Chii chinonzi Dextromethorphan uye Quinidine: Zvinoshandiswa, Madosi, Migumisiro Yemuviri uye Zvimwe

Dextromethorphan uye quinidine mushonga unopiwa nachiremba unosanganisa zvinoshanda zviviri kurapa mamiriro chaiwo ekuongorora neurological anonzi pseudobulbar affect (PBA). Musanganiswa uyu unoshanda zvakasiyana pane mushonga wega wega, uchigadzira nzira yekurapa yakasiyana yevanhu vanoita zviitiko zvekuseka kana kuchema zvisingaenderane nemanzwiro avanoita mukati.

Kana iwe kana mumwe munhu waunoda akanyorerwa mushonga uyu, unogona kunge uri kubata nemamiriro anogona kunzwa achikunda uye achinyadzisa. Kunzwisisa kuti kurapwa uku kunoshanda sei kunogona kukubatsira kuti unzwe wakavimbika nezve chirongwa chako chekutarisira uye zvaunotarisira kuenda mberi.

Chii chinonzi Dextromethorphan uye Quinidine?

Dextromethorphan uye quinidine mushonga unopiwa nachiremba unosanganisa zvinodhaka zviviri zvakasiyana mukati mekapsule imwe. Zita remhando yemusanganiswa uyu ndiNuedexta, uye yakagadzirirwa kurapa pseudobulbar affect (PBA).

Dextromethorphan ikomponi yaungaziva kubva kumishonga yekukosora inotengeswa pasina mushonga, asi mumusanganiswa uyu, inoshanda neimwe nzira yakasiyana zvachose. Quinidine mushonga wemoyo wakashandiswa kwemakumi emakore kurapa kusagadzikana kwemoyo. Kana mishonga miviri iyi yasanganiswa mumadosi chaiwo, inoshanda pamwe chete kubatsira kudzora nzira dzehuropi dzakabatanidzwa mukutaura kwemanzwiro.

Musanganiswa uyu wakasiyana nekuti quinidine inobatsira dextromethorphan kuti igare ichishanda mumuviri wako kwenguva refu. Pasina quinidine, dextromethorphan yaizoputsika nekukurumidza nechiropa chako kuti isashande kurapa PBA.

Chii chinonzi Dextromethorphan uye Quinidine chinoshandiswa?

Mishonga iyi yakabvumidzwa zvakananga kurapa pseudobulbar affect (PBA), chirwere chetsinga chinokonzera zviitiko zvisingatarisirwi, zvisingadzoreki zvekunyemwerera kana kuchema. Zviitiko izvi zvinoitika pasina yambiro uye kazhinji hazvienderani nemanzwiro ako chaiwo.

PBA inowanzoitika muvanhu vane mamwe mamiriro etsinga kana kukuvara kwehuropi. Unogona kusangana nePBA kana uine amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), chirwere cheAlzheimer, chirwere cheParkinson, kana kana wakambova nesitroko kana kukuvara kwehuropi.

Zviitiko zvinogona kunzwa zvichinyadzisa uye zvinoshungurudza nekuti zvinoita sezvinobuda pasina kwaunobva. Unogona kuzviwana uchichema zvisingadzoreki panguva yenguva inofadza, kana kunyemwerera zvisina kufanira panguva yekukurukurirana kwakakomba. Maitiro aya anogona kukanganisa hukama uye kuita kuti mamiriro emagariro anzwe asina kugadzikana.

Zvakakosha kunzwisisa kuti PBA yakasiyana nekushushikana kana matambudziko emanzwiro. Kubuda kwemanzwiro hakuratidzi manzwiro ako chaiwo, uye zvinokonzerwa nekukuvadzwa kwenzira dzehuropi dzinowanzoita kuti manzwiro aenzane.

Dextromethorphan neQuinidine Zvinoshanda Sei?

Mishonga iyi inoshanda nekunangana nenzira dzehuropi dzinodzora kuratidzwa kwemanzwiro. Musanganiswa uyu unoonekwa semushonga wakasimba zvishoma uyo unogona kuderedza zvakanyanya zviitiko zvePBA kana uchishandiswa nguva dzose.

Dextromethorphan inokanganisa mamwe makemikari ehuropi anonzi neurotransmitters, kunyanya ayo anobatanidzwa mumaseketi ehuropi anodzora kuchema nekunyemwerera. Inobatsira kugadzirisa nzira idzi kuitira kuti dzisapfure zvisina kufanira.

Quinidine inotamba basa rekutsigira nekudzivisa enzyme muchiropa chako chinowanzo putsa dextromethorphan nekukurumidza. Izvi zvinobvumira dextromethorphan kuti igare ichishanda muhurongwa hwako kwenguva yakareba kuti ive inobatsira kurapa PBA.

Mushonga hauporesi chirwere chetsinga chinokonzera PBA yako, asi unogona kuderedza zvakanyanya kuwanda uye simba rekuseka kana kuchema zvisingadzoreki. Vanhu vazhinji vanoona kuvandudzwa mukati memavhiki mashoma ekutanga ekurapa.

Ndingatora sei Dextromethorphan uye Quinidine?

Unofanira kutora mushonga uyu sezvinorayirwa nachiremba wako, kazhinji kaviri pazuva uine kana pasina chikafu. Madosi ekutanga anowanzoita kamwe chete capsule mumaawa gumi nemaviri oga oga, asi chiremba wako anogona kuchinja izvi zvichienderana nekuti unopindura sei kurapwa.

Unogona kutora macapsules nemvura, mukaka, kana muto. Hapana chinodiwa chakakosha chekutora izvi nechikafu, asi kana uine dumbu rinovava, kuzvitora nechikafu chakareruka kana snack zvinogona kubatsira.

Edza kutora madosi ako panguva imwe chete zuva rega rega kuti uchengetedze mazinga akagadzikana emushonga mumuviri wako. Kugadzira zviyeuchidzo zvefoni kana kushandisa chirongwa chemapiritsi kunogona kukubatsira kuti urambe uchienderana nehurongwa hwako hwekurapa.

Usapwanye, kutsenga, kana kuvhura macapsules. Akagadzirirwa kuburitsa mushonga nenzira yakatarwa, uye kuchinja capsule kunogona kukanganisa kuti kurapwa kunoshanda sei kana kuwedzera njodzi yako yemigumisiro.

Ndingatora kwenguva yakareba sei Dextromethorphan uye Quinidine?

Kureba kwekurapa kunosiyana zvichienderana nemamiriro ako ega uye kuti unopindura sei mushonga. Vanhu vazhinji vanofanira kuzvitora kwenguva refu kuti vachengetedze kutonga kwezviratidzo zvavo zvePBA.

Chiremba wako anogona kuda kukuona nguva dzose mumwedzi mishoma yekutanga yekurapa kuti aone kuti mushonga uri kushanda sei uye kutarisa chero migumisiro. Vanogona kuchinja dosi yako kana nguva zvichienderana nekupindura kwako.

Vamwe vanhu vanoona kuvandudzwa muzviitiko zvavo zvePBA mukati memavhiki mashoma ekutanga, nepo vamwe vachigona kuda mwedzi yakati wandei kuti vawane zvizere. Chinhu chakakosha ndechokushivirira uye kuenderana nekutora mushonga sezvakanyorwa.

Usamira kutora mushonga uyu kamwe kamwe usina kutanga wataura nachiremba wako. Vanogona kuda kuderedza zvishoma nezvishoma mushonga wako kudzivirira chero zvingaitika zvekusiya mushonga kana kudzoka kwezviratidzo zvePBA.

Ndezvipi Zvazvinoitika Zvakaipa zveDextromethorphan neQuinidine?

Semishonga yese, dextromethorphan nequinidine zvinogona kukonzera zvazvinoitika zvisina kunaka, kunyangwe kwete munhu wese anozviwana. Kunzwisisa zvekutarisira kunogona kukubatsira kuti unzwe wakagadzirira uye kuziva kana uchifanira kutaurirana nemupi wehutano hwako.

Zvakaitika zvisina kunaka zvakajairika zvinowanzoita zvinyoro uye zvinowanzoita zviri nani sezvo muviri wako uchigadzirisa kumushonga mumavhiki mashoma ekutanga ekurapa.

Zvakaitika zvisina kunaka zvaungawana zvinosanganisira:

• Manyoka kana zvigaro zvakasununguka
• Dizziness kana kunzwa uchinetseka
• Nausea kana dumbu rinogumbuka
• Kuzvimba mumaoko ako, tsoka, kana zvitsitsinho
• Kushaya simba kana kuneta
• Kukosora kana zviratidzo zvekufema
• Zvirwere zvegumbo remuviri

Izvi zvakaitika zvisina kunaka zvinowanzoitika zvinowanzoitika uye zvinowanzoderera nekufamba kwenguva. Zvisinei, unofanira kutaurirana nachiremba wako kana vakava vanonetsa kana kukanganisa mabasa ako ezuva nezuva.

Kune zvakare zvimwe zvishoma zvisina kujairika asi zvakanyanya zvakakomba zvazvinoitika zvinoda kutarisirwa kwekurapa nekukurumidza. Kunyangwe izvi zvichishoma, zvakakosha kuzviziva.

Zvakaitika zvakakomba zvinoda kutarisirwa kwekurapa nekukurumidza zvinosanganisira:

• Matambudziko emoyo kana kurova kwemoyo kusingaite
• Dizziness yakanyanya kana kufenda
• Allergic reactions senge rash, kukwenya, kana kuoma kufema
• Nausea yakanyanya, kurutsa, kana manyoka
• Kubuda ropa kusingajairiki kana kupwanya
• Kuvhiringidzika kana shanduko mumamiriro epfungwa
• Kushaya simba kwemhasuru kwakanyanya

Kana iwe ukawana chero izvi zvakakomba zvazvinoitika, taura nachiremba wako nekukurumidza kana kutsvaga rubatsiro rwekurapa nekukurumidza. Kuchengeteka kwako ndiko kukosha kukuru, uye vanopa hutano vakashongedzerwa zvakanaka kubatsira kubata chero zviratidzo zvinonetsa.

Ndiani Asingafaniri Kutora Dextromethorphan ne Quinidine?

Mishonga iyi haina kuchengeteka kumunhu wese, uye chiremba wako achanyatsoongorora nhoroondo yako yezvokurapa asati akuvimbisa. Mamwe mamiriro ehutano nemishonga zvinogona kuita kuti kurapwa uku kusakodzere kana kuva nenjodzi.

Haufaniri kutora mushonga uyu kana uine mamwe mamiriro emoyo, kunyanya mhando dzakasiyana dzekusagadzikana kwemoyo kana kuvharika kwemoyo. Chikamu che quinidine chinogona kukanganisa sisitimu yemagetsi yemoyo wako, saka chiremba wako anogona kuda kutarisa rhythm yemoyo wako usati watanga kurapwa.

Vanhu vane chirwere chakakomba chechiropa kana itsvo vangave vasingakwanise kutora mushonga uyu zvakachengeteka. Muviri wako unoda chiropa netsvo zvine hutano kuti ugadzirise mushonga nemazvo, uye kushanda kwenhengo dzakakanganiswa kunogona kukonzera mazinga ane njodzi achivaka mumuviri wako.

Kana uri kutora mamwe mamwe mishonga, musanganiswa uyu ungave usingakodzere kwauri. Izvi zvinosanganisira mamwe antidepressants, zvinoderedza ropa, uye mamwe mishonga yemoyo inogona kukanganisa nenzira ine njodzi ne dextromethorphan uye quinidine.

Chiremba wako achadawo kuziva kana uine nhoroondo yezvirwere zveropa, kusagadzikana kwemagetsi, kana kana wakamirira kana kuronga kuva nepamuviri. Kuchengeteka kwemushonga uyu panguva yekuzvitakura hakuna kumiswa zvizere.

Dextromethorphan uye Quinidine Zita reBrand

Zita remhando yemushonga uyu musanganiswa ndiNuedexta. Iri ndiro chete zita reNuedexta rinotenderwa neFDA re dextromethorphan uye quinidine musanganiswa inowanikwa muUnited States.

Nuedexta inogadzirwa neAvanir Pharmaceuticals uye inouya mumacapsules ane 20 mg ye dextromethorphan uye 10 mg ye quinidine. Capsule imwe neimwe yakagadzirirwa kupa chiyero chaicho chemishonga miviri iyi inodiwa kurapwa kwePBA kunoshanda.

Pane dzimwe nguva paungawana mushonga uyu uchitaurwa nezita rawo re generic, asi parizvino, hapana mhando dze generic dziripo. Izvi zvinoreva kuti kazhinji uchawana zita remhando ye Nuedexta kana mushonga wako wazadzwa.

Mishonga iyi inouya mumabhodhoro ane makapisi makumi matanhatu kana makumi matatu, zvichienderana nemushonga wako uye inishuwarenzi yako. Murapi wako wemishonga anogona kukubatsira kunzwisisa mushonga wako chaiwo uye kupindura mibvunzo ipi neipi pamusoro pemishonga yaunogamuchira.

Dzimwe nzira dzekushandisa Dextromethorphan uye Quinidine

Parizvino, dextromethorphan uye quinidine ndiyo chete mushonga wakabvumirwa neFDA zvakananga kurapa pseudobulbar affect. Zvisinei, chiremba wako angatarisa dzimwe nzira kana mushonga uyu usingakukodzere kana usingapi rubatsiro rwakakwana.

Vamwe vanachiremba vanogona kunyora mamwe maantidepressants kunze kwemutemo kuti abatsire nePBA zviratidzo. Tricyclic antidepressants senge amitriptyline kana selective serotonin reuptake inhibitors (SSRIs) vakaratidza kumwe kubatsira muzvidzidzo zvekiriniki, kunyangwe vasina kubvumirwa zvakananga kurapa PBA.

Nzira dzisiri dzemishonga dzinogonawo kubatsira semishonga inowedzera. Kurapa kwekutaura, kubvunzurudzwa, uye nzira dzekugadzirisa dzinogona kukubatsira kudzora matambudziko emagariro uye emanzwiro anouya nePBA zviitiko.

Kushanda pamwe chete nenyanzvi yetsinga kana chiremba wepfungwa ane ruzivo rwePBA kunogona kukubatsira kuongorora zvese zvingasarudzwa. Vanogona kukubatsira kuyera mabhenefiti nenjodzi dzenzira dzakasiyana zvichienderana nemamiriro ako chaiwo uye mamwe mamiriro ehutano.

Chinhu chakanyanya kukosha kushanda pedyo nechikwata chako chekuchengetedza hutano kuti uwane nzira yekurapa inoshanda zvakanyanya kwauri. Usazeze kubvunza mibvunzo kana kuratidza zvinokunetsa nezvechirongwa chako chekurapa.

Ko Dextromethorphan uye Quinidine Zviri Nani Pane Zvimwe Zvirwere zvePBA?

Dextromethorphan ne quinidine ndiyo mushonga wakanakisa we pseudobulbar affect nekuti ndiyo chete mushonga wakabvumirwa zvakananga neFDA wechirwere ichi. Zvidzidzo zvekurapa zvakaratidza kuti zvinoshanda zvakanyanya kupfuura placebo mukuderedza zviitiko zvePBA.

Kana tichienzanisa nemishonga isiri pamutemo yakaita semishonga inorwisa kuora mwoyo, musanganiswa uyu wakadzidzwa zvakananga uye wakaonekwa uchishanda zvePBA. Zviedzo zvekurapa zvakaratidza kuti vanenge 85% yevanhu vaitora mushonga vakawana kuvandudzwa kunobatsira muzviratidzo zvavo zvePBA.

Kubatsirwa kwekuva nemushonga wakabvumirwa neFDA ndeyekuti unogona kunzwa wakavimbika nezve kuchengeteka kwake uye kushanda. Mushonga wakapfuura bvunzo dzakanyanya zvePBA, kusiyana nemimwe mishonga inoshandiswa kunze kwemutemo.

Zvisinei, "zvirinani" zvinoenderana nemamiriro ako ega. Vamwe vanhu vangapindura zvakanaka kumishonga imwe, kunyanya kana vaine mamwe mamiriro anoita kuti dextromethorphan ne quinidine vasakodzere kwavari.

Chiremba wako anogona kukubatsira kunzwisisa kuti mushonga uyu unoenzaniswa sei nedzimwe sarudzo zvichienderana nehutano hwako, mimwe mishonga yaunotora, uye zvinangwa zvako zvekurapa.

Mibvunzo Inowanzo Bvunzwa Nezve Dextromethorphan ne Quinidine

Q1. Dextromethorphan ne Quinidine Zvakachengeteka Here Kune Chirwere Chemoyo?

Mushonga uyu unoda kufunga zvakanyanya kana uine chirwere chemoyo, kunyanya mamwe marudzi ekusagadzikana kwemoyo. Chikamu che quinidine chinogona kukanganisa sisitimu yemagetsi yemoyo wako, iyo inogona kuva nedambudziko kune mamwe mamiriro emoyo.

Chiremba wako anogona kuda kuita electrocardiogram (ECG) usati watanga kurapwa kuti atarise rhythm yemoyo wako. Vachatarisawo rudzi rwako rwechokwadi rwechirwere chemoyo kuti vaone kana mushonga uyu wakakodzera kwauri.

Kana uine nhoroondo yematambudziko emoyo, usafungidzira kuti mushonga uyu hauna kuchengeteka kwauri. Vanhu vazhinji vane matambudziko emoyo vanogona kuutora zvakachengeteka nekutarisa kwakakodzera. Chiremba wako wemoyo uye chiremba anokurudzira mushonga vanogona kushanda pamwechete kuti vave nechokwadi chekuchengeteka kwako.

Mubvunzo 2. Ndoita Sei Kana Ndikashandisa Zvakanyanya Dextromethorphan uye Quinidine?

Kana ukatora zvakawanda kupfuura chiyero chawakanyorerwa, fonera chiremba wako kana nzvimbo yekudzora muchetura nekukasira. Kutora zvakawanda zve mushonga uyu kunogona kuva nenjodzi, kunyanya nekuda kwemigumisiro ye quinidine pamoyo wako.

Zviratidzo zvekuwandisa zvinogona kusanganisira dzungu rakanyanya, kufenda, kurova kwemoyo kusingaite, kusvotwa, kurutsa, kana kuvhiringidzika. Kana ukaona chero zviratidzo izvi mushure mekutora mushonga wakawanda, tsvaga rubatsiro rwekurapa nekukasira.

Usaedze "kugadzirisa" kuwandisa nekusvetuka chiyero chako chinotevera. Pane kudaro, tevera gwara remupi wako wehutano kana nzvimbo yekudzora muchetura nezvekuti ungatanga riini chirongwa chako chekushandisa mushonga.

Mubvunzo 3. Ndoita Sei Kana Ndikakanganwa Chiyero cheDextromethorphan uye Quinidine?

Kana ukakanganwa chiyero, chitora paunorangarira, kunze kwekunge yava nguva yechiyero chako chinotevera. Muchiitiko ichocho, svetuka chiyero chawakakanganwa uye uenderere mberi nechirongwa chako chekushandisa mushonga.

Usambofa wakatora zviyero zviviri panguva imwe chete kuti ugadzirise chiyero chawakakanganwa. Izvi zvinogona kuwedzera njodzi yako yemigumisiro, kunyanya matambudziko emoyo kubva ku quinidine yakawanda panguva imwe chete.

Kana iwe uchikanganwa zviyero kazhinji, funga kumisa zviyeuchidzo zvefoni kana kushandisa chirongwa chemushonga kuti zvikubatsire kuramba uchidaro. Kushandisa mushonga nguva dzose kwakakosha kuchengetedza kutonga kwakagadzikana kwezviratidzo zvako zvePBA.

Mubvunzo 4. Ndingamira Rini Kutora Dextromethorphan uye Quinidine?

Haufanire kumira kutora mushonga uyu usati wataura nachiremba wako. PBA inowanzoita mamiriro echronic, uye kumisa kurapwa kazhinji zvinoreva kuti zviratidzo zvako zvichadzoka.

Chiremba wako angatarisa kuderedza kana kumisa mushonga kana mamiriro ako ekuongorora akavandudzika, kana ukawana matambudziko asingashiviriki, kana kana mamwe mamiriro ehutano achiita kuti kurapwa kuenderere mberi kusachengeteka.

Kana uchida kumisa kutora mushonga, chiremba wako anogona kukurudzira kuderedza zvishoma nezvishoma muyero wako pane kumisa kamwechete. Izvi zvinobatsira kudzivirira chero zvingaitika zvekubvisa uye zvinobvumira kunyatso tarisa zviratidzo zvako zvePBA.

Q5. Ndinganwe Doro Ndiri Kutora Dextromethorphan uye Quinidine?

Unofanira kudzivisa doro kana kurigumira zvakanyanya uchitora mushonga uyu. Doro rinogona kuwedzera mhedzisiro yekunyaradza ye dextromethorphan uye rinogona zvakare kukanganisa rhythm yemoyo wako, izvo zvinogona kuva njodzi kana zvakasanganiswa ne quinidine.

Kana ukasarudza kunwa doro dzimwe nguva, taura nachiremba wako nezve miganho yakachengeteka zvichienderana nehutano hwako hwega. Vanogona kupa gwara rakatarisa mamiriro ako uye mamwe mishonga yaungave uchitora.

Rangarira kuti doro rinogonawo kuwedzera mamwe mamiriro ekuongorora uye rinogona kuita kuti zviratidzo zvako zvePBA zvinyanye kuoma kubata. Hutano hwako hwese uye kudzora zviratidzo zvinogona kuvandudzika nekunwa doro shoma.