikana kwemoyo. Murapi wako wemishonga uye chiremba vachaongorora mishonga yako yese iripo kuti vaone kana paine kusangana kunogona kuitika.

Vakadzi vane pamuviri kana vanoyamwisa vanofanira kukurukura njodzi nemabhenefiti zvakanyatsonaka nemupi wavo wehutano. Kunyange zvazvo mushonga usina kunyatsodzidzwa panguva yekuzvitakura, chiremba wako angakuraira kana mabhenefiti achipfuura njodzi dzinogona kuitika kwauri nemwana wako.

Mazita eDeutetrabenazine Brand

Deutetrabenazine inowanikwa pasi pezita rekuti Austedo muUnited States. Iyi ndiyo fomu inonyanya kurairwa yemushonga uye inouya mumasimba akati wandei etableti kuti ibvumire kuyera kwakaringana.

Dzimwe nyika dzinogona kunge dziine mazita akasiyana emhando kana shanduro dzakajairika dziripo. Nguva dzose tarisa nemurapi wako wemishonga kuti uve nechokwadi chekuti uri kugamuchira mushonga wakarurama, kunyanya kana uchifamba kana kuenda kune imwe nzvimbo.

Deutetrabenazine Alternatives

Kana deutetrabenazine isina kukodzera iwe, mishonga yakati wandei inogona kukubatsira kudzora zviratidzo zvechirwere chako chekufamba. Chiremba wako achatarisa mamiriro ako chaiwo, nhoroondo yako yezvokurapa, uye zvinangwa zvekurapa paanenge achiongorora dzimwe sarudzo.

Pachirwere cheHuntington's chorea, tetrabenazine imushonga wekare unoshanda zvakafanana asi unogona kukonzera migumisiro yakawanda. Vamwe vanhu vanobatsirwawo nemishonga yeantipsychotic yakaita sehaloperidol kana risperidone, kunyangwe izvi zvine njodzi dzavo nemabhenefiti.

Tardive dyskinesia inogonawo kurapwa nevalbenazine, imwe VMAT2 inhibitor yakafanana ne deutetrabenazine. Vamwe vanhu vanowana kubudirira nemavitamini E supplements kana kuchinja kune dzimwe mishonga yepfungwa isingakonzere matambudziko ekufamba.

Nzira dzisiri dzemishonga dzakaita sephysical therapy, occupational therapy, uye speech therapy dzinogona kuwedzera chero kurapwa kwemishonga. Aya marapirwo anokubatsira kuvandudza nzira dzekudzora zviratidzo uye kuchengetedza kuzvimirira kwako muzviitiko zvemazuva ese.

Ko Deutetrabenazine Zviri Nani Kupfuura Tetrabenazine?

Deutetrabenazine inopa zvakanakira zvakati wandei pamusoro pe tetrabenazine, kunyangwe mishonga yese iri miviri ichishanda nenzira imwechete. Musiyano mukuru uri mukuti unofanirwa kuzvitora kakawanda sei uye maprofiles avo emigumisiro.

Deutetrabenazine inowanzoita kuti utore kaviri pazuva, nepo tetrabenazine ichiwanzoda kutora katatu pazuva. Iyi purogiramu iri nyore inogona kuita kuti zvive nyore kuyeuka mushonga wako uye kuchengetedza mazinga akagadzikana mumuviri wako zuva rese.

Vanhu vazhinji vanowana migumisiro mishoma ne deutetrabenazine, kunyanya kusanyanya kurara uye kuora mwoyo. Mushonga uyu haukwanisiwo kukonzera kudonha kukuru kweropa kana wamuka nekukurumidza. Zvisinei, mhinduro dzemunhu mumwe nemumwe dzinosiyana, uye vamwe vanhu vanogona kuramba vachifara pa tetrabenazine.

Chiremba wako achafunga nezve zviratidzo zvako zvakajeka, mararamiro, uye nhoroondo yako yezvokurapa paanenge achisarudza pakati pemishonga iyi. Sarudzo "yakanaka" inoenderana zvachose nekuti mushonga wega wega unoshanda sei kune mamiriro ako akasiyana uye kuti ndedzipi mhedzisiro yaunogona kutsungirira zvakanaka.

