Chii chinonzi Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide: Zvinoshandiswa, Mishonga, Migumisiro Yemuviri, nezvimwe

Emtricitabine-rilpivirine-uye-tenofovir-alafenamide mushonga unosanganiswa unoshandiswa kurapa hutachiona hweHIV muvanhu vakuru nevechidiki. Iri piritsi rimwe chete rine mishonga mitatu yakasiyana yeHIV inoshanda pamwechete kubatsira kudzora hutachiona mumuviri wako.

Ungangoziva mushonga uyu nezita rawo rekuti Odefsey. Yakagadzirirwa kuita kuti kurapwa kweHIV kuve nyore nekubatanidza mishonga mitatu inoshanda mupiritsi rimwe chete rezuva nezuva, izvo zvinogona kukubatsira kunamatira kuronga kwako kurapwa zviri nyore.

Chii chinonzi Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide?

Mushonga uyu ndiyo nzira yakazara yekurapa HIV mupiritsi rimwe chete. Inobatanidza mhando nhatu dzakasiyana dzemishonga yeHIV inorwisa hutachiona nenzira dzakasiyana kudzivirira kuti isawedzere mumuviri wako.

Zvikamu zvitatu zvinoshanda sechikwata. Emtricitabine na tenofovir alafenamide vese vanodzivirira nucleoside reverse transcriptase, nepo rilpivirine isiri-nucleoside reverse transcriptase inhibitor. Funga nezvavo sekudzivisa nzira dzakasiyana dzinodiwa nehutachiona hweHIV kuti hubereke.

Iyi musanganiswa inoonekwa seyakazara kurapwa, zvinoreva kuti haufanirwe kutora mamwe mishonga yeHIV nayo. Chiremba wako achakupa izvi kana zvakakodzera mamiriro ako chaiwo uye mutoro wehutachiona.

Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide inoshandiswa chii?

Mushonga uyu unoshandiswa zvakanyanya kurapa hutachiona hweHIV-1 muvanhu vakuru nevechidiki vanorema angangoita 35 kilograms (anenge 77 pounds). Yakagadzirirwa vanhu vari kutanga kurapwa kweHIV kekutanga kana kuchinja kubva kune imwe nzira yekurapa HIV.

Chiremba wako anowanzo kupa izvi kana mutoro wako wehutachiona uri pasi pe100,000 makopi pa milliliter yeropa. Iyi threshold yakakosha nekuti rilpivirine, imwe yezvikamu, inoshanda zvakanyanya kana mutoro wehutachiona usiri wakanyanya kukwirira.

Inoshandiswawo kune vanhu vanoda kurerutsa kurapwa kwavo HIV. Kana iwe uchitora mapiritsi akawanda eHIV zuva rese, chiremba wako anogona kukuchinjira kune iyi sarudzo yekutora kamwe chete pazuva kuti uite kuti maitiro ako ave nyore kubata.

Maitiro anoita Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide?

Mishonga iyi inoshanda nekudzivirira HIV kubva pakugadzira makopi ayo mumuviri wako. Chikamu chimwe nechimwe chinotarisana nedanho rakasiyana mukugadzirwa kwehutachiona, zvichigadzira zvipingamupinyi zvakawanda izvo HIV risingakwanise kukunda nyore nyore.

Emtricitabine uye tenofovir alafenamide inoshanda nekutevedzera zvivakwa izvo HIV inoda kugadzira zvinhu zvayo zvemajini. Kana hutachiona huchiedza kushandisa zvivakwa izvi zvekunyepedzera, haigone kupedzisa maitiro ekukopa uye inonamatira.

Rilpivirine inoshanda zvakasiyana nekudzivirira zvakananga enzyme inonzi reverse transcriptase iyo HIV inoda kushandura zvinhu zvayo zvemajini kuita chimiro maseru ako anogona kuverenga. Pasina iyi enzyme ichishanda nemazvo, hutachiona hahugone kubatanidzwa mumasero ako.

Izvi zvinoonekwa seyakati simba reHIV. Inoshanda kune vanhu vazhinji vane HIV, asi inogona kunge isiri sarudzo yakanakisa kana iwe uine hutachiona hwakanyanya kana mamwe marudzi ekudzivirira zvinodhaka.

Ndingatora sei Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide?

Tora mushonga uyu sezvinorayirwa nachiremba wako, kazhinji piritsi rimwe kamwe chete pazuva uine chikafu. Kuitora nechikafu kwakakosha nekuti kunobatsira muviri wako kutora chikamu cherilpivirine nemazvo.

Unofanira kuitora nechikafu, kwete kungoti snack. Chikafu chine macalorie angangoita 390 chinoshanda zvakanyanya. Izvi zvinogona kuva kudya kwemangwanani, masikati, kana chisvusvuro - chero chinokodzera purogiramu yako, asi edza kuitora panguva imwe chete zuva rega rega.

Medza piritsi rose nemvura. Usapwanya, kutsenga, kana kupatsanura piritsi nekuti izvi zvinogona kukanganisa nzira iyo mushonga unovhurwa mumuviri wako. Kana uine dambudziko rekumedza mapiritsi, taura nachiremba wako nezvesarudzo dzako.

Edza kugadza tsika yekutora mushonga panguva imwechete zuva rega rega. Izvi zvinobatsira kuchengetedza huwandu hwemushonga hwakagadzikana muropa rako uye zvinoita kuti zvikuyeuchidzwe nyore dose yako.

Ndingatora Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide kwenguva yakareba sei?

Unofanirwa kutora mushonga uyu kwenguva yakareba sezvinokurudzirwa nachiremba wako, izvo zvinowanzoitika kwehupenyu hwese. Kurapa HIV ibasa renguva refu, uye kumisa mushonga kunogona kubvumira hutachiona kuti huwedzerezve uye hugone kuita kuramba.

Chiremba wako achatarisa kufambira mberi kwako kuburikidza nekuongororwa kweropa nguva dzose kunotarisa huwandu hwehutachiona hwako uye CD4 count. Miedzo iyi inobatsira kuona kuti mushonga uri kushanda sei uye kana uchida kuenderera mberi nekurapa kumwe chete.

Usambomira kutora mushonga uyu usati wataura nachiremba wako kutanga, kunyangwe ukanzwa zvakanaka zvachose. HIV inogona kunge iripo mumuviri wako isingakonzere zviratidzo, uye kumisa kurapwa kamwe kamwe kunogona kutungamira kuhutachiona huchidzoka zvakare zvakasimba kupfuura kare.

Kana uri kusangana nemigumisiro kana uine matambudziko nemushonga, kurukura izvi nemupi wako wehutano. Vanogona kukwanisa kugadzirisa kurapwa kwako kana kukubatsira kubata chero nyaya dziri kukuitira.

Ndezvipi Zvakaipa zveEmtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide?

Semishonga yese, iyi musanganiswa inogona kukonzera migumisiro, kunyangwe kwete munhu wese anoiziva. Mazhinji emigumisiro yakapfava uye inowanzoita nani sezvo muviri wako uchigadzirisa kumushonga mumavhiki mashoma ekutanga.

Heano migumisiro yakajairika yaungasangana nayo sezvo muviri wako uchijaira mushonga:

• Kutemwa nemusoro
• Matambudziko ekurara kana kurota zvisina kujairika
• Dizziness
• Nausea
• Kuneta
• Diarhea
• Mota yeganda

Mhedzisiro iyi inowanzoita kuti isanyanye kunetsa mushure memwedzi wekutanga wekurapwa. Kana dzikagara kana kuva dzinonetsa, chiremba wako anogona kukurudzira nzira dzekudzidzorera.

Vamwe vanhu vanogona kusangana nemhedzisiro isingawanzoitiki asi yakakomba inoda kutariswa kwechiremba. Kunyange izvi zvisingaitiki kune vanhu vazhinji, zvakakosha kuziva nezvazvo:

• Kushungurudzika kwakanyanya kana shanduko dzemafungiro
• Matambudziko eitsvo (kuchinja mukuyerera kwemvura, kuzvimba)
• Matambudziko emapfupa (kurwadziwa kwemapfupa kusinganzwisisike kana mabhureki)
• Matambudziko echiropa (kushanduka kweganda kana maziso, weti yakasviba)
• Lactic acidosis (kuneta kusinganzwisisike, kurwadziwa mudumbu, matambudziko ekufema)
• Kusangana kweganda kwakanyanya

Taura nachiremba wako nekukasira kana ukaona chero mhedzisiro yakakomba iyi. Kupindira kwekutanga kunogona kubatsira kudzivirira matambudziko uye kuona kuti kurapwa kwako kunoramba kuri munzira.

Ndiani Asingafaniri Kutora Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide?

Mishonga iyi haina kukodzera munhu wese. Chiremba wako achanyatsoongorora nhoroondo yako yekurapa uye mamiriro ako ehutano aripo usati akuraira kuti ave nechokwadi chekuti yakachengeteka kwauri.

Haufaniri kutora mushonga uyu kana uine chirwere cheitsvo chakakomba kana uri pa dialysis. Zvikamu zvinogona kukanganisa kushanda kweitsvo, saka vanhu vane matambudziko makuru eitsvo vanoda dzimwe nzira dzekurapa.

Vanhu vane chirwere chechiropa chakakomba, kusanganisira hepatitis B, vangave vasiri vakanaka vekushandisa mushonga uyu. Kana uine hepatitis B, kumisa mushonga uyu kamwe kamwe kunogona kukonzera kuti hepatitis yako iwedzere, saka kuongorora kwakakosha kunodiwa.

Mishonga iyi ingasava sarudzo yakanaka kana uine hutachiona hwakanyanya (kupfuura 100,000 makopi pa milliliter) kana kana wakagadzira kuramba kune chero chimwe chezvikamu zvitatu. Chiremba wako achaita bvunzo dzekutarisa kuramba usati akuraira.

Vakadzi vane pamuviri vanofanira kukurukura dzimwe sarudzo nachiremba wavo, sezvo musanganiswa uyu usingawanzo sarudzwa pakutanga panguva yekuzvitakura. Kune mamwe mishonga yeHIV ine ruzivo rwakawanda rwekuchengeteka panguva yekuzvitakura.

Zita reBrand reEmtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide

Zita rebrand remushonga uyu musanganiswa ndiOdefsey. Inogadzirwa neGilead Sciences uye yakatenderwa neFDA muna 2016 yekurapa hutachiona hweHIV-1.

Odefsey inowanikwa setableti imwechete ine 200 mg ye emtricitabine, 25 mg ye rilpivirine, uye 25 mg ye tenofovir alafenamide. Musanganiswa uyu chaiwo uye kuyera hausi kuwanikwa muchimiro chegeneric.

Paunenge uchitaura nachiremba wako kana muzvinemishonga, unogona kuita referenzi kwairi nezita rebrand Odefsey kana zita rakazara regeneric. Mazwi ese ari maviri anoreva mushonga mumwechete.

Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide Dzimwe Sarudzo

Mamwe marongero eHIV etableti imwechete anowanikwa kana mushonga uyu usingakukodzere. Chiremba wako anogona kukubatsira kuwana imwe sarudzo inokodzera zvaunoda uye mamiriro ako ehutano.

Dzimwe sarudzo dzinosanganisira Biktarvy (bictegravir, emtricitabine, uye tenofovir alafenamide), iyo inowanzo sarudzwa kune vanhu vane hutachiona hwakanyanya. Triumeq (dolutegravir, abacavir, uye lamivudine) imwe sarudzo, kunyanya kune vanhu vasingakwanise kutora tenofovir.

Genvoya (elvitegravir, cobicistat, emtricitabine, uye tenofovir alafenamide) imwe sarudzo yetableti imwechete inoshanda zvakanaka kune vanhu vazhinji. Chiremba wako anogonawo kufunga nezvemisanganiswa yekare seAtripla kana Complera, zvichienderana nemamiriro ako chaiwo.

Sarudzo pakati pezvisarudzo izvi zvinoenderana nezvinhu zvakaita sehutachiona hwako, basa reitsvo, mamwe mishonga yaunotora, uye mikana yekudyidzana kwemishonga. Chiremba wako achakubatsira kuyera zvakanaka nezvakaipa zvesarudzo imwe neimwe.

Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide Zviri Nani Pane Biktarvy Here?

Mishonga yese iri miviri inoshanda kurapa HIV, asi ine simba rakasiyana uye inogona kunge yakakodzera vanhu vakasiyana. Biktarvy inowanzofungidzirwa kuti ine simba rakawanda uye inogona kushandiswa muvanhu vane huwandu hwehutachiona hwakakwira.

Biktarvy ine integrase inhibitor (bictegravir), iyo kirasi itsva yemushonga weHIV inowanzo shanda nekukurumidza uye ine kushamwaridzana kwemishonga kushoma. Haireve chikafu chekutorwa, zvichiita kuti zvive nyore kune vamwe vanhu.

Zvisinei, Odefsey inogona kunge iri sarudzo iri nani kune vanhu vakambotora mishonga yeHIV uye vakagadzira mamwe maitiro ekudzivirira. Inowanzoitawo kuti pave nemigumisiro mishoma yemudumbu mune vamwe vanhu.

Chiremba wako achafunga nezve huwandu hwehutachiona hwako, nhoroondo yekurapa, basa reitsvo, mamwe mishonga, uye zvaunofarira paunenge uchisarudza pakati pesarudzo idzi. Hapana sarudzo yakanaka yese - zvinoenderana nemamiriro ako ega.

Mibvunzo Inowanzo Bvunzwa Nezve Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide

Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide Yakachengeteka Kune Vanhu Vane Chirwere Cheitsvo Here?

Mushonga uyu unofanirwa kushandiswa nekuchenjerera muvanhu vane matambudziko eitsvo. Chiremba wako achaedza basa reitsvo yako usati watanga kurapwa uye achaironda nguva dzose paunenge uchitora mushonga.

Kana uine chirwere cheitsvo chinyoro, chiremba wako angangodaro achanyora mushonga uyu asi achakutarisa zvakanyanya. Vanhu vane chirwere cheitsvo chakati wandei kusvika chakaipa kana avo vari pa dialysis vanowanzo shandisa mishonga yeHIV yakasiyana iyo yakachengeteka kune itsvo.

Chikamu chetenofovir chinogona kukanganisa basa reitsvo nekufamba kwenguva, saka kuongorora nguva dzose kunobatsira kubata chero matambudziko ekutanga. Kana basa reitsvo yako richichinja, chiremba wako angangoda kugadzirisa chirongwa chako chekurapa.

Ndingaita Sei Kana Ndikashandisa Zvakanyanya Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide?

Kana ukatora zvinopfuura zvaakakuraira netsaona, taura nachiremba wako kana nzvimbo inobata chepfu nekukasira. Usamirira kuti uone kana uchinzwa kurwara - zviri nani kutsvaga mazano ekurapa nekukasira.

Kutora mushonga uyu wakawanda kunogona kuwedzera njodzi yako yekuwana mhedzisiro, kunyanya avo vanokanganisa itsvo dzako, chiropa, kana rhythm yemoyo. Vapi vehutano vanogona kukutarisa kuti uone chero zviratidzo zvematambudziko uye kupa rutsigiro kana zvichidikanwa.

Chengeta bhodhoro remushonga newe paunotsvaga kutarisirwa kwekurapa kuitira kuti vapi vehutano vagone kuona chaizvo zvawakatora uye zvakawanda sei. Ruzivo urwu runovabatsira kupa kutarisirwa kwakanaka.

Ndoita Sei Kana Ndakakanganwa Dose yeEmtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide?

Kana ukakanganwa dose, itore paunorangarira, chero zvakadaro mukati meawa gumi nemaviri yenguva yako yenguva dzose. Ita shuwa kuti unotora nechikafu, sekungofanana nedose yako yenguva dzose.

Kana zvapfuura maawa gumi nemaviri kubva panguva yako yenguva dzose, siya dose yakakanganwa uye tora dose yako inotevera panguva yenguva dzose. Usatore madosi maviri panguva imwe chete kuti ugadzirise dose yakakanganwa.

Kukanganwa madosi dzimwe nguva hakuzokonzeri matambudziko nekukasira, asi edza kutora mushonga wako nguva dzose sezvinobvira. Madosi akakanganwa kazhinji anogona kubvumira hutachiona kuti hukure kuramba uye kuita kuti kurapwa kushande zvishoma.

Ndingamira Rini Kutora Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide?

Unofanira kungomira kutora mushonga uyu pasi pekutariswa kwachiremba wako. Kurapwa kweHIV kazhinji kunogara hupenyu hwese, uye kumira kunogona kubvumira hutachiona kuti huwedzerezve uye zvichibvira kukudziridza kuramba kumishonga.

Chiremba wako anogona kuchinja hutongi hwako hweHIV kana ukawana mhedzisiro, kuramba kwemishonga, kana kana zvitsva, zvirinani sarudzo dzikawanikwa. Zvisinei, iwe unowanzochinja kune imwe mishonga yeHIV pane kumisa kurapwa zvachose.

Kana muchifunga kumira mushonga uyu nekuda kwemigumisiro kana dzimwe nyaya, taura nachiremba wenyu kutanga. Vanogona kubatsira kudzora migumisiro kana kutsvaga mamwe marapirwo anokushandirai zviri nani.

Ndingatora Emtricitabine-Rilpivirine-uye-Tenofovir-Alafenamide nemimwe mishonga here?

Mishonga iyi inogona kushanda pamwe chete nemimwe mishonga, saka zvakakosha kuti muudze chiremba wenyu nezve mishonga yese, zvinowedzerwa, uye zvigadzirwa zvemiti zvaunotora. Dzimwe nzira dzekushanda pamwe chete dzinogona kuita kuti mushonga weHIV usashande zvakanaka kana kuwedzera migumisiro.

Antacids, proton pump inhibitors (semuenzaniso omeprazole), uye H2 blockers (semuenzaniso ranitidine) zvinogona kuderedza kunyudzwa kwe rilpivirine. Kana muchida mishonga iyi, chiremba wenyu achakukurudzirai nezve nguva yakakodzera kudzivirira kushanda pamwe chete.

Mamwe maantibiotics, antifungals, uye mishonga yekubata zvirwere zvekubata muviri inogonawo kushanda pamwe chete nemushonga uyu. Chiremba wenyu nemu pharmacist vanogona kukubatsirai kudzora nzira idzi dzekushanda pamwe chete zvakachengeteka vachive nechokwadi chekuti mishonga yenyu yese inoshanda zvakanaka.