Chii chinonzi Esmolol: Kushandiswa, Madosi, Migumisiro Yemativi uye Zvimwe

Esmolol mushonga unovhara beta-blocker unopiwa kuburikidza neIV muzvipatara kuti utonge nekukurumidza high blood pressure uye mwoyo unokurumidza panguva yekukurumidzira kwekurapa. Fungidzira sebrake chaiyo, inokurumidza kuita yemuviri wako wecardiovascular iyo vanachiremba vanogona kuvhura nekudzima sezvinodiwa. Mushonga uyu unoshanda mukati memaminitsi uye unopera nekukurumidza, zvichiita kuti ubatsire zvikuru kana zvikwata zvekurapa zvichida kukurumidza asi kwenguva pfupi kutonga kwemwoyo uye blood pressure.

Chii chinonzi Esmolol?

Esmolol mushonga webeta-blocker uyo wekirasi yemishonga inonzi cardioselective beta-1 adrenergic receptor blockers. Inoshanda nekudzivisa ma receptors chaiwo mumoyo mako anopindura adrenaline uye mahomoni akafanana ekushushikana. Kusiyana nemamwe ma beta-blockers aunogona kutora semapiritsi ezuva nezuva, esmolol inongopiwa kuburikidza neIV line muzvipatara.

Chinonyanya kuita kuti esmolol ive yakasarudzika ndiyo nguva yayo shoma yekushanda. Mushonga unotanga kushanda mukati me1-2 maminitsi ekupiwa uye mhedzisiro yayo inopera mukati me10-30 maminitsi mushure mekunge infusion yamira. Izvi zvinopa vanachiremba kutonga kwakanyatsojeka pamwoyo wako uye blood pressure panguva dzakakosha.

Chii chinonzi Esmolol chinoshandiswa?

Esmolol inonyanya kushandiswa kutarisira kuwedzera kamwe kamwe mu blood pressure uye mwoyo panguva yekuvhiyiwa, maitiro ekurapa, kana mamiriro ekukurumidzira ekurapa. Vanachiremba vanosvika kumushonga uyu kana vachida kukurumidza asi kwenguva pfupi cardiovascular control iyo inogona kugadziriswa nyore nyore kana kumiswa.

Mamiriro akajairika aunogona kugamuchira esmolol anosanganisira panguva yekuvhiyiwa apo blood pressure yako kana mwoyo unova wakanyanya kukwirira, mukamuri rekukurumidzira hypertensive crises, kana mu intensive care unit kana mamwe mishonga ye blood pressure isingashande nekukurumidza zvakakwana. Inoshandiswawo kana uchibuda mune anesthesia uye muviri wako wecardiovascular uchida kutungamirirwa zvinyoro nyoro kudzokera kune zvakajairika.

Kazhinji, esmolol inogona kushandiswa kune matambudziko emoyo kana chiremba achida kuyedza kuti moyo wako unopindura sei kurapa kwe beta-blocker usati wakatanga mushonga unotora nguva refu. Vamwe varwere vanoiwana panguva yezvipatara zvakaita semamwe marudzi ekuvhiya ziso uko kudzora ropa kwakakosha.

Esmolol Inoshanda Sei?

Esmolol inoshanda nekudzivisa beta-1 receptors mumhasuru dzemoyo wako, izvo zvakaita semaswitch anopindura adrenaline nemamwe mahomoni ekushushikana. Kana ma receptors aya akavharwa, moyo wako unokunda zvishoma nezvishoma uye nesimba shoma, izvo zvinoderedza ropa rako.

Uyu unoonekwa semushonga wakasimba zvishoma maererano nemigumisiro yawo yakananga, asi zvakare inogara kwenguva pfupi. Muviri wako une ma enzymes akakosha muropa rako anokurumidza kuparadza esmolol, ndosaka migumisiro yayo ichinyangarika nekukurumidza kana infusion ye IV yamira. Iyi pfuma yakasarudzika inoita kuti ive yakachengeteka zvakanyanya kupfuura beta-blockers inotora nguva refu mumamiriro ezvinhu ekukurumidzira.

Mushonga uyu unosarudzwa kune beta-1 receptors, zvinoreva kuti inonyanya kukanganisa moyo wako panzvimbo pemamwe nhengo dzakadai semapapu ako. Kusarudzwa uku kunoita kuti ive yakachengeteka kune vanhu vane mamiriro ekufema, kunyangwe isina njodzi zvachose.

Ndingatora Sei Esmolol?

Hauzozvitore esmolol iwe pachako - mushonga uyu unongopihwa nevashandi vehutano vakadzidziswa kuburikidza ne IV line muzvipatara. Chikwata chekurapa chichatanga nekuisa dose, iyo yakawanda yekutanga huwandu, ichiteverwa nekuenderera mberi infusion iyo inogona kugadziriswa zvichienderana nekuti muviri wako unopindura sei.

Vanachiremwa venyu navanachiremba vachatarisa kukurumidza kwemoyo wenyu, kudzvanywa kweropa, uye mamiriro enyu ese nguva dzese pamunenge muchigamuchira esmolol. Vachachinja muyero maminitsi mashoma ega ega kana zvichidikanwa kuti vawane chiyero chakakodzera chemamiriro enyu chaiwo. Mitengo yakajairika yekupinza inobva pamadosi akaderera kwazvo kusvika kumari yakakwira, zvichienderana nekupindura kwemuviri wenyu uye zvinodiwa zvekurapa.

Sezvo muchave muri muchipatara, hamufaniri kunetseka nezvekuita kwechikafu kana nguva yekudya. Chikwata chekurapa chinobata zvese zvekutonga nekutarisa. Basa renyu nderekuzorora uye regai mushonga uite basa rawo apo nyanzvi dzehutano dzichitarisa zvakanyanya kuti muri kupindura sei.

Ndingatora Esmolol Kwenguva Yakareba Sei?

Esmolol inowanzo shandiswa kwenguva pfupi, kazhinji kubva kumaminitsi mashoma kusvika kumaawa akati wandei, zvichienderana nemamiriro enyu ekurapa. Varwere vazhinji vanoiwana panguva yekuvhiwa, maitiro ekurapa, kana zviitiko zvakanyanya zvinoda kukurumidza asi kwenguva pfupi kutonga kwemoyo nemitsipa.

Kureba kunoenderana zvachose nezvinodiwa zvenyu zvekurapa uye kuti muviri wenyu unopindura sei kurapwa. Panguva yekuvhiwa, mungaiwana chete kwenguva yechirongwa. Muzviitiko zvekukurumidzira, chikwata chekurapa chingashandisa kwemaawa mashoma pavanenge vachigadzirisa mamiriro enyu uye vachikuisai kumishonga yenguva refu kana zvichidikanwa.

Vanachiremba venyu vachaenderera mberi vachiongorora kana muchiri kuda mushonga uye vachauisa pakarepo kana hurongwa hwenyu hwemoyo nemitsipa hwagadzikana. Nekuti esmolol inopera nekukurumidza, vanogona kuimisa nyore nyore uye kuona kuti muviri wenyu unopindura sei mumaminitsi.

Ndezvipi Zvakaipa zveEsmolol?

Semishonga yese, esmolol inogona kukonzera mhedzisiro, kunyangwe vanhu vazhinji vachiigamuchira zvakanaka panguva yekushandiswa kwenguva pfupi. Mhedzisiro inowanzoitika ine hukama nechiito chayo chekutanga chekunonotsa kukurumidza kwemoyo wenyu nekudzikisa kudzvanywa kweropa.

Hezvino zvinogona kukonzera matambudziko, uchifunga kuti timu yako yezvokurapa iri kukutarisa zvakanyanya uye inogona kuchinja kana kumisa mushonga kana matambudziko akamuka:

• Kuderera kweropa (hypotension), izvo zvingakonzera kuti unzwe dzungu kana kuti musoro wako urwadze
• Kukurumidza kwemoyo (bradycardia), kunyangwe izvi zvichiwanzova mhedzisiro yainangwa
• Kuneta kana kusava nesimba
• Kusvotwa kana dumbu rinogumbuka
• Kurwadziwa kwemusoro
• Dzungu
• Kuvhiringidzika kana kunzwa kufinyama mupfungwa
• Kurwadziwa kana kutsamwa panzvimbo yeIV

Izvi zvinowanzoitika zvinowanzoitika zvinyoro uye zvinogadzirisa nekukurumidza kana mushonga wamiswa kana dosi yakaderedzwa. Chikwata chako chehutano chine ruzivo mukugadzirisa izvi zvinokonzeresa uye chichaita shanduko sezvinodiwa.

Zvimwe zvinokonzera matambudziko asi zvisingawanzoitiki zvinogona kusanganisira kudonha kwakanyanya kweropa, kukurumidza kwemoyo zvakanyanya, kana matambudziko emoyo. Kazhinji, vamwe vanhu vanogona kusangana nematambudziko ekufema, kunyanya kana vane mamiriro ezvinhu emapapu. Maitiro eAllergic anogoneka asi haawanzoitiki.

Mashoko akanaka ndewekuti nekuti esmolol inoshanda nekukurumidza uye inobuda mumuviri wako nekukurumidza, matambudziko mazhinji anogadzirisa mukati memaminitsi ekumisa infusion. Iyi rapid reversibility ndechimwe chezvinhu zvakakosha zvekuchengetedza izvo zvinoita kuti mushonga uyu uve wakakosha munzvimbo dzekuchipatara.

Ndiani Asingafaniri Kutora Esmolol?

Esmolol haina kukodzera munhu wese, uye timu yako yezvokurapa ichanyatsoongorora nhoroondo yako yezvokurapa usati washandisa mushonga uyu. Sarudzo yekushandisa esmolol inoenderana nekuyera mabhenefiti achipesana nenjodzi dzinogona kuitika mumamiriro ako chaiwo.

Vanhu vanowanzoita vasina kukodzera kugamuchira esmolol vanosanganisira avo vane mamwe matambudziko emoyo semuenzaniso akakomba moyo block, kukurumidza kwemoyo zvakanyanya, kana kukundikana kwemoyo kwakanyanya. Kana uine mamiriro anonzi cardiogenic shock, uko moyo wako usingakwanise kupomba ropa rakakwana kuti risangane nezvido zvemuviri wako, esmolol inogona kuita izvi zvakanyanya.

Asthma yakanyanya kana matambudziko ekufema anogonawo kuita kuti esmolol ive njodzi, kunyangwe iri nyoro kumapapu kupfuura mamwe mabhuroka-beta. Vanhu vane mhando dzakasiyana dzezvinetso zvemidzi yeropa kana avo vari kutora mishonga inogona kuita zvine njodzi neesmolol vanoda kufungwa kwakakosha.

Zvisinei, mamiriro ekukurumidzira dzimwe nguva anoda kuti vanachiremba vashandise mishonga pasinei nekunetseza uku, vaine kuongorora kwakawedzerwa uye matanho ekuchengetedza. Chikwata chako chekurapa chichayerera zvinhu izvi zvakanyatsonaka uye chine zvirongwa zvekugadzirisa chero matambudziko anogona kumuka.

Mazita eBrand eEsmolol

Esmolol inowanikwa kazhinji pasi pezita rekuti Brevibloc, iro ndiro vhezheni inozivikanwa zvakanyanya yemushonga uyu. Unogonawo kuona ichinzi "esmolol hydrochloride" munzvimbo dzekuchipatara.

Vagadziri vakasiyana vanogona kugadzira mhando dzakajairika dzeesmolol, asi dzese dzine chinhu chimwe chete chinoshanda uye dzinoshanda nenzira imwechete. Kuwanda uye kurongwa kunogona kusiyana zvishoma pakati pemhando, asi chikwata chako chehutano chichabata zvese zvakadzama zvehunyanzvi nezvechigadzirwa cha vari kushandisa.

Zvimwe zvingashandiswa panzvimbo peEsmolol

Kune dzimwe nzira dzakawanda dzekushandisa panzvimbo peesmolol, imwe neimwe iine hunhu hwakasiyana hunoita kuti ive yakakodzera mamiriro akasiyana. Sarudzo inoenderana nekuti vanachiremba vanoda sei kuti mushonga ushande nekukurumidza, kuti vanoda kuti mhedzisiro igare kwenguva yakareba sei, uye mamiriro ako chaiwo ehutano.

Mishonga yekudzikisa ropa inoshanda kwenguva pfupi inosanganisira nicardipine kana clevidipine, iyo inoshanda panzira dzakasiyana neesmolol. Kuti udzore kwenguva refu, vanachiremba vanogona kushandisa metoprolol, propranolol, kana mamwe mabhuroka-beta anogara kwenguva refu asi anotora nguva yakawanda kuti atange kushanda.

Labetalol imwe nzira inoshanda pane ese beta uye alpha receptors, ichipa kudzora kweropa kuburikidza nemaitiro akasiyana zvishoma. Imwe neimwe yenzira idzi ine zvainobatsira nezvazvinokanganisa, uye chikwata chako chekurapa chichasarudza zvichibva pazvido zvako zvakakosha uye mamiriro ako ekurapa.

Ko Esmolol Ari Nani Kudarika Metoprolol?

Esmolol na metoprolol vese vanodzora beta, asi vanoshanda zvakasiyana uye havana kuenzaniswa zvakananga maererano nekuva "vakanaka" kupfuura mumwe. Sarudzo pakati pavo inoenderana zvachose nemamiriro ako ekurapa uye zviri kuedza kuita vanachiremba vako.

Chinhu chikuru chinobatsira Esmolol ndechokuti inoshanda kwenguva pfupi, zvichiita kuti ive yakakwana mumamiriro ezvinhu apo vanachiremba vanoda kudzora kwakajeka, kwenguva pfupi kunogona kudzoserwa nyore nyore. Metoprolol, kune rumwe rutivi, inogara kwenguva refu uye yakakodzera kurapwa kwenguva refu kweropa rakakwira kana mamiriro emoyo.

Funga nezve esmolol sechishandiso chekururamisa chekushandiswa kwenguva pfupi, nepo metoprolol yakafanana nekurapa kwakagadzikana, kwenguva refu. Mumamiriro ezvinhu ekukurumidzira kana panguva yekuvhiya, kutanga nekukurumidza kweesmolol uye kubviswa kunoita kuti isakoshe. Kuti utarise mamiriro emoyo ezuva nezuva, mhedzisiro yeMetoprolol inogara kwenguva refu inoshanda.

Chikwata chako chekurapa chichasarudza mushonga wakakodzera zvichienderana nekuti unoda kudzora nekukurumidza, kwenguva pfupi kana manejimendi enguva refu yemamiriro ako emwoyo.

Mibvunzo Inowanzo Bvunzwa Nezve Esmolol

Ko Esmolol Akachengeteka Kune Vanhu vane Chirwere cheShuga?

Esmolol inogona kushandiswa zvakachengeteka muvanhu vane chirwere cheshuga, kunyangwe ichida kunyatsoongororwa. Kusiyana nemamwe ma beta-blockers, esmolol haina kukwanisa kuvhara zviratidzo zveyambiro zveshuga yakaderera yeropa, asi inogona kukanganisa maitiro emuviri wako kune shanduko mumazinga eglucose yeropa.

Vashandi venyu vezvokurapa vachatarisa shuga yeropa renyu zvakanyanya kana muine chirwere cheshuga uye muchipiwa esmolol. Nguva pfupi yekushanda inoita kuti ive yakachengeteka kupfuura mamwe ma beta-blockers anogara achishanda nekuti chero mhedzisiro pakudzora shuga yeropa ichagadziriswa nekukurumidza kana infusion yamira.

Ndingaita Sei Kana Ndikapiwa Esmolol Yakawandisa Netsaona?

Hamufaniri kunetseka nezve kapiwa esmolol yakawandisa netsaona nekuti nyanzvi dzezvekurapa dzakadzidziswa ndidzo dzinodzora maitiro ese ekupa mushonga. Mushonga uyu unopiwa kuburikidza neIV infusions inotariswa zvakanyanya nemidziyo yekuyera.

Kana overdose ikaitika, timu yenyu yezvokurapa ingamisa infusion nekukurumidza uye ichapa rutsigiro. Nekuti esmolol inobuda mumuviri wenyu nekukurumidza, mhedzisiro yakawanda yeoverdose ingagadziriswa mukati memaminitsi gumi-30. Chipatara chine mishonga nemidziyo inowanikwa nyore nyore yekugadzirisa chero matambudziko.

Chii Chinoitika Kana Dose yeEsmolol Ikasiiwa?

Kusiiwa kwe dose ye esmolol hakusi kunetseka mupfungwa dzechinyakare nekuti inopiwa se infusion inoramba ichiitwa muzvipatara. Kana infusion ikavhiringidzwa nechikonzero chipi zvacho, timu yenyu yezvokurapa ichaongorora mamiriro enyu uye ichaitazve kana zvichidikanwa.

Nekuti esmolol inoshanda nekukurumidza, hapana

Kazhinji, esmolol inombomiswa kana ropa rako uye kurova kwemoyo kwagadzikana, kuvhiyiwa kwako kana maitiro apera, kana timu yako yezvokurapa yakakuchinjisa kumishonga yenguva refu kana zvichidikanwa. Runako rweesmolol nderekuti kuimisa kuri nyore sekudzima infusion yeIV, uye mhedzisiro yayo inopera mukati memaminitsi.

Esmolol Inogona Kukonzera Mhedzisiro Yenguva Refu Here?

Esmolol kazhinji haikonzeri mhedzisiro yenguva refu nekuda kwenguva yayo pfupi yekushanda uye nguva pfupi yekushandiswa. Vanhu vazhinji vanogamuchira esmolol havana mhedzisiro inogara mushure mekunge mushonga wamiswa uye wabviswa kubva muhurongwa hwavo.

Chero chero mhedzisiro yaunowana uchigamuchira esmolol inowanzo pera mukati me10-30 maminitsi ekumisa infusion. Iyi rapid reversibility ndechimwe chezvinhu zvakakosha zvekuchengetedza izvo zvinoita kuti esmolol ive yakakosha munzvimbo dzekuchipatara. Chikwata chako chekurapa chichakutarisa mushure mekunge mushonga wamiswa kuti uve nechokwadi chekuti uri kupora zvakanaka.