Mibvunzo Inowanzo Bvunzwa Pamusoro peDeutetrabenazine

Deutetrabenazine Yakachengeteka Here Kune Zvirwere Zvemoyo?

Deutetrabenazine inogona kushandiswa zvakachengeteka muvanhu vazhinji vane chirwere chemoyo, asi inoda kunyatso tariswa. Mushonga unogona dzimwe nguva kukanganisa rhythm yemoyo, saka chiremba wako anogona kutarisa kushanda kwemoyo wako usati watanga kurapwa uye nguva nenguva panguva yekurapa.

Kana uine nhoroondo yekurova kwemoyo kusina kujairika kana kutora mishonga yezvirwere zvepfungwa, chiremba wako anogona kuraira electrocardiogram (EKG) kuti atarise basa remagetsi remoyo wako. Izvi zvinobatsira kuona kuti mushonga hauzokanganisi zvakaipa nemamiriro ako emoyo kana mimwe mishonga yemoyo.

Ndoita Sei Kana Ndikatora Deutetrabenazine Yakawanda Netsaona?

Kana netsaona ukatora deutetrabenazine yakawanda kupfuura yakarairwa, taura nachiremba wako kana nzvimbo yekudzora muchetura nekukasira. Kutora zvakanyanya kunogona kukonzera kurara zvakanyanya, kuvhiringidzika, kuoma kwemhasuru, kana matambudziko ekufema anoda kutariswa kwekurapa.

Usaedze kuzviita kurutsa kana kutora mimwe mishonga yekurwisa overdose. Pane kudaro, tsvaga rubatsiro rwekurapa nekukasira, kunyanya kana ukanzwa kurara zvakanyanya, uine matambudziko ekufema, kana uine kuoma kwemhasuru. Uya nebhodhoro remishonga yako kuti ubatsire vanopa hutano kunzwisisa chaizvo zvawakatora uye zvakawanda sei.

Ndoita Sei Kana Ndikakanganwa Dose yeDeutetrabenazine?

Kana ukakanganwa dose, itore paunorangarira, kunze kwekunge yava pedyo nedose yako inotevera yakarongwa. Kana zvapfuura maawa matanhatu kubva padosi yako yakakanganwa uye uri mukati memaawa mashoma edosi yako inotevera, skip the missed dose and continue with your regular schedule.

Usambofa wakatora zvikamu zviviri panguva imwe chete kuti ugadzirise chikamu chawakakanganwa, sezvo izvi zvinogona kuwedzera njodzi yako yezvinhu zvisingadiwi. Kana iwe uchikanganwa zvikamu kakawanda, funga nezvekuisa maalarm pafoni yako kana kushandisa chirongwa chemishonga kuti zvikubatsire kuyeuka nguva yako yemishonga.

Ndingamira Rini Kutora Deutetrabenazine?

Usambofa wakamira kutora deutetrabenazine kamwe kamwe usati wataura nachiremba wako kutanga. Kumira kamwe kamwe kunogona kukonzera zviratidzo zvako zvekufamba kudzoka nekukurumidza uye zvinogona kuva zvakanyanya kupfuura usati watanga kurapwa.

Chiremba wako achakubatsira kuderedza zvishoma nezvishoma chikamu chako kwemavhiki akati wandei kana uchida kumisa mushonga. Iyi nzira yekuderedza zvishoma nezvishoma inobvumira muviri wako kuti ugadzirise uye inobatsira kudzivirira zviratidzo zvekusiya kana kudzoka kamwe kamwe kwezviratidzo zvako zvekufamba.

Ndinganwa Doro Ndiri Kutora Deutetrabenazine?

Zvakanaka kudzivisa doro uchitora deutetrabenazine, sezvo zvinhu zvese zviri zviviri zvinogona kukonzera kurara uye kukanganisa kubatana kwako. Kuzvibatanidza kunogona kuwedzera njodzi yako yekuwa, tsaona, uye kunyanyisa kuneta izvo zvinogona kuva njodzi.

Kana ukasarudza kunwa dzimwe nguva, zvidzore iwe pachako kumari shoma uye teerera zvakanyanya kuti unonzwa sei. Usambofa wakatyaira kana kushandisa michina mushure mekunwa uchitora mushonga uyu, uye gara uchikurukura kushandiswa kwako doro nechiremba wako wehutano kuitira kuti vakwanise kukutarisa zvakakodzera